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1 omoter after TNFalpha stimulation along with IkappaB kinase alpha.
2 complex, NF-kappaB-inducing kinase-dependent IkappaB kinase-alpha activation, and p52/RelB nuclear tr
3 ed Akt phosphorylation and the expression of IkappaB kinase alpha and beta (IKKalpha and beta) at bot
4 gulate the function of IkappaBalpha, such as IkappaB kinase alpha and beta and NF-kappaB-inducing kin
5  Breast milk appeared to suppress intestinal IkappaB kinase alpha and beta, resulting in inactivation
6 ngs point to constitutive phosphorylation of IkappaB kinase alpha and subsequent alterations in FANCD
7                                              IkappaB kinase-alpha and -beta (IKK-alpha and IKK-beta),
8 gnaling pathways in mice with disruptions in IkappaB-kinase-alpha and IkappaB kinase-beta in the inte
9  molecule to independently bind TRAF6, TAK1, IkappaB kinase alpha, and IkappaB kinase beta.
10  by dominant negative mutants of TRAF2, NIK, IkappaB kinase alpha, and IkappaB kinase beta.
11 inases PCTAIRE-1 (PCTK1), PFTAIRE-1 (PFTK1), IkappaB kinase alpha, and MAP4K4/NIK.
12 ished downstream mediators of NIK signaling, IkappaB kinase alpha/beta (IKKalpha/beta) and NF-kappaB,
13 -regulated kinases (ERK; Thr(202)/Tyr(204)), IkappaB kinase alpha/beta (IKKalpha/beta; Ser(176)/(180)
14 nhibition of TGFbeta-associated kinase-1 and IkappaB kinase alpha/beta activities and reduced express
15  nuclear factor kappaB via downregulation of IkappaB kinase alpha/beta activity.
16 s associated with reductions in sMLA-induced IkappaB kinase alpha/beta and IFN regulatory factor 3 ac
17 1 significantly increased phosphorylation of IkappaB kinase alpha/beta and IkappaBalpha resulting in
18 appaB activation are mediated by a TRAF2-NIK-IkappaB kinase alpha/beta signaling cascade but is MEKK1
19  by a TRAF2-MEKK1-MKK4 but not the TRAF2-NIK/IkappaB kinase alpha/beta signaling pathway.
20 d by increased abundance of RelB and phospho-IkappaB kinase alpha/beta, an indirect activator of NF-k
21 d kinase 1/2, Jun N-terminal protein kinase, IkappaB kinase alpha/beta, and Akt were unaltered, const
22  (phospho-nuclear factor-kappaB p65, phospho-IkappaB kinase alpha/beta, interleukin 1beta, and tumor
23 glycerophosphoinositol-dependent decrease in IkappaB kinase alpha/beta, p38, JNK, and Erk1/2 kinase p
24 ukin 1 receptor-associated kinase (IRAK) and IkappaB kinase-alpha/beta.
25   Of several kinases examined, inhibition of IkappaB kinase alpha blocked STG28-mediated cytoplasmic
26                   Subsequently, induction of IkappaB kinase-alpha by DeltaNp63alpha initiates epiderm
27 1beta), as well as activation of the kinases IkappaB kinase alpha, IkappaB kinase beta, p38, Akt, and
28 uently, others have identified two proteins, IkappaB kinase alpha (IKK-alpha) and IkappaB kinase beta
29                                              IkappaB kinase-alpha (IKK-alpha) and Mitogen- and Stress
30                                              IkappaB kinase-alpha (IKK-alpha) exhibits protein-kinase
31 t genome-wide siRNA screen demonstrated that IkappaB kinase-alpha (IKK-alpha) is a crucial host facto
32 ction of NF-kappaB-inducing kinase (NIK) and IkappaB kinase-alpha (IKK-alpha).
33  through inhibitor of nuclear factor-kappaB (IkappaB) kinase-alpha (IKK-alpha), a protein kinase that
34                                              IkappaB kinase alpha (IKKalpha) activity is required for
35  fashion, associated with phosphorylation of IkappaB kinase alpha (IKKalpha) and degradation of Ikapp
36                We identified the two kinases IkappaB kinase alpha (IKKalpha) and IkappaB kinase beta
37                Two subunits of this complex, IkappaB kinase alpha (IKKalpha) and IkappaB kinase beta
38 nt insolubilization of the upstream kinases, IkappaB kinase alpha (IKKalpha) and IkappaB kinase beta,
39 tion of NF-kappaB requires calcium-dependent IkappaB kinase alpha (IKKalpha) and IKKbeta activation a
40             In NF-kappaB signaling cascades, IkappaB kinase alpha (IKKalpha) and IKKbeta are key mole
41 d NEMO-binding domain from the C terminus of IkappaB kinase alpha (IKKalpha) and IKKbeta can disrupt
42                      Despite their homology, IkappaB kinase alpha (IKKalpha) and IKKbeta have diverge
43                         Two related kinases, IkappaB kinase alpha (IKKalpha) and IKKbeta, phosphoryla
44 tes the recently identified cellular kinases IkappaB kinase alpha (IKKalpha) and IKKbeta, which norma
45 gers activation of cellular protein kinases, IkappaB kinase alpha (IKKalpha) and IKKbeta, which phosp
46   We reported recently a marked reduction in IkappaB kinase alpha (IKKalpha) expression in a large pr
47                  We investigated the role of IkappaB kinase alpha (IKKalpha) in pancreatic homeostasi
48                          Here we report that IkappaB kinase alpha (IKKalpha) is a critical negative r
49                                              IkappaB kinase alpha (IKKalpha) is part of the cytoplasm
50 AA/AA) "knockin" mice in which activation of IkappaB kinase alpha (IKKalpha) is prevented by replacem
51 of NF-kappaB activation, we demonstrate that IkappaB kinase alpha (IKKalpha) is recruited to chromati
52 as independent of NIK's known function as an IkappaB kinase alpha (IKKalpha) kinase, because mice car
53 B essential modifier-binding domain (NBD) of IkappaB kinase alpha (IKKalpha) or IKKbeta to prevent ni
54                  We previously reported that IkappaB kinase alpha (IKKalpha), a component of the kina
55                     We identified a role for IkappaB kinase alpha (IKKalpha), activated by receptor a
56 ion of inhibitor kappaBalpha (IkappaBalpha), IkappaB kinase alpha (IKKalpha), and IkappaB kinase beta
57 asal epidermal keratinocytes require nuclear IkappaB kinase alpha (IKKalpha), but not its protein kin
58 ways of NF-kappaB activation, including p65, IkappaB kinase alpha (IKKalpha), IkappaB kinase beta (IK
59    We previously showed elevated activity of IkappaB kinase alpha (IKKalpha), IKKbeta, and protein ki
60                                              IkappaB kinase alpha (IKKalpha), one of the two catalyti
61 cing kinase (NIK) and its downstream kinase, IkappaB kinase alpha (IKKalpha), which requires the E3 l
62 by producing lymphotoxin, which activates an IkappaB kinase alpha (IKKalpha)-BMI1 module in prostate
63 cing kinase (NIK) and its downstream kinase, IkappaB kinase alpha (IKKalpha).
64 ppaB activation with a constitutively active IkappaB kinase alpha (IKKalpha).
65 Coexpression of dominant-negative mutants of IkappaB kinase alpha (IKKalpha)/IKK1 or IKKbeta/IKK2 als
66                                              IkappaB kinase-alpha (IKKalpha) is required for splenic
67 nes encoding IFN regulatory factor 6 (IRF6), IkappaB kinase-alpha (IKKalpha), and stratifin (SFN) exh
68  Here, we show that the NF-kappaB activator, IkappaB kinase-alpha (IKKalpha), but not IKKbeta, promot
69 ced the complete degradation of both BTK and IkappaB kinase alpha in MCL lines and CD40-dependent B c
70 ctivation of Akt(Thr-308), Akt(Ser-473), and IkappaB kinase alpha kinase.
71 xpression of either dominant-negative AKT or IkappaB kinase alpha mutant, IKKalphaT23A, containing a
72 linositol-3-OH kinase/protein kinase B (AKT)/IkappaB-kinase alpha/NF-kappaB signaling cascade.
73              miR-148a is an inhibitor of the IkappaB kinase alpha/NUMB/NOTCH pathway and an inducer o
74 sed differentiated phenotype and mediated by IkappaB kinase alpha/NUMB/NOTCH signaling.
75 B essential modifier-binding domain (NBD) of IkappaB kinase alpha or IkappaB kinase beta specifically
76 ducing kinase or IkappaB kinase-beta but not IkappaB kinase-alpha significantly inhibited the TWEAK-i
77 tivity was required for maintaining a stable IkappaB kinase alpha subunit (IKKalpha) level because tr
78                           Phosphorylation of IkappaB kinase alpha was observed within 30 minutes, whi
79 trovirally transduced with dominant negative IkappaB kinase alpha, we demonstrate that CXCL12 express

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