ライフサイエンスコーパス: K

1 K (lysine) acetyltransferase 8 (KAT8), an important comp

2 K(+) channel regulatory mechanisms alter, and are altere

3 K(lysine) acetyltransferase 8 (KAT8, also known as MOF)

4 K-means clustering was then used to select images from d

5 K-Ras-beta-catenin tumors showed up-regulation of beta-c

6 ity-functional theory (DFT) computation at 0 K.

7 aximum values of 0.0529/K at 24 K and 0.0057/K at 457 K for the Y2O3:1%Er(3+), 0.5%Ho(3+) at 121 mW/m

8 ower, and reach two maximum values of 0.0529/K at 24 K and 0.0057/K at 457 K for the Y2O3:1%Er(3+), 0

9 cting spin-valve effect with a T c change 1 K in superconductor/half-metal structures, in which case

10 ited wild-type, but not C723S mutant, Kv11.1 K(+) currents.

11 rkably high power factor of 904 microW m(-1) K(-2) at 300 K for flexible thermoelectrics, approaching

12 ce thermal conductivity as low as 0.4 Wm(-1) K(-1) and a high thermoelectric figure of merit, which c

13 2 M.S/m, thermal conductivity of 264 W.m(-1).K(-1) and microhardness of 278 HV were achieved for the

14 m(-1).K(-1)), CsPbBr3 (0.42 +/- 0.04 W.m(-1).K(-1)), and CsSnI3 (0.38 +/- 0.04 W.m(-1).K(-1)).

15 es composed of CsPbI3 (0.45 +/- 0.05 W.m(-1).K(-1)), CsPbBr3 (0.42 +/- 0.04 W.m(-1).K(-1)), and CsSnI

16 1).K(-1)), and CsSnI3 (0.38 +/- 0.04 W.m(-1).K(-1)).

17 that were infected as larvae with 10,000 (10 K) or 40,000 (40 K) live N. ceranae spores/bee, Vg titer

18 mperature independent below approximately 10 K, and a large kinetic isotope effect (KIE) is observed

19 sults in D2-over-H2 selectivity of 11 at 100 K, to the best of our knowledge the largest value known

20 nding using X-ray structures obtained at 100 K.

21 ositions and linewidths for samples near 100 K are perturbed relative to those near 273 K.

22 bility and the latter is caused by the 1000 K Mott metal-insulator transition, for which the thermal

23 pectively, and at temperatures reaching 1073 K.

24 n and electrostatic interactions for T > 110 K and larger contributions from clamping losses for T <

25 ntributions from clamping losses for T < 110 K.

26 inant dissipation pathways occurs at T 110 K with relatively larger contributions from phonon-phono

27 y was established from a low-temperature 120 K sc-XRD study at 0.90 A resolution.

28 transition into the low-density form at 130 K, but remains diffusive.

29 g temperature in BaFe2As2 crystal (T N = 132 K to 136 K) by improving in-plane electronic defects and

30 ture in BaFe2As2 crystal (T N = 132 K to 136 K) by improving in-plane electronic defects and reducing

31 reversal (770.8 K) and magnetic blocking (14 K).

32 (T) between their freezing point and 298.15 K (25 degrees C).

33 utions over temperature range (288.15-318.15)K at pressure, p=0.1MPa.

34 at emerges in the FeAs layer below T 0 155 K of Sr2VO3FeAs, a naturally assembled heterostructure o

35 Process II is observed above 170 K, with activation energy typical of beta relaxations in

36 At low temperature (T </= 170 K), when QMT is the dominant pathway, the tunneling cont

37 Below 18 K, this small additional magnetic incommensurability dis

38 Direct visualization at 1873 K of 0% to 8% molten FeAl droplets suspended in a SiO2 e

39 ients as indicated by higher K N -values, 2) K N is a good predictor of instantaneous net ecosystem C

40 te and regions unique to the mammalian IP5 2-K, as an unexpected basic patch on the protein surface.

41 F) (1-isq), and the amidophenolate (L(2-) ) [K(THF)2 ][((dipp) ap)2 Nd(THF)2 ] (1-ap) and [K(18-crown

42 on of tri(3,5-tert-butylphenyl)methane at 20 K reveals an intermolecular C-H...H-C distance of only 1

43 rriers as well as polariton lasing up to 200 K under non-resonant optical pumping.

44 order at an intermediate temperature of 223 K and a larger strain rate of 2.5 x 10(-2) s(-1); the di

45 850 (37%) of 2301 K pneumoniae samples and 77 (19%) of 402 E coli samples

46 directly measured at temperatures below 233 K (-40 degrees C), conditions necessary to form cirrus c

47 tricritical point at T tri approximately 24 K and H tri approximately 52 T.

48 d reach two maximum values of 0.0529/K at 24 K and 0.0057/K at 457 K for the Y2O3:1%Er(3+), 0.5%Ho(3+

49 large temperature fluctuations (DeltaT 24 K).

50 obalt-doped BaFe2As2 crystal (T c = 23 to 25 K) by precipitating-out the cobalt dopants and giving la

51 lutions and in porphyrin compounds at 20-260 K.

52 0 K are perturbed relative to those near 273 K.

53 g current as high as 200 A was applied at 28 K (below the critical current) without any operating or

54 of MSA and methylamine (MA) at 1 atm and 294 K in the presence and absence of water vapor using an ae

55 In dry, degassed acetone at 295 K, the radical 2 has a half-life, tau1/2 = 49 h (DeltaH(

56 in this system are of order 0.1 s(-1) at 296 K, while the 1,4 H-shift is calculated to be orders of m

57 er UV light irradiation, both at 273 and 298 K, JUC-62 showed 51% and 34% lower CO2 uptake, respectiv

58 free energy barriers for 1,4-H shifts at 298 K are consistently predicted to be ca. 25 kcal/mol, wher

59 rotation barrier of 6.5 kcal mol(-1) at 298 K in spite of the bulkier aryl groups.

60 , form inclusion complexes with baskets 1-3 (K = 6-2243 M(-1)).

61 technique in the temperature range of 25-300 K.

62 ower factor of 904 microW m(-1) K(-2) at 300 K for flexible thermoelectrics, approaching the values a

63 ude higher resistance-switching ratio at 300 K, which is attributed to the intricate interplay betwee

64 in the gas phase and at a temperature of 300 K, the dominant interaction between SO2 and H2O is (SO2)

65 nts of temperature dependence from 40 to 320 K demonstrate a shift of the peak in the kappa to lower

66 bI3 with a narrow transition ( 5 K) near 327 K.

67 ecular cations in FAPbI3 between 4 K and 340 K and the nature of their interaction with the surroundi

68 the gas phase at temperatures around 320-350 K observed in the isomerization reaction of a hydroxycar

69 Here, we report high-precision (41)K/(39)K measurements for samples from the Bay of Islands ophio

70 nd we document large variations in (41)K/(39)K, covarying with previous determinations of (87)Sr/(86)

71 of the molecular cations in FAPbI3 between 4 K and 340 K and the nature of their interaction with the

72 t that the Cryptosporidium lipid kinase PI(4)K (phosphatidylinositol-4-OH kinase) is a target for pyr

73 d as larvae with 10,000 (10 K) or 40,000 (40 K) live N. ceranae spores/bee, Vg titers were significan

74 e bias field (HEX) started to appear at T 40 K and its value increased by decreasing the temperature.

75 confirm that the former is caused by a 400 K non-linear-transport-driven instability and the latter

76 erties), which can harvest waste heat at 400 K with efficiencies about 7% to 8%.

77 The calculated Boltzmann distribution at 400 K yields an enthalpy of binding in reasonable agreement

78 ite, and we document large variations in (41)K/(39)K, covarying with previous determinations of (87)S

79 Here, we report high-precision (41)K/(39)K measurements for samples from the Bay of Islands

80 ocity and cooling rate of 10.3 mm/s and 4500 K/s, respectively.

81 lues of 0.0529/K at 24 K and 0.0057/K at 457 K for the Y2O3:1%Er(3+), 0.5%Ho(3+) at 121 mW/mm(2) exci

82 f magnitude, from less than a second at 12.5 K, 100 mW/cm(2) to (an estimated) several hours at 50 K

83 s of CH3NH3PbI3 with a narrow transition ( 5 K) near 327 K.

84 /cm(2) to (an estimated) several hours at 50 K, 1 mW/cm(2).

85 iency in the temperature range of 400 to 500 K.

86 9% at terminals' temperatures of 375 and 530 K.

87 ced metamagnetic phase transitions (T N = 58 K) and high spontaneous polarization ( 63.3 muC.cm(-2))

88 Below approximately 60 K the rebinding kinetics do not follow these predictions

89 olid-state at ambient temperatures, up to 60 K below their glass transition temperature (Tg), by subj

90 material exhibits a zT = 1 over the 513-613 K range.

91 structured with TFMG/TE are annealed at 673 K for 8-360 hours and analyzed by electron microscopy.

92 P array with 690,662 unique SNPs (herein 690 K array) that were relatively evenly distributed across

93 The V LSSE peak at 75 K is attributed to the H KS and M S (saturation magnetiz

94 ice has an 8 microm cut-off wavelength at 77 K and exhibits a quantum efficiency of 31% for a 2 micro

95 at 3.4, 5, and 7.7 mum, respectively, at 77 K.

96 tests performed at temperatures between 773 K and 923 K and stress range of 100 MPa-300 MPa indicate

97 large energy barrier to spin reversal (770.8 K) and magnetic blocking (14 K).

98 tivity occurred at approximately 848 and 898 K following the decomposition of antigorite to forsterit

99 [Formula: see text] ([Formula: see text] 91 K A) is a new elastobaric coefficient.

100 formed at temperatures between 773 K and 923 K and stress range of 100 MPa-300 MPa indicate both a si

101 POINTS: Large conductance, Ca(2+) -activated K(+) (BKCa ) channels play important roles in mammalian

102 endothelial cells lack the Ca(2+) -activated K(+) channels present in arterial endothelium to generat

103 rge-conductance voltage and Ca(2+)-activated K(+) (BK) channel have a key role in the ethanol effect

104 -conductance, calcium- and voltage-activated K(+)(BK) channel consists of the pore-forming alpha subu

105 bacteriovorus acting therapeutically against K. pneumoniae in serum, informing future research into t

106 ling and rapid-scan X-ray Kbeta emission and K-edge absorption spectroscopy as well as quantum chemis

107 ypes, including subtypes A1, F, G, H, J, and K and unclassified fragments, including one subtype CRF2

108 e quantification of elements (Mg, Ca, Na and K) through LIBS was done using calibration curve method

109 Na(+) and K(+) exhibit a significant preference for the centroid o

110 e sites to alternatively transport Na(+) and K(+) This ping-pong mechanism is supported by transient-

111 depending on the relationship between r and K.

112 (THF)2 ][((dipp) ap)2 Nd(THF)2 ] (1-ap) and [K(18-crown-6)][((dipp) ap)2 Nd(THF)2 ] (1-ap crown) spec

113 As K-edge XANES spectroscopy revealed some reduction of As(

114 mutant lung cancer cell lines classified as K-Ras-dependent or -independent for co-dependency on pro

115 FOS and CGA, some mineral elements, such as K, Ca and P, and essential amino acids, such as tryptoph

116 +) channel in health and disease, as well as K(+) channels as therapeutic targets, were contributed b

117 > 0.9) and the following parameters: AUGC90, K(trans), and maximum slope enhancement (intraclass corr

118 nterococcus faecium, S taphylococcus aureus, K lebsiella pneumoniae, A cinetobacter baumannii, P seud

119 as a potent inhibitor of human cathepsins B, K, and L ( Ki = 6.87, 0.49, and 0.34 nM, respectively).

120 targeting sequence peptide (F-PTS1, acetyl-C{K(FITC)}GGAKL) for investigating pH regulation of glycos

121 the phases were allowed to separate and Ca, K, Na, and Mg were determined in aqueous phase by means

122 s, easily ionized elements (EIEs), i.e., Ca, K, Mg, and Na, as well as the foreign ions (Al, Cu, Fe,

123 The levels of the minerals: Ca, K, Mg, Na, P, and the trace elements: Cd, Cu, Fe, Mn, Ni

124 letely different fold from that of canonical K(+) channels.

125 structure (XANES) spectroscopy at the carbon K-edge (280-350 eV) is a very powerful method to probe c

126 using on the functional roles of the cardiac K(+) channel in health and disease, as well as K(+) chan

127 K m = 0.56 microM(-1)s(-1)) than NPP (k cat /K m = 0.044 microM(-1)s(-1)).

128 ene was over ten fold higher for GPP (k cat /K m = 0.56 microM(-1)s(-1)) than NPP (k cat /K m = 0.044

129 Wild-type and cathepsin K knockout mice were rendered diabetic by streptozotocin

130 RNAs encoding for RANKL, TRAP, and Cathepsin K.

131 n lower expression and activity of cathepsin K compared with resting unpolarized macrophages.

132 sts, pharmacological inhibition of cathepsin K, or treatment with calcineurin inhibitor rescued cells

133 IFN-gamma exhibited low levels of Cathepsin K, TRAP, RANK, and tumor necrosis factor receptor-associ

134 tosis, which were mitigated in the cathepsin K knockout mice.

135 de (TAT-C1aB) suppressed enhanced whole-cell K(+) currents produced by a mutated form of Kv2.1 mimick

136 utility maximization problem to the classic K -means clustering problem, which can then be efficient

137 ando X-ray absorption spectroscopy at the Co K-edge.

138 ore effective than PEf1 in infecting E. coli K-12 in pure cultures, PEf1 was 20-fold more effective i

139 ppressing a model enteric bacterium (E. coli K-12) in mixtures with soil bacteria (Pseudomonas putida

140 NA damage (SOS) response in Escherichia coli K-12, despite the fact that pressure cannot compromise t

141 rded as a biomimetic alternative of columnar K(+)-water wires observed for the natural KcsA channel.

142 ABSTRACT: Small conductance K(+) (SK) channels have been implicated as modulators of

143 forms of Ca(2+) -activated small conductance K(+) (SK) channels in the murine SAN.

144 These data confirm K. pneumoniae colonization is a significant risk factor

145 In contrast, K = 3 indicated incipient host differentiation between l

146 These findings uncover a critical K(+)-Ca(2+)-adrenergic signaling axis that acts to dampe

147 xperiments show that direct, anhydrous Cs(+)-K(+) exchange is kinetically viable and leads to the for

148 Cu K-edge EXAFS confirms that the immobilized cluster 2 is

149 y that depends on the cycling of cytoplasmic K(+) levels.

150 ng constant value (1.09x10(3) at 310 degrees K).

151 nes STRUCTURE analysis with the Evanno Delta K analysis and visualization of results using STRUCTURE

152 at H2O2-elicited dilation involves different K(+) channels in non-CAD versus CAD, resulting in an alt

153 Second, we used different K(+) concentrations to shift the equilibrium between non

154 nct receptor subtypes coupled with different K(+) channels, astrocyte-derived ATP differentially modu

155 ction can lead to arrhythmias, and discusses K(+) channel-based therapeutics.

156 ells harboring a different oncogenic driver (K-562 cell line) did not result in selective growth inhi

157 parated up to 220 mum (300 mum with elevated K(+)).

158 evoked by injecting solutions with elevated [K(+)].

159 ellent adaptability to adverse environments, K(+) concentration remains at a relatively constant leve

160 st of a GPCR and G protein tethered by an ER/K linker flanked by FRET probes.

161 not PtdIns(3,4,5)P3 was sufficient to evoke K-Ras translocation.

162 ensory web that converts changes in external K(+) into rapid, 'inside-out' electrical signaling to di

163 potential at subphysiological extracellular K(+) concentrations or pathological hypokalaemia, howeve

164 on selectivity, sensitivity to extracellular K(+), and pharmacology, consistent with an impact on con

165 ivation of inward current when extracellular K(+) ([K(+) ]o ) was increased.

166 rization imposed by elevating extracellular [K(+)], and KCNQ2 was required for potentiation of SMIT a

167 Mild block occurred for K(+) currents representing IKr (CHO cells expressing hER

168 F/B), shell-to-fruit (S/F), kernel-to-fruit (K/F), mesocarp-to-fruit (M/F), oil per palm (O/P) and oi

169 microscopy in live cells, we show that G12V K-Ras exists as a mixture of monomers, dimers and larger

170 exhibit temperature sensitivity of -1.8 GHz K(-1) and can be configured as ultra-high sensitivity th

171 ding suggests that replacing an amine group (K side chain) with a primary amide group (Q side chain)

172 i) undergoes a hydrogen bond change in D --> K transition and (ii) deprotonates in K --> M transition

173 SSE), magnetocrystalline anisotropy field (H K) and surface perpendicular magnetic anisotropy field (

174 (SC) ion-selective electrodes (ISEs) (H(+), K(+), and Na(+)) have outstanding performance characteri

175 Hence, in the H(+),K(+)-ATPase, the ability of the M8 arginine to donate an

176 A undergoes mode-shift of gating when having K(+) as the permeant ion; (ii) that Cs(+) or Rb(+), know

177 regulation of the endogenous retrovirus HERV-K could both initiate and sustain activation of the immu

178 ronounced N gradients as indicated by higher K N -values, 2) K N is a good predictor of instantaneous

179 nnels in cardiac electrophysiology, i.e. how K(+) currents shape the cardiac action potential, and ho

180 different surfaces exhibit nearly identical K values after being exposed to kitchen grime with value

181 ity was significantly reduced by SzV-1287 in K/BxN-arthritis.

182 (htel-22) and d[TAG3(TTAG3)3TT] (htel-25) in K+ solutions.

183 D --> K transition and (ii) deprotonates in K --> M transition.

184 potassium channel, two essential elements in K(+) uptake in plant cells.

185 s (parallel and antiparallel G-quadruplex in K+ and Na+, respectively).

186 Independently, K-Ras4B allosterically activates p110.

187 e I hair cells causes unstable intercellular K(+) concentrations, altering the biophysical properties

188 Although exchange of interlayer K(+) for Cs(+) is nearly thermodynamically nonselective,

189 ial cell characteristics in an international K. pneumoniae isolate collection (n = 48), with a range

190 els suggests variant-dependent intracellular K(+) loss and cytotoxicity does not drive kidney disease

191 m may follow either an ionic route involving K(+) and (t)BuO(-) ions or a neutral heterolytic route i

192 Both the outward and inward K(+) currents shifted Veq K(+) consistent with K(+) accu

193 Coupling the co-localization results to iron K-edge X-ray absorption spectroscopy fitting results all

194 average Earth system climate sensitivity is K (1sigma) per CO2 doubling, which is notably higher tha

195 of inward current when extracellular K(+) ([K(+) ]o ) was increased.

196 intercalation by several alkali metals (Li, K, Rb and Cs) and alkali-earth Ca.

197 s Rhizophagus irregularis under high and low K(+) regimes for 6 weeks.

198 f yeast strain G19, and complemented the low-K(+) -sensitive phenotype of Arabidopsis akt1 mutant, in

199 cetyltransferase activity on histone H3 Lys (K) 122, demonstrating that RSV infection activates BRD4

200 myelination, while the intensity of the [M + K](+) adducts was stronger in those sections from mechan

201 site also exhibits improved thermal (>65 W/m-K) and electrical ( 700 S/cm) conductivities, as well as

202 In the clinical keratoconus eyes, the mean K, back difference elevation (BDE), pachymetric progress

203 Histone Lys-to-Met (K-to-M) mutations act as gain-of-function mutations to i

204 be 244 +/- 11 pS (n = 17; symmetrical 150 mm K(+) ) with open probability being both voltage- and Ca(

205 that is much less substantial than at 20 mM K(+) (-120 mV vs -210 mV).

206 ation at higher Mo loadings, indicated by Mo K-edge X-ray absorption spectra.

207 KCNE2 may regulate multiple K(+) channels in beta cells, including the T2DM-linked K

208 R., Murakami, K., Irie, Y., Hentzer, M., Nielsen, T.

209 as well as high thermoelectric power (22 muV/K) at room temperature.

210 n conjunction with experimentally measured N K-edge absorption spectra, reveals the different nature

211 nhibition alone, or combined NO, PGs, Na(+) /K(+) -ATPase (ouabain) and KIR channel inhibition (n = 6

212 the co-expressed water-translocating Na(+) /K(+) /2Cl(-) cotransporter promoted TRPV4 activation des

213 oteins in male organisms, inductions of Na(+)K(+)/ATPases, and strong inhibitions of molt-related pro

214 s pore-domain chimera is permeable to Na(+), K(+), and Ca(2+) ions, and remarkably, is also robustly

215 NaCl reabsorption, therefore reducing Na(+)/K(+) exchange.

216 ocedure enabled us to evaluate whether Na(+)/K(+)-ATPase uses the same sites to alternatively transpo

217 The time course of the Na-/K-ATPase inhibition in the cell culture was demonstrated

218 ns revealed no effect of retinoschisin on Na/K-ATPase-mediated ATP hydrolysis and ion transport.

219 In contrast, NH2-K(Boc)LVFF-CONH2 undergoes hydrophobic collapse at a low

220 Oncogenic KRas, HRas, and NRas (K-Ras, H-Ras, and N-Ras) differentially populate distinc

221 r for infection in ICU, and indicate 50% of K. pneumoniae infections result from patients' own micro

222 emotaxin 2, Regucalcin, and Cyclin-D1 and of K-Ras effectors, including phosphorylated extracellular

223 ) , resulting in decreased concentrations of K(+) and Na(+) , as compared to wild-type Z. xanthoxylum

224 No evidence of K-ras mutations was observed.

225 concomitant with altered gene expression of K(+)-channel subunits and ion channel modulators, releva

226 ion replacement, we show that inhibition of K(+) transport abolishes RBC electrophysiological rhythm

227 uadratic diversity metric is a good proxy of K N .

228 ctrophysiology through dynamic regulation of K(+) transport.

229 ing paper focuses on the integrative role of K(+) channels in cardiac electrophysiology, i.e. how K(+

230 bited a significant decline in net uptake of K(+) and Na(+) , resulting in decreased concentrations o

231 trate that continued expression of oncogenic K-RAS is required for the survival of primary and metast

232 metastatic colon cancers and that oncogenic K-RAS activates TGF-beta signaling to promote tumor inva

233 s is dependent on transmembrane Na(+) and/or K(+) flux and the activation of heat shock protein 90 (H

234 signment of each Raman feature near the M or K points of the Brillouin zone.

235 rious tumor cells expressing B-Raf(V600E) or K-Ras(G12C/D) Intriguingly, coimmunoprecipitation and in

236 ere are several Ca(2+) -sensitive potassium (K(+) ) currents such as the slowly activating delayed re

237 true for samples containing both proteinase K (PK)-sensitive and PK-resistant PrP(Sc) and samples co

238 Both Husk and Ash provided K, which also played a role in yield improvement.

239 dies defined the sequence of the NDSM as Psi-K-x-E/D-x1-x2-(x3/E/D)-(x4/E/D)-xn and determined that K

240 We developed a new method to quantify [K(+)] from T-wave analysis and tested its clinical appli

241 CI leads to the development of several rare K-ras-independent forms of PC, with infrequent PDAC.

242 The rapidly activating delayed rectifier K(+) channel (IKr) is encoded by the human ether-a-go-go

243 Inward rectifier K(+) channel subfamily 2 (Kir2) channels primarily maint

244 hat ZxAKT1 functions as an inward-rectifying K(+) channel.

245 KEY POINTS: Endothelial inwardly rectifying K(+) (Kir2.1) channels regulate flow-induced vasodilatat

246 f a low-voltage-activated outward rectifying K(+) current, IK,L , whose biophysical properties and mo

247 +) uptake to sarcoplasmic reticulum, reduced K(+) currents, and increased propensity to arrhythmias.

248 Agreement between KECG and reference [K(+)] from blood samples was promising (error: -0.09 +/-

249 atients with blaOXA-232 carbapenem-resistant K. pneumoniae infections were identified at a tertiary c

250 It affords either the [Co(I)((R)salophen)K] complexes or the [Co(II)2(bis-salophen)M2] (M = Li, N

251 t with suppression of a muscarinic-sensitive K(+)-current, or M-current.

252 Since K(+), NO3(-), and NH4(+) are major ions taken up by plan

253 c decreases in beta-catenin targets and some K-Ras effectors, leading to reduced tumor cell prolifera

254 KCC2 is a neuron-specific K(+)-Cl(-) cotransporter essential for establishing the

255 Finally, our data suggests K-to-M mutations may provide a useful strategy for alter

256 , M., Roller, L., Jobichen, C., Swaminathan, K., Mizuguchi, J., Iwanaga, S., Nuttall, P.

257 equence homology to the canonical tetrameric K(+) channels and lacks the TVGYG selectivity filter mot

258 We find that K. marmoratus genome maintains number and composition of

259 This study is the first to show that K(+) channel modulatory subunits KChIP1, KChIP2, and DPP

260 Our current studies show that K-Ras-dependent cells are refractive to PKCdelta-driven

261 rystallographic and biochemical studies that K-80003 binds to and stabilizes tRXRalpha tetramers via

262 se from ATP into the medium, suggesting that K. mikimotoi cells were expressing extracellular hydrola

263 The K m and k cat of AnCDA for the first deacetylation of pe

264 The K(+) channel pore-forming subunit Kv4.3 is expressed in

265 of cocaine, flutamide, flufenamic acid, the K salt of penicillin G, and form 4 of the drug 4-[4-(2-a

266 ession of ComK, the master regulator for the K-state, and reduces transformability.

267 rt on a high-quality genome assembly for the K. marmoratus South Korea (SK) strain highlighting the d

268 functional role of endogenous IL-1R2 in the K/BxN serum transfer arthritis model and in IL-1beta- or

269 ependent tissue inflammation as shown in the K/BxN serum transfer arthritis model.

270 ening lifts the phonon Kohn anomaly near the K point for graphene encapsulated in hBN, and shifts the

271 The magnitude of the K(d)M282-90 CD8(+) T cell response in TLR agonist-treate

272 work depends on the protonation state of the K-channel residue K362.

273 Here we report that one of the K-Ras splice variants, K-Ras4a, is subject to lysine fat

274 tance plasmids, particularly variants of the K. pneumoniae carbapenemase.

275 early, moderate, and severe KOA based on the K/L score.

276 Expression of ZxAKT1 rescued the K(+) -uptake-defective phenotype of yeast strain CY162,

277 s also are consistent with the idea that the K(+) channels are nucleation points for SNARE complex as

278 We found that the K-Ras anchor binds selected plasma membrane anionic lipi

279 Using the K/BxN autoimmune arthritis model, we elucidate a novel m

280 because they form a channel complex with the K(+) channel pore-forming subunit Kv4.3 in a subset of n

281 protein scaffold for preferential binding to K-Ras G12D.

282 in cortical state are selectively linked to K pathway spiking activity, whereas delta-frequency cort

283 s and H(+)-ATPase and with the tonoplast TPK K(+) channel.

284 licited papillomas and hematopoietic tumors, K-Ras(G12V) induced lung tumors and gastric lesions.

285 ptic NMDA receptors (eNMDARs) and the A-type K(+) current (IA ) influences the firing activity of hyp

286 S plasticity by selectively targeting M-type K(+) channels, which predominantly localize to the AIS a

287 of medium afterhyperpolarization and M-type K(+) currents were smaller, when compared to ethanol nai

288 ls in Australia, India, Singapore, Sweden, U.K., and U.S.

289 on-small-cell lung cancer patients, by using K-Means clustering to group patients based on esophageal

290 eport that one of the K-Ras splice variants, K-Ras4a, is subject to lysine fatty acylation, a previou

291 outward and inward K(+) currents shifted Veq K(+) consistent with K(+) accumulation or depletion, res

292 novel roles for bacterially derived vitamin K forms known as menaquinones in health and disease, whi

293 l assess the risk and benefit of non-vitamin K oral anticoagulants among patients at high risk for st

294 f vIL-6 with the ER membrane protein vitamin K epoxide reductase complex subunit 1 variant 2 (VKORC1v

295 Whether vitamin K supplementation can prevent and/or treat calciphylaxis

296 ng 907 patients with AF treated with vitamin K antagonists (3,865 patient-years), to assess CVEs, inc

297 Bleeding risk with vitamin K antagonists (VKAs) is closely related to the quality o

298 the aqueous solution-vapor interface, while K(+) does not.

299 ity on data from dialysis patients, in whom [K(+)] varies significantly during the therapy.

300 +) currents shifted Veq K(+) consistent with K(+) accumulation or depletion, respectively, in the ext

301 ta from activated microglia, consistent with K(+) loss being needed for inflammasome assembly.