ライフサイエンスコーパス: L-lysine

1 slips coated with a cell adhesive film (poly(L-lysine)).

2 amide linkage to the epsilon-amino group of L-lysine.

3 lly distinct compounds, acriflavine and poly-l-lysine.

4 grown in the presence of L-arginine but not L-lysine.

5 cell contacts when cells were plated on poly-l-lysine.

6 back regulation and is strongly inhibited by l-lysine.

7 charomyces pombe HCS (SpHCS) in complex with l-lysine.

8 primary amine side chains of l-ornithine or l-lysine.

9 oglutarate and the epsilon-ammonium group of l-lysine.

10 as did the polycation PIP(2) scavenger poly-L-lysine.

11 sine analog N-epsilon-cyclopentyloxycarbonyl-l-lysine.

12 Pyl analog N-epsilon-cyclopentyloxycarbonyl-l-lysine.

13 e or of l-alanine and ethylamine in place of l-lysine.

14 ity functioning well on both L-ornithine and L-lysine.

15 mmobilized on a glass slide coated with poly-l-lysine.

16 n intraluminal nylon suture coated with poly-L-lysine.

17 w reported for the final member of this set: L-lysine.

18 iety contains a pyridyl residue derived from L-lysine.

19 of bacterial cell walls, and the amino acid L-lysine.

20 cap on a substrate densely coated with poly-L-lysine.

21 converting meso-diaminopimelic acid (DAP) to l-lysine.

22 te; it did not occur in cells plated on poly-l-lysine.

23 specific antigen N-epsilon-2,4-dinitrophenyl-L-lysine.

24 d to adsorb onto a homogeneous layer of poly-l-lysine.

25 , but not by the iNOS inhibitor N-iminoethyl-L-lysine.

26 to be a proton-dependent APC transporter of L-lysine.

27 roteins via acetylation and succinylation of L-lysine.

28 aldimines formed by lyophilization with poly-L-lysine.

29 with CF before and after treatment with poly-L-lysine.

30 eraction was inhibited with neomycin or poly-L-lysine.

31 aspartate aminotransferase (AspAT), and poly-L-lysine.

32 his sequence is involved in the selection of L-lysine.

33 e GTP-dependent phosphorylation of 5-hydroxy-L-lysine.

34 s of meso-diaminopimelic acid (meso-DAP) and L-lysine.

35 of phosphoethanolamine and 5-phosphohydroxy-L-lysine.

36 nsor was proposed for the enantioanalysis of L-lysine.

37 c oxide synthase (iNOS) inhibitor iminoethyl-l-lysine (1), was synthesized and found to be a selectiv

38 5(S)-Fluoro-N6-(iminoethyl)-l-lysine (14), an analogue of the potent, selective indu

39 e, 7beta-[N-Acetyl-L-alanyl-gamma-D-glutamyl-L-lysine]-3-acetoxymethyl-3-ceph em-carboxylic acid (com

40 t site-specific incorporation of delta-thiol-L-lysine (7) and delta-hydroxy-L-lysine (8) into recombi

41 f delta-thiol-L-lysine (7) and delta-hydroxy-L-lysine (8) into recombinant proteins, via evolution of

42 Poly-l-lysine, a PI(4,5)P(2) scavenger, caused rapid desensit

43 f either a specific anti-kringle antibody or L-lysine abolished the interaction.

44 performed by using a modified alginate-poly-l-lysine-alginate encapsulation method to include 10% (w

45 into rat islet microcapsules (alginate-poly[L-lysine]-alginate microcapsule), and 500 suboptimal enc

46 plating on bovine serum albumin-blocked poly-L-lysine (allows attachment, but not integrin ligation a

47 detection of lysine based on the function of L-lysine-alpha-oxidase and lysine-2-monooxygenase are an

48 Based on l-lysine-alpha-oxidase immobilized by co-crosslinking on

49 tyric acid Nalpha',Nalpha-bis(carboxymethyl)-L-lysine amide (NTA-pyrene) and [tris-(2,2'-bipyridine)

50 iformis in complex with the substrate analog L-lysine amide is presented.

51 e proteins, which are rich in l-arginine and l-lysine amino acids, promote COM growth.

52 L-lysine, an inhibitor of L-Arg uptake, attenuated H. py

53 tween the two forms of LysRS, the effects of l-lysine analogues on aminoacylation were investigated.

54 DNA compacted with block copolymers of poly-l-lysine and 10kDa polyethylene glycol (CK(30)PEG(10k)),

55 However, the substrate analogues 4-thia-L-lysine and 4-thia-D-lysine undergo early steps in the

56 xidative deamination of saccharopine to give l-lysine and alpha-ketoglutarate.

57 of polyinosinic-polycytidylic acid with poly-L-lysine and carboxymethyl cellulose (Hiltonol), a poten

58 sinic-polycytidylic acid condensed with poly-l-lysine and carboxymethylcellulose (Poly-ICLC), an agen

59 ysia neurons on geometrical patterns of poly-L-lysine and collagen IV, surrounded by nonadhesive regi

60 s Gram-positive enzyme discriminates between L-lysine and D,L-diaminopimelic acid, the predominant am

61 material, coated with collagen type I, poly-L-lysine and gelatine, was performed by seeding human de

62 utase (LAM) catalyzes the interconversion of l-lysine and l-beta-lysine by a free radical mechanism.

63 LAM), which catalyzes the interconversion of l-lysine and l-beta-lysine.

64 L-Lysine and L-ornithine but not D-Arg produced currents

65 axC transporter was resistant to cadaverine, L-lysine and L-ornithine, which inhibit the E. coli AdiC

66 erentiate in culture dishes coated with poly-l-lysine and mouse laminin in the presence of fibroblast

67 fibrils was evident on mica coated with poly-L-lysine and on glass.

68 The influence of polyions, poly-L-lysine and poly-L-glutamic acid, were investigated to

69 DNA compacted with block copolymers of poly-L-lysine and polyethylene glycol (CK30PEG), which have b

70 The polymeric condensing agents, poly-l-lysine and polyethylenimine, form condensates with nic

71 sphosphate (PIP2)-negative charges with poly-l-lysine and prevented by intracellular dialysis with a

72 LAM) catalyzes the interconversions of D- or L-lysine and the corresponding enantiomers of 2,5-diamin

73 layers consisting of a polyelectrolyte (poly-L-lysine) and an enzyme (tyrosinase).

74 ernative rinses of the cationic polymer poly(l-lysine) and the anionic polymer poly(l-SULA).

75 lypeptide, poly(l-lysine) hydrobromide, poly(l-lysine) and the polymeric dipeptide surfactant, poly(s

76 ls, cationic amino acids such as l-arginine, l-lysine, and l-ornithine are transported by cationic (C

77 -thiaprolyl-L-lysine, N(epsilon)-D-cysteinyl-L-lysine, and N(epsilon)-L-cysteinyl-L-lysine into recom

78 cells were encapsulated with alginate, poly-l-lysine, and perfluorooctyl bromide (PFOB) or perfluoro

79 SAH) bound to the cluster in the presence of l-lysine, and with SAH bound to the cluster in the prese

80 d irreversible suicide inactivation by D- or L-lysine are discussed.

81 ed to stable products, so that 4-thia-D- and L-lysine are suicide inhibitors.

82 Because dendrigraft poly-L-lysines are nonimmunogenic and have low toxicity, this

83 or candidates, and a second polycation, poly-L-lysine, are compared.

84 Growth on L-lysine as a nitrogen source can also be enhanced when

85 d decarboxylation provides an explanation of L-lysine as a poor nutrient for P. aeruginosa.

86 nads, Pseudomonas aeruginosa grows poorly in L-lysine as a sole source of nutrient.

87 ing poly(sodium-4-styrenesulfonate) and poly-l-lysine as negatively and positively charged polyelectr

88 y of Fe3O4@polymer@Au was adopted using poly-l-lysine as the mediate layer, followed by the subsequen

89 antitative installation of N(epsilon)-methyl-L-lysine at defined positions in recombinant histones an

90 he aqueous self-assembly of a series of poly(L-lysine)-b-poly(L-leucine) block copolypeptides, KxLy,

91 An enhanced poly-L-lysine barcode pattern is created on the single-cell b

92 The new one-component systems comprise l-lysine-based dendritic headgroups covalently connected

93 (GABA) and Nalpha,Nalpha-bis(carboxymethyl)-L-lysine (BCML) as competitive inhibitors of quinine-act

94 -directed mutagenesis showed no evidence for L-lysine binding by isothermal titration calorimetry, wh

95 the role of the amino acids responsible for L-lysine binding in the active site of the class II LysR

96 e synthase (HCS) catalyzes the first step of l-lysine biosynthesis in fungi by condensing acetyl-coen

97 of principle, four sets of two genes of the l-lysine biosynthesis pathway distantly located on the E

98 al-5-phosphate-dependent decarboxylase takes L-lysine, but not L-arginine, as a substrate.

99 ls of activated caspase-3 when grown on poly-L-lysine, but not when grown on a laminin-alpha2-contain

100 tained from these studies indicate that poly-L-lysine can induce domains, defects, and aggregate stru

101 arginine metabolism, was found essential for L-lysine catabolism in this organism.

102 uggests a minor role of this transaminase in L-lysine catabolism.

103 hyl)-L-lysine (CML), Nepsilon-(Carboxyethyl)-L-lysine (CEL).

104 ine (CML) and free Nepsilon-(1-Carboxyethyl)-L-Lysine (CEL).

105 onyl fluoride (PMSF) (100%), N-alpha-p-tosyl-l-lysine chloromethyl ketone (TLCK) (85.4%), benzamidine

106 as abrogated by the protease inhibitor tosyl-l-lysine chloromethyl ketone (TLCK) (P < 0.05).

107 protease inhibitors ZnCl2 and Nalpha-p-tosyl-l-lysine chloromethyl ketone (TLCK) exhibited dose-depen

108 (i) was seen with active and Nalpha-p-tosyl-L-lysine chloromethyl ketone (TLCK)-inactivated HRgpA, i

109 ecific inhibitor of trypsin, N-alpha-p-tosyl-L-lysine chloromethyl ketone inhibited 99.67% activity.

110 the protease inhibitors TLCK (Nalpha-p-tosyl-l-lysine chloromethyl ketone) and E-64 [l-trans-epoxysuc

111 e cysteine protease inhibitor Nalpha-p-tosyl-l-lysine chloromethylketone.

112 of free and total Nepsilon-(1-Carboxymethyl)-L-Lysine (CML) and free Nepsilon-(1-Carboxyethyl)-L-Lysi

113 dori products (AP), Nepsilon-(Carboxymethyl)-L-lysine (CML), Nepsilon-(Carboxyethyl)-L-lysine (CEL).

114 A poly-L-lysine coated sensor immobilized with live Escherichia

115 -shaped nanoparticles to the collector (poly-l-lysine coated silica sensor) surface under favorable c

116 We demonstrate this technique using poly(l-lysine)-coated glass surfaces and fibrin gels.

117 cells that exhibit flat lamellipodia on poly-L-lysine-coated coverslips.

118 nsity dissociated cultures are grown on poly-L-lysine-coated glass substrates without feeder layers.

119 lothane and subjected to 2 h of MCAo by poly-l-lysine-coated intraluminal suture.

120 cycline inducer and are adsorbed onto a poly-L-lysine-coated surface, we found that the acrAB-TolC pr

121 e is very similar to positively charged poly-L-lysine-coated surface.

122 Compared with a Poly-L-lysine-coated suture technique, the modified suture te

123 a with mechanical ventilation; Group 5, Poly-L-lysine-coated suture under isoflurane anesthesia; Grou

124 were divided into six groups (Group 1, Poly-L-lysine-coated suture under ketamine/xylazine anesthesi

125 ketamine/xylazine anesthesia; Group 3, Poly-L-lysine-coated suture under ketamine/xylazine anesthesi

126 s-linking with BaCl2 without additional poly-L-lysine coating and were transplanted into abdominal ca

127 Poly-L-lysine compacts CF sputum DNA, generating a liquid pha

128 On the basis of the structure of L-lysine complexed with E. coli LysRS2 (lysS), residues

129 On the basis of the structure of l-lysine complexed with Pyrococcus horikoshii class I Ly

130 were labeled in vitro with ferumoxides-poly-L-lysine complexes.

131 film upon enzymatic degradation of the poly-l-lysine components.

132 lation spectra of the amide I region of poly-l-lysine, concanavalin A, ribonuclease A, and lysozyme s

133 the size of which are a function of the poly-L-lysine concentration, or in other words the size of th

134 this is compensated for by high cytoplasmic L-lysine concentrations.

135 l improvement as compared to the parent octa(l-lysine) conjugate.

136 Design of a poly-l-lysine conjugated polyacrylamide gel allows optimizati

137 ncorporation of N6-[(2-propynyloxy)carbonyl]-L-lysine, containing a carbon-carbon triple bond, and N6

138 riple bond, and N6-[(2-azidoethoxy)carbonyl]-L-lysine, containing an azido group, into recombinant pr

139 d by labeling with Cy5.5 of a pegylated poly-L-lysine copolymer.

140 We first showed that poly-L-lysine could immobilize lentivirus to poly(epsilon-cap

141 Conventional poly-l-lysine-cross-linked microcapsules and unencapsulated i

142 trochemical behavior of nonredox-active poly-L-lysine dendrigraft molecules of four different generat

143 We describe the use of a generation 5 l-lysine dendrimer that has been part-modified with a po

144 carboxylic acid based on a second generation l-lysine dendron interacts with chiral amines and subseq

145 , achieved via deposition of controlled poly(L-lysine) densities, resulted in spatial patterns of tra

146 tion is implicated in the biosynthesis of an L-lysine-derived pyridyl moiety found in streptogramin g

147 A nor react with the epsilon-amino groups of l-lysine, despite the presence of an aziridine ring.

148 of the alpha-Lys* radical: trans-4,5-dehydro-L-lysine (DHLys) and 4-thia-L-lysine (SLys).

149 The addition of N6-(1-iminoethyl)-l-lysine dihydrochloride (L-NIL), the iNOS inhibitor, si

150 Addition of N6-(1-iminoethyl)-L-lysine dihydrochloride, an iNOS inhibitor, significant

151 a iNOS-specific inhibitor, N6-(1-iminoethyl)-L-lysine, dihydrochloride (L-NIL) solely restricts lung

152 0 were tested in mice as protein sigma1-poly-L-lysine-DNA complexes (formulated vaccine) via the intr

153 inic:polycytidylic acid stabilized with poly-l-lysine) during pregnancy produce offspring with abnorm

154 copolymerized with a cationic polymer, poly-L-lysine, effectively immobilizes all sized proteins aft

155 treated with the NOS2 inhibitor N-iminoethyl-L-lysine eliminated parasites as well as control mice.

156 Alginate-poly-L-lysine-encapsulated adult porcine islets were transpla

157 that BacL1 has a peptidoglycan D-isoglutamyl-L-lysine endopeptidase activity via a NlpC/P60 homology

158 ane-active peptides by conjugation onto poly(l-Lysine) enhanced their lytic potential.

159 the switch residues, which interact with the l-lysine epsilon-ammonium group, abrogate feedback inhib

160 anoparticles (Ferumoxides) complexed to poly-L-Lysine (FE-PLL).

161 onformational changes of a polypeptide (poly-l-lysine) film upon temperature-induced changes of the h

162 dopeptidase cathepsin B, connected to oligo-(L)-lysine for nucleic acid binding, (ii) pHCath(D)K(10),

163 N6-(glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)] catalyzes the final step in the alpha

164 ee structures of saccharopine dehydrogenase (l-lysine-forming) (SDH) have been determined in the pres

165 om internal free polyelectrolyte; here, poly-l-lysine forms the network and inflates the capsules.

166 We detected the proteolytic release of free L-lysine from peptide digests using a rapid, simple, sen

167 , CML, CEL and the Nepsilon-(2-Furoylmethyl)-L-lysine (furosine), the indirect marker of AP.

168 Using L-lysine gamma-substituted peptide nucleic acids, the mu

169 ase activity and N(Sigma)-(gamma-L-glutamyl)-L-lysine (GGEL) levels were significantly altered in HD

170 mer brush and further functionalized by poly-l-lysine graft PEG (PLL-PEG) copolymers.

171 metry (TOF-SIMS) to investigate several poly(L-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG) adlaye

172 opriately structured and functionalized poly(l-lysine)-graft-poly(ethylene glycol) (PLL-g-PEG) copoly

173 T47D cells seeded on poly-L-lysine had an abrogated mitogenic response, indicating

174 As crystalline L-lysine has a strong propensity to incorporate water un

175 he midpoint reduction potential upon binding l-lysine has been estimated to be -0.6 V from the values

176 ers of hydrophilic, charged segments of poly(l-lysine HBr) or poly(l-glutamic acid sodium salt), and

177 rther modified with N,N'-bis (carboxymethyl)-l-lysine hydrate to bind copper ions and then, chelate h

178 coating consisting of the polypeptide, poly(l-lysine) hydrobromide, poly(l-lysine) and the polymeric

179 er, methoxy-poly(ethylene glycol)-block-poly(L-lysine hydrochloride) (PEG-pLL(5)(0)).

180 , we show that silicas synthesized with poly-L-lysine in a alpha-helix conformation possess cylindric

181 size, whereas silicas synthesized with poly-L-lysine in a beta-sheet conformation possess larger por

182 embrane by electrostatic association of poly-l-lysine in an attempt to elucidate the complex factors

183 id, the predominant amino acid that replaces L-lysine in Gram-negative peptidoglycan.

184 nsor can be applied for the determination of L-lysine in serum samples and pharmaceutical compounds.

185 on with fibronectin (Fn) or adhesion by poly-L-Lysine in serum-starved precursor B leukemia cells.

186 ndent amide I'-II' 2D IR experiments on poly-l-lysine in the beta-sheet, alpha-helix, and random coil

187 s induced by exogenous L-arginine but not by L-lysine in the wild-type strain PAO1, and the binding o

188 -tryptophan) and a polypeptide (epsilon-poly-l-lysine) in prolonging the color stability of purple ca

189 photoresist together with patterning of poly(l-lysine) in register with electrodes to promote cell ad

190 nic peptides melittin, polymyxin B, and poly-l-lysine, in a manner that paralleled that of Brucella a

191 Poly-L-lysine-induced morphological changes in liquid phase s

192 Blockade of l-arginine uptake by l-lysine inhibited NOS activity and, conversely, blockad

193 that were identified in a previous study of l-lysine-insensitive HCS mutants in Saccharomyces cerevi

194 steinyl-L-lysine, and N(epsilon)-L-cysteinyl-L-lysine into recombinant proteins in Escherichia coli .

195 Poly-L-lysine is used as a model polypeptide as its folding b

196 Poly-L-lysine is used to promote the binding of Fld to the na

197 ease in selectivity and resolution when poly(l-lysine) is used as the cationic polymer in place of PD

198 hesize that AGPHD1 corresponded to 5-hydroxy-L-lysine kinase and that AGXT2L1 and AGXT2L2 catalyzed t

199 acids--L-phenylalanine, L-leucine, glycine, L-lysine, L-arginine, L-cysteine, L-alanine, and L-proli

200 .03-24% L-threonine, D-threonine, L-leucine, L-lysine, L-glutamic acid, or diglycine with L-serine as

201 in complex with the amino acids L-arginine, L-lysine, L-phenylalanine, L-tryptophan, and L-tyrosine.

202 In BMMCs stimulated by poly-L-lysine, lamellopodia and filopodia were observed in as

203 nd different generations of dendrigraft poly-L-lysines leading to quantitative information (i.e., sto

204 olecules of aldehyde 29 with one molecule of l-lysine led by analogous chemistry to the first synthes

205 vothermal route assisted amino acids such as L-Lysine (lysine), L-Cysteine (cysteine) and L-Arginine

206 sequently encapsulated or embedded in a poly-L-lysine matrix, it is concluded that the encapsulation

207 Poly-L-lysine may be an alternative to dornase-alpha to lique

208 The metabolomic analysis indicated that l-lysine, mellein, and gallic acid were significantly mo

209 g cells within a semipermeable alginate-poly-L-lysine membrane as a means of delivery to tumor sites

210 dispersed and encapsulated in alginate-poly-l-lysine microcapsules wherein the cells spontaneously c

211 as fabricated by loading catalase (CAT) onto l-lysine/multiwalled carbon nanotube (PLL/f-MWCNT) film

212 fic incorporation of N(epsilon)-L-thiaprolyl-L-lysine, N(epsilon)-D-cysteinyl-L-lysine, and N(epsilon

213 Saccharopine dehydrogenase [N6-(glutaryl-2)-L-lysine:NAD oxidoreductase (L-lysine forming)] catalyze

214 e (NAC), N-acetylcysteamine, and N(2)-acetyl-L-lysine (NAL) have been studied, and the thiol addition

215 reaction (furosine, Nepsilon-(carboxymethyl)-l-lysine, Nepsilon-(carboxyethyl)-l-lysine, total lysine

216 alpha-secretase substrate, benzyloxycarbonyl-l-lysine o-nitrophenyl ester (Z-lys-o-Np) as a prelimina

217 We propose that poly-L-lysine of sufficient length interacts with the mica su

218 om Ala-tRNAAla to the epsilon-amino group of l-lysine of UDP-MurNAc pentapeptide.

219 ncluding the molar mass distribution of poly-L-lysine oligomers by capillary gel electrophoresis (CGE

220 e antibacterial activity of dendrigraft poly-L-lysines on Micrococcus luteus and Erwinia carotovora.

221 crofibrils adsorbed to mica coated with poly-L-lysine or to borosilicate glass substrates had a more

222 in ceramide and apoptosis in HBMECs on poly-l-lysine or vitronectin, although cells detached only fr

223 ctroscopy in reactions of 5,6-LAM with D- or L-lysine or with L-beta-lysine.

224 observed in surfaces coated with either poly(L-lysine) or anti-CD3 mAb.

225 ass slides coated with aldehyde silane, poly-l-lysine, or aminosilane (with or without activation wit

226 he biosensor is based on the impregnation of L-lysine oxidase in diamond paste.

227 block copolymer poly(ethylene glycol)-b-poly(L-lysine) (PEG-PLL) followed by chemical cross-linking.

228 ontext, it was discovered that a simple octa(l-lysine) peptide covalently linked to the PNA is capabl

229 zation of the particles was achieved by poly(L-lysine) (PL) encapsulation.

230 gold) modified with a polymeric film of poly-L-lysine (PLL) and chitosan.

231 to examine the solution conformation of poly-l-lysine (PLL) and poly-l-glutamic acid (PGA) in their n

232 ted from poly-l-glutamic acid (PGA) and poly-l-lysine (PLL) can be loaded, post-fabrication, by infus

233 d release were monitored on silica- and poly-l-lysine (PLL) coated surfaces as a function of GO conce

234 ious concentrations of ferumoxides (FE)-poly-l-lysine (PLL) complexes were used to magnetically label

235 ith multimodal imaging reporter labeled poly-L-lysine (PLL) demonstrated high therapeutic efficacy in

236 ylated carbon nanotubes (COOH-CNTs) and poly-L-lysine (PLL) film was developed and applied to serum s

237 Heparin was covalently immobilized on poly-l-lysine (PLL) layer with multiple binding sites by sulf

238 roperties of DNA condensed using 19-mer poly-L-lysine (PLL) or branched histidine-lysine (HK) peptide

239 Poly-L-lysine (PLL) promotes the precipitation of silica from

240 iously unreported intrinsic capacity of poly-L-lysine (PLL) sixth generation (G(6)) dendrimer molecul

241 Here, we use a poly-L-Lysine (PLL) surface that captures all protein compone

242 scorbic acid, gold chroloauric acid and poly-l-lysine (PLL) through modified layer-by-layer (LbL) met

243 Four surface modification chemistries, poly-L-lysine (PLL), 3-glycidoxypropyltrimethoxysilane (GPS),

244 The polymer poly-L-lysine (PLL), a probe concentration of 1 muM and an im

245 ocompatible 40 kDa esteramide (EA)- and poly-l-lysine (PLL)-based dendrimers capable of binding up to

246 c cell-based biosensor constructed from poly-l-lysine (PLL)-modified screen-printed carbon electrode

247 omenon that involves positively charged poly(L-lysine) (PLL) and negatively charged gold nanoparticle

248 The 300-kDa poly(L-lysine) (PLL) or poly(D-lysine) (PDL) was labeled with

249 on other surfaces, we hypothesized that poly(L-lysine) (PLL), an analog of the protein catalyst respo

250 While the positively charged poly-L-lysine, PLL, did not show any significant effect, nega

251 analogue N-epsilon-[(cylopentyloxy)carbonyl]-L-lysine plus ATP.

252 ytidylic acid [poly IC] stabilized with poly-L-lysine [poly ICLC]), an agonist for toll-like receptor

253 beta-sheet conformational transition of poly(L-lysine) [poly(K)].

254 ore sensitive to the cationic peptides, poly-l-lysine, polymyxin-B, and melittin.

255 stimulated, and inhibited by alpha-trimethyl-L-lysine, properties assigned to lysosomal transport sys

256 The structure of the transient 4-thia-L-lysine radical is analogous to that of the first subst

257 les were formed using polyallylamine or poly-L-lysine ranging from 0.2 to 5 microm in diameter.

258 hed rather than linear lysine oligomer, with l-lysine replaced by d-lysine, and with lysine replaced

259 taining an permittivity-(2-(aminooxy)acetyl)-L-lysine residue.

260 esses by catalyzing the hydrolysis of acetyl-l-lysine residues in histone and nonhistone proteins.

261 esized materials is consistent with the poly-L-lysine retaining its secondary structure.

262 CO)(3) chelator N-omega-bis(2-pyridylmethyl)-L-lysine (RGD4C-DPK) and were significantly higher (P <

263 lycation end product, Nepsilon-carboxymethyl-L-lysine, ruling out effects of cellular advanced glycat

264 Despite the absolute specificity for L-lysine, S. aureus MurE binds this substrate relatively

265 of the synthesis mixtures show that the poly-L-lysine secondary structure is not perturbed during syn

266 ntrast, the force-extension behavior of poly(L-lysine) showed no deviation in the relevant force rang

267 rans-4,5-dehydro-L-lysine (DHLys) and 4-thia-L-lysine (SLys).

268 lecular umbrellas, derived from cholic acid, L-lysine, spermidine, and Cascade Blue, to cross fluid l

269 ndicate that it functions in vitro as a poly-L-lysine-stimulated kinase that is capable of autophosph

270 endogenous kinase activities, including poly-L-lysine-stimulated kinases that target various constitu

271 ds; however, no growth of the ldcA mutant on L-lysine suggests a minor role of this transaminase in L

272 inistered to oligodendrocytes plated on poly-L-lysine, supporting a role for Gas6 signaling in oligod

273 g of the cell onto a dense, homogeneous poly-L-lysine surface appears complete in <1 s with occasiona

274 thetase (SyrE), N(epsilon)-(indole-3-acetyl)-l-lysine synthetase (IaaL), and a subsidiary regulon con

275 PGN of S. aureus with l-lysine tethered with d-alanine via a pentaglycine brid

276 For poly-l-lysine, the 2D IR spectrum contains the eight-peak str

277 nlarging the substrate binding pocket allows L-lysine to be accommodated.

278 transferase-catalyzed reaction that converts L-lysine to Delta(1)- or Delta(2)-piperideine-2-carboxyl

279 of RapL and validate its ability to convert L-lysine to L-pipecolic acid by a cyclodeamination react

280 Thus, the binding of l-lysine to LAM contributes 4 kcal mol-1, and the bindin

281 Binding of L-lysine to STM2200 in its solubilized monomer form is e

282 oxymethyl)-l-lysine, Nepsilon-(carboxyethyl)-l-lysine, total lysine).

283 Poly-L-lysine toxicity was evaluated after aerosolization by

284 lyethylene glycol linked to a 30-mer of poly-l-lysine via a single cysteine residue (CK(30)PEG) have

285 The potential used for the determination of l-lysine was 650 mV.

286 The N-methyl phosphonate derivative of l-lysine was a potent competitive inhibitor of Cc2672 wi

287 of 8.5, cooperative substrate activation by L-lysine was depicted from kinetics studies, with calcul

288 Rapid growth on L-lysine was detected in a mutant devoid of the main arg

289 layer (PEM) approach using alginate and poly-l-lysine was employed to coat cell spheroids.

290 which incorporation of radioactively labeled L-lysine was enhanced in cells grown in the presence of

291 When L-lysine was used as the substrate, MS analysis suggeste

292 inic:polycytidylic acid stabilized with poly-L-lysine) was delivered to two separate groups of pregna

293 umin (DNP-BSA) and secretagogues (e.g., poly-L-lysine) was investigated by combined atomic force micr

294 Antibacterial properties of poly-L-lysine were measured in bacterial cultures and in whol

295 of the reaction is the essential amino acid l-lysine, which is an important precursor for the synthe

296 the chiral induction effect of a C-terminal l-lysine, which is transmitted through stacking interact

297 0-fold higher than for either l-ornithine or l-lysine, which were decarboxylated with similar efficie

298 nd-binding domain of the riboswitch binds to L-lysine with an apparent dissociation constant (KD) of

299 und to the cluster and l-alanine in place of l-lysine, with S-adenosyl-l-homocysteine (SAH) bound to

300 We examined whether poly-L-lysine would compact DNA in CF lung secretions and liq