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1 IPV induced small but significant decreases in a composi
2 IPV-based protection alone might not provide sufficient
3 IPV-bOPV schedules resulted in almost a 0.3 log reductio
4 IPV-immunized mice were protected against WPV1-induced p
5 IPV-related firearm laws (predictor) and annual, state-s
8 type 2), and 98.5% (n=202, type 3); and 1/10 IPV-Al: 98.5% (n=201, type 1), 94.6% (n=193, type 2), an
9 e [1/5 IPV-Al], ten-times reduced dose [1/10 IPV-Al], or IPV) intramuscularly in the thigh at 6, 10,
11 ded programme of immunisation schedule): 1/3 IPV-Al 98.5% (n=202, type 1), 97.6% (n=200; type 2), and
12 s; 205 were randomly assigned to receive 1/3 IPV-Al, 205 to receive 1/5 IPV-Al, 204 to receive 1/10 I
13 formulations (three-times reduced dose [1/3 IPV-Al], five-times reduced dose [1/5 IPV-Al], ten-times
14 ed to receive 1/3 IPV-Al, 205 to receive 1/5 IPV-Al, 204 to receive 1/10 IPV-Al, and 206 to receive I
15 200; type 2), and 99.5% (n=204, type 3); 1/5 IPV-Al: 99.5% (n=204, type 1), 96.1% (n=197, type 2), an
16 e [1/3 IPV-Al], five-times reduced dose [1/5 IPV-Al], ten-times reduced dose [1/10 IPV-Al], or IPV) i
18 which limited countries' abilities to access IPV in a timely manner, 105 of 126 countries using OPV o
21 IPV, by June all LGAs had HFs administering IPV and by July, 91% of the HFs in Kano reported adminis
22 f LGAs had at least 20% of HFs administering IPV, by June all LGAs had HFs administering IPV and by J
25 We aimed to analyse adverse events after IPV administration reported to the US Vaccine Adverse Ev
27 Sudden infant death syndrome reports after IPV were consistent with reporting patterns for other va
29 ontaining IPV and bOPV, compared with an all-IPV schedule, and proportions of infants with protective
30 V-containing schedules compared with the all-IPV schedule for seroconversion (within a 10% margin) an
31 V-containing schedules compared with the all-IPV schedule, with no significant differences between gr
32 s remained elevated 6 and 11 months after an IPV boost, although at a lower level than reported at 1
33 IPV/OPV schedule instead of switching to an IPV-only schedule in 2005 would have kept population imm
35 of two schedules of bivalent OPV (bOPV) and IPV and challenge with monovalent type 2 OPV, and stools
38 irus in the IPV-bOPV-bOPV, IPV-IPV-bOPV, and IPV-IPV-IPV groups, respectively, were 130 (77.4%) of 16
40 rrhea was not different between the tOPV and IPV groups (P = .18), the number of days with diarrhea (
41 ne to 12 weeks, the number of women with any IPV in the past week decreased from 57% (134 of 237) in
42 ber of administrations of a vaccine, such as IPV, this technology can serve as a tool to aid in the e
47 g to type 2 poliovirus in the IPV-bOPV-bOPV, IPV-IPV-bOPV, and IPV-IPV-IPV groups, respectively, were
49 ective was to assess the superiority of bOPV-IPV schedules over bOPV alone, as assessed by the primar
51 (tOPV at 6, 10, and 14 weeks), and the bOPV-IPV group (bOPV at 6, 10, and 14 weeks plus IPV at 14 we
52 ered in the Western Pacific Region with both IPV introduction and the tOPV-bOPV switch were related t
54 -inferior in sequential schedules containing IPV and bOPV, compared with an all-IPV schedule, and pro
57 been ongoing since 2014, including delaying IPV introduction in countries where risks of type 2 rein
59 assessed the immunogenicity of two different IPV-bOPV schedules compared with an all-IPV schedule in
60 tered intradermally, compared with full-dose IPV administered intramuscularly, among adults with a hi
63 in the alternating limb group received DTaP-IPV-Hib in the left leg at 2 months and in the right leg
64 lus influenzae type b combined vaccine (DTaP-IPV-Hib) at 2, 3, and 4 months of age, and the pneumococ
65 ers in Southern England immunized with DTaP5/IPV/Haemophilus influenzae b (Hib-TT) vaccine at 2-3-4 m
67 o-glycolic acid) (PLGA) that can encapsulate IPV along with stabilizing excipients and release immuno
69 Incidents of heavy drinking and experiencing IPV measured over prespecified, 12 weekly assessments us
70 group on weekly assessments for experiencing IPV (odds ratio [OR], 1.02; 95% CI, 0.98-1.06) or heavy
74 ne production and an unforecasted demand for IPV use in campaigns to interrupt wild polio virus and t
76 ctiveness of a motivational intervention for IPV-involved female ED patients (ages: 18-64 years; N =
78 to provide exceptional financial support for IPV introduction to additional OPV-only using countries
79 y block-size of four, to receive one of four IPV formulations (three-times reduced dose [1/3 IPV-Al],
80 izing wastage and use of a 2-dose fractional-IPV schedule could extend IPV immunization to more child
85 aring strategy to stretch the limited global IPV supply while further improving population immunity.
91 ed that a one-standard-deviation increase in IPV intensity was associated with a 12.3% relative incre
94 ve-attenuated oral (OPV) and/or inactivated (IPV) PV vaccines have systematically reduced its spread
104 obal polio eradication strategy to introduce IPV into the immunisation schedules of all countries.
106 n 2014 and 2016, 11 EMR countries introduced IPV in their routine immunization program, including all
108 A total of 105 countries have introduced IPV as of September 2016 of which 85 have procured the v
109 5 of 126 countries using OPV only introduced IPV within a 2.5-year period, making it the fastest roll
112 the IPV-bOPV-bOPV, IPV-IPV-bOPV, and IPV-IPV-IPV groups, respectively, the proportions of children wi
113 the IPV-bOPV-bOPV, IPV-IPV-bOPV, and IPV-IPV-IPV groups, respectively, the proportions of children wi
114 the IPV-bOPV-bOPV, IPV-IPV-bOPV, and IPV-IPV-IPV groups, respectively, were 130 (77.4%) of 168, 95% C
117 tations, we found that BAG3 uses both of its IPV motifs to interact with sHsps, including Hsp27 (HspB
118 me-fixed and time-varying covariates, lagged IPV intensity had a statistically significant associatio
119 tematic review identified 13 studies linking IPV to incident depression, none of which were conducted
120 terial etiology (P = .0099) compared to male IPV recipients but equally likely to experience diarrhea
122 5) of the assessed control group reported no IPV during the previous 3 months and 19% (29 of 152) of
126 data support the future co-administration of IPV, measles-rubella, and yellow fever vaccines within t
128 ssment approaches were used: (1) analysis of IPV vaccinations reported in NHMIS, and (2) survey of 20
129 te adjusted prevalence risk ratios (aPRR) of IPV, and adjusted incidence rate ratios (aIRR) of HIV ac
130 assess whether provision of a combination of IPV prevention and HIV services would reduce IPV and HIV
131 s to decrease the effective dose and cost of IPV, but prior studies, all using 20% of the standard do
132 results suggest that intradermal delivery of IPV may lead to dose-sparing effect and reduction of the
133 s comparable to that of the standard dose of IPV administered intramuscularly and resulted in higher
134 eeks; group 4 received bOPV plus one dose of IPV at 14 weeks; and group 5 received bOPV plus two dose
135 0 weeks, and 14 weeks and either one dose of IPV at age 14 weeks or two doses of IPV at age 14 weeks
136 ats that received 1/40th of a human dose of IPV delivered by Nanopatch, but not in rats given 1/8th
139 With most countries opting for one dose of IPV in routine immunisation schedules during this transi
140 e rapid introduction of at least one dose of IPV into routine immunization schedules in 126 all OPV-u
141 2:2:1 to receive 40% of the standard dose of IPV intradermally, 20% of the standard dose intradermall
142 infants) were allocated bOPV and one dose of IPV, and 22 villages (329 infants) were assigned bOPV an
144 immunised with bOPV and one or two doses of IPV and those who received tOPV (15 of 252 [6%] vs six o
147 on of single fractional intradermal doses of IPV by needle and syringe or disposable-syringe jet inje
148 nificantly with bOPV and one or two doses of IPV compared with tOPV (17 of 751 [2%] vs three of 353 [
149 generated by fractional intradermal doses of IPV did not achieve non-inferiority compared with full d
151 eceiving bOPV and either one or two doses of IPV, but transmission was not increased in the community
156 al examined the safety and immunogenicity of IPV given alongside the measles-rubella and yellow fever
159 the lessons learned from the introduction of IPV and the switch from tOPV to bOPV can be useful for t
160 role played by NITAGs in the introduction of IPV in the routine immunization program and the lessons
164 Men reported more lifetime perpetration of IPV (physical or sexual IPV range 32.5%-80%) than women
165 omen from human rights abuses, prevention of IPV, reduction in insecurity and poverty in the post-con
166 his article is to systematize the process of IPV introduction and switch in Latin America and the Car
168 ntions of arm B with additional provision of IPV delivered at the maternal and child health camps (ar
169 nd acceptance of the recommended schedule of IPV by the SAGE, but the evidence was largely from devel
170 en delayed because of the global shortage of IPV, making it unavailable to select lower-risk countrie
172 sional societies, thus encouraging uptake of IPV as a second or third injection in an accelerated man
176 measures for the study were coverage of OPV, IPV, and routine extended programme on immunisation vacc
177 l], ten-times reduced dose [1/10 IPV-Al], or IPV) intramuscularly in the thigh at 6, 10, and 14 weeks
181 4 weeks after vaccination with mIPV2HD or IPV, seroconversion to poliovirus type 2 was recorded in
182 us 4 weeks after vaccination with mIPV2HD or IPV; and safety (as determined by the proportion and nat
184 evalence rates of past-year male-perpetrated IPV and nonpartner rape from women's and men's reports a
186 perience of past-year sexual and/or physical IPV: (1) poverty, (2) all childhood trauma, (3) quarrell
187 had fewer self-reports of past-year physical IPV (346 [16%] of 2127 responders in control groups vs 2
189 poliovirus (OPV) or inactivated poliovirus (IPV) vaccines and mixed schedules thereof will determine
191 1-4 years were randomized (1:1:1) to receive IPV at 5 months (arm A), at enrollment (arm B), or no va
194 clustering of children who have not received IPV is expected in sub-Saharan Africa and Asia if IPV is
195 uring a single visit, with infants receiving IPV alongside pentavalent vaccine (which covers diphther
196 additional 12 million children not receiving IPV if IPV is offered with DTP3, rather than with DTP1.
197 Intensive health sector responses to reduce IPV and improve women's mental health should be explored
198 IPV prevention and HIV services would reduce IPV and HIV incidence in individuals enrolled in the Rak
205 ups; aPRR 0.79, 95% CI 0.67-0.92) and sexual IPV (261 [13%] of 2038 vs 167 [10%] of 1737; 0.80, 0.67-
206 ciated with past-year physical and/or sexual IPV exposure; of particular interest is the resilience p
207 s experience of past-year physical or sexual IPV from women's reports and factors driving women's pas
209 han women did experience (physical or sexual IPV range 27.5%-67.4%), but women's reports of past-year
210 time perpetration of IPV (physical or sexual IPV range 32.5%-80%) than women did experience (physical
211 of past-year experience (physical or sexual IPV range 8.2%-32.1%) were not very clearly different fr
219 ated paralytic polio, financially sustaining IPV introduction, ensuring equitable access to IPV, and
223 Our most comprehensive model showed that IPV and conflict-related deprivations led directly to de
224 ical work and stakeholder consultations, the IPV Immunization Systems Management Group (IMG) presente
226 86 (74.8%, 65.8-82.4) of 115 infants in the IPV group (difference between groups 18.3%, 95% CI 5.0-3
227 the mIPV2HD group and 36 (18.0-113.8) in the IPV group (difference between groups 98.8, 95% CI 60.7-1
228 D group and seven (6%) of 116 infants in the IPV group during the 8-week period after vaccination; no
229 n seroconverting to type 2 poliovirus in the IPV-bOPV-bOPV, IPV-IPV-bOPV, and IPV-IPV-IPV groups, res
232 formulations, 1.4, 1.1, and 1.2 doses of the IPV serotype 1, 2, and 3, respectively, were released wi
233 accine were randomly assigned to receive the IPV, measles-rubella, and yellow fever vaccines, singula
234 ticle, and based on lessons learned with the IPV introductions, it is recommended for future health p
237 s 1, 2, and 3 was already high for the three IPV-Al vaccines after two vaccinations, but was higher a
239 we assigned 570 infants to treatment: 190 to IPV-bOPV-bOPV, 192 to IPV-IPV-bOPV, and 188 to IPV-IPV-I
242 V introduction, ensuring equitable access to IPV, and preparing for future OPV cessation following gl
244 des, social norms, and behaviours related to IPV, and a screening and brief intervention to promote s
245 State laws that prohibit persons subject to IPV-related restraining orders from possessing firearms
247 ed, 3-y cluster-randomized controlled trial, IPV had a statistically significant association with dep
248 dose of either mIPV2HD or standard trivalent IPV given concurrently with a third dose of bOPV at 14 w
253 the end of 2016 all EMR countries were using IPV except Egypt, where introduction of IPV was delayed
254 (1:1:1) to receive three polio vaccinations (IPV by injection or bOPV as oral drops) at age 8, 16, an
256 troduction of the inactivated polio vaccine (IPV) and the switch from trivalent oral polio vaccine (t
257 a have introduced inactivated polio vaccine (IPV) as part of the Global Polio Eradication and Endgame
259 orts to introduce inactivated polio vaccine (IPV) into all countries that did not yet include it in t
260 lbania introduced inactivated polio vaccine (IPV) into its immunization system in May 2014, increasin
261 geria, introduced inactivated polio vaccine (IPV) into its routine immunization (RI) schedule in Marc
262 t least 1 dose of Inactivated Polio Vaccine (IPV) into routine immunization schedules by the end of 2
263 t least 1 dose of inactivated polio vaccine (IPV) into the routine immunization programs of all count
264 t least 1 dose of inactivated polio vaccine (IPV) into their routine immunization schedules by the en
267 sets, introducing inactivated polio vaccine (IPV), and replacing trivalent oral polio vaccine with bi
268 es, including the inactivated polio vaccine (IPV), must be injected more than once for efficacy.
271 1 dose of inactivated poliomyelitis vaccine (IPV); withdraw oral poliomyelitis vaccine (OPV), startin
272 s' uptake of inactivated poliovirus vaccine (IPV) after its introduction into the routine immunizatio
273 n the use of inactivated poliovirus vaccine (IPV) are important for the global polio eradication stra
274 roduction of inactivated poliovirus vaccine (IPV) are major steps in the polio endgame strategy.
275 showed that inactivated poliovirus vaccine (IPV) boosts intestinal immunity in children previously i
276 nal doses of inactivated poliovirus vaccine (IPV) delivered intradermally to induce levels of serum p
278 one dose of inactivated poliovirus vaccine (IPV) in routine immunisation programmes to eliminate vac
281 ction of the inactivated poliovirus vaccine (IPV) represents a crucial step in the polio eradication
283 ole of using inactivated poliovirus vaccine (IPV) to manage the risks of circulating vaccine-derived
284 PV) in 2016, inactivated poliovirus vaccine (IPV) will be the only source of protection against polio
287 male-perpetrated intimate partner violence (IPV) and risk factors is essential for building evidence
289 ogical impacts of intimate partner violence (IPV) is derived primarily from studies conducted in high
291 ng these factors, intimate partner violence (IPV), and continuing adversity in women in Timor-Leste.
293 We analysed all VAERS data associated with IPV submitted between Jan 1, 2000, and Dec 31, 2012, eit
294 ng of adverse events after immunisation with IPV-containing vaccines compared with other vaccines bet
298 (97%) were for simultaneous vaccination with IPV and other vaccines (most commonly pneumococcal and a
299 ted experience and perpetration of past year IPV (emotional, physical, and sexual) and laboratory-bas
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