ライフサイエンスコーパス: KO mice

1 d lymphocytes in CD-fed, but not WD-fed, FXR KO mice.

2 ox and MOR-Nav1.8 sensory neuron conditional KO mice.

3 inputs on to these neurons in neonatal Fmr1 KO mice.

4 orptive state were comparable for the WT and KO mice.

5 and mucus production in allergen-treated ST2 KO mice.

6 otor behavior was not maintained in WAVE1 D1-KO mice.

7 on IL-10 secreting B cells was lower in VDR KO mice.

8 adiponectin level compared with that in ApoE-KO mice.

9 n of wild-type mice but not in those of 3MST-KO mice.

10 ed in both MG and conjunctiva of betaENaC MG KO mice.

11 cannot effectively activate RyR1 from Tric-a KO mice.

12 Protection by RvD2 was abolished in DRV2-KO mice.

13 ivation in latently HSV-1-infected IFN-gamma-KO mice.

14 tumor immunity in miR-155 T cell-conditional KO mice.

15 in Reelin-deficient or VLDLR/ ApoER2 double-KO mice.

16 n of cytokines and chemokines in WT and TLR4-KO mice.

17 revealed no differences between WT and PAK4 KO mice.

18 nificant differences between control and Hdc KO mice.

19 gnificantly ameliorated in Runx2 (Agc1CreER) KO mice.

20 ta-cells of control mice but not of betaGC-A-KO mice.

21 t of invasive prostate cancer in Pten single KO mice.

22 levels increased after exercise only in ATF3-KO mice.

23 he TRAF6[L74H] mice was normal, unlike TRAF6 KO mice.

24 ed in septic WT mice, but not in septic CIRP KO mice.

25 dant targets were significantly increased in KO mice.

26 c WT mice and significantly blunted in TRPC5 KO mice.

27 ndrial sirtuins was reduced in livers of the KO mice.

28 nucleus, are reduced in neurons from densin KO mice.

29 diaphragm protein was down regulated in pGR KO mice.

30 loss of bone density in infected gp91(phox) KO mice.

31 suppress glutamate release were seen in Fmr1-KO mice.

32 ivity that was largely absent in the P2X-dbl KO mice.

33 hage cytokines, including IL-1beta, in SIRT3 KO mice.

34 vior using a viral rescue approach in TRIP8b KO mice.

35 and ameliorates cognitive defects in IL-1R8 KO mice.

36 ndexes of mucin concentration in betaENaC MG KO mice.

37 had significantly more severe ALI than CIRP KO mice.

38 ause of decreased insulin secretion in A2AAR-KO mice.

39 significantly decreased in Runx2 (Agc1CreER) KO mice.

40 reduced features of steatohepatitis in MAT1A-KO mice.

41 e and hyperalgesia in WT mice but not in MOR KO mice.

42 r in WT mice, which was ameliorated in TRPC5 KO mice.

43 a raised serum IgE 4-fold in both WT and VDR KO mice.

44 WT mice, with a reduction observed in TRPC5 KO mice.

45 uld reduce hepatic lymphocytes in WD-fed FXR KO mice.

46 rse agonist, GR113808 in the PFC of CK2alpha KO mice.

47 mpaired motor function observed in the Zip14 KO mice.

48 decreased humoral immune response in Rictor KO mice.

49 d injury in previously untreated WT and TLR4-KO mice.

50 lar but less marked changes were seen in PrP KO mice.

51 ker stimulation in both young and adult Fmr1 KO mice.

52 nt murine CIRP, but not in the lungs of TLR4 KO mice.

53 inhibitory neurotransmission evident in Fmr1-KO mice.

54 pressant-like behavioral phenotype of TRIP8b KO mice.

55 re skeletal abnormalities than those of Cx43-KO mice.

56 n quadriceps of control mice but not in ATF3-KO mice.

57 cholinergic interneurons were normal in Hdc KO mice.

58 ides and phospholipids, in WT, but not TRPC5 KO mice.

59 hanced the survival of tumor-bearing CLEC14A-KO mice.

60 nd endothelial integrity in 6 week-old Cd2ap-KO mice.

61 ulated autophagy in the BAT of Gja1 (adipoq) KO mice.

62 acy of LY2828360 was absent in CB2 knockout (KO) mice.

63 berculosis infection, using IL-21R knockout (KO) mice.

64 n of NMDARs, we also analyzed PrP knock-out (KO) mice.

65 ces from wild-type and connexin 36-knockout (KO) mice.

66 and typically preceding cataplexy in Hcrt(ko/ko) mice.

67 mostasis and thrombosis, using APP knockout (KO) mice.

68 e blind" P2X2 /P2X3 double knockout (P2X-dbl KO) mice.

69 oles using global and conditional knock-out (KO) mice.

70 , we examined murine ortholog Nat1 knockout (KO) mice.

71 assessed in IL-15-deficient (IL-15 knockout, KO) mice.

72 ralgesia in wild type (WT) and MOR knockout (KO) mice.

73 c disease in Apolipoprotein (Apo)E knockout (KO) mice.

74 in mid-aged (>10-month-old) PV-knock out (PV-KO) mice.

75 affect hepatic inflammation in FXR knockout (KO) mice.

76 etic preganglionic neurons of Cx36-knockout (KO) mice.

77 d in the inflamed colons of AKAP12 knockout (KO) mice.

78 ytotoxic T cells (CD8+) in the p65 knockout (KO) mice.

79 ed podocyte-specific Shp2 knockout (pod-Shp2 KO) mice.

80 B6.B10ScN-Tlr4(lps-del)/JthJ [TLR4-knockout (KO)] mice.

81 In older betaENaC MG KO mice (5 to 11 months), significant ocular surface pat

82 we also observed in WT, but not in WAVE1 D1-KO mice, a decrease in dendritic spine density and a dec

83 from somatosensory cortex of Fmr1 knock-out (KO) mice, a model of Fragile-X Syndrome, to test the E/I

84 heart, we took advantage of MEF2A knock-out (KO) mice, a model that displays a predominantly ventricu

85 In Pml knock-out (KO) mice, ablation of Pml largely reduces IFNalpha angio

86 Adult Fmr1 KO mice actively avoided a stimulus that was innocuous t

87 In the apolipoprotein E-knockout (ApoE-KO) mice, adiponectin and T-cadherin colocalized on endo

88 also found in the cerebral cortex of Malat1 KO mice after ischemic stroke compared with WT controls.

89 Full survival of the treated KO mice, along with a positive impact on metabolite leve

90 voked potentials (VsEPs) in alpha9 knockout (KO) mice, alpha10 KO mice, alpha7 KO mice, alpha9/10 and

91 VsEPs) in alpha9 knockout (KO) mice, alpha10 KO mice, alpha7 KO mice, alpha9/10 and alpha7/9 double K

92 knockout (KO) mice, alpha10 KO mice, alpha7 KO mice, alpha9/10 and alpha7/9 double KO mice, and wild

93 Il28ra(-/-) and Stat1IEC-KO mice also developed more severe colitis in response t

94 Nat1 KO mice also displayed reduced whole-body energy expendi

95 veness was increased in allergen-treated ST2 KO mice and comparable with that in allergen-treated wil

96 ocytes to 1% of the control level, Podo-GC-A KO mice and control littermates did not differ in BP, GF

97 pertension of similar magnitude in Podo-GC-A KO mice and controls.

98 hosphate-N-acetylneuraminic acid hydroxylase KO mice and exhibited in vitro normal insulin secretion

99 Early onset profound hearing loss in KO mice and lack of information about the cochlear cell

100 affecting LMA; these effects were absent in KO mice and potentiated in OE mice.

101 Finally, the lean phenotype of Ati-CB1-KO mice and the increase in alternatively activated macr

102 rsened glucose tolerance in AgRP and POMC IR KO mice and their respective controls but increased hepa

103 We generated HSC-specific NOX4 KO mice and these were pair-fed on alcohol diet.

104 henotype of BgnFmod double knockout (BgnFmod KO) mice and found they were smaller in size and have ma

105 eloid cell-specific Nrp1-knockout (Nrp1(myel-KO)) mice and applied 2 stringent animal models of sepsi

106 nd LPA2-KO mice but not from LPA1-KO or COX1-KO mice, and PTX blocked this effect.

107 n of the infarct border zone was impaired in KO mice, and the animals developed larger infarct scars

108 stently, mGluR-LTD was impaired in calpain-1 KO mice, and the impairment could be rescued by phosphat

109 effect was blunted in beta-cells of betaGC-A-KO mice, and the maximal cytosolic Ca(2+) concentration

110 lpha7 KO mice, alpha9/10 and alpha7/9 double KO mice, and wild-type (WT) controls.

111 hippocampal slices from calpain-1 knock-out (KO) mice, application of the mGluR agonist, DHPG, did no

112 Brucella DNA colocalizes with AIM2, and AIM2 KO mice are less resistant to B. abortus infection.

113 l persulfurated species in the brain of 3MST-KO mice are less than 50% of that in the brain of wild-t

114 We find that RyR1 from Tric-a KO mice are more sensitive to inhibition by divalent cat

115 In line with this, Bap1 KO mice are more sensitive to tunicamycin-induced renal

116 Additionally, RyR1 from Tric-a KO mice are not activated by protein kinase A phosphoryl

117 Behaviorally, KO mice as well as mice with AAV-mediated deletion of CK

118 n the observed osteopenic phenotype of TIEG1 KO mice as well as the known links between TIEG1 express

119 w restriction in the inferior vena cava, APP-KO mice, as well as chimeric mice with selective deficie

120 e lungs of wild-type (WT) and CIRP knockout (KO) mice at 20 h after induction of sepsis by cecal liga

121 ppearance during exercise was blunted in the KO mice because of a diminished glycogenolytic flux.

122 elease from TA of wild-type, TP-KO, and LPA2-KO mice but not from LPA1-KO or COX1-KO mice, and PTX bl

123 ed the expression of podocyte nephrin in APA-KO mice but not in wild-type controls.

124 nd BAT thermogenesis were diminished in UCP1 KO mice, but BAT (18)F-FDG uptake was fully retained.

125 found no difference between WT and Munc13-2 KO mice, but global and MC-specific Munc13-4 KO mice dev

126 Hcrt loss in Hcrt(ko/ko) mice causes impaired TDW maintenance in baseline wak

127 The direction of circuit alterations in Fmr1 KO mice changes across development.

128 Additionally, in alpha9 KO mice, chemotherapy-induced development of cold allody

129 In contrast to wild-type (WT) and WAVE1 D2-KO mice, cocaine-induced sensitized locomotor behavior w

130 significantly (by approximately 20%) in EHD4-KO mice compared to WT mice in baseline conditions, sugg

131 ter load was significantly increased in EHD4-KO mice compared to WT mice, and although EHD4-KO mice c

132 XIa (FXIa), but not FXIIa, was higher in APP-KO mice compared with controls.

133 mor growth was profoundly reduced in CLEC14A-KO mice compared with that seen in WT littermates, but t

134 tions in the blood of OVA-sensitized Cyp27b1-KO mice compared with wild-type littermates (+898 and +2

135 urfold to fivefold higher in brains of Zip14 KO mice compared with young adult wild-type mice.

136 differences in metabolites in the livers of KO mice, compared to WT and Het mice.

137 mice compared to WT mice, and although EHD4-KO mice concentrated their urine during 24-h water restr

138 hepatic triglyceride levels only in POMC IR KO mice, consistent with impaired lipolytic regulation r

139 atures of brain injury observed in the Zip14 KO mice demonstrates that normal ZIP14 function is an es

140 nist, normalized alcohol preference in EFhd2 KO mice, demonstrating an EFhd2-driven relationship betw

141 Adipose tissue-specific AnkB-KO mice develop obesity and progressive pancreatic islet

142 Clrn1 knockout (KO) mice develop hair cell defects by postnatal day 2 (P

143 e in achieved systolic BP, AngII-treated APA-KO mice developed a significant rise in albuminuria not

144 Vitamin D deficient, VDR KO, and B-VDR KO mice developed hyper-IgE, whereas T-VDR KO mice did n

145 Finally, DHHC7 KO mice developed hyperglycemia and glucose intolerance,

146 KO mice, but global and MC-specific Munc13-4 KO mice developed less hypothermia.

147 However, only Podo-GC-A KO mice developed massive albuminuria (controls: 35-fold

148 present study, we found that ALCAM knockout (KO) mice developed a more severe myelin oligodendrocyte

149 /-), Irf3(-/-)Irf7(-/-), as well as Stat1IEC-KO mice, developed more severe colitis after administrat

150 Accordingly, ClC-K2 KO mice did not exhibit the natriuretic response to furo

151 By contrast, Chn1KO/KO mice did not have DRS, and embryos displayed abducens

152 R KO mice developed hyper-IgE, whereas T-VDR KO mice did not.

153 Whereas normoxia-treated KO mice die from neurodegeneration at about 60 d, hypoxi

154 Upon return to normoxia, Ndufs4 KO mice die within days.

155 50% of M. tuberculosis H37Rv-infected IL-21R KO mice died in 6 mo compared with no deaths in infected

156 in WT littermates, but tumor-bearing CLEC14A-KO mice died sooner.

157 Both WT and KO mice discriminated between reward and no-reward lever

158 urons in the barrel cortex of BC1 knock out (KO) mice display larger excitatory postsynaptic currents

159 SIRT6 knockout (SIRT6-KO) mice display loss of muscle, fat and bone density, t

160 APP-KO mice displayed a shorter APTT, but not PT, when measu

161 Further, HFD-fed Nrp1(myel-KO) mice displayed accentuated insulin resistance, enhan

162 Hippocampal neurons from Mecp2 knockout (KO) mice do not show the characteristic homeostatic scal

163 Sspn knockout (Sspn(KO)) mice do not have heart defects, but Nkx2-5(+/-)/Ssp

164 control and nonhematopoietic DREAM knockout (KO) mice, DREAM KO control and hematopoietic DREAM KO mi

165 EFhd2 knockout (KO) mice drink more alcohol than controls and spontaneou

166 ynaptic connectivity of interneurons in Fmr1 KO mice during a critical period of cortical development

167 Impaired hepatic zinc uptake in Zip14 KO mice during ER stress coincides with greater expressi

168 cells and re-established mortality of IL-15 KO mice during septic shock.

169 Both alpha7 and alpha10 KO mice evidenced normal thresholds, decreased activatio

170 During retinal angiogenesis, KO mice exhibit a 50% decrease in endothelial filopodia

171 L2hgdh KO mice exhibit white matter abnormalities, extensive gl

172 Global HCN1(KO) mice exhibit reduced reaching accuracy and atypical

173 betaENaC MG KO mice exhibited a striking age-dependent, female-predo

174 Furthermore, calpain-1 KO mice exhibited impairment in fear memory extinction t

175 Following administration of LPS, pod-Shp2 KO mice exhibited lower proteinuria and blood urea nitro

176 urvival curves and organ pathology in Ndufs4 KO mice exposed to hypoxia or hyperoxia.

177 etween reward and no-reward levers; however, KO mice failed to discriminate based on relative quantit

178 taneous and visceral adipose tissue of TRPC1 KO mice fed a HF diet and exercised.

179 eloid cell-specific Nrp1 knockout (Nrp1(myel-KO)) mice fed an HFD (60% kcal) for 16 weeks.

180 sed to feed wild type (WT) and FXR knockout (KO) mice followed by phenotyping characterization as wel

181 Furthermore, treatment of the KO mice for 5 mo maintained the plasma metabolite balanc

182 intestinal inflammation and fully protected KO mice from carcinogenesis.

183 Hcrt(ko/ko) mice fully implement TDW when waking is enforced, bu

184 ease observed in skeletal muscle from Tric-a KO mice, further highlighting the importance of TRIC-A f

185 During fasting, the KO mice had a defect in fatty acid oxidation.

186 A2AAR-KO mice had decreased expression of the beta-cell-specif

187 M. tuberculosis-infected IL-21R KO mice had enhanced bacterial burden and reduced infilt

188 the lungs of M. tuberculosis-infected IL-21R KO mice had increased expression of T cell inhibitory re

189 Tumors in CLEC14A-KO mice had increased numbers of nonfunctional blood ves

190 itory effects on actin polymerization, HSPB7 KO mice had longer actin/thin filaments and developed ab

191 The KO mice had metabolic features of MNADK-deficient patien

192 Male WD-fed FXR KO mice had the most severe steatohepatitis.

193 Our data revealed that male WD-fed FXR KO mice had the most severe steatosis and highest hepati

194 ocampal neurons derived from Crmp4-knockout (KO) mice had increased dendritic branching, compared to

195 We generated KO mice harboring a transgene, TgAC1, consisting of Clrn

196 Panx3-knockout (KO) mice have more severe skeletal abnormalities than th

197 Knockout (KO) mice have shown that RB plays roles in cell migratio

198 the osteoblasts and osteoclasts from BgnFmod KO mice having higher differentiation potential and bein

199 nd no differences between wild-type and Fmr1 KO mice in overall whisker-evoked activity, though 45% f

200 Both Tie2-CreNox2 knockout (KO) mice (in which Nox2 was deficient in both endothelia

201 In NIS KO mice, in the thyroid, stomach, and salivary gland, NI

202 ce harboring simple steatosis and CD-fed FXR KO mice, in which the steatosis had a potential to devel

203 A phenotypic analysis of Panx3-KO mice indicates that Panx3 regulates the terminal diff

204 creased in Tg(CJD) mice but decreased in PrP KO mice, indicating divergent changes in hippocampal syn

205 lin resistance and inflammation in Nrp1(myel-KO) mice, indicating that Nrp1 reduction in macrophages

206 GSNOR knockout (KO) mice infected with Plasmodium berghei ANKA had signi

207 IL-17C+KO mice initially exhibited decreased skin inflammation;

208 Moreover, BALB/c APA-knockout (KO) mice injected with a nephrotoxic serum showed persis

209 ensity of MR images from brains of the Zip14 KO mice is indicative of major manganese accumulation.

210 The skeletal muscle of Tric-a knockout (KO) mice is characterized by Ca(2+) overloaded and swoll

211 cts in hippocampus and cortex seen in double-KO mice lacking ITSN1 and ApoER2.

212 Knockout (KO) mice lacking ITSN1 suffer from dispersion of pyramid

213 P2X-dbl KO mice, like wild-type mice, did exhibit acid-induced c

214 Nat1 KO mice manifested whole-body insulin resistance, which

215 one-specific conditional PKD1-knockout (PKD1-KO) mice models.

216 adhesion were altered in the brain of Crmp4-KO mice, mostly in a gender-dependent manner.

217 1a/tm1a) ), floxed (Myo10 (tm1c/tm1c) ), and KO mice (Myo10 (tm1d/tm1d) ).

218 Like ErbB4 KO mice, NRG2 KOs performed abnormally in a battery of b

219 didymal white adipose tissue (eWAT) of PDE3B KO mice on a SvJ129 background, cAMP/protein kinase A (P

220 We generated MNADK knockout (KO) mice on a C57BL/6NTac background; mice with a wild-t

221 whisker stimulation in young Fmr1 knock-out (KO) mice (postnatal days 14-16), a model of FXS.

222 APP-KO mice presented a higher number of circulating platele

223 Moreover, Malat1 KO mice presented larger brain infarct size, worsened ne

224 IL-17 receptor C and Pten double KO mice recapitulated the weak EMT characteristics obser

225 Gja1 (adipoq) KO mice reduced mitochondrial density and increased the

226 We find that RyR1 channels from Tric-a KO mice respond normally to cytosolic Ca(2+) , ATP, aden

227 We find that whereas Hcrt(ko/ko) mice respond to 6-h sleep deprivation (SD) with a sl

228 vity, though 45% fewer neurons in young Fmr1 KO mice responded in a time-locked manner.

229 otypic characterization of unimmunized ALCAM KO mice revealed a reduced expression of BBB junctional

230 Telemetric analysis from conscious Cx36 KO mice revealed higher variance in heart rate and blood

231 Only infected gp91(phox) KO mice revealed significant loss of alveolar bone volum

232 ved from trkB.T1(+/+) (WT) and trkB.T1(-/-) (KO) mice revealed downregulation of migration and prolif

233 Experiments using HDAC11 knockout (KO) mice revealed that T cells from these mice displayed

234 ic lymph node cultures from VDR KO and B-VDR KO mice secreted higher IgE ex vivo than wild-type (WT)

235 Of note, BC1 KO mice show aberrant structural plasticity in response

236 We previously found that GABAB(1a) KO mice show generalized fear to a neutral context 24 h

237 ER stress-induced Zip14 KO mice show greater levels of hepatic steatosis due to

238 physiology, because both C57BL/6J and Pde11a KO mice show increased expression of the pro-inflammator

239 We show that muscle cells of syndapin III KO mice show severe reductions of caveolae reminiscent o

240 Fmr1 KO mice showed a greatly enhanced excitatory synaptic in

241 ce, DREAM KO control and hematopoietic DREAM KO mice showed a significant delay in time to occlusion.

242 In line with this, Shisa7 KO mice showed a specific deficit in contextual fear mem

243 Compared with controls, Ati-CB1-KO mice showed decreased body weight, reduced total adip

244 Crmp4-KO mice showed decreased social interaction and several

245 SIRT6-KO mice showed degenerated skeletal muscle phenotype wit

246 In open field test Hdc KO mice showed impaired exploratory activity and habitua

247 IL-15 KO mice showed improved survival, attenuated hypothermia

248 Emc10 KO mice showed no cardiovascular phenotype at baseline.

249 After SCI, astrocyte-specific trkB.T1 KO mice showed reduced hyperpathic responses and improve

250 Shisa7 KO mice showed reduced initiation and maintenance of lon

251 NIS KO mice showed undetectable serum T4 and very low serum

252 filament phenotype of HSPB7 KOs, but double KO mice still exhibited formation of abnormal actin bund

253 analysis of tubules isolated from knockout (KO) mice suggested that ClC-K2 is the main basolateral c

254 ation within atherosclerotic plaques of ApoE KO mice, suggesting plaque stabilization.

255 blood of sensitized T cell-specific Cyp27b1-KO mice support a lymphocyte-driven mechanism.

256 d (cxcl)13 were higher in quadriceps of ATF3-KO mice than in control mice.

257 these changes were more severe in male Crmp4-KO mice than in females.

258 murine oral cavities of infected gp91(phox) KO mice than in those of iNOS KO and C57BL/6 mice.

259 stological damage were more severe in AKAP12 KO mice than in WT mice.

260 hages in inflamed colons was lower in AKAP12 KO mice than in WT mice.

261 tion of the inflammatory signature in IL-17C+KO mice that aligns closely with human psoriasis.

262 metabolomic signature associated with MAT1A-KO mice that also was present in 49% of the patients; ba

263 Myo10 KO mice that survive birth can breed and produce litters

264 All Myo10 KO mice that survive birth exhibit a white belly spot, a

265 g glucose concentrations were lower in TRPC1 KO mice that were fed a high-fat (HF) (45% fat) diet and

266 deregulation in the mPFC that prevents Ophn1 KO mice to exploit a correctly acquired rule.

267 s study used B cell-specfic Rictor knockout (KO) mice to investigate how Rictor regulates BCR signali

268 Persistence of experimental asthma in ST2 KO mice was associated with an increase in levels of thy

269 The absence of OIH in MOR KO mice was found in both sexes, in two KO global mutant

270 Behavior of Hdc knock-out (Hdc KO) mice was assessed in an open field test.

271 In Il1rapl1-KO mice we identified an increased number of dendrite br

272 using primary neuronal cultures and Il1rapl1-KO mice, we characterized the role of IL1RAPL1 in regula

273 Moreover, using liver-specific TRbeta1-KO mice, we demonstrate that hypothyroidism-associated c

274 Using TLR4 knockout (TLR4.KO) mice, we show that TLR4 plays a role in NAc synaptic

275 MAT1A-KO mice were also given SAMe (30 mg/kg/day for 8 weeks);

276 ortical morphology and layering in adult Hdc KO mice were also preserved.

277 patic stellate cells (HSCs) from WT and TLR4-KO mice were assessed in vitro.

278 Livers of MAT1A-KO mice were characterized by high levels of triglycerid

279 Tg(CJD) but not PrP KO mice were intrinsically more susceptible than WT cont

280 GBP(chr3) but not GBP2 KO mice were more susceptible to bacterial infection, an

281 Wildtype, Ucp1-KO and Fgf21-KO mice were placed on control and low protein (LP) diet

282 mory and LTP is dependent upon APP since APP-KO mice were resistant to oAbeta- and oTau-induced defec

283 T cells from M. tuberculosis-infected IL-21R KO mice were unable to induce optimal macrophage respons

284 PAK4 knock-out (KO) mice were born at Mendelian ratios in both genders.

285 Wild-type (WT) and TRPC5 knock-out (KO) mice were fed a diet supplemented with 0.5% cholic a

286 Apolipoprotein E knockout (ApoE-KO) mice were infused with angiotensin II (AngII) for 28

287 IF1 knockout (KO) mice were protected against cardiac dysfunction and

288 ndria from wild-type (WT) and CypD knockout (KO) mice were treated to either stimulate OXPHOS or open

289 In this study, newborn CBS-knockout (KO) mice were treated with recombinant polyethyleneglyco

290 sults reveal that hungry mice lacking GPR88 (KO mice) were slow to acquire food-reinforced lever pres

291 twork that were down-regulated in the Nkx2.2(KO) mice, were maintained in the Nkx2.2( big up tri, ope

292 n, adoptive transfer of WT platelets to CD40-KO mice, which are resistant to experimental cerebral ma

293 transfer of wild-type (WT) platelets to CD40-KO mice, which do not control parasite replication, resu

294 , which cannot interact with the TR, in Pax8-KO mice, which make no thyroid hormone.

295 fat diet-induced ER stress using Zip14(-/-) (KO) mice, which exhibit impaired hepatic zinc uptake.

296 onine adenosyltransferase 1a knockout (MAT1A-KO) mice, which have chronically low levels of hepatic S

297 used, and high salt-fed (ALDO) systemic GC-A KO mice with enhanced phosphorylation of p38 mitogen-act

298 metabolomes of patients with NAFLD and MAT1A-KO mice with steatohepatitis, we identified 2 major subt

299 Transplanting KO mice with wild-type bone marrow cells rescued the ang

300 Podocyte-specific Pkm2-knockout (KO) mice with diabetes developed worse albuminuria and g