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1  tend to prefer playing new violins over Old Italians.
2             We replicated the association in Italians (409 cases, 723 controls), identifying a protec
3                     This report refers to an Italian 69 year old woman with neurofibromatosis type 2
4 tly, analyzing the last name distribution of Italian academics has raised the suspicion of nepotism,
5 system is geographically well-mixed, whereas Italian academics tend to work in their native region.
6              The environmental impact of 153 Italian adults (51 omnivores, 51 ovo-lacto-vegetarians,
7                                              Italian Agency of Drug Evaluation, Istituto Giannina Gas
8  identifies recent artwork restoration using Italian alabaster and provides a robust geochemical fram
9 om the 3 countries separately, including 624 Italians; all patients were treated with percutaneous co
10  individuals from populations of the Eastern Italian Alps - putatively in genetic continuity with the
11 racked roe deer (Capreolus capreolus) in the Italian Alps between 2005 and 2008.
12 in a floristically rich area in the northern Italian Alps were examined by using the rbcL and trnH-ps
13 ee siblings, born to asymptomatic parents of Italian-American descent, who each presented with atypic
14 luding homozygous c.321+1G>T in a subject of Italian ancestry and homozygous c.322-10G>A in affected
15 3 polymorphisms of NOD2 and 1 of NOD1 in 368 Italian and 387 Spanish patients, compared with 368 and
16 l Distress Scale-Revised was translated into Italian and administered along with a measure of depress
17 ality of 10 buckwheat honeys, collected from Italian and est European beekeepers declaring to produce
18  specific questionnaire in English, Spanish, Italian and German was emailed to wound care organisatio
19 st levels of common ancestry are seen in the Italian and Iberian peninsulas, which may indicate diffe
20 d long-term isolation and bottlenecks in the Italian and Iberian populations following their divergen
21                                          The Italian and Iberian populations have low genetic variabi
22     In this study extra virgin olive oils of Italian and non-Italian origin (from Spain, Tunisia and
23 aresthesia, and dyspnea were translated into Italian and rephrased.
24 ith watering, Noisette) were used in French, Italian and USA cellars.
25 ere suitable in discriminating between "100% Italian" and "non-100% Italian" oils.
26  UM, 124 (59.3%) were male, 114 (54.5%) were Italian, and 95 (45.5%) were German; the mean (range) ag
27 domain containing 2 (UBAC2) gene in Turkish, Italian, and Chinese populations.
28 osis graded and staged according to Ishak in Italian, and to Metavir in Swiss/German patients.
29 n array of seismogenic faults in the central Italian Apennines, where crustal extension and devastati
30 e influence of training systems on a typical Italian apple cultivar.
31 ompared them to the profiles of urban living Italians, as representative of people in the post-indust
32 topic signature was an excellent marker when Italian asparagus was compared with literature data for
33 he recent published field practice SOraFenib Italian Assessment (SOFIA) study.
34                  Italian Ministry of Health, Italian Association of Cancer Research, and Biodesix.
35 National Collegiate Athletic Association and Italian athletes (ages 18 to 25 and mean age 24 years, r
36 ducts (3129 determinations) sampled from the Italian authorities were successfully analyzed over a fo
37                    In Europe, refugia in the Italian, Balkan and Iberian peninsulas are believed to b
38                                      For the Italian base-case analysis, the cost-effective ICER obta
39  a multicenter cross-sectional study of 1309 Italian beta-thalassemia patients (mean age 36.4+/-9.3 y
40  and matched for disease duration (45 German-Italian bilingual speakers and 40 monolingual speakers)
41                 Here, we report a 7-year-old Italian boy with childhood-onset rapidly progressive enc
42 ubpopulation, we also included data from 172 Italian boys with DMD.
43                                              Italian buffalo mozzarella (BM) cheese metabolite profil
44 help to protect the designation of origin of Italian buffalo mozzarella.
45 scription of this case was published only in Italian by one of his students, Domenico Miliotti, there
46                      Data were compared with Italian cancer statistics.
47                 An independent cohort of 423 Italian cases and 467 Italian control individuals were u
48 LA4 and HLA-DQA1 in an independent cohort of Italian cases and control individuals.
49 d myocardial infarction (MI) in American and Italian Caucasian populations.
50 t al.[4] characterized the gut microbiota in Italian centenarians and semi-supercentenarians.
51 y followed up for a median of 10 years at an Italian center.
52 dred and ninety three adult patients from 27 Italian centers (recruited in 2011-2014) were analyzed.
53 PMF age </= 70 years recruited from multiple Italian centers and the Mayo Clinic (Rochester, MN), for
54 andidates for cardiac surgery enrolled in 11 Italian centers between March 2012 and March 2014.
55 multicenter, observational study including 7 Italian centers including patients with a history of ASA
56 42 patients (23%) had been rejected by other Italian centers, because of recipient selection (70 pati
57 HD) (n = 49), retrospectively recruited in 6 Italian centers, were submitted to ECP for second-line t
58 2, and December 31, 2007, at 8 hepatobiliary Italian centers.
59 isease (611) were enrolled in secondary care Italian centers.
60 ervention with BVS implantation for ISR at 7 Italian Centers.
61 free diet (controls) were collected among 11 Italian centres.
62 re analysed during ripening of a traditional Italian cheese, identifying parameters that could be mod
63                             We examined 1271 Italian children (age 4-18 years) with seasonal allergic
64 ffective in reducing preoperative anxiety in Italian children admitted to an Italian National Health
65 rsons (ages >/=65 years) that occurred in 12 Italian cities during the period 2006-2010.
66 n-based cohort study included 14,586 healthy Italian citizens enrolled within the Moli-sani study.
67 en from three different sites on the western Italian coast along a temperature gradient.
68 ve oils (EVOOs) from seven regions along the Italian coasts, by means of isotope ratio mass spectrome
69           The results were replicated in the Italian cohort (P=0.004, OR=0.71).
70 rm follow-up data (3 years) on the 5-patient Italian cohort involved in the LCA2 gene therapy clinica
71  relationship to clinical allergy in a large Italian cohort.
72 s with family history and 308 controls in an Italian cohort.
73                                         Four Italian commercial EVOO brands, all in both whole and st
74 HCV co-infected patients participating in an Italian compassionate-use program of ombitasvir/paritapr
75 multiplex array in 268 participants from the Italian component of the European Prospective Investigat
76 the United States that were collected by the Italian Consortium for the Genetics of ALS and the Inter
77 nthetic aperture radar measurements from the Italian constellation COSMO-SkyMed and the European sens
78 ore assessed the effectiveness of LCP in the Italian context (LCP-I) in improving the quality of end-
79 ependent cohort of 423 Italian cases and 467 Italian control individuals were used for replication.
80  patients with UM (2.4%; 95% CI, 0.9-5.7), 2 Italian control patients (1.7%; 95% CI, 0.1-6.5), 2846 p
81 , 1.8-2.7) but were not higher compared with Italian control patients (10 of 116 [8.6%]; 95% CI, 4.6-
82                                   Of the 116 Italian control patients, 67 (57.8%) were female, and th
83 nd in public databases or in 2,038 genotyped Italian controls.
84  is an important and traditional food in the Italian cuisine, and the eggs in pasta improve its nutri
85 ement of phenolic compounds in all the three Italian cultivar EVOOs analyzed, whereas the volatile co
86 unds in virgin olive oils produced from four Italian cultivars was assessed for two atmospheric condi
87 alysing the effect of genotype in the UK and Italian cumulative cohorts, individuals with deletions a
88  research was dedicated to the study, in the Italian daily diet, of the background activity concentra
89 st of Traditional Agro-food Products' of the Italian Department for Agriculture and itemised as 'slow
90                                In a Northern Italian discovery cohort (n = 477), neither DEPDC5 rs101
91  been considered one of the most appreciated Italian districts for wine production.
92 ports in English, German, French, Spanish or Italian documenting detailed ophthalmologic examination
93 molina and wholemeal flour of old and modern Italian durum wheats.
94                               The pathogenic Italian E22K mutation induces helix formation in the reg
95 cale drivers for the isotopic composition of Italian EVOOs.
96                                          The Italian experience suggests that pre-participation scree
97  delta(13)C and delta(18)O of 387 samples of Italian extra-virgin olive oil (EVOO) collected from 200
98                            Here, we report 2 Italian families affected by dominant chronic progressiv
99 ified in all cases sequenced in two separate Italian families, one variant per family, yielding a fre
100 197G-A>G) SNPs are linked to insomnia in our Italian families.
101 d the same mutation in two further unrelated Italian families.
102 ing a novel in-frame insertion/deletion in 2 Italian families.
103 Mb region on chromosome 6p in a SCA-affected Italian family by whole-genome linkage analysis.
104                 In this study, we present an Italian family with atypical HCM in which a novel diseas
105 corporating a high or low fish content in 20 Italian farms, focusing on two northern Italian regions
106         The aroma profiles of 10 traditional Italian fermented sausages were evaluated.
107 roperties of mucilages, extracted from seven Italian flax cultivars, were evaluated.
108 e an important contribution to the update of Italian Food Composition Databases.
109         This clone is closely related to the Italian gastroenteritis-associated HPB2262 and the invas
110                  During a 2-month period, 52 Italian gastroenterologists recorded clinical data of FC
111  this pragmatic cluster randomised trial, 16 Italian general medicine hospital wards were randomly as
112 lysis of 120 RNA samples corresponding to 10 Italian grapevine varieties collected at four growth sta
113 ficant differences between the Taiwanese and Italian groups.
114 , PP, B6, B12) and vitamin E level in the 80 Italian hams sampled are reported.
115 he micronutrient profile of some traditional Italian hams, representative of the major ham categories
116                                          The Italian hazelnut (Corylus avellana L.) cultivar "Tonda G
117        The study was performed in 5 northern Italian health districts during the 2006-2007, 2007-2008
118 rge population-based study from a network of Italian healthcare utilization databases aimed to assess
119 e=73, standard deviation (SD)=11) male (58%) Italian heart failure patients using structural equation
120 registered and prospectively monitored at 30 Italian hematological centers.
121 plied to the PITER cohort (representative of Italian hepatitis C virus-infected patients in care).
122                The volatile fractions of six Italian high-quality rice cultivars were investigated by
123 including 4 novel mutations from families of Italian, Hispanic, and Arabic ethnic origin.
124 emical parameters of a plumbing system in an Italian hospital.
125 oncology clinics at academic and nonacademic Italian hospitals between January 2011 and October 2013.
126 hort study was conducted at 17 Spanish and 1 Italian hospitals.
127 ent predictor of all-cause mortality in both Italian (HR 2.36) and Danish population (HR 3.04).
128       We characterized the genetic makeup of Italian hybridogenetic hybrids (P. kl.
129 ary fibre (ADF) was fortified in yogurt (Y), Italian (I) and Thousand Island (T) salad dressings.
130 sults were obtained for whey as well as both Italian ice creams and cheeses.
131 riculitis or meningitis remains a problem in Italian ICUs, and a strategy for reducing the prevalence
132 valence of ventriculitis or meningitis in 13 Italian ICUs.
133                We considered 946 consecutive Italian individuals at risk of nonalcoholic steatohepati
134                       English-, German-, and Italian-language studies from multiple electronic databa
135 s the maximum contamination level allowed by Italian legislation.
136                                    Using the Italian Liver Cancer (ITA.LI.CA) database as a training
137 0 untreated patients with HCC managed by the Italian Liver Cancer Group.
138 reatment cost of euro15,000/patient, and the Italian liver disease costs were used to evaluate qualit
139 om smokers within the randomized Multicenter Italian Lung Detection (MILD) trial.
140        One hundred and twenty years ago, the Italian malariologists Marchiafava and Bignami proposed
141   Here we describe the case of a 59 year-old Italian man suffering from Hepatitis B envelope Antigen
142 vored with white and black truffles from the Italian market were subjected to a blind analysis.
143 onging to six commercial brands, retailed in Italian markets, were tested for migration of BPA epoxy-
144 the breaded hake and plaice species, sold in Italian markets.
145 ncil, Project Grant, Cancer Australia Grant, Italian Medicines Agency, and Canadian Cancer Society Re
146      Canterbury Medical Research Foundation, Italian Medicines Agency.
147 ppraised by either the MD Score (MDS) or the Italian Mediterranean Index (IMI).
148                                          The Italian Mediterranean Index was used to evaluate the nut
149  which are instead highly represented in the Italian metabolome.
150                                          The Italian Ministry of Agricultural, Food and Forestry Poli
151                  Italian Ministry of Health; Italian Ministry of Foreign Affairs; EMERGENCY's private
152  7-T MR imaging protocol was approved by the Italian Ministry of Health and by the local competent et
153                                              Italian Ministry of Health and Maruzza Lefebvre D'Ovidio
154                                              Italian Ministry of Health, European Commission, Compagn
155                                              Italian Ministry of Health, European Commission, Compagn
156 gnia di San Paolo, Fondazione Cariplo Italy, Italian Ministry of Health, European Commission, Registr
157                                              Italian Ministry of Health, European Commission.
158                                              Italian Ministry of Health, Italian Association of Cance
159 ion for Health Research and Development, the Italian Ministry of Health.
160 for Research and Technology of Greece; AIRC; Italian Ministry of Health; AIRC Regional Project with F
161                                              Italian Ministry of Health; Italian Ministry of Foreign
162 n Anesthesiologists' Society, Pfizer Canada, Italian Ministry of Heath, Fonds NutsOhra, and UK Clinic
163 ling of volatile compounds of eleven typical Italian monocultivar EVOOs.
164                                          The Italian Moral Distress Scale-Revised evinces good reliab
165                                          The Italian Moral Distress Scale-Revised is a valid and reli
166                                          The Italian Moral Distress Scale-Revised is composed of 14 i
167 October 22, 2010, and October 22, 2012, at 8 Italian MS centers (secondary care outpatient clinics) a
168         This study analyzed data from ITAMY (ITalian multicenter study on Acute MYocarditis) and eval
169 beta(42), Abeta(40), and Abeta(42)-E22K (the Italian mutant) monomers in solution.
170                                           In Italian NAFLD patients, the rs641738 T allele was associ
171 ree dated 31 January 2008, which reports the Italian name for fish species of commercial interest, es
172  was carried out from the perspective of the Italian National Health Service.
173 e anxiety in Italian children admitted to an Italian National Health System pediatric hospital and ma
174 index patients with U-HAE recruited from the Italian Network for C1-INH-HAE (ITACA), we selected a la
175 perating conditions of a DC designed for the Italian Oil and Gas Company (Eni) (5200 m(2) of Informat
176 inating between "100% Italian" and "non-100% Italian" oils.
177 discrimination of the geographical origin of Italian olive oil (Ligurian and non-Ligurian) on the bas
178                                              Italian olive oils were richer in squalene and unsaturat
179  eras of cultural and scientific activity in Italian ophthalmology.
180 language other than English, French, German, Italian, or Greek, were excluded.
181 1, B, B1 and B4), was monitored in different Italian organic cereals and cereal products by using a l
182 y extra virgin olive oils of Italian and non-Italian origin (from Spain, Tunisia and blends of EU ori
183 a virgin olive oils bearing a designation of Italian origin on the labelling was tested by SIMCA.
184 cruited between May 2009 and June 2011 in 16 Italian outpatient clinics.
185                     Finally, a XVIII century italian painting whose the realization technique is unkn
186 enome-wide transcriptional profiles from 268 Italian participants of the European Prospective Investi
187               Median follow-up was 58 mo for Italian patients (interquartile range, 26-106 mo) and 39
188    The E167K variant was detected in 69 (9%) Italian patients and was associated with more severe ste
189 xtensive phenotypic characterization of five Italian patients from four unrelated families carrying d
190             We analyzed a cohort of 11 adult Italian patients in whom viral encephalitis developed.
191  and data analysis in a selected group of 26 Italian patients with (n = 17) and without (n = 9) inhib
192 e prospectively followed up, for 1 year, 796 Italian patients with different types of VWD to determin
193         Clinical and radiological data of 42 Italian patients with PML were analyzed.
194              We conducted genetic studies in Italian patients with U-HAE to identify novel causative
195 tients and then in a validation cohort of 71 Italian patients.
196  discrimination and calibration abilities in Italian patients.
197 fe in ParkinSon disease); SP0990) in treated Italian PD outpatients.
198 e and confirm the geographical origin of 177 Italian PDO (Protected Denomination of Origin) olive oil
199 ndance of C(4) plants allowed to distinguish Italian PDO from Spanish hams.
200 anned surgical intervention at a third-level Italian pediatric hospital from December 2013 to Septemb
201 c.1554_1555del leading to p.E518Dfs*2) in an Italian pedigree affected by sensorineural mild-to-moder
202 abria (haplogroups H1, H3, V, and U5b1), the Italian Peninsula (U5b3), and the East European Plain (U
203 isplatin-5-fluorouracil from the British and Italian perspectives.
204                           For comparison, 62 Italian players with similar ages, sport achievements, a
205 and Prunus (Cherry Plum, Plum 620, Ersinger, Italian Plum) were studied; bioaccessibility following i
206 er age groups, and with the results from the Italian population [4], to identify gut-microbial signat
207 ubsequently to evaluate the risk exposure of Italian population and infant population over the consum
208 biomarkers, and clinical outcomes in a large Italian population of patients with chronic heart failur
209 e rates are age and sex standardized for the Italian population of the 2011 census.
210 contribution for Dietary Reference Values in Italian population, and the antioxidant properties of so
211 d low-frequency variants in both a UK and an Italian population.
212 sponsible for cystic fibrosis (CF) among the Italian population.
213 GeneQuest II family-based population and the Italian population.
214 associated with a higher level of IgE in the Italian population.
215 ending from Sicily to Cyprus, where Southern Italian populations appear genetically closer to Greek-s
216 ucted a genome-wide association study in two Italian populations using additive, recessive and domina
217 ation was fairly divergent compared to other Italian populations.
218 red (FT-IR) spectroscopy study on the entire Italian postage stamps production is presented in this w
219 erize the statistical law according to which Italian primary school-size distributes.
220 e impact of Gluten-Friendly (GF) technology (Italian priority patent n degrees 102015000084813 filed
221                                 Pasta is the Italian product par excellence and it is now popular wor
222                  Ricotta cheese is a typical Italian product, made with whey from various species, in
223 rove the geographical origin of high-quality Italian products "White Asparagus from Bassano del Grapp
224 nic Liver Cancer (BCLC), Cancer of the Liver Italian Program (CLIP), and Japan Integrated Staging (JI
225 mmittee on Cancer stage, Cancer of the Liver Italian Program score, and Child-Pugh classification, tu
226 ona Clinic Liver Cancer, Cancer of the Liver Italian Program, and tumor-node-metastasis staging syste
227 8+/-7.1 years; women, 49.0%), as part of the Italian Project on Stroke in Young Adults (IPSYS).
228  ischemic stroke enrolled in the multicenter Italian Project on Stroke in Young Adults was conducted
229 ain ischemia, as part of the IPSYS registry (Italian Project on Stroke in Young Adults), who underwen
230            Fiore Sardo (FS) is a traditional Italian raw ewe's milk cheese carrying a Protected Desig
231                            Compared with the Italian reference population, patients had a significant
232 h hypertrophic cardiomyopathy evaluated at 2 Italian referral centers >3 decades.
233  among 21 consecutive patients enrolled at 3 Italian referral centers between June and November 2014
234 berries and currants) produced in a northern Italian region and at two sites in Romania and Poland co
235 n 20 Italian farms, focusing on two northern Italian regions (Friuli Venezia Giulia and Trentino).
236 emiologic prospective register that covers 2 Italian regions (population of 4476931 inhabitants accor
237 nd site was studied on four cultivars in two Italian regions during three consecutive years.
238          27 Saffron spices produced in three Italian regions, Abruzzo (L'Aquila), Umbria and Sardinia
239                      Sweet cherries from two Italian regions, Apulia and Emilia Romagna, were analyse
240 d white varieties and collected in different Italian regions, in order to address the traceability is
241 lets), 91% accuracy was obtained for the two Italian regions.
242 erising the aroma quality indices of the six Italian rice cultivars investigated.
243 rial membrane-based replication of Carnation Italian ringspot tombusvirus (CIRV) in yeast.
244 rial membrane-based replication of Carnation Italian ringspot tombusvirus (CIRV).
245 transistor functionalized with the Carnation Italian ringspot virus p19 protein biosensor.
246 Interestingly, the closely related Carnation Italian ringspot virus, which replicates on the boundary
247                           We quantified P in Italian ryegrass (Lolium multiflorum) and in field soil
248                   One hundred and forty-four Italian saffron samples produced in the years from 2009
249                                              Italian saffron turned out to be richer in total crocins
250 ging Fusarium mycotoxins were predominant in Italian samples compared to the Syrian.
251 ch, a sharper separation between Iranian and Italian samples was achieved.
252 ed with ochratoxin A and aflatoxins, whereas Italian samples with deoxynivalenol and 15-acetyldeoxyni
253                    TIMS was able, within the Italian samples, to discriminate different geographical
254  chemical variations between Argentinian and Italian samples.
255 ow citropten and high bergamottin content in Italian samples.
256  A previous randomized clinical trial by the Italian Sarcoma Group (ISG) had shown a survival benefit
257 nhibitor-positive and 174 inhibitor-negative Italian severe hemophilia A patients using a TaqMan geno
258                                          The Italian severe/uncontrolled asthma (SUA) web-based regis
259 nk") signs from (the historically unrelated) Italian Sign Language, Sign Language of the Netherlands,
260 he identification of APOPT1 mutations in two Italian sisters and in a third Turkish individual presen
261 l, phase 3 superiority trial conducted at 16 Italian sites.
262 outh Napa earthquake using SAR data from the Italian Space Agency's COSMO-SkyMed and the European Spa
263  CBE patients of Australian, British, German Italian, Spanish and Swedish origin and 1,354 ethnically
264 ntative of the two main production areas for Italian sparkling wines, by HS-SPME-GCxGC-TOF-MS and mul
265 unities of Southern Italy cluster with their Italian-speaking neighbours suggesting a long-term histo
266 eld GPS data, regional measurements from the Italian Strong Motion and National Seismic networks, and
267  evaluated) after a median of 8 weeks in the Italian study and 100% (24 of 24) after a median of 12 w
268 administered for a median of 16 weeks in the Italian study and 18 weeks in the U.S. study.
269  selected 121 live-born singletons after KT (Italian study group of kidney in pregnancy, national cov
270                      Importantly, a parallel Italian study validated this new hematologic remission p
271     A cost-projection model was based on the Italian study, replicating its data in terms of athlete
272             We analyzed data reported to the Italian Surveillance System for Acute Viral Hepatitis fr
273 istical techniques for the classification of Italian sweet cherries based on their different geograph
274            Genetic analysis highlighted that Italian swine IDVs are closely related to the D/swine/Ok
275 , we detect the signature of nepotism in the Italian system, with a declining trend.
276                             We recruited 200 Italian T2D families phenotyping them for primary insomn
277 at spices produced at different sites of the Italian territory can be discriminated with good accurac
278 e cohort of patients with ALS observed by an Italian tertiary multidisciplinary center.
279                                              Italian tertiary referral center medical-surgical ICU.
280  included psoriatic patients who attended an Italian tertiary referral hospital from 2009 to 2012.
281 ficantly lower (log-rank test, p < 0.001) in Italian than in Taiwanese patients, the ITA.LI.CA score
282  fibrosis in a cross-sectional cohort of 815 Italian therapy-naive CHC patients.
283 elta per thousand values between Chinese and Italian tomato samples, irrespective of the treatment ty
284                   We consider the German and Italian transmission grids.
285 nrollment was completed (28 patients) in the Italian trial in April 2013 and is still open (26 of 36
286 ints were the complete response rate (in the Italian trial) and the overall response rate (in the U.S
287                                       In the Italian trial, after a median follow-up of 23 months, th
288  1418 low-risk controls recruited in 2 large Italian Units in the same period (2000-2014).
289  of microbial richness and biodiversity than Italian urban controls.
290 alyses, for the authentication of the unique Italian Valle d'Aosta Arnad Protected Designation of Ori
291 e oil phenolic extracts (OOPEs) from several Italian varieties were studied.
292  renowned soloists each blind-tested six Old Italian violins (including five by Stradivari) and six n
293                                          Old Italian violins are routinely credited with playing qual
294 s for the purported tonal superiority of Old Italian violins by investigating varnish and wood proper
295 hallenge to near-canonical beliefs about Old Italian violins.
296             The analysis of 40 Syrian and 46 Italian wheat grain samples interestingly showed that Sy
297 al variations of Cd, Pb and Cu content in an Italian white wine were studied over the period 1995-201
298 rifying the authenticity of 178 samples of 3 Italian wine brands: Barolo, Barbera, and Grignolino des
299 mpounds declined by 50-57% in the French and Italian wines over a 12-months period.
300 les, by 86-91% in French wines and 23-35% in Italian wines, while fruity aroma compounds declined by

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