ライフサイエンスコーパス: IS element

1 in the stable genomic sites which flank the IS element.

2 quences in a manner unlike that of any other IS element.

3 kov models constructed from manually curated IS elements.

4 high-throughput tool for a global search of IS elements.

5 permine-responsive promoter contained within IS elements.

6 ed based on the previously identified ~1,500 IS elements.

7 consistent with the NCBI annotations of the IS elements.

8 karyotic genomes with curated annotations of IS elements.

9 lso detected 48 long deletions not involving IS elements.

10 een described with such a high proportion of IS elements.

11 ted ISPg5, has features of the IS3 family of IS elements.

12 rect repeats had not been observed for other IS elements.

13 0 kb region separated by insertion sequence (IS) elements.

14 on of direct repeats and insertion sequence (IS) elements.

15 genetic elements such as insertion sequence (IS) elements.

16 replicon, and two intact insertion sequence (IS) elements.

17 al chromosomal genes (88 to 98%) or in other IS elements (95 to 97% for IS605, IS606, and IS607) from

18 e, the genome harbors 73 insertion sequence (IS) elements, almost all of which are closely related to

19 study, a 7.5-kb region positioned within the IS elements and downstream of abiA was sequenced to reve

20 Taken together, similarities in IS elements and H. pylori population genetic structures

21 mology to transposases of the IS30 family of IS elements and is most closely related (27% identical a

22 ufficient to activate transcription of these IS elements and of nearby genes in broth culture and in

23 we report novel insertions and excisions of IS elements and recombination between homologous IS elem

24 These genetic maps of recently active IS elements and the several interesting observations wou

25 Mobile genetic elements in the form of IS elements and transposons are prominent in the genome

26 for mutations involving insertion sequence (IS) elements and identified two genes where multiple lin

27 transposons, integrons, insertion sequence (IS) elements and the 'new' ISCR (IS common region) eleme

28 y to tRNA genes, (ii) a previously described IS element, and (iii) a novel IS-like element.

29 in sequences interrupted by the insertion of IS elements, and (iv) pre-dictions that 92 genes are par

30 Here, we present a new IS elements annotation pipeline to address these issues.

31 IS elements appear to have remodeled genome architecture

32 Several vestigial IS elements appeared different from the IS distribution

33 This rickettsial IS element appears to be active in that complete termina

34 The features of these two chimaeric IS elements are discussed in terms of possible transposi

35 h B and K, 16 in common, and likely founding IS elements are identified.

36 Three IS elements are located near the first gene of the 2,4,5

37 the flanking regions of the recently active IS elements are significantly enriched with genes encodi

38 The insertion sequence (IS) elements are the smallest but most abundant autonomo

39 We found that insertion sequence (IS) elements are unusually abundant in the relatively re

40 transposase protein, the insertion elements (IS elements) are similar to IST2 of Thiobacillus ferroox

41 Prokaryotic insertion sequence (IS) elements behave like parasites in terms of their abi

42 son defined by inverted repeats of a 1347 bp IS element belonging to a recently discovered family whi

43 the correct answer ("inlying" elements; that is, elements closer to the reference value).

44 Both IS elements contain a single open reading frame (ORF) en

45 complete copy of the previously unidentified IS element, designated PGIS2, had inserted into IS4351R

46 terms of possible transposition mechanisms, IS element evolution, and effects of IS elements on geno

47 we targeted the intronic silencing sequence (ISS) elements flanking the alternatively spliced alpha-e

48 (IS) element, IS1629, with homology to other IS elements from prokaryotic animal pathogens.

49 s of two other H. pylori insertion sequence (IS) element genes, orfA, which encodes a putative serine

50 The numerous IS elements, genomic rearrangements, and pseudogenes of

51 Simultaneous targeting of the ISS elements had no additive effect, suggesting that spl

52 lutionary event in which transposition of an IS element has a direct impact on virulence gene regulat

53 The pCoo DNA between these IS elements has a wide range of G+C content (35 to 57%),

54 ination between abundant insertion sequence (IS) elements has resulted in genome plasticity manifeste

55 orn out of gas with few or no 'metals' (that is, elements heavier than helium).

56 ditions, we found that (a) the activities of IS elements heavily depend on the environments where the

57 gment of aqpZ and additional full or partial IS elements (i.e., IS629, IS91, and IS911) downstream of

58 Further sequencing identified partial IS elements (i.e., IS91 and IS630) and wzz upstream of t

59 lements and recombination between homologous IS elements identified in a large collection of Escheric

60 isms live; (b) the number of recently active IS elements in a genome tends to increase with the genom

61 More than 50 sites are occupied by IS elements in both B and K, 16 in common, and likely fo

62 rtion Sequences and IScan currently identify IS elements in completely assembled and annotated genome

63 1485, FB8, MM294, and RB791) did not contain IS elements in the flhD regulatory region and were poorl

64 ides targeting either upstream or downstream ISS elements increased alpha-exon inclusion from 10% up

65 f commonly used lab strains was screened for IS element insertion and motility.

66 ormatic analysis raises the possibility that IS element insertion in this region represents an adapti

67 We suggest that IS element insertion may activate transcription of the f

68 due to loss of bacteriophage sequences after IS element insertions and rearrangements.

69 enes are generated by nonsense mutations and IS element insertions, events that seldom produce the ps

70 onal start site of flhD was unaltered by the IS element insertions.

71 An IS element is inserted into the rrs gene of one of only

72 However, our knowledge of this IS element is relatively limited; even its two basic cha

73 These events are mostly contributed by the IS elements IS1, IS2, IS5 and IS186 Spatial analysis of

74 ersed among three intact insertion sequence (IS) elements (IS100 and two new IS elements, IS1616 and

75 bp upstream of the P. gingivalis endogenous IS element IS1126.

76 n5506 contained a single insertion sequence (IS) element, IS1216V2, whereas the right end was compose

77 on sequence (IS) elements (IS100 and two new IS elements, IS1616 and IS1617) and numerous defective o

78 s 84.34 identified a new insertion sequence (IS) element, IS1629, with homology to other IS elements

79 putative transposases of two other unrelated IS elements (IS200 and IS1341), was found in nearly one-

80 re linked by a series of insertion sequence (IS) elements (IS256, IS257, and IS1216) of staphylococca

81 It contains 12 and 14 copies of two novel IS elements, ISAba25 and ISAba26, respectively.

82 re due to a 312-bp fragment derived from the IS element ISFtu1.

83 o classes of Francisella insertion sequence (IS) elements, ISFtu1 and ISFtu2, and the genes adjacent

84 i, we identified a novel insertion sequence (IS) element, ISRpe1, disrupting the coding sequence of r

85 One intact IS element, ISYen1, was a new IS belonging to the IS256

86 cus, however, correlated with differences in IS element location.

87 This suggests that ISPg5 and other IS elements may contribute to strain diversity and can b

88 found, suggesting that pNRC100 evolved from IS element-mediated fusions of several smaller plasmids.

89 A multi-step IS element-mediated process is proposed to account for t

90 een acquired by bacteriophage integration or IS element-mediated transposition.

91 undergoes high-frequency insertion sequence (IS) element-mediated insertions and deletions, as well a

92 ed to known and putative insertion sequence (IS) elements; no known bacterial plasmid has previously

93 was demonstrated by similar targeting of the ISS elements of the human hnRNPA1 gene.

94 anisms, IS element evolution, and effects of IS elements on genome organization and evolution in the

95 The genome also contains insertion sequence (IS) elements, phage remnants, and many other patches of

96 Our results confirm the hypothesis that IS elements play a central role in transcription of 2,4,

97 uld help to improve our understanding of how IS elements proliferate and how they are involved in the

98 gene nor evidence for classically organized IS elements, prophages, or plasmids.

99 The unique spatial location of specific IS elements provided the basis for the development of a

100 ,346-bp circle, has shown the presence of 27 IS elements representing eight families.

101 These IS-element-rich regions of the genome may serve to excha

102 wer GC composition and overrepresentation of IS elements, similar to the minichromosomes.

103 ates the first on-line detection system that is element-specific, nondestructive, and directly applic

104 ctures and evidence of adaptive evolution in IS elements suggest that there is coevolution between th

105 rgest genome with the fewest pseudogenes and IS elements suggests that this isolate's lineage is at a

106 All the IS elements that have been identified in this strain are

107 Porphyromonas gingivalis insertion element (IS element) that is capable of transposition within P. g

108 16-kb region, flanked by insertion sequence (IS) elements, that encodes the restriction/modification

109 Despite its numerous repeated sequences and IS elements, the serotype 2 genome has remained remarkab

110 maps of recently active Insertion Sequence (IS) elements, the simplest form of MGEs, for all sequenc

111 By linking the predicted IS elements to various characteristics of the organisms

112 Only one IS element was found in T. litoralis.

113 A total of 23 homologous IS elements was found in the genome sequence of P. furio

114 Eight other ORFs not associated with IS elements were identified and deserve future investiga

115 uence of P. furiosus, whereas no full-length IS elements were identified in the genomes of Pyrococcus

116 Four new IS elements were identified.

117 and require extensive laboratory resources, IS elements were investigated as a means to subtype this

118 rived from a Roseiflexus insertion sequence (IS) element where the resulting transcriptional slippage

119 This is the first genome-scale maps of IS elements with detailed structural information on the

120 . furiosus is flanked by insertion sequence (IS) elements with inverted and direct repeats.

121 restimates reactive Cu, Cr, As, and Mo, that is, elements with a particularly high affinity for organ

122 mutations that introduced stop codons and/or IS elements within the gene or the promoter region in fi