コーパス検索結果 (left1)
通し番号をクリックするとPubMedの該当ページを表示します
1 IgG AHAs cloned from a single human donor exhibited rest
2 IgG antibodies to a novel antigen were elevated in offsp
3 IgG from patients with anti-C3b Abs stabilized C3bBb and
4 IgG MFI was analyzed after elimination of prozone effect
5 IgG titers against glycoprotein (gp) 70V1V2 92TH023 incr
6 IgG transfer in IgG-deficient mice implicated IgG as the
8 of strikingly different affinities, these 3 IgG subclasses have been shown to enable induction of sy
10 rare in-frame deletion in FCGR2B abolishing IgG binding to the encoded receptor (p.Asn106del: P = 4.
11 ethod to identify and quantify low-abundance IgG N-glycans and show some of these IgGs can be used as
13 10-35) of 45 in the placebo group; adjusted IgG seroresponses were seen in 46 (98%, 89-100) of 47 in
16 mouse strain in which the human low-affinity IgG receptor locus, comprising both activating (hFcgamma
17 d degranulation of eosinophils on aggregated IgG via increased production and activation of both CD32
18 was true when the autologous and allogeneic IgG concentrations were augmented in allograft recipient
19 nto lamellar nanostructures with alternating IgG and poly(N-isopropylacrylamide) (PNIPAM) nanodomains
20 on in 2015, was 0.024%, equaling amphiphysin IgG (0.026%) and more common than ANNA-2 (also known as
23 liferation, plasmablast differentiation, and IgG secretion from circulating CD27(+) memory and memory
25 ts with delayed meat allergy display IgE and IgG Ab that selectively recognize the alpha-gal epitope
27 s were made in parallel to elucidate IgE and IgG reactivity, and putative function analyses were perf
31 Additionally, both HCMV specific IgM and IgG B-cell responses with the ability to neutralize viru
32 provide evidence that although both IgM and IgG BCRs reside in highly heterogeneous protein islands
33 ide association studies for anti-PEG IgM and IgG responses in Han Chinese with 177 and 140 individual
35 ls, defined as positive for anti-PEG IgM and IgG responses, respectively, and with 492 subjects witho
39 es, reduces total immunoglobulin M (IgM) and IgG levels, and leads to increased proliferation and upr
40 gradual increase of all immunoglobulins and IgG subclasses, but values were always significantly low
41 antigen were specific to ZIKV infection, and IgG avidity revealed recent ZIKV infection and past DENV
42 both IgM (for anti-ATG and anti-Neu5Gc) and IgG (for anti-ATG, -Gal, and -Neu5Gc), peaking at 1 mont
43 ent increased the titers of neutralizing and IgG antibodies against both challenge viruses compared w
45 developed antibodies and T cells to PAD and IgG antibodies to citrullinated fibrinogen peptides, in
46 , we explored the diversity of protease- and IgG subclass-restricted AHAs and their potential as immu
47 cits significant increases in OPA titers and IgG concentrations that persist 2 years postvaccination
48 nts of IgA-TTG and total IgA, or IgA-TTG and IgG against deamidated gliadin (IgG-DGL) could identify
53 or complement activation, reduced antiviral IgG responses to the same extent as observed in mus(-/-)
55 Inclusion criteria were as follows: (1) AQP4-IgG seropositivity, (2) myelitis attack and (3) MRI spin
56 condary antibody labeling of monoclonal AQP4-IgGs with differing epitope specificity bound to isolate
57 nt; 5C8H1 (5/5) more consistently attenuated IgG alloAb production compared to 2C10R4 (4/6) and IDEC-
62 T cell responses, similar levels of binding IgG antibodies, low levels of IgA antibodies, and high l
64 technology platform of generating bispecific IgG antibodies, "Bispecific Antibody by Protein Trans-sp
65 series of monovalent and bivalent bispecific IgGs composed of the anti-HER2 trastuzumab moiety paired
66 herapy results in the production of blocking IgG/IgG4 antibodies that can inhibit IgE-dependent activ
67 the induction of allergen-specific blocking IgG in outbred guinea pigs which had been immunized with
70 A mutant strain is predominantly mediated by IgG antibodies binding to antigens expressed exclusively
76 (0.33nmol/l, range = 0.02-5.14) than CASPR2-IgG-positive specimens (0.10nmol/l, range = 0.00-0.45, p
77 on is as follows: CD4(+) T cells/ILC2 cells, IgG, and FcRgamma>mast cells>IgE and FcepsilonRI>basophi
79 s had higher voltage-gated potassium channel-IgG immunoprecipitation values (0.33nmol/l, range = 0.02
81 r binding (CMV tet(high) CTLs) in 53/115 CMV IgG(+) patients stem cell transplanted from CMV IgG(+) d
85 er of maternal IgG and OVA immune complexes (IgG-IC) via breast milk and induction of allergen-specif
86 d transfer and uptake of allergen-containing IgG immune complexes (Ig-ICs) by gut dendritic cells (DC
88 ollapsin response-mediated protein 5 (CRMP5) IgG (26%) or antineuronal nuclear antibody type 1 (ANNA-
89 e thermodynamic conditions for crystallizing IgG antibodies in the solution environments of interest.
90 had a combination of proximal tubule damage, IgG-positive immune deposits in the tubular basement mem
91 bated with alpha-gal or protein G to deplete IgG Ab. alpha-Gal-specific IgG1-4 Ab in individuals with
92 control of nonspecific human IgG (89)Zr-DFO-IgG in U87MG tumors was 11.5 +/- 3.3 %ID/g, demonstratin
94 work is needed to define the role different IgG subtypes play in regulating the iatrogenic disease.
99 ntial distribution mechanisms for endogenous IgG, which is one of the most abundant proteins in the C
100 -ICLC increased the low-level serum anti-Env IgG responses elicited by NYVAC-KC priming significantly
101 Patients negative for anti-C3b and anti-FB IgG had much lower rates of infection (17 [25%] patients
104 reflect events documented in vitro following IgG interaction with AQP4: AQP4 internalization, attenua
106 er antigens already validated as targets for IgG suggest a wide potential for development of a novel
107 l clinically defined cohorts were tested for IgG radioimmunoprecipitation of radioiodinated alpha-den
110 or both Chlamydia-specific immunoglobulin G (IgG) and polymorphonuclear neutrophils and show the impo
112 immunoglobulin M (IgM) and immunoglobulin G (IgG) ELISAs combined can detect ZIKV infection with a se
114 gammaRs), the Fc domain of immunoglobulin G (IgG) mediates a wide spectrum of immunological functions
115 D) ordered arrays of human immunoglobulin G (IgG) were fabricated using well-defined full-length anti
118 nding site and provide new insights into GB1:IgG complex structure that amend and revise the current
122 IgA-TTG and IgG against deamidated gliadin (IgG-DGL) could identify patients with and without celiac
123 rotocol, native heterogeneously glycosylated IgG N-glycans are first deglycosylated with a wild-type
124 the cross-linked Env group developed higher IgG responses against a linear epitope in the gp120 C1 r
125 ge by converting a promiscuous natural human IgG-binding domain, the hyperthermophilic variant of pro
126 1.3 %ID/g and a control of nonspecific human IgG (89)Zr-DFO-IgG in U87MG tumors was 11.5 +/- 3.3 %ID/
127 ysins can be fused to the Fc region of human IgG, creating a fully functional homodimer (or "lysibody
130 cated 5 known variants associating with IgA, IgG or IgM levels or with composite immunoglobulin trait
133 rgens, hydrolase activity and detectable IgE/IgG reactivity are strongly correlated, while no protein
136 significant decrease of all immunoglobulins, IgG subclasses and pneumococcal polysaccharide antibodie
137 gG transfer in IgG-deficient mice implicated IgG as the pathogenetic ligand for endothelial FcgammaRI
139 dy observed sparse lymphocytic infiltrate in IgG-treated tumors and increased inflammatory cell infil
140 ealthy subjects caused insulin resistance in IgG-deficient mice via FcgammaRIIB, indicating that simi
147 anti-insulin antibody in the presence of its IgG isotype.Efficient detection of single molecules is v
148 cular access and distribution of full-length IgG could be enhanced by intrathecal co-infusion of hype
149 resulted in 30% of human samples having less IgG and IgM RBC xenoreactivity than alloreactivity.
151 pectrum and longitudinal outcome in 256 LGI1-IgG-seropositive and/or CASPR2-IgG-seropositive patients
152 testing, detecting only 24 of 38 (63%) LGI1-IgG-positive and 5 of 6 (83%) CASPR2-IgG-positive patien
153 poral hyperintensity was more common in LGI1-IgG-positive (41%) than in CASPR2-IgG-positive patients
156 s system (PNS) manifestations, 39% were LGI1-IgG seropositive (7% had solely neuropathy or pain).
159 an immunological perspective in maintaining IgG populations, FcRn can contribute to the pathogenesis
160 n and developed fewer spleen and bone marrow IgG plasma cells and memory B cells, compared with contr
162 ceptor (FcRn)-dependent transfer of maternal IgG and OVA immune complexes (IgG-IC) via breast milk an
164 t the 2 x 10(7) PFU dose, the geometric mean IgG ELISA endpoint titre was 1624 (95% CI 1146-2302) and
165 resumptive pulmonary tuberculosis to measure IgG antibody responses to 57 M. tuberculosis antigens us
168 ndrocyte glycoprotein immunoglobulin G1 (MOG-IgG) and associated clinical features of patients from a
170 so investigate the clinical relevance of MOG-IgG through a longitudinal analysis of serological statu
174 36 patients with BP without anti-BP180 NC16A IgG reactivity underwent evaluation of the diagnostic im
176 hat initial high viral load and neutralizing IgG response may function in a seemingly contrasting man
178 enous immunoglobulin (IVIG), a pooled normal IgG formulation prepared from thousands of healthy donor
181 ratio of absorbance of ZIKV-NS1 to DENV1-NS1 IgG ELISA can distinguish ZIKV with previous DENV and se
184 yeloid cells and its differential binding of IgG subclasses controls the contributions of mast cells,
185 dic pH, prevents the simultaneous binding of IgG, and reduces circulating IgG levels in preclinical a
190 In systemic lupus erythematosus, deposits of IgG-immune complexes and the activation of complement in
192 h CSU exhibit significantly higher levels of IgG antithyroid AAbs (strong evidence) and IgE-anti-TPO
194 rong link between CSU and elevated levels of IgG antithyroid autoantibodies (AAbs), with most of a la
196 nitiating the pathophysiological outcomes of IgG binding to astrocytic AQP4 are poorly understood.
197 served (r = 0.481; P = .31), the presence of IgG anti-BP180 NC16A antibodies was associated with the
200 IgG subtypes and (iii) assess reactivity of IgG antibodies against proteins modified to different le
203 is required to explore the potential use of IgG FXa reactivity as a novel biomarker to stratify trea
205 plays a critical role in the trafficking of IgGs across tissue barriers and in retaining high circul
206 e the authors conduct a multivariate GWAS on IgG N-glycosylation phenotypes and identify 5 novel loci
208 o His6-OPH in vivo as determined by anti-OPH IgG and cytokines formation in Sprague Dawley rats and B
211 s already been successfully applied to other IgG-based therapeutics, substantially improving their cl
213 ison of experimentally mapped Der f 1/Der p1 IgG epitopes to the same surface patch on Blo t 1, as we
214 ialylation was highly specific to pathogenic IgG at the site of inflammation, driven by local platele
221 to increase the average mass of proteolytic IgG peptides (>/=4.5 kDa) and produce peptides which uni
223 travenous immunoglobulin (IVIG) are purified IgG preparations made from the pooled plasma from thousa
226 jection, and immunohistochemistry for rabbit IgG and THSD7A as well as ultrastructural analyses showe
228 ice and rabbits, MBC4 induced cross-reactive IgG antibodies, which were able to block the binding of
229 lar Ca(2+) release in HUVEC and FXa reactive IgG from patients with APS and/or SLE potentiate this ef
230 vation and investigated whether FXa reactive IgG from patients with APS or SLE/APS- alter these respo
234 In conclusion, AHAs specifically recognize IgG subclass- and protease-restricted hinge neoepitopes.
235 id precursor N-acetyl-D-mannosamine restored IgG sialylation and preserved insulin sensitivity withou
236 produced V-gene-matched recombinant anti-RhD IgG Abs of the four different subclasses (IgG1-4) with a
237 o developed CL presented higher anti-rLinB13 IgG responses, before the appearance of clinical symptom
238 but not controls, were stimulated to secrete IgG and increase CD27 expression when cultured with solu
239 r1g in non-B cells, we transferred anti-self-IgG (rheumatoid factor) B cells and their physiologic ta
241 duced detectable Dengue cross-reactive serum IgG responses that significantly amplified after Dengue-
242 y 10-fold higher CT B subunit-specific serum IgG response in IgA(-/-) mice after CT immunization was
245 hese findings suggest that allergen-specific IgG antibodies can act to induce and sustain immunologic
246 els have demonstrated that allergen-specific IgG confers sensitivity to systemic anaphylaxis that rel
248 ked differences between regions and specific IgG (>/=0.5 ISU) was present in most subjects everywhere
249 l animals exhibited mucosal antigen-specific IgG and IgA with the IgA responses 30-fold greater than
250 l responses, (ii) characterize drug-specific IgG subtypes and (iii) assess reactivity of IgG antibodi
251 ectable HAI-antibodies but high flu-specific IgG-antibody titers mounted rapid functional antibodies
253 gG Ab nor the addition of alpha-gal-specific IgG Ab from nonallergic individuals changed the IgE reco
254 e depletion of autologous alpha-gal-specific IgG Ab nor the addition of alpha-gal-specific IgG Ab fro
255 nogenic in humans and causes glycan-specific IgG and also IgE responses with clinical relevance.
258 munization schemes that induce Pn3P-specific IgG responses in a carbohydrate-specific T cell-dependen
259 e magnitudes of the gp120- and V1V2-specific IgG responses were comparable between adults and infants
260 potentially protective maternal V3-specific IgG antibodies associated with reduced peripartum HIV tr
262 ificant correlation between antigen-specific IgGs for longevity but not for magnitude and avidity.
263 th 10-fold lower titers and antigen-specific IgGs, (anti-HBs, anti-HBc), consistent with partial immu
268 d N-glycan substrates, 3-4 d to engineer the IgG N-glycosylation, and 2-5 d to synthesize the small-m
271 ses of both the magnitude and avidity of the IgG binding response than those with Env protein alone.
272 ed to assess the biological relevance of the IgG microheterogeneities thus providing valuable informa
277 for the generation of bispecific therapeutic IgGs of which several have progressed into the clinic.
278 undance IgG N-glycans and show some of these IgGs can be used as biomarkers for rheumatoid arthritis.
279 L/6 mice with CPS-CRM197 produced high-titer IgG and opsonizing antibody responses against the CPS co
280 ation with Hcp1 and TssM produced high-titer IgG and robust gamma interferon-secreting T cell respons
281 ctive mechanism derives from FcRn binding to IgG in the weakly acidic environment contained within en
285 ctors underlying differential sensitivity to IgG-mediated arthritis in 2 mast cell-deficient murine l
287 esults revealed that the titers of the total IgG and subtype IgG1 anti-SjHSP60 antibodies were positi
288 ing of the Ig subclass showed that the total IgG response switched from an IgG1 response to an IgG3 r
290 -magnitude, potentially protective anti-V1V2 IgG responses than in adult vaccinees receiving the mode
292 mmaRIIIA binding, in vitro ADCC, and in vivo IgG-mediated cellular depletion, regardless of sialylati
293 uoresceinated secondary Ab (2nd-Ab), whereas IgG subclasses are monitored with Fc-specific monoclonal
294 matopoietic and parenchymal cells, whereupon IgG is diverted from degradation in lysosomes and is rec
296 aled that LRP2 specifically colocalized with IgG in the tubular immune deposits on the ABBA biopsy sp
297 th biclonal gammopathy multiple myeloma with IgG or IgA MGUS clones were subsequently identified from
300 zed mothers or maternal supplementation with IgG-IC was sufficient to induce neonatal tolerance.
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。