ライフサイエンスコーパス: Johne

1 Johne's disease (JD) is a chronic enteric disease in cat

2 Johne's disease (JD), a persistent and slow progressing

3 Johne's disease (paratuberculosis) of cattle is widespre

4 Johne's disease is a chronic diarrhea affecting all rumi

5 Johne's disease is a chronic enteritis of ruminants asso

6 Johne's disease is caused by Mycobacterium avium subsp.

7 Johne's disease, caused by Mycobacterium paratuberculosi

8 d by sera from 100% of animals with advanced Johne's disease (clinical stage) (12 cattle, 2 goats, an

9 nto the milk and feces of cows with advanced Johne's disease, allowing the transmission of M. avium s

10 urther testing as vaccine candidates against Johne's disease.

11 ets for vaccine and drug development against Johne's and Crohn's diseases.

12 (PBMCs) from control uninfected (n = 4) and Johne's disease-positive (n = 6) Holstein cows.

13 s from Johne's disease-positive (n = 6), and Johne's disease-negative (n = 5) Holstein cattle.

14 jor agents in bovine respiratory disease and Johne's disease.

15 human tuberculosis, bovine tuberculosis and Johne's disease.

16 Similarities between Johne's disease in ruminants and Crohn's disease in huma

17 w generations of diagnostic tests for bovine Johne's disease.

18 cterium avium subsp. paratuberculosis causes Johne's disease in cattle and is a serious problem for t

19 cterium avium subsp. paratuberculosis causes Johne's disease in ruminants, a chronic enteric disease

20 cterium avium subsp. paratuberculosis causes Johne's disease, an enteric infection in cattle and othe

21 symptoms similar to those found in clinical Johne's disease.

22 ual progression from subclinical to clinical Johne's disease in cattle.

23 ulosis results in a granulomatous enteritis (Johne's disease) that is often fatal.

24 tectable early in the course of experimental Johne's disease, even preceding the development of speci

25 e a major impact on improved diagnostics for Johne's disease.

26 commercially available diagnostic tests for Johne's disease.

27 levels (>1.5-fold; P < 0.05) in tissues from Johne's disease-infected animals relative to noninfected

28 ne expression profiles of ileal tissues from Johne's disease-positive (n = 6), and Johne's disease-ne

29 ansforming growth factor beta (TGF-beta), in Johne's disease has not been investigated as yet.

30 ratuberculosis (MAP), the causative agent of Johne disease in cattle and other ruminants, is proposed

31 . paratuberculosis is the causative agent of Johne's disease in animals and has been hypothesized to

32 is (Map) strain K-10, the causative agent of Johne's disease in cattle and other ruminants.

33 The causative agent of Johne's disease is Mycobacterium avium subsp. paratuberc

34 . paratuberculosis is the causative agent of Johne's Disease, an economically important intestinal ai

35 M. paratuberculosis), the causative agent of Johne's disease, are approved for use in livestock.

36 avium subsp. paratuberculosis, the agent of Johne's disease, infects ruminant hosts by translocation

37 Development of models to mimic aspects of Johne's disease remains an elusive goal because of the c

38 mental evidence defining MAP as the cause of Johne's disease and the issues and controversies surroun

39 vium subsp. paratuberculosis is the cause of Johne's disease in cattle and other ruminants.

40 array to identify antigens in the context of Johne's disease.

41 f immunoassays specific for the diagnosis of Johne's disease in cattle requires antigens specific to

42 ific method for the serological diagnosis of Johne's disease is unavailable.

43 is strains to understand the epidemiology of Johne's disease.

44 could result in cells within the lesions of Johne's disease-positive cattle that are highly resistan

45 es are pivotal events in the pathogenesis of Johne's disease.

46 To further understand the pathology of Johne's disease, we compared the gene expression profile

47 ined from a cow exhibiting clinical signs of Johne's disease.

48 all, novel insights into the early stages of Johne's disease were obtained, and a practical model of

49 Clinical symptoms of Johne's disease include persistent diarrhea, inappetence

50 report suggest that many outward symptoms of Johne's disease may be due to IL-1alpha toxicity.

51 n increased protein expression in tissues of Johne's disease-positive cattle relative to tissues from

52 F1 (27.5-fold) gene expression in tissues of Johne's disease-positive cows relative to tissues from c

53 c wasting disease termed paratuberculosis or Johne's disease, whereas M. avium subsp. avium causes on

54 Paratuberculosis (Johne's disease) is a fatal disease of ruminants for whi

55 or the diagnosis of clinical and subclinical Johne's disease (paratuberculosis) compared to bacteriol

56 cells (PBMCs) from clinical and subclinical Johne's disease-positive Holstein cows (n = 2 per group)

57 tion is a sensitive indicator of subclinical Johne's disease.

58 ammatory bowel diseases (IBD) and veterinary Johne's disease suggests that Mycobacterium avium subsp.

59 Sera from animals with Johne disease, but not sera from uninfected cattle, reac

60 for use in the serodiagnosis of animals with Johne's disease at all stages of infection.

61 tered with strains derived from animals with Johne's disease.