ライフサイエンスコーパス: IPT

1 IPT alone does not cure existing infections in the major

2 IPT and prolonged exposure improved quality of life and

3 IPT confers protection against incident TB among HIV-neg

4 IPT for acute-phase depression had moderate-to-large eff

5 IPT had (nonsignificantly) lower attrition and higher re

6 IPT had little effect on frequencies or cytokine coexpre

7 IPT had significant effects on eating disorders, but the

8 IPT in subthreshold depression significantly prevented t

9 IPT is effective in the acute treatment of depression an

10 IPT may also be effective in the treatment of eating dis

11 IPT of malaria improves the health and cognitive ability

12 IPT reduced the incidence of malaria parasitemia and cli

13 IPT was well tolerated; the most common side effects wer

14 IPT with MQAS administered to patients with SCD during r

15 an be acquired with 185 MBq (5 mCi) of [123I]IPT.

16 165 +/- 16 MBq (4.45 +/- 0.42 mCi) of [123I]IPT.

17 f the 48 patients completed the protocol (21 IPT-A-assigned patients and 11 patients in the control g

18 ecovered at follow-up compared with 17 (27%) IPT completers.

19 Among 56 IPT-DP recipients (26 children, 30 pregnant women) with

20 ation clinic visits, 43 % (95% CI, 25%-61%); IPT and placebo, 64% (95% CI, 45%-83%); and placebo and

21 nal Psychotherapy for Depressed Adolescents (IPT-A), 48 clinic-referred adolescents (aged 12-18 years

22 cipants who were revaccinated with BCG after IPT (n = 33) or without prior IPT (n = 39).

23 Although IPT prevented malaria, the hematological benefit it adde

24 g recovery rates were equivalent for CBT and IPT at posttreatment (64 [79%] of 81 vs 59 [73%] of 81)

25 Both behavioral therapies (CBT and IPT) were manual guided and were delivered in individual

26 ot lie within blade 5 of the SEMA domain and IPT domains 2-3, both of which are thought to bind to HG

27 ough ART has been widely rolled out, ICF and IPT have not.

28 and daily iron for 12 weeks, daily iron and IPT with SP placebo, IPT and daily iron placebo, or dail

29 Combined treatment with nortriptyline and IPT was superior to IPT and placebo and showed a trend t

30 r 3 years were as follows: nortriptyline and IPT, 20% (95% confidence interval [CI], 4%-36%); nortrip

31 reatment continuation with nortriptyline and IPT.

32 aily iron placebo, or daily iron placebo and IPT with SP placebo (double placebo).

33 where malaria transmission is seasonal, and IPT an appropriate malaria intervention in children, com

34 Two months after treatment, both SPT and IPT resulted in significant reductions in serum CRP comp

35 on was induced by pollination in both WT and IPT corollas, but this increase was delayed in IPT flowe

36 oglobulin superfamily in a subclass known as IPT domains.

37 -specific efficacy of interventions, such as IPT and bacillus Calmette-Guerin (BCG) vaccination for p

38 Surgical resection of asymptomatic IPT is controversial.

39 noncurative resection of their asymptomatic IPT.

40 s (RR) for pulmonary TB associated with BCG, IPT, and latent TB infection.

41 At 2-year follow-up, both IPT and CBTgsh resulted in greater remission from binge

42 restraint decreased more quickly in CBT but IPT had equivalent levels by later follow-ups.

43 bitory potency, whereas contacts provided by IPT might strengthen the Fe-N bond.

44 d randomized controlled trials that compared IPT to placebo or alternative regimen in HIV-positive, t

45 nducted a randomized 14-week trial comparing IPT, prolonged exposure (an exposure-based exemplar), an

46 In high-incidence settings, continuous IPT should be integrated with HIV care.

47 nity volunteers could be employed to deliver IPT during the peak malaria-transmission season and also

48 proven efficacious treatment for depression (IPT).

49 In anxiety disorders, IPT had large effects compared with control groups, and

50 trates for dimethylallyl diphosphate (DMAPP) IPT activity.

51 amine fail in children by day 14, the 2-dose IPT with sulfadoxine-pyrimethamine regimen continues to

52 Four trials compared 2-dose IPT with sulfadoxine-pyrimethamine to case management or

53 Eleven IPTs were resected without a morbidity event: eight for

54 e conducted to identify all trials examining IPT for any mental health problem.

55 ed was 45% (n= 29) for CBT and 8% (n= 5) for IPT.

56 rovement of >30% in CAPS score, were 63% for IPT, 47% for prolonged exposure, and 38% for relaxation

57 re 2.8 for BWL, 2.9 for CBTgsh, and 0.73 for IPT; for self-esteem, they were 2.4 for BWL, 1.9 for CBT

58 ere 2.4 for BWL, 1.9 for CBTgsh, and 0.9 for IPT.

59 -life of piperaquine makes it attractive for IPT.

60 DP appears well tolerated and effective for IPT.

61 DP appears well tolerated and effective for IPT.

62 for SPT, P = 0.030 and 0.8 +/- 0.2 mg/L for IPT, P = 0.001).

63 CAPS outcomes for IPT and prolonged exposure differed by 5.5 points (not s

64 er, the optimal drug and dosing regimens for IPT remain to be determined.

65 The chemorepellent Sema3F is required for IPT axon pruning, dendritic spine remodeling, and repuls

66 iduals [70.5%]) was more than twice that for IPT (24 [32.0%]) (relative risk, 2.20 [95% CI, 1.51-3.22

67 per week for CGT vs 0.75 points per week for IPT [t633 = 3.85; P < .001]), and the rate of improvemen

68 s of identifying those who will benefit from IPT are needed to permit appropriate targeting of this i

69 at proportions of patients will benefit from IPT if implemented without targeting according to TST st

70 ould be classified as likely to benefit from IPT if similar frequency thresholds were applied.

71 Flowers from IPT plants were less sensitive to exogenous ethylene and

72 Group IPT is a viable alternative to group CBT for the treatme

73 compares the effects of group CBT and group IPT across BED-related symptoms among overweight individ

74 weekly sessions of either group CBT or group IPT.

75 NCLUSIONS/SIGNIFICANCE: In most settings, if IPT is administered to PLWH pre-ART without assessment o

76 or adherence interventions when implementing IPT on a wider scale.

77 ars in CMX (95% CI, 105.4-112.2) and 90.1 in IPT-SP (95% CI, 86.8-93.4) (not significant).

78 T corollas, but this increase was delayed in IPT flowers.

79 irming that floral senescence was delayed in IPT plants.

80 auxin-mediated bud inhibition, and increased IPT transcript levels are not needed for bud release fol

81 dy demonstrated noninferiority of individual IPT for PTSD compared with the gold-standard treatment.

82 refore be taken into account when initiating IPT.

83 Scale-up of TB screening at ART initiation, IPT, and ART adherence interventions could significantly

84 eived three treatments at 4-month intervals (IPT n=3535, placebo n=3223).

85 ') plants expressing ISOPENTENYLTRANSFERASE (IPT; encoding the enzyme that mediates the rate-limiting

86 sion of at least one ISOPENTENYLTRANSFERASE (IPT) CK biosynthetic gene in the stem.

87 Iodine-123-labeled IPT (N-(3-iodopropen-2-yl)-2 beta-carbomethoxy-3 beta-(4

88 spite these recommendations, household-level IPT programs are rarely implemented in high TB burden se

89 e onset of major depression, and maintenance IPT significantly reduced relapse.

90 eekly, twice-monthly, or monthly maintenance IPT monotherapy for 2 years or until a recurrence of the

91 th placebo (n = 21); and monthly maintenance IPT with nortriptyline (n = 22).

92 c with placebo (n = 29); monthly maintenance IPT with placebo (n = 21); and monthly maintenance IPT w

93 These results suggest that maintenance IPT, even at a frequency of only one visit per month, is

94 and the null hypothesis of more than minimal IPT inferiority was rejected (p=0.035).

95 Monthly IPT with DP offered remarkable protection against clinic

96 Monthly IPT-DP was associated with an 84% reduction in the incid

97 Monthly IPT-DP was associated with fewer serious adverse events

98 in their first or second pregnancy, monthly IPT resulted in less placental malaria (RR, 0.34; 95% CI

99 1 dose than were women randomized to monthly IPT (relative risk, 16.4 [95% confidence interval, 4.0-6

100 Three trials compared 2-dose with monthly IPT with sulfadoxine-pyrimethamine during pregnancy.

101 ersonal psychotherapy for depressed mothers (IPT-MOMS), a nine-session intervention based on standard

102 have an N-terminal signal peptide, multiple IPTs and PbH1 repeats, a single transmembrane span (TM),

103 5 years and one in pregnant women), and nine IPT trials (five in children younger than 5 years, one i

104 thirty-six months of isoniazid (36H) and no IPT for HIV-infected patients in India.

105 severe illness than did deferred ART and no IPT, both overall and among patients with CD4+ counts of

106 .22 for 36H at three years as compared to no IPT.

107 ively at three-year follow-up compared to no IPT.

108 .33 to 0.94) and lower with IPT than with no IPT (adjusted hazard ratio, 0.65; 95% CI, 0.48 to 0.88;

109 ly-ART strategies and between the IPT and no-IPT strategies.

110 At least 26%, and maybe up to 57%, of IPT patients of European-American descent carried possib

111 The combination of IPT and iron supplementation was most effective in the t

112 as being at higher risk of non-completion of IPT.

113 Thirty patients with diagnoses of IPT underwent standard ophthalmologic evaluation that in

114 sought to measure the radiation dosimetry of IPT in seven healthy human volunteers.

115 ebo iron, after adjustment for the effect of IPT-SP, was 9.1 g/L (95% CI: 6.4, 11.8) and 8.2 g/L (4.0

116 or limiting the rollout and effectiveness of IPT and ICF is the limitations of existing tools to both

117 Further, the cost-effectiveness of IPT has not been studied in India.

118 l randomized trials examining the effects of IPT for all mental health problems was conducted.

119 We estimate the age-specific efficacy of IPT and BCG for preventing TB disease using data from a

120 sulfadoxine-pyrimethamine on the efficacy of IPT during pregnancy in Africa.

121 Data on the efficacy of IPT with sulfadoxine-pyrimethamine on placental and peri

122 Efficacy of IPT with sulfadoxine-pyrimethamine was lower among women

123 In addition, O-Man glycosylation of IPT/TIG domains of plexins and hepatocyte growth factor

124 e impact of community-wide implementation of IPT for TB-HIV coinfected individuals on the dynamics of

125 f TST is not a requirement for initiation of IPT.

126 were acquired with about 185 MBq (5 mCi) of IPT on a triple-headed camera.

127 rican country, immediate ART and 6 months of IPT independently led to lower rates of severe illness t

128 The aim was to evaluate predictors of IPT non-completion.

129 rteen patients had 1-hour weekly sessions of IPT from the same supervised therapist (E.M.).

130 Intervention Twenty sessions of IPT or BWL or 10 sessions of CBTgsh during 6 months.

131 d, double-blind, placebo-controlled trial of IPT was done in 30 primary schools in western Kenya.

132 Nine trials of IPT with sulfadoxine-pyrimethamine during pregnancy in A

133 The specific uptake of IPT was higher in the caudate than in the putamen of eac

134 aracterize changes in the striatal uptake of IPT with normal aging.

135 These findings support the use of IPT in older children and young-adult household contacts

136 , acceptability, and efficacy of 12 weeks of IPT-A in acutely depressed adolescents in reducing depre

137 h latent tuberculosis infection were offered IPT.

138 Sixteen sessions of CGT (n = 74) or IPT (n = 77) delivered approximately weekly.

139 ed at random to 19 sessions of either CBT or IPT conducted over a 20-week period and evaluated for 1

140 ry 7, 2013, and randomized to receive CGT or IPT.

141 Of 264 women randomly assigned to the CMX or IPT-SP group, 126 of 132 and 124 of 132, respectively, w

142 omly assigned to daily 800 mg/160 mg CMX, or IPT-SP.

143 maintenance treatment with nortriptyline or IPT is superior to placebo in preventing or delaying rec

144 to receive daily treatment with proguanil or IPT with either MQAS or SPAQ once every 2 months at rout

145 eening for TB, and providing TB treatment or IPT in adults testing HIV positive in Sub-Saharan Africa

146 h protein-protein interaction sites on other IPT domains but that it is completely different from the

147 who require the addition of pharmacotherapy, IPT monotherapy represents a significantly less efficaci

148 2 weeks, daily iron and IPT with SP placebo, IPT and daily iron placebo, or daily iron placebo and IP

149 ccording to WHO criteria), deferred ART plus IPT, early ART (immediate ART initiation), or early ART

150 immediate ART initiation), or early ART plus IPT.

151 venlafaxine, 22.4 [3.1]; and posttreatment: IPT, 16.2 [7.1], and venlafaxine, 10.9 [8.6]).

152 ine (mean [SD] HAM-D scores at pretreatment: IPT, 22.7 [2.7], and venlafaxine, 22.4 [3.1]; and posttr

153 with BCG after IPT (n = 33) or without prior IPT (n = 39).

154 rth hotspot revealed a region across the PSI-IPT 1 domains not previously associated with HGF binding

155 directed against SEMA blades 2-3 and the PSI-IPT 1 region inhibited brain invasion and prolonged surv

156 Interpersonal psychotherapy (IPT) has been developed for the treatment of depression

157 Interpersonal psychotherapy (IPT) has been shown to reduce binge eating but its long-

158 Interpersonal psychotherapy (IPT) is an effective specialty treatment for binge eatin

159 suggested that interpersonal psychotherapy (IPT) might be as effective as CBT, although slower to ac

160 drochloride and interpersonal psychotherapy (IPT) might each alter brain blood flow in some or all of

161 to 12 weeks of interpersonal psychotherapy (IPT) or to a waiting list condition (WLC) control group.

162 er frequency of interpersonal psychotherapy (IPT) sessions during maintenance treatment has a greater

163 authors tested interpersonal psychotherapy (IPT), which has demonstrated antidepressant efficacy and

164 ink-strength, we identified several putative IPT genes using a bioinformatics approach.

165 mptomatic older children who did not receive IPT.

166 n Patients were randomly assigned to receive IPT-A (n = 34) or TAU (n = 29) from school-based health

167 Inventory (BDI) scores of women who received IPT declined from 23.6 to 10.6 over 12 weeks, a signific

168 tly greater proportion of women who received IPT recovered from their depressive episode based on HRS

169 nt illness episodes in children who received IPT than those who received proguanil.

170 sample, 18 (75%) of 24 patients who received IPT-A compared with 11 patients (46%) in the control con

171 Patients who received IPT-A reported a notably greater decrease in depressive

172 Among 262 inmates receiving IPT upon release from jail, 105 (40%) could not be locat

173 Women receiving IPT also had significant improvement on the Postpartum A

174 Depression (HRSD) scores of women receiving IPT declined from 19.4 to 8.3, a significantly greater d

175 The signaling events that regulate IPT axon pruning are not known.

176 nia (Petunia x hybrida cv V26) with P(SAG12)-IPT.

177 was induced under drought stress in P SARK ::IPT plants.

178 f transgenic rice plants expressing P SARK ::IPT, validated by qPCR, indicated that OsWRKY47 expressi

179 We investigated the effects of P(SARK)IPT (for Senescence-Associated Receptor KinaseIsopenteny

180 leaves from wild-type and transgenic P(SARK)-IPT plants grown under optimal or restricted watering.

181 rbon assimilation in the transgenic P(SARK)::IPT plants was well correlated with enhanced nitrate con

182 ffected by stress in the transgenic P(SARK)::IPT plants.

183 SP-IPT in infants and pregnant women is reported to have fa

184 tionship between resistance mutations and SP-IPT within target populations in the context of monitori

185 super resistant areas prompting review of SP-IPT use in affected areas.

186 Combined treatment was more effective than IPT alone (g=0.24).

187 vement in patients with bulimia nervosa than IPT.

188 ontrol groups, and there is no evidence that IPT was less effective than CBT.

189 The authors hypothesized that IPT would be no more than minimally inferior (a differen

190 The findings showed that IPT was excreted rapidly by the renal system.

191 These findings suggest that IPT is an efficacious treatment for postpartum depressio

192 The IPT group also showed a decrease in total and LDL choles

193 The IPT reduced placental malaria (relative risk [RR], 0.48;

194 ART and early-ART strategies and between the IPT and no-IPT strategies.

195 dL (95% CI, -0.15-0.49 g/dL) greater for the IPT group.

196 terval [CI], 0.82-1.47 g/dL) greater for the IPT+iron group, 0.79 g/dL (95% CI, 0.46-1.10 g/dL) great

197 showed that compared with the TAU group, the IPT-A group showed significantly fewer clinician-reporte

198 ted alleles in CFH, CFB, and 10q loci in the IPT cohort were similar to those in the ethnically match

199 of anaemia at 12 months averaged 6.3% in the IPT group and 12.6% in the placebo group (adjusted risk

200 2604 children in the IPT group and 2302 in the placebo group were included in

201 d within 28 days of any treatment (19 in the IPT group and four in the placebo group); the main side-

202 35.2%] in the CGT group vs 41 [64.1%] in the IPT group were still at least moderately ill [P = .001])

203 al malaria in the CMX group vs. 24.6% in the IPT-SP group (not significant).

204 mia was 16.7% in the CMX group vs 28% in the IPT-SP group (P = .02).

205 the CMX group and 105 of 124 (84.7%) in the IPT-SP group remained malaria-free during their pregnanc

206 the CMX group, and 19 among 19 women in the IPT-SP group.

207 in transgenic plants, the expression of the IPT gene under control of senescence-associated promoter

208 Adherence to the IPT regimens was excellent, but 57% of patients took <75

209 cause of symptoms at or death related to the IPT.

210 basal ganglia activation (P =.01), while the IPT group had limbic right posterior cingulate and right

211 ard (SPT) and intensive periodontal therapy (IPT) on serum inflammatory markers and cholesterol level

212 duals, where isoniazid preventative therapy (IPT) is given to those screening negative, and use value

213 olled trial of isoniazid preventive therapy (IPT) before revaccination with bacillus Calmette-Guerin

214 ion recommends isoniazid preventive therapy (IPT) for HIV-positive contacts and those younger than 5

215 Isoniazid preventive therapy (IPT) for HIV-TB coinfected individuals reduces the react

216 Trials of isoniazid preventive therapy (IPT) for people living with HIV in southern Africa have

217 mens for isoniazid-based preventive therapy (IPT) for tuberculosis (TB) in HIV-infected individuals h

218 ) who received isoniazid preventive therapy (IPT) had developed disease compared with 4 of 149 (2.6%)

219 ng or prior to isoniazid preventive therapy (IPT) in patients infected with human immunodeficiency vi

220 completion of isoniazid preventive therapy (IPT) in those persons after their discharge from short-t

221 Isoniazid preventive therapy (IPT) is recommended as preventive therapy in HIV-infecte

222 Isoniazid preventive therapy (IPT) was prescribed to <1% of ART enrollees not taking T

223 ) benefit from isoniazid preventive therapy (IPT) whereas those testing TST-negative do not.

224 (ART), 6-month isoniazid preventive therapy (IPT), or both among HIV-infected adults with high CD4+ c

225 apy (ART), and isoniazid preventive therapy (IPT).

226 ed nets and intermittent preventive therapy (IPT).

227 he-2) and removal of the isopropyl-thiazole (IPT) moiety affect affinity, inhibitory potency, and the

228 se significantly more than those assigned to IPT (P<.01 for both).

229 ychiatric treatment and randomly assigned to IPT-MOMS (N=26) or treatment as usual (N=21).

230 usual, the offspring of mothers assigned to IPT-MOMS showed significantly lower levels of depression

231 to treatment as usual, subjects assigned to IPT-MOMS showed significantly lower levels of depression

232 Assignment to IPT-MOMS was associated with reduced levels of maternal

233 Daily CMX was not noninferior to IPT-SP for preventing maternal malaria but safe and at l

234 d be prudent to do a sputum culture prior to IPT where this is feasible.

235 ART and on ART undergoing screening prior to IPT.

236 survival (OS) and minor morbidity related to IPT requiring hospitalization, transfusion, or nonsurgic

237 , perforation, bleeding, or death related to IPT.

238 tients (14%) with major morbidity related to IPT: 10 required surgery (eight, obstruction; one, perfo

239 t with nortriptyline and IPT was superior to IPT and placebo and showed a trend to superior efficacy

240 vioral therapy was significantly superior to IPT at the end of treatment in the percentage of partici

241 ) and extend along the infrapyramidal tract (IPT) occurs during postnatal murine development by neuri

242 okinin-synthesizing isopentenyl transferase (IPT) enzyme under the control of the Arabidopsis senesce

243 s, the discovery of isopentenyl transferase (IPT) genes in plants has shed light on the CK biosynthes

244 n with homology to isopentenyl transferases (IPTs), also causes CK-specific effects when expressed in

245 Intermittent preventive treatment (IPT) for malaria is used in infants, children, adults, a

246 effect of intermittent preventive treatment (IPT) in reducing anaemia and improving classroom attenti

247 Intermittent preventive treatment (IPT) in schoolchildren offers a promising option for mal

248 Intermittent preventive treatment (IPT) of malaria has recently been shown to be a highly e

249 frica for intermittent preventive treatment (IPT) of malaria, but resistance threatens its efficacy.

250 t whether intermittent preventive treatment (IPT) with a fixed-dose combination of mefloquine-artesun

251 by either intermittent preventive treatment (IPT) with SP at 4 and 8 weeks and daily iron for 12 week

252 Intermittent preventive treatment (IPT) with sulphadoxine-pyrimethamine in vulnerable popul

253 methamine intermittent preventive treatment (IPT-SP) on malaria risk in HIV-positive pregnant women i

254 carbomethoxy-3 beta-(4-chlorophenyl)tropane (IPT) is an analog of cocaine that selectively binds the

255 g with an asymptomatic intact primary tumor (IPT) and synchronous yet unresectable metastatic disease

256 indirectly, through hormone regulation using IPT and ESR1, has improved rates of stable transformatio

257 .05; odds ratios: BWL vs CBTgsh, 2.3; BWL vs IPT, 2.6; and CBTgsh vs IPT, 1.2).

258 CBTgsh, 2.3; BWL vs IPT, 2.6; and CBTgsh vs IPT, 1.2).

259 rder were randomly assigned to either weekly IPT-A or clinical monitoring.

260 ticipants had achieved remission with weekly IPT or, if required, with weekly IPT plus antidepressant

261 with weekly IPT or, if required, with weekly IPT plus antidepressant pharmacotherapy, they were rando

262 We conclude that community-wide IPT in areas of emerging HIV and drug-resistant TB shoul

263 We found that community-wide IPT will reduce the incidence of TB in the short-term bu

264 zed that preclearance of latent bacilli with IPT modulates BCG immunogenicity following revaccination

265 ment option for most patients with BED, with IPT (or full cognitive behavior therapy) used for patien

266 morbid major depression may fare better with IPT than with prolonged exposure.

267 on has shown limbic blood flow increase with IPT yet not venlafaxine, while both treatments demonstra

268 , 0.56; 95% CI, 0.33 to 0.94) and lower with IPT than with no IPT (adjusted hazard ratio, 0.65; 95% C

269 xis for women who can achieve remission with IPT alone.

270 Among participants who remitted with IPT alone and entered maintenance treatment (N=99), 19 (

271 Adolescents treated with IPT-A compared with TAU showed greater symptom reduction

272 week with CGT and 0.39 points per week with IPT [t503 = 2.87; P = .004]).

273 Without IPT, projected life expectancy was 136.1 months at a lif