ライフサイエンスコーパス: L

1 773 g/L compared with 8.04 g/L; IQR: 0.449 g/L).

2 ypophosphataemia (serum phosphate < 0.6 mmol/L).

3 lasma TMAO was 3.05 mumol/L (2.10-4.60 mumol/L).

4 chlor (6-230 ng/L), and terbutryn (29-810 ng/L).

5 t caproate concentration of 11.44 +/- 0.47 g/L.

6 ic mean of 25OHD concentration was 66.8 nmol/L.

7 a severe disease of wheat (Triticum aestivum L.).

8 mol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

9 mol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

10 nd the accompanying "dormant" structures T(1)L(1) and T(2)L(2) and nicking enzyme Nt.BbvCI, undergoes

11 ion plot LODs were calculated to be 0.032 ug L(-1) (Cd(II)) and 0.015 ug L(-1) (Pb(II)) for A-MWCNT/H

12 I)) for A-MWCNT/Hyalu/l-Cys/GCE and 0.057 ug L(-1) (Cd(II)) and 0.034 ug L(-1) (Pb(II)) for A-MWCNT/H

13 d to be 0.032 ug L(-1) (Cd(II)) and 0.015 ug L(-1) (Pb(II)) for A-MWCNT/Hyalu/l-Cys/GCE and 0.057 ug

14 GCE and 0.057 ug L(-1) (Cd(II)) and 0.034 ug L(-1) (Pb(II)) for A-MWCNT/Hyalu/l-Ser/GCE.

15 thin detection ranges of 0-100 and 0-50 mmol L(-1) , and selectivities of 15.6 and 8.1 mmol L(-1) , r

16 -1) , and selectivities of 15.6 and 8.1 mmol L(-1) , respectively.

17 fructose with limits of detection of 0.012 g L(-1) and 0.010 g L(-1), respectively.

18 alibration curve was linear from 0.1 to 15 g L(-1) for glucose and fructose with limits of detection

19 Overall, 100 umol L(-1) MeSA was the most effective for maintaining fruit

20 ted within 4 days, reaching up to 100-200 mg.L(-1) of dissolved sulfide produced after 19-24 days, de

21 as tested with tap water spiked with 0.11 mg L(-1) of nine different HAAs in a similar reduction expe

22 ere calculated as 0.13 mug L(-1)and 0.41 mug L(-1) respectively.

23 at two concentration levels of 25 and 250 ug L(-1) varied between 4.2 and 9.5%.

24 easured at a concentration level of 7-10 mug L(-1) were in good agreement with those obtained using t

25 .997, Cu = 0.506, Zn = 4.15 and I = 0.458 mg L(-1)) and mothers of full-term (Fe = 0.733, Cu = 0.234,

26 .733, Cu = 0.234, Zn = 2.91 and I = 0.255 mg L(-1)) infants.

27 ts of detection of 0.012 g L(-1) and 0.010 g L(-1), respectively.

28 l method at a concentration level of 150 mug L(-1).

29 tification (LOQ) were calculated as 0.13 mug L(-1)and 0.41 mug L(-1) respectively.

30 sensitivity C-reactive protein level, 2.1 mg/L), 12 633 (96.6%) completed the trial with ascertainmen

31 , and a C-reactive protein level of 203.8 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/

32 , and a C-reactive protein level of 203.8 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/

33 concentration of plasma TMAO was 3.05 mumol/L (2.10-4.60 mumol/L).

34 anying "dormant" structures T(1)L(1) and T(2)L(2) and nicking enzyme Nt.BbvCI, undergoes dissipative

35 Using the P L(2,3)-edge, we identified different organic P species,

36 ee oncometabolites - fumarate, succinate and L-2-HG - have been implicated in this disease process.

37 er, [K(2.2.2-cryptand)][(tBu) LNi(S)] ((tBu) L={(2,6-(i) Pr(2) C(6) H(3) )NC((t) Bu)}(2) CH).

38 , [K(2.2.2-cryptand)][(Me) LZn(S)] (2) ((Me) L={(2,6-(i) Pr(2) C(6) H(3) )NC(Me)}(2) CH), was isolate

39 croinjection (at RAIC) of the following: (1) L-368899 (an oxytocin receptor [OTR] antagonist) or by (

40 ddition, virus-encoded VP3 antagonizes RNase L activity both in vitro and in vivo These studies highl

41 ) 55 is a putative cannabinoid receptor, and l-alpha-lysophosphatidylinositol (LPI) is its only known

42 ransporter-mediated histidine uptake, system L amino acid transporter activity and Na(+) K(+) -ATPase

43 al range, 4.0-10.0 x 103/muL [4.0-10.0 x 109/L]), an elevated sedimentation rate of 100 mm per hour (

44 range, 4.0-10.0 x 10(3)/uL [4.0-10.0 x 10(9)/L]), an elevated sedimentation rate of 100 mm per hour (

45 apolipoproteins B and A-I were 1.03 (0.24) g/L and 1.54 (0.27) g/L, respectively.

46 ns were notable: t-tau 8 to 16 years, and Nf-L and GFAP 4 to 8 years prior to clinical AD.

47 g/L was as effective as a threshold of 90 g/L and resulted in similar HRQOL and HCT outcomes with fe

48 tivity (urine LOD = 0.023 g/L, LOQ = 0.075 g/L) and over a broad range of physiologically relevant co

49 The sensitivities of CRP (cut-off 6.5 mg/L) and PCT (cut-off 0.025 ng/mL) were 52.3% (36.7-67.5%,

50 nding tissue, due to linkage disequilibrium (LD) and the correlation of gene expression between tissu

51 coprop (98-5300 ng/L), metolachlor (6-230 ng/L), and terbutryn (29-810 ng/L).

52 nts/L)-, GR (60 ng dexamethasone equivalents/L)-, and PPARgamma-mediated activities were detected at

53 tion by two staple crops, rice (Oryza sativa L.) and wheat (Triticum aestivum L.), and evaluates pote

54 ryza sativa L.) and wheat (Triticum aestivum L.), and evaluates potential risks associated with their

55 flowers of Tilia cordata Mill, T.x europaea L., and T. platyphyllos Scop.

56 n tea extract at 10 (GWG1%) and 50 (GWG5%) g/L as the steeping solution on the chemical, nutritional,

57 Using dill (Anethum graveolens L.) as a model herb, we reveal novel associations betwee

58 en made with the studies reported earlier in l-ascorbic acid, thiamine HCl and pyridoxine HCl.

59 caused in part by the use of l-asparaginase (L-ASP).

60 for thrombosis, caused in part by the use of l-asparaginase (L-ASP).

61 which is exported by DcuABC in exchange for L-aspartate and L-malate.

62 L-AZM use resulted in a remarkable decrease in cardiac i

63 These catalysts have low linear-to-branched (L:B) regioselectivity for simple linear alkenes.

64 in the phenolic fraction of Theobroma Cacao L. beans.

65 treatment of 133 patients with CL caused by L. braziliensis in Bahia, Brazil.

66 identified a HLA region associated with NMO, led by rs9272219 (OR = 2.48, P = 8 x 10(-10)).

67 olescent Asthma Action) programme and a peer-led camp based on the Power Breathing Programme.

68 The true population LD cannot be measured directly and instead can only be i

69 -weighted average concentration: 250-4800 ng/L), carbamazepine (33-910 ng/L), diclofenac (78-1000 ng/

70 zepine (33-910 ng/L), diclofenac (78-1000 ng/L), carbendazim (21-900 ng/L), diazinon (2.1-53 ng/L), d

71 membrane tubules in hepatoma cells and along LD-centric autophagic membranes.

72 Although generic language always led children to believe that properties were nonaccident

73 d to be 8.8 ng/L with sensitivity 0.41 mA/ng/L/cm(2) for chlorpyrifos (CPF); and 10.2 ng/L with sensi

74 ); and 10.2 ng/L with sensitivity 0.58 mA/ng/L/cm(2) for methyl parathion (MP).

75 s than nonsecretors (11.45 g/L; IQR: 0.773 g/L compared with 8.04 g/L; IQR: 0.449 g/L).

76 cal Society, set up an international, expert-led consensus project to develop evidence- and experienc

77 in healthy and BS berries in Vitis vinifera L. cultivar Blauer Zweigelt.

78 Sugarcane (Saccharum officinarum L.) cultivation leaves behind around 20 t ha(-1) of biom

79 nd 0.015 ug L(-1) (Pb(II)) for A-MWCNT/Hyalu/l-Cys/GCE and 0.057 ug L(-1) (Cd(II)) and 0.034 ug L(-1)

80 ) was previously proposed to oxidize S-allyl-l-cysteine (SAC) to alliin, an allicin precursor.

81 was highly active with l-cysteine, N-acetyl-l-cysteine, and allyl mercaptan.

82 ; however, the enzyme was highly active with l-cysteine, N-acetyl-l-cysteine, and allyl mercaptan.

83 ere hypersensitive to short active (SA; 19:5 L:D) photoperiod exposure versus their wildtype (WT) lit

84 hat was significantly associated with a 0.12-L decrease in the lung volume of exhaled air (95% confid

85 fenac (78-1000 ng/L), carbendazim (21-900 ng/L), diazinon (2.1-53 ng/L), diuron (22-1100 ng/L), mecop

86 on: 250-4800 ng/L), carbamazepine (33-910 ng/L), diclofenac (78-1000 ng/L), carbendazim (21-900 ng/L)

87 rbendazim (21-900 ng/L), diazinon (2.1-53 ng/L), diuron (22-1100 ng/L), mecoprop (98-5300 ng/L), meto

88 sts that up to two-thirds at risk to inherit LS don't participate.

89 vealed attenuated directed exploration under L-dopa, while neural signatures of exploration, exploita

90 We additionally determined that in l-DOPA-naive rats striatal rAAV-Nurr1 overexpression (1)

91 n hinges that become less constrained in the LD environment.

92 pathogenesis is preserved between V-EoE and L-EoE.

93 Yang P, Zhang Y, Zhang L, et al.

94 Embryos exposed to 10 and 50 mug/L fluoxetine were able to reduce fluoxetine accumulation

95 mg/m(2) administered intravenously over 2 h, l-folinic acid (175 mg flat dose administered intravenou

96 se administered intravenously over 2 h) or d,l-folinic acid (350 mg flat dose administered intravenou

97 ddition to wine required high doses (25-32 g/L) for protein removal and haze prevention and this indu

98 ing intramuscular immunisation, GBS67-CpGODN+L formed a vaccine depot at the injection site and induc

99 At this l-fucose dose, complement activation and acute post-isch

100 Salmonella as well as to the monosaccharides l-fucose, d-mannose, N-acetylglucosamine, N-acetylgalact

101 dlich adsorption coefficients of 156 and 629 L/g(-n), respectively.

102 g that HFOs are generated locally within the LS GABAergic population.

103 mutant affected in theVTC2 gene encoding GDP-l-Gal phosphorylase, which catalyzes the first committed

104 , the methods of Marfey and Mosher indicated l-Glu, l-Ile, l-Phe and 1S-configurations, respectively;

105 Interestingly, both l-glucose-derived ligands are partial agonists: they are

106 vitro ER (24 ng 17beta-estradiol equivalents/L)-, GR (60 ng dexamethasone equivalents/L)-, and PPARga

107 richness will alter sorghum (Sorghum bicolor L.) growth, soil nutrient dynamics and interactions (ant

108 is, suggest that the two carbon atoms of the L->C(2) complex both have carbene character.

109 ed, although a predicted helix-loop-helix (H-L-H) was suggested to form pores by virtue of its simila

110 found that Zr-MOF-808 can produce up to 8.66 L(H2O) kg(-1)(MOF) day(-1), an extraordinary finding tha

111 al ethanol yield range from 279.5 to 3,101.2 L ha(-1) across accession with an average of 1,266.3 L h

112 across accession with an average of 1,266.3 L ha(-1) which is significantly higher than values repor

113 To date, a binding site for P on L had not been described.

114 ein, heterogeneous nuclear ribonucleoprotein-L (hnRNPL).

115 fections among inpatients and outpatients at l'Hopital Gabriel Toure, the main source of pediatric te

116 a frame-shift insertion affecting the alpha-L-iduronidase (IDUA) gene (c.19_20insCGGCCCCC), a mutati

117 ethods of Marfey and Mosher indicated l-Glu, l-Ile, l-Phe and 1S-configurations, respectively; ROESY

118 relative to the pre-oral great appendages of L. illecebrosa indicates that these limbs correspond to

119 entrations (maximum 448 ng/g in soil, 3.4 mg/L in groundwater).

120 lower-target group and 106 mg/dL (2.72 mmol/L) in the higher-target group.

121 DL-C concentrations were 64 mg/dL (1.64 mmol/L) in the lower-target group and 106 mg/dL (2.72 mmol/L)

122 uids as a function of the confinement length L, in agreement with experimental results, and provides

123 ial oil constituents of Hyssopus officinalis L. in two successive harvests.

124 exhibits altered fluorescence in response to LD interactions with the lysosome.

125 The peer-led interventions included the Triple A (Adolescent Asth

126 L (IQR: 12-98), P < 0.01), lactate [1.1 mmol/L (IQR: 1.0-1.6) vs 4.6 mmol/L (IQR: 2.8-8.0), P < 0.01]

127 ive protein [138 mg/L (IQR: 83-179) vs 73 mg/L (IQR: 12-98), P < 0.01), lactate [1.1 mmol/L (IQR: 1.0

128 ctate [1.1 mmol/L (IQR: 1.0-1.6) vs 4.6 mmol/L (IQR: 2.8-8.0), P < 0.01], and fraction of inspired ox

129 Median C-reactive protein [138 mg/L (IQR: 83-179) vs 73 mg/L (IQR: 12-98), P < 0.01), lact

130 .45 g/L; IQR: 0.773 g/L compared with 8.04 g/L; IQR: 0.449 g/L).

131 oligosaccharides than nonsecretors (11.45 g/L; IQR: 0.773 g/L compared with 8.04 g/L; IQR: 0.449 g/L

132 s localized within distinct motile puncta in L. japonicus root hairs and in Nicotiana benthamiana lea

133 68%), living-donor kidney transplant alone (LD-KA, 30%), or SPK (2%).

134 Ruth L Kirschstein Research Service Award, American Society o

135 , we discovered and validated the plasmodial l-lactate transporter, PfFNT, as a novel antimalarial dr

136 biodegradable poly(ethylene glycol)-b-poly(d,l-lactide) (PEG-PDLLA) block copolymers, with the two bl

137 Mice fed the L lactis subsp cremoris had increased glucose tolerance

138 However, the presence of 50 g/L lactose reduced the RFP intensity due to lactose-induc

139 divided into three groups as follows: Group L (lesion) in which there is a furcal lesion with period

140 of leishmaniasis, immunize individuals with L. longipalpis salivary antigens LJM17 and LJM11.

141 h excellent sensitivity (urine LOD = 0.023 g/L, LOQ = 0.075 g/L) and over a broad range of physiologi

142 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

143 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

144 is achieved through a hydrophobic trimethyl-L-lysine-binding 'cage' formed by BAHCC1(BAH), mediating

145 ed by DcuABC in exchange for L-aspartate and L-malate.

146 ble immunodetection methods, we show that Nf-L measurement based on DPS microsampling is similar to t

147 These results suggest that LS measurement may be helpful to select candidates to be

148 , diazinon (2.1-53 ng/L), diuron (22-1100 ng/L), mecoprop (98-5300 ng/L), metolachlor (6-230 ng/L), a

149 complex that may have roles during the RNase L-mediated antiviral response.

150 diuron (22-1100 ng/L), mecoprop (98-5300 ng/L), metolachlor (6-230 ng/L), and terbutryn (29-810 ng/L

151 0.69 +/- 0.07 l min(-1) , P < 0.05) and muscle diffusive O(2) conducta

152 la infection blocked xenophagic targeting of L. monocytogenes by a RavZ-dependent mechanism.

153 ds to 1) promotion of cell-to-cell spread by L. monocytogenes, 2) defective leukocyte recruitment to

154 While l-morph individuals form flowers with long styles, short

155 Random allocation to LD-MTX (<=20 mg/wk) or placebo.

156 ive protein level of 203.8 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

157 ive protein level of 203.8 mg/L (1940.9 nmol/L) (normal range, <=10 mg/L [<=95.2 nmol/L]).

158 cell count of 15.1 x 10(3)/uL (15.1 x 10(9)/L) (normal range, 4.0-10.0 x 10(3)/uL [4.0-10.0 x 10(9)/

159 ood cell count of 15.1 x 103/muL (15.1 x 109/L) (normal range, 4.0-10.0 x 103/muL [4.0-10.0 x 109/L])

160 (210)Pb concentrations >= 1.0 pCi/L occurred most frequently where acidic groundwaters inh

161 Further 20 g/L of GSP added to the must induced less changes to wine

162 found using tert-butanol as a solvent, 20 g/L of lipase B from Candida Antarctica, and vinyl cinnama

163 ivars of sea buckthorn (Hippophae rhamnoides L.) of various ripening times.

164 yptophans that have lower free energy in the LD oil phase and positively charged residues near predic

165 = .019), C-reactive protein (198 vs. 107 mg/L, P = .010) and D-dimer (8.6 vs. 2.1 ug/mL, P = .004) l

166 Doublet chemotherapy was used in 36.4% of 2 L patients, most commonly fluoropyrimidine + irinotecan.

167 of Marfey and Mosher indicated l-Glu, l-Ile, l-Phe and 1S-configurations, respectively; ROESY correla

168 However, without competitors, L. picturatus survival was greater at high-elevation tha

169 miR-125a-5p and L-plastin may be relevant targets for increasing in vitr

170 ation of leukocyte and platelet-rich fibrin (L-PRF) + autogenous bone graft (ABG) may be a clinically

171 al Delphi survey represents the first expert-led process for developing a standardized approach for e

172 ys1 knockdown is a powerful means to prevent LD progression, but this approach did not reduce brain g

173 gether, these observations reveal that RNase L promotes the formation of a unique RNP complex that ma

174 ion of AL with LT (r = -0.137; P = .002) and LD (r = 0.268; P < .001), it was not significant with LV

175 e, or coronary revascularisation) per 1 mmol/L reduction in LDL cholesterol.

176 d A-I were 1.03 (0.24) g/L and 1.54 (0.27) g/L, respectively.

177 with a low-power blue light emitting diode (LED), resulting in local anesthesia.

178 e-species product B animalis subsp lactis or L reuteri significantly reduced duration of hospitalizat

179 synthetize the 2-OMe-alpha-l-Rha-(1->2)-beta-l-Rha fragment.

180 ivities needed to synthetize the 2-OMe-alpha-l-Rha-(1->2)-beta-l-Rha fragment.

181 m species), or Gynophilus LP vaginal tablet (L. rhamnosus 35) for two months.

182 +/- 1 kg m(-2) ) received primed continuous l-[ring-(2) H(5) ]phenylalanine before consuming a mixed

183 e hypothesize that one function of the P and L rings is to seal the outer membrane after motor disass

184 activity of EBV gH/gL and the EBV gH/gL-N(69)L/S(71)V mutant.

185 stallographic structure of Bacillus subtilis LS (SacB) in complex with a levan-type fructooligosaccha

186 tissues followed by linkage disequilibrium (LD) score-based enrichment testing for each trait.

187 nd 0.034 ug L(-1) (Pb(II)) for A-MWCNT/Hyalu/l-Ser/GCE.

188 first noted in the early 20(th) century and led some researchers to later question its value as a mo

189 ditionally used a fluorescent variant of the LD-specific protein (PLIN2) that exhibits altered fluore

190 c environment where patients underwent nurse-led structured evaluation (blood/urine/eye/feet) in publ

191 simulations and studies in cells reveal that LD targeting of these motifs requires deeply inserted tr

192 H) Scientific Workforce Diversity office has led the charge to develop and implement evidence-informe

193 Caffeine worsened and L-theanine had a trend of worsening inhibitory control (

194 clusters had 1118 eligible index cases that led to 342 interventions covering 8948 individuals.

195 Infection led to a 3-fold depletion of ILC3 in the colon and an in

196 nflammatory or neuropathic hyperexcitability led to a change in the temporal pattern of AP firing, em

197 Pharmaco- and optogenetic inhibition of MEC led to a disruption of border coding in RSC, but not vic

198 king temperatures in the winter of 2015/2016 led to a February onset of plant growth and the ecosyste

199 navirus disease 2019 (COVID-19) pandemic has led to a large increase in mortality in the United State

200 d that the presence of RBD near the membrane led to a local enrichment of anionic lipids that could p

201 Cyclosporine led to a more pronounced global transcriptome reversion

202 1/5/8 in the mouse submandibular glands, and led to a recovery of SG function and a decrease in infla

203 MMP1 expression led to a reduction in collagen 1A1 levels.

204 re, we found that the rd10 mutation in Pde6b led to a reduction in the assembled PDE6alphabetagamma2

205 (H)17 cell/IL23 signaling, whereas dupilumab led to a stronger increase in level of epidermal differe

206 compounds extracted by emerging technologies led to a sustainable alternative to control microorganis

207 tion of the TMEM189 gene in human HAP1 cells led to a total loss of plasmanylethanolamine desaturase

208 etastases and their response to therapy have led to adoption of some of these methods into routine cl

209 The gain in affinity led to almost equal inhibition of wildtype PfFNT and the

210 The rise in metagenomics has led to an exponential growth in virus discovery.

211 In our department, these circumstances led to an immediate restructuring of the working dynamic

212 ell culture conditions or in Balb/C mice and led to an over 2-fold increase in CTC attachment to ECs

213 constitutive activation of SARM1 and thereby led to axonal degeneration.

214 Systematic evaluations led to benzophenone-containing probes that efficiently a

215 Computational analysis revealed that reward led to both an increase in feedback correction in the mi

216 Seminal studies using squid as a model led to breakthroughs in neurobiology.

217 Interventions that led to changes in degree of AI and AS did not seem to in

218 5 mutant plants, loss of the ZmNLP5 function led to changes in expression for a significant number of

219 mpared with ceCT, (68)Ga-FAPI PET/CT results led to changes in TNM staging in 10 of 19 patients.

220 Likewise, Gas5 overexpression led to decreased cocaine intake, decreased motivation, a

221 t the organism level-a top-down approach-has led to definition of unifying properties, a hallmark of

222 compromising bipolar filament formation but led to divergent adhesion phenotypes and NMIIA contracti

223 at 4 degrees C, whereas the mutation of hapR led to fast entry into the VBNC state.

224 lture of MAIT cell supernatants with B cells led to greater tissue like memory B cell frequencies.

225 er IPA compared with chewed prasugrel, which led to higher active metabolite concentration but not gr

226 atically characterizing these algorithms has led to important insights, including the discovery of gu

227 lution of these procedures is unique and has led to improved vector delivery.

228 nic profile in several cases, and one design led to improvement of cross-neutralization of heterologo

229 re to e-cigarette aerosols in human subjects led to increased blood pressure and heart rate, similar

230 larization and tight junction breakdown, and led to inhibition of RPE65 expression, diminishment of R

231 treatment within 7 days after symptom onset led to lower 90-day mortality than use of placebo (relat

232 These features have led to many techniques for screening and diagnosis, but

233 This limitation has led to models of early life in which the first cells use

234 its C-terminal lysine residue; its deletion led to modest reductions in complement resistance.

235 asing human population, which has inevitably led to new biomedical and environmental issues.

236 al nearby tissue types in this data set also led to our identification of functional convergence in e

237 t of PHH with both HBV particles and Pam3Cys led to phosphorylation of ERK (extracellular signal-regu

238 ation costing an estimated $588 M (2016 USD) led to predicted pintail population sizes <3 M when assu

239 2 binding over tetramerization; this in turn led to preferred integration of single spacers over two

240 ion of Shank3 in vS1 inhibitory interneurons led to pyramidal neuron hyperactivity and increased stim

241 -CM and the advent of effective therapy have led to rapid adoption of diagnostic scintigraphy, there

242 Interference with U3 snoRNA expression led to reduction of rRNA levels and translational capaci

243 -type monocytes (~3-fold increase; P < 0.05) led to reductions in cerebral soluble amyloid-beta1-42,

244 Inflammatory challenge led to robust eGFP-L10a upregulation in kidney, confirmi

245 tree mortality concomitant with drought has led to short-term (mean 5 y, range 1 to 23 y after morta

246 for reforms of the research culture that has led to shortcomings in rigor.

247 Recent advances in molecular techniques have led to significant progress in the elucidation of the ro

248 Overexpression of Rig-G led to significantly reduced cell growth and suppressed

249 d extended longevity, and exposure to stress led to splicing and activation of xbp-1 in these neurons

250 Hippo pathway kinase LATS2, and this effect led to subsequent activation of oncogenic YAP.

251 es in the literature where this approach has led to substantial progress in understanding host-microb

252 This review explores the properties that led to such widespread use, why there is now an increasi

253 sis of bruceol, a pentacyclic meroterpenoid, led to the anticipation, isolation, and synthesis of iso

254 sleep disorders were the core symptoms that led to the description of this disease, whereas in anti-

255 synthesis and fabrication technologies have led to the development of integrated soft electronic dev

256 can be time-consuming and costly, which has led to the development of programmes for performing comp

257 se health effects in humans and wildlife has led to the development of scientific and regulatory appr

258 The hit-to-lead optimization led to the discovery of a novel chemotype series exempli

259 tency, selectivity, and oral bioavailability led to the discovery of the potent, highly selective, or

260 A strategic screening approach led to the discovery of this novel ligand, which was suc

261 The suppression of storage proteins led to the elaboration of membrane stacks enriched with

262 standing of the mechanisms underlying UC has led to the emergence of new treatments.

263 pressure to reduce reflected bioluminescence led to the evolution of ultra-black skin (reflectance <0

264 the best strategy was threshold-based, which led to the fewest infections of all strategies tested (9

265 Studying genome and epigenome led to the fundamentals of development and progression o

266 For topological reasons, this led to the generation of four defects in the resulting h

267 This work has led to the identification of new, unexplored genomic reg

268 This approach led to the identification of seven novel genetic causes

269 ency, selectivity, and ADME properties which led to the identification of the clinical candidate PF-0

270 -affinity receptor, plexinD1, on macrophages led to the improvement in clinical disease following exp

271 ven by a metabolic switch in Th17 cells that led to the induction of the amino acid starvation respon

272 This strategy led to the synthesis of new conformationally restrained

273 Global financial crises have led to the understanding that classical econometric mode

274 Widespread application of neonicotinoids has led to their proliferation in waters.

275 High doses of the initial lead compound led to tumor stasis in an activated B-cell-like (ABC) di

276 Switching mice to a high lysine/low PN diet led to vigorous seizures and a quick death in KO mice.

277 lared 2017 nuclear release of ruthenium that led to widespread detections of the radioisotope (106)Ru

278 quired substantially lower doses of GSP (5 g/L) to prevent haze formation.

279 hmaniasis (CL) caused by Leishmania tropica (L. tropica) represents a public health challenge in seve

280 L-Tryptophan is an essential amino acid required for pro

281 Ca(2+)-permeable AMPA receptor upregulation, L-type Ca(2+) channel activation, enhanced spine Ca(2+)

282 Only the L-type Ca(2+) current exhibits a day versus night differ

283 suggest that TSPAN-7 modulation of beta-cell L-type Ca(V) channels is a key determinant of beta-cell

284 potential (AP) prolongation (~50%), reduced L-type calcium channel (LCC) current (~33%), reduced out

285 A decrease in the L-type calcium influx is observed in both glutamatergic

286 through its N-terminal region, scaffolds the L-type pore-forming alpha1 subunit and, through its C-te

287 O-(2-(18)F-fluoroethyl)-l-tyrosine ((18)F-FET) (7 studies, 172 lesions) demonstr

288 is the key enzyme ensuring the conversion of l-tyrosine to dopaquinone, thereby initiating melanin sy

289 , we exposed Moina dubia to lead (Pb, 50 mug/L) under two temperatures (25 and 28 degrees C) with/wit

290 The highest L* value was measured in S-bread as 71.2, whereas it was

291 From 832 high-LD variants, we identify 39 candidate functional variant

292 e RBC transfusion strategy threshold of 70 g/L was as effective as a threshold of 90 g/L and resulted

293 P2 compared to P1 (AFS was 80% and 87% while LS was 64% and 72% in P2 and P1 respectively).

294 ombination alone and together with lecithin (L) were evaluated for their inhibition against the forma

295 tation-free survival (AFS) and Limb salvage (LS) were noticeably worse in P2 compared to P1 (AFS was

296 it of detection (LoD) was found to be 8.8 ng/L with sensitivity 0.41 mA/ng/L/cm(2) for chlorpyrifos (

297 /L/cm(2) for chlorpyrifos (CPF); and 10.2 ng/L with sensitivity 0.58 mA/ng/L/cm(2) for methyl parathi

298 median age, 69 y; median serum PSA, 3.69 mug/L) with 232 metastatic nodes less than 12 mm in diameter

299 5 orders of magnitude from 0.28 to 13 500 ng/L, with 38 compounds detected in >50% of samples.

300 n the lactate clearance to levels <=2.5 mmol/L within 4 h.

301 alues (9.9) and low DOC concentration (11 mg/L(-)) would maximize triclosan phototransformation rate