ライフサイエンスコーパス: ISO

1 ISO administration resulted in significant ryanodine rec

2 ISO and PDE3 inhibitors also induced the PDE3A-ICER feed

3 ISO application led to significant RyR phosphorylation a

4 ISO caused reduction in cardiac function with evidence o

5 ISO rats showed significantly enhanced levels of both LT

6 ISO represents novel pharmacotherapy for AILI.

7 ISO successfully mimicked sympathetic stimulation as sho

8 ISO suppression by SIL was prevented in cells pretreated

9 ISO treatment exaggerated ROS generation, p38 MAPK activ

10 ISO+I(TO) decrease-induced CADs were abolished by beta(1

11 ISO, FSK, or DB rapidly increased oxidative and glycolyt

12 ISO-1 and MIF knockout (MIFKO) had greater accumulation

13 ISO-1, like anti-MIF, inhibited the interaction between

14 ISO-induced CADs were significantly suppressed by dynami

15 ISO-induced HDAC5 nuclear export occurred through a beta

16 ISO-induced left ventricular dysfunction and hypertrophi

17 as performed in accordance to the ISO-17025 (ISO/IEC, 2005) and Eurachem guidelines.

18 ion for Standardization (ISO) (ISO/TS 17728, ISO 18593:2004 and ISO 17604:2003) standards.

19 At pHo 7.3, ISO was inhibited by BaCl2 (IC50 465 microM), but unaffe

20 With JNJ-303, ISO decreased APD significantly more in the epicardium a

21 llowing intravenous infusion of either 0.9% (ISO) or 3.0% (HYPER) NaCl saline, 12 subjects were passi

22 cific inhibitor of MIF-tautomerase activity, ISO-1, was investigated in PBMCs.

23 r, nuclear accumulation of HDAC5 under acute ISO/PKA signaling is dependent on phosphorylation of Ser

24 fraction of dead myocytes peaked 1 day after ISO and decreased thereafter.

25 LV function was impaired in rats 1 day after ISO and started to improve at 3 days.

26 fibrosis were also not altered 28 days after ISO injection.

27 r, myocyte apoptosis was not increased after ISO injury.

28 Circulating troponin I levels after ISO were elevated, further documenting myocyte damage.

29 An ISO 6134-compliant generalized least-squares regression

30 housed in a laminar flow cabinet allowing an ISO class-5 environment.

31 urement of NO in the Ussing chamber using an ISO-NO meter) decreased I(sc) partially.

32 53 to 27% for the constant alpha (0.019) and ISO-7888 methods, respectively.

33 tion (ISO) (ISO/TS 17728, ISO 18593:2004 and ISO 17604:2003) standards.

34 n regard to Council Directive 333/2007EC and ISO/IEC 17025 (2005).

35 particulate-controlled cleanrooms (ISO 5 and ISO 8) and two vicinal uncontrolled areas (office, chang

36 AILI activated the CWP, and ISO enhanced Wnt-ligand production.

37 re validated according to CD 2002/657/EC and ISO 17025 guidelines.

38 on: NoiseMaker is written in C#, an ECMA and ISO standard language with compilers for multiple operat

39 Although ET1 and ISO shared a similar ability to induce HDAC5 nuclear exp

40 in vitro, which is important in Ang II- and ISO-induced cardiomyocyte apoptosis.

41 or Ag conjugated to control mAb (ISO*KLH and ISO*Bet v 1).

42 test whether PKA is required for the PC and ISO-induced protection, hearts were treated with the PKA

43 found that PKI and H-89 blocked the PC- and ISO-induced improvement in postischemic LVDP and infarct

44 and K(0.5), respectively), and (3) PDBu and ISO combine to activate NKA in wild-type to the level fo

45 A function in cardiac myocytes, (2) PDBu and ISO effects are additive in the mouse (affecting mainly

46 in level, was similar to that after PDBu and ISO treatment.

47 The K(m) values for succinate in RSO and ISO vesicles were similar, approximately 30 microM.

48 Recombinant Wnt3a and ISO-603B-conditioned media, but not ISO alone, protected

49 increased with SIL+ISO but unaltered by ANP+ISO.

50 ve treatments with either the MIF antagonist ISO-1 or anti-CD74 neutralizing antibodies on the aberra

51 curative treatments with the MIF antagonist ISO-1 or anti-CD74 neutralizing antibodies partially rev

52 rmore, allotransplantation of HPCs from APAP+ISO-treated mice to other APAP-injured mice improved AIL

53 he standard Griess spectrophotometric assay (ISO 2918/1975), proving the suitability of using immobil

54 that of oil-exposed fish (1 mW g(-1) Mv) at ISO concentrations of 1 x 10(-6) M.

55 serve at the same time as fluorescence-based ISOs, and apply it specifically to potassium (K(+)).

56 rated that there was no relationship between ISO quality categories and safranal content using HPLC-D

57 he heart with the inhibitory peptide blocked ISO-mediated BVR activation and augmented apoptosis; con

58 tric acid extraction (0.43 M) was adopted by ISO (ISO-17586:2016) as standard for extraction of geoch

59 Slower activation of I(Ks) than of I(Ca) by ISO may explain why different sympathetic modes, i.e. sy

60 Hepatoprotection by ISO is mediated by para- and autocrine effects of Wnt si

61 ILI raised HPC numbers, further increased by ISO, with attenuation of liver injury.

62 asma free fatty acid (FFA) levels induced by ISO competed with glucose ([(18)F]FDG) uptake in BAT loc

63 nd enhanced beta-AR signaling as measured by ISO-stimulated cAMP production.

64 tic rats, and this increase was prevented by ISO and GPI-15427.

65 amines had low HPC numbers, reconstituted by ISO.

66 ealer properties were tested as specified by ISO 6876 (2012) and also in alternative media.

67 nonselective beta-adrenergic stimulation by ISO at concentrations that increase energy expenditure t

68 es in two particulate-controlled cleanrooms (ISO 5 and ISO 8) and two vicinal uncontrolled areas (off

69 In contrast, continuous ISO perfusion diminished APD prolongation and reduced th

70 In contrast, ISO reduced HDAC5 phosphorylation in the presence or abs

71 s, and we show that the approximately 20-day ISOs in alongshore wind stress dominated the upwelling p

72 dly with age, beginning in the fourth decade ISO 7029 (2000).

73 Pretreatment with ISO or IL-13 decreased ISO-induced cAMP generation compared with ISO for 10 min

74 d administration of NAC did not, but delayed ISO did, reverse AILI.

75 Single- or multiple-dose ISO injury was not associated with an increase in the pe

76 ed a high-risk window of EADs in LQT2 during ISO perfusion owing to mismatch in the time courses of I

77 r, developed at different time points during ISO application.While SR Ca2+ release and load reached a

78 Scavenging ROS during ISO application decreased the occurrence of Ca2+ waves a

79 llowed by a gradual decline over time during ISO application.

80 testing laboratory that complies with BS EN ISO 139:2005+A1:2011.

81 thod was accredited in compliance with PN-EN ISO/IEC 17025:2005 standard and it was operated under fl

82 as a single analyte assay in view of the EN ISO 15189 accreditation procedure.

83 to the accreditation procedure under the EN ISO 15189 standard was carried out for allergen-specific

84 evels of aerosol entering the DC (equivalent ISO class), together with its DRH.

85 ihydro-5-isoxazole acetic acid methyl ester (ISO-1) inhibited huMIF but not MIF of parasitic origin.

86 ihydro-5-isoxazole acetic acid methyl ester (ISO-1), an orally bioavailable MIF antagonist, in two di

87 ihydro-5-isoxazole acetic acid methyl ester (ISO-1).

88 The biodistribution of (18)F-ISO-1 and human dosimetry were evaluated.

89 e of a significant correlation between (18)F-ISO-1 and Ki-67 makes this agent promising for evaluatio

90 cer, or head and neck cancer underwent (18)F-ISO-1 PET.

91 Tumor (18)F-ISO-1 uptake was assessed semiquantitatively by maximum

92 No adverse effects of (18)F-ISO-1 were encountered.

93 18)F-fluoroethox y)-5-methylbenzamide ((18)F-ISO-1), and evaluate the feasibility of imaging tumor pr

94 a membrane fractions retained the 10-15-fold ISO stimulation of GRK site phosphorylation and GRK5 lev

95 the beta2AR (t1/2 = 1 min) with an EC50 for ISO stimulation of approximately 80 nM.

96 nd a weakening variance of its low-frequency ISO (LF-ISO) cycle.

97 Furthermore, ISO injections did not increase new myocytes in cKit(+/C

98 /db myocyte/heart preparations exposed to HG/ISO.

99 nctionally, SGBS adipocytes displayed higher ISO-induced basal leak respiration and overall oxygen co

100 However, ISO response was reversed by beta2-adrenergic receptor (

101 3 (48 hours) or isoproterenol hydrochloride (ISO; 30 minutes) pretreatment were stimulated with ISO (

102 time to the best of our knowledge, identify ISO as a major active compound for the anti-cancer activ

103 rate to the same levels as control cells in ISO.

104 It is written in ISO C and C++, provides language bindings for Common Lis

105 xcitation, with the consequence of increased ISO-W400 distance and diminished tunneling rate by almos

106 Overexpression of Nur77 markedly inhibited ISO-induced cardiac hypertrophy by inducing nuclear tran

107 Moreover, the MIF inhibitor ISO-1 inhibited AML-induced IL8 expression by BM-MSCs as

108 Systemic administration of the MIF inhibitor ISO-1 significantly blocked photoreceptor apoptosis, out

109 nnot be inhibited by the human MIF inhibitor ISO-1.

110 ta show the feasibility of the MIF-inhibitor ISO-1 to block pathological damage responses in retinal

111 growth than the prototypical MIF inhibitor, ISO-1.

112 neutralizing Abs or MIF-specific inhibitor, ISO-1) were only effective in androgen-independent prost

113 Intermittent ISO treatment improved post-ischemic recovery of LVDP (5

114 acid extraction (0.43 M) was adopted by ISO (ISO-17586:2016) as standard for extraction of geochemica

115 onal Organization for Standardization (ISO) (ISO/TS 17728, ISO 18593:2004 and ISO 17604:2003) standar

116 Rats isolated (ISO) from their mother and each other for 1 h daily from

117 Isoprenaline (ISO) prolonged APDs and triggered EADs in LQT1 myocytes

118 the nonselective beta-agonist isoprenaline (ISO) and compared this with cold-activated BAT activity.

119 However, under isoprenaline (ISO), both the application of JNJ-303 and additional E-4

120 beta-AR stimulation with isoprenaline (ISO) increased Ca2+ transient amplitude, ICa-L and SRCa2

121 Isoproterenol (ISO) increased Ca2+ transient amplitude during systole,

122 Isoproterenol (ISO) or PKA activation results in strong nuclear accumul

123 ated with the beta-AR agonist isoproterenol (ISO) (anxA4a(+/+) vs. anxA4a(-/-): 5.1 +/- 0.3 vs. 6.7 +

124 a-adrenergic receptor agonist isoproterenol (ISO) also induced persistent PDE3A down-regulation and c

125 the beta-adrenoceptor agonist isoproterenol (ISO) and by varying afterload pressures.

126 ose (HG) and the beta-agonist isoproterenol (ISO).

127 The beta-adrenergic agonist isoproterenol (ISO; 1 muM) increased [Ca(2+)](SR) well above the contro

128 nked beta-adrenergic agonist, isoproterenol (ISO), but in a transient manner.

129 he beta-adrenoceptor agonist, isoproterenol (ISO), or the beta-adrenoceptor antagonist, propranolol.

130 or a beta-adrenergic agonist, isoproterenol (ISO; 0.2 mg/kg BW) alone or in combination with 500 micr

131 pe and IL-10 knockout mice by isoproterenol (ISO) infusion.

132 beta-adrenergic receptors by isoproterenol (ISO) resulted in an impaired contractile response of TG

133 nergic receptor activation by isoproterenol (ISO).

134 pertrophic stimuli, including isoproterenol (ISO), phenylephrine (PE), and endothelin-1 (ET-1).

135 dult feline heart by infusing isoproterenol (ISO) for 10 days via minipumps, and then animals were al

136 In WT myocytes, 1 micromol/L isoproterenol (ISO) increased PLM phosphorylation and stimulated NKA ac

137 preparations with 1.0 microM isoproterenol (ISO) caused a rapid maximal 10-15-fold increase in GRK s

138 l), treated with 10 nmol/L of isoproterenol (ISO) for 5 min followed by 5 min washout, or preconditio

139 hat chronic administration of isoproterenol (ISO) persistently increases the frequency of mPTP openin

140 were exposed to high doses of isoproterenol (ISO), in vivo and in vitro.

141 gle subcutaneous injection of isoproterenol (ISO; 200 mg/kg) in mice causes acute myocyte death (8%-1

142 L sildenafil (SIL) suppressed isoproterenol (ISO)-stimulated contractility, whereas 10 micromol/L atr

143 cardiac damage responding to isoproterenol (ISO) in adult offspring that underwent maternal inflamma

144 n (CDF) and I(Ca) response to isoproterenol (ISO) were significantly reduced.

145 were examined in response to isoproterenol (ISO), forskolin (FSK), and dibutyryl-cAMP (DB), coupled

146 After pretreatment with isoproterenol (ISO) (1 mumol/L), PDBu still increased the NKA V(max) an

147 alized after stimulation with isoproterenol (ISO) and fully recycled at 4 h upon ISO removal.

148 onic beta-AR stimulation with isoproterenol (ISO) for 48 h reduced Ito,f along with mRNA expression o

149 action after stimulation with isoproterenol (ISO), a beta-adrenergic receptor (betaAR) agonist.

150 ysiological HR increases with isoproterenol (ISO), suggesting that other I(f)-independent pathways ar

151 ut the PARP inhibitors 1,5-isoquinolinediol (ISO; 3 mg kg(-1) d(-1) intraperitoneally) and 10-(4-meth

152 tive of stilbene compound, isorhapontigenin (ISO), was isolated from this Chinese herb.

153 Isoxyl (ISO) and thiacetazone (TAC), two prodrugs once used in t

154 300 mg/kg ISO, or 2 daily doses of 200 mg/kg ISO for 6 days.

155 ngle injections of vehicle, 200 or 300 mg/kg ISO, or 2 daily doses of 200 mg/kg ISO for 6 days.

156 vents, primarily in the break phase of an LF-ISO cycle, reduce the intensity of the following active

157 kening variance of its low-frequency ISO (LF-ISO) cycle.

158 This reduces the LF-ISO intensity and mean ISM rainfall.

159 y of rAceMIF was not inhibited by the ligand ISO-1, which was previously determined to be an inhibito

160 h native Ag or Ag conjugated to control mAb (ISO*KLH and ISO*Bet v 1).

161 In a time- and dose-dependent manner, ISO increases Nur77 expression in the nuclei of cardiomy

162 rsus phosphorylation-independent mechanisms, ISO induced a significantly greater increase in MEF2 act

163 Here we show that CaMKII mediates ISO HR increases by targeting SAN cell Ca(2+) homeostasi

164 this tautomerase activity; a lead molecule, "ISO-1 ((S,R)-3-(4-hydroxyphenyl)-4,5-dihydro-5-isoxazole

165 of the beta-agonist isoproterenol (0.1 mum; ISO), from 0% to 64% (P < 0.05).

166 rat ventricular myocytes and H9c2 myoblasts, ISO activated nuclear factor-kappaB and inhibited signal

167 mzMatch.R and mzMatch-ISO are available free of charge from http://mzmatch.sou

168 Here, we describe mzMatch-ISO, a new extension to the metabolomics analysis pipeli

169 nstrate the power and versatility of mzMatch-ISO by analysing a (13)C-labelled metabolome dataset fro

170 d untargeted isotope profiling using mzMatch-ISO provides a convenient visual summary of the quality

171 nt3a and ISO-603B-conditioned media, but not ISO alone, protected isolated hepatocytes from death, re

172 dy was to validate (SANCO/12495/2011 and NTC-ISO/IEC 17025) multi-residue multi-class methods using Q

173 /beta-catenin pathway (CWP) in the action of ISO on HPC expansion and comparison of ISO with the curr

174 In contrast, administration of ISO along with leptin did not prevent the leptin-induced

175 was decreased by 28% after administration of ISO in TG cardiomyocytes.

176 ting these enzymes may impact the binding of ISO and TAC to the dehydratases.

177 epolarization gradient by the combination of ISO and E-4031.

178 on of ISO on HPC expansion and comparison of ISO with the current standard of care, N-acetylcysteine

179 However, the highest concentration of ISO (1 x 10(-5) M) rescued cardiac function.

180 e fraction caused minimal desensitization of ISO stimulation of adenylyl cyclase activity.

181 A single dose of ISO causes injury in approximately 10% of the cardiomyoc

182 There was no significant effect of ISO on apoptosis and colony formation of cells transfect

183 These different effects of ISO on LQT1 and LQT2 were verified by optical mapping of

184 ardiac dysfunction after chronic infusion of ISO in mice.

185 e Wistar rats received a single injection of ISO (5 mg kg-1) and were sacrificed 1, 3, and 6 days lat

186 Thus, a single injection of ISO causes diffuse myocyte death through Ca2+ leakage se

187 ly increased ROS production after 4-6 min of ISO application.

188 at the highest frequency only after 6 min of ISO application.Measurement of intra-SR-free Ca2+ concen

189 K2 associated with PEBP1 after 10 minutes of ISO in association with low phosphorylated GRK2 (pGRK2)

190 e of D396 determine the preferred pathway of ISO* relaxation.

191 the same cells, excluding the possibility of ISO regulating XIAP expression at the level of protein d

192 present study, we examined the potential of ISO in anti-cancer activity and the mechanisms involved

193 was subsequently lowered in the presence of ISO (by lowering [Ca(2+)](o) to 1 mM and partially inhib

194 from PBMCs was attenuated in the presence of ISO-1.

195 comparable to that for WT in the presence of ISO.

196 ne signaling mechanism distinct from that of ISO, involving G(i)-coupled betagamma subunits of hetero

197 We found that 2 weeks of ISO treatment in adult offspring of LPS-treated mothers

198 ime scale and show the leading importance of ISOs in driving this coastal upwelling ecosystem during

199 Based on ISO criteria only one egg kit accurately determined egg

200 Ion-selective optodes (ISOs), the optical analog of ion-selective electrodes, h

201 r inhibiting Drp1 activity blocks CaMKII- or ISO-induced mPTP opening and myocyte death in vitro and

202 tion, knockdown of caveolin-1 expression, or ISO stimulation.

203 ted in International Standards Organization (ISO) and other international or regional standards.

204 s quasi-rhythmic intraseasonal oscillations (ISO) manifested as alternate 'active' phases of copious

205 pically exhibits intraseasonal oscillations (ISOs) with periods from approximately 15 to 40 days, as

206 , using right-side-out (RSO) and inside-out (ISO) membrane vesicles.

207 Conversely, after pretreatment with PDBu, ISO further increased the Na(+) affinity of NKA and phos

208 In contrast, in the presence of IL-13 plus ISO (10 minutes), binding of GRK2 to PEBP1 decreased, wh

209 ss ISOs resulted from north-south positional ISOs of the atmospheric jet stream (JS).

210 The peak LV developed pressure/ISO dose response was shifted rightward 100-fold in SHR

211 CaMKII inhibition prevents ISO effects on SAN Ca(2+) uptake and release from intrac

212 0-fold more active than the well-studied (R)-ISO-1 and more than 200-fold more active than the chrome

213 15LO1 knockdown restored ISO-induced cAMP generation.

214 ion and not only inhibited but also reversed ISO-induced cardiac remodeling.

215 ue-light excitation, the isoalloxazine ring (ISO) may undergo an ultrafast reduction by a nearby tryp

216 ) displayed the opposite: increased with SIL+ISO but unaltered by ANP+ISO.

217 gly, myocardial cGMP changed little with SIL+ISO yet rose nearly 5-fold with ANP, whereas protein kin

218 Single ISO injections also caused membrane injury in approximat

219 ltered diastolic function 1 day after single ISO injection.

220 nse mutation in the hadA gene of spontaneous ISO- and TAC-resistant mutants was sufficient to confer

221 re also found in M. tuberculosis spontaneous ISO- and TAC-resistant mutants.

222 Growth rate inhibition occurred in standard ISO tests (EC50 values of 15-200 mg Pt/L), but also in a

223 , align with the international AST standard (ISO 200776-1; 2006) and could be used for rapid determin

224 current International Organization Standard (ISO/DIS 15197) requirements.

225 ernational Organization for Standardization (ISO) (ISO/TS 17728, ISO 18593:2004 and ISO 17604:2003) s

226 ernational Organization for Standardization (ISO) International Workshop Agreement on tiered cookstov

227 ernational Organization for Standardization (ISO) protocols.

228 Such wind stress ISOs are typical along Oregon in the summer upwelling se

229 These wind stress ISOs resulted from north-south positional ISOs of the at

230 Interestingly, IL-10 suppressed ISO-induced nuclear factor-kappaB activation and attenua

231 Factors to convert HS values, for the target ISO and GDC components, into theoretical EO values were

232 2O, P </= 0.01), which remained greater than ISO throughout heating.

233 We found that ISO exhibited significant inhibitory effects on human bl

234 We also identified that ISO down-regulated XIAP gene transcription via inhibitio

235 Further voltage-clamp studies revealed that ISO increases L-type calcium current (I(Ca)) faster than

236 Further studies have shown that ISO down-regulation of XIAP protein expression was only

237 These studies suggest that ISO injury activates cardiac progenitor cells that can d

238 mapping of the whole heart, suggesting that ISO-induced EADs are genotype specific.

239 The ISO method for calculating wind driven rain loads is ada

240 The ISO-standardized RHIZOtest is used here for the first ti

241 oxide dismutase mimetic MnTBPA abolished the ISO-mediated ROS production.

242 In addition, the ISO-stimulated phosphorylation of phospholamban at Ser(1

243 fore, this approach could be included in the ISO 3632 method (2011).

244 ckers of betaAR-1 and betaAR-2 inhibited the ISO response in Pkd2(+/-) mice, suggesting that the deph

245 more, we discovered that when KCC2 lacks the ISO domain, it still retains swelling-activated transpor

246 The aim of this work was a comparison of the ISO 3632 (2011) method and an HPLC-DAD method for safran

247 A re-evaluation of the ISO standard for bottom sediment sampling is recommended

248 ve STAT3 mimicked the IL-10 responses on the ISO effects, confirming that the IL-10-mediated inhibiti

249 CaMKII inhibition has no effect on the ISO response in SAN cells when SR Ca(2+) release is disa

250 Ideltac nor CaMKIIdeltab did not prevent the ISO-mediated Ito,f reductions, even though CaMKIIdeltac

251 JTV519, a RyR2 stabilizer, prevented the ISO-induced death of adult myocytes in vitro.

252 in, rotenone, also effectively prevented the ISO-mediated ROS production.

253 ast, NF-kappaB inhibition partly rescued the ISO-mediated Ito,f reductions in association with restor

254 f the C terminus, unique to KCC2 (termed the ISO domain), is required for KCC2 to cotransport K(+) an

255 This finding indicates that the ISO domain is required for neuronal Cl(-) regulation.

256 NA and KChIP2 promoter data suggest that the ISO-induced Ito,f reductions are, in part, mediated thro

257 absorbance values measured according to the ISO Normative 3632-1:2011 method.

258 adopted for quality grading according to the ISO Normative 3632.

259 he method was performed in accordance to the ISO-17025 (ISO/IEC, 2005) and Eurachem guidelines.

260 ctivation participate in the response to the ISO-induced myocardial injury.

261 fold from the uncontrolled areas towards the ISO 5 cleanroom, accompanied with a reduction of the liv

262 scale as well, and these correlated with the ISOs in alongshore wind stress and JS position, even tho

263 origins were analysed by UV-vis according to ISO 3632 (2011) and by HPLC-DAD.

264 amples with the highest quality according to ISO 3632 specifications produced a typical spectrum prof

265 Aqueous extracts prepared according to ISO 3632-2 were then examined by tristimulus colorimetry

266 both procedures were evaluated according to ISO 9909 and GDC standards for sage EO quality, revealin

267 of the respective laboratories conforming to ISO/IEC 17025:2005 standard techniques.

268 D showed the greatest lusitropic response to ISO (P<0.05) and offset the pacing-induced increase in L

269 uction at the basal level and in response to ISO stimulation.

270 d OCR and uncoupling capacity in response to ISO.

271 DIM adipocytes, but had lower sensitivity to ISO-stimulated lipolysis and reduced triglyceride conten

272 of RyR2, which may explain their survival to ISO insult.

273 ease in the resistance of M. tuberculosis to ISO and TAC, respectively.

274 nhancing electron transfer (ET) from W400 to ISO*.

275 and fibroblast lines were established under ISO class 5 cGMP conditions.

276 5F and 3R4F research cigarettes smoked under ISO (Cambridge Filter or FTC) and Intense (Health Canada

277 with a chimeric KCC2 that lacked the unique ISO domain, hyperpolarizing responses to GABA were aboli

278 terenol (ISO) and fully recycled at 4 h upon ISO removal.

279 In vitro, ISO-induced proliferation of 603B cells was CWP dependen

280 from a rabbit model of heart failure, where ISO-induced nuclear import is ablated, but G(q)-agonist

281 ed ISO-induced cAMP generation compared with ISO for 10 minutes alone paralleled by increases in beta

282 All sealers complied with ISO specifications.

283 eviation (s( *)), were assigned in line with ISO 13528.

284 euronal networks in a consistent method with ISO 10993-5 guidance.

285 Treatment of myocytes with ISO for 15 min significantly reduced the free thiol cont

286 rmal microdialysis probes, one perfused with ISO saline and the other with HYPER saline.

287 Pretreatment with ISO or IL-13 decreased ISO-induced cAMP generation compa

288 0 minutes) pretreatment were stimulated with ISO (10 minutes).

289 e we show that treating M. tuberculosis with ISO or TAC results in both cases in the accumulation of

290 In DU-145 xenografts, ISO-1 significantly decreased tumor volume and tumor ang

291 Z-ISO evolved from an ancestor related to the NnrU (for ni

292 Z-ISO was found to be important for both light-exposed and

293 gracilis, which is similarly required for Z-ISO activity.

294 improving nutritional content) argued for Z-ISO as a pathway requirement.

295 arative genomics illuminated the origin of Z-ISO found throughout higher and lower plants, algae, dia

296 To prove the existence of Z-ISO, maize (Zea mays) and Arabidopsis (Arabidopsis thali

297 This step, mediated by a putative Z-ISO, was predicted to occur in the sequence of redox rea

298 activity upstream of CRTISO, which we term Z-ISO, an activity that catalyzes the cis- to trans-conver

299 volutionarily distant plants, suggest that Z-ISO activity is not unique to maize, but will be found i

300 ,15,9'-tri-cis-zeta-carotene, proving that Z-ISO encoded the missing step.