1 o devastating multi-system syndromes such as Kearns-Sayre syndrome.

2  of mitochondrial DNA (mtDNA) cause sporadic Kearns-Sayre syndrome, a fatal multisystem disorder, in

3 ciated with three major clinical conditions: Kearns-Sayre syndrome, a multisystem disorder; Pearson s

4 Since most mtDNA-related diseases, including Kearns-Sayre syndrome, are recessive, only a few wild-ty

5 aled a 2,532-bp deletion of the type seen in Kearns-Sayre syndrome as well as a heteroplasmic A3243G

6         A 35-year-old woman with features of Kearns-Sayre syndrome consisting of progressive ptosis,

7 rs characterised by a complex phenotype; the Kearns-Sayre syndrome, for example, can include cardiac

8              Mitochondria from patients with Kearns-Sayre syndrome harboring large-scale rearrangemen

9                                 For example, Kearns-Sayre syndrome is caused by a single heteroplasmi

10                                              Kearns-Sayre syndrome (KSS) is a sporadic multisystem di

11 hronic progressive external ophthalmoplegia, Kearns Sayre syndrome, or Pearson's syndrome.