ライフサイエンスコーパス: L-phenylalanine

1 -amide ([Bpa23]PTHrP, where Bpa is p-benzoyl-L-phenylalanine).

2 inity to Phe-Sepharose and elution with free l-phenylalanine.

3 n the potentiation of the activity of CaR by l-phenylalanine.

4 tly discriminated with a minor conversion of l-phenylalanine.

5 neously produced both BH4 and 3, 4-dihydroxy-L-phenylalanine.

6 fructose- or glucose-based minimal medium by L-phenylalanine.

7 the reactive noncanonical amino acid p-azido-L-phenylalanine.

8 omography and 3,4-dihydroxy-6-[(18)F]-fluoro-l-phenylalanine.

9 ross-linkable unnatural amino acid p-benzoyl-L-phenylalanine.

10 amygdalin, which are presumably derived from L-phenylalanine.

11 eric dipeptide derivatives formed from N-Boc-L-phenylalanine.

12 ing the novel fluorescent species 4-biphenyl-l-phenylalanine (1), have been incorporated at positions

13 d increases in 3,4-dihydroxy-6-[(18)F]fluoro-L-phenylalanine ((18)F-DOPA) uptake in the striatum of s

14 ne ((18)F-FET), 3,4-dihydroxy-6-(18)F-fluoro-l-phenylalanine ((18)F-DOPA), and (11)C-methionine ((11)

15 tic approach to 6-(18)F-fluoro-3,4-dihydroxy-L-phenylalanine ((18)F-DOPA), involving the nucleophilic

16 using PET with 3,4-dihydroxy-6-(18)F-fluoro-l-phenylalanine ((18)F-FDOPA) and (18)F-FDG.

17 the accuracy of 6-(18)F-fluoro-3,4-dihydroxy-l-phenylalanine ((18)F-FDOPA) PET for insulinoma diagnos

18 omography and 3,4-dihydroxy-6-[(18)F]-fluoro-l-phenylalanine ([(18)F]-DOPA).

19 ysozyme and bovine serum albumin (BSA) by N-(l-phenylalanine)-4-(1-pyrene)butyramide (Py-Phe) is repo

20 ine (2), L-isoleucine (3), L-tryptophan (4), L-phenylalanine (5), L-arginine (6) has been accomplishe

21 no-bicyclo[2,2.1]-heptane-2-carboxylic acid, L-phenylalanine, 6-diazo-5-oxo-norleucine, L-glutamine,

22 ed photoreactive derivative of SP, p-benzoyl-L-phenylalanine(8)-substance P (125I-[Bpa8]SP).

23 ration of the unnatural amino acid p-benzoyl-L-phenylalanine, a photoreactive cross-linker, we mapped

24 orporated the unnatural amino acids p-acetyl-L-phenylalanine (Acp) and p-benzoyl-L-phenylalanine (Bzp

25 f sarcolysin [(L-3-[bis(2-chloroethyl)amino]-L-phenylalanine] against all leukemias and lymphomas, ID

26 ting the amino acid analogue trifluoromethyl-L-phenylalanine allows larger proteins (up to 100 kDa) t

27 nylalanine methyl ester and beta-CD/N-acetyl-L-phenylalanine amide.

28 lanine methyl ester/beta-CD and 2:2 N-acetyl-L-phenylalanine amide/beta-CD complexes were reported.

29 xy-3-methylglutaryl CoA reductase (HMGR) and l-phenylalanine ammonia lyase (PAL), two defense genes e

30 L-Phenylalanine ammonia-lyase (PAL) is the first enzyme

31 g development and adaptation, and depends on L-phenylalanine ammonia-lyase (PAL), an enzyme catalyzin

32 Genes encoding L-phenylalanine ammonia-lyase (PAL), chalcone synthase (

33 first enzyme in the phenylpropanoid pathway, L-phenylalanine ammonia-lyase (PAL).

34 The downregulation of l-phenylalanine ammonia-lyase, 4-coumarate 3-hydroxylase

35 ous (bean) phenylalanine ammonia-lyase (PAL; L-phenylalanine ammonia-lyase, EC 4.3.1.5) gene, modifie

36 a similar diet containing 0.5% AMPhe + 3.0% L-phenylalanine (AMPhe + Phe diet) from day 11 until day

37 10 mm l-phenylalanine and 1 microm NPS R-467, submaximal doses

38 two 8-substituted benzolactams starting from L-phenylalanine and characterize their isozyme selectivi

39 recombinant enzyme in the complexes, E.NADH.L-phenylalanine and E.NAD(+).

40 strong allosteric behavior in the binding of l-phenylalanine and l-alanine but not in that of bicarbo

41 However, L-phenylalanine and L-arginine are also good germinants

42 epresentative 30-mer CMP, (GPO)(10), as with l-phenylalanine and l-pentafluorophenylalanine in 32-mer

43 ely 65%) with plant L-tyrosine/3,4-dihydroxy-L-phenylalanine and L-tryptophan decarboxylases.

44 , especially aromatic amino acids, including l-phenylalanine and l-tryptophan, stereoselectively mobi

45 nts suggest that the pathways to lignin from L-phenylalanine and L-tyrosine are distinct beyond the f

46 L-phenylalanine and L-tyrosine are the only two natural

47 Two of these were identified as L-phenylalanine and L-tyrosine but it may be that metabo

48 (189)Ala-Ser-Gly(191) residues and the bound l-phenylalanine and l-tyrosine, conferring the deaminati

49 with some receptors being more responsive to l-phenylalanine and others being more responsive to NPS

50 ld increased protein production for p-acetyl-L-phenylalanine and p-azido-L-phenylalanine (pAzF).

51 was examined through uptake of L-leucine and L-phenylalanine and provided Km and Vmax values of appro

52 Recombinant EncP is specific for L-phenylalanine and shares many biochemical features wit

53 oducts resulting from transamination between L-phenylalanine and the alpha-ketoglutarate analogues we

54 Transamination between L-glutamate (or L-phenylalanine) and the alpha-ketoglutarate analogues w

55 Aminoacylation [BOC-(4-methoxy-L-phenylalanine)] and deprotection gave puromycin and 7-

56 enylalanine, p-iodo-L-phenylalanine, p-bromo-L-phenylalanine, and L-3-(2-naphthyl)alanine.

57 aromatic amino acids, including l-tyrosine, l-phenylalanine, and l-tryptophan, in the reaction did n

58 cine (Fru-D-Leu), N-(1-deoxy-D-fructos-1-yl)-L-phenylalanine, and N-(1-deoxy-D-fructos-1-yl)-L-leucin

59 etyl-L-methionine, N-acetylglycine, N-acetyl-L-phenylalanine, and N-acetyl-L-alanine at 298.35K by po

60 ttle as 1% enantiomeric excess (ee) of D- or L-phenylalanine are amplified to 90% ee (a 95/5 ratio) b

61 r competitive inhibition by L-tryptophan and L-phenylalanine are similar for wild-type, R381A, and R3

62 Aromatic amino acids (i.e., L-trytophan and L-phenylalanine) are also retained on MProP columns thro

63 o acids, such as glycyl-l-alanine and glycyl-l-phenylalanine, are also good acceptors.

64 The most effective analogues utilized an L-phenylalanine as the amino acid component.

65 for complexes of beta-cyclodextrin/N-acetyl-L-phenylalanine at 298 and 20 K and for N-acetyl-D-pheny

66 in the photoactivatable amino acid p-benzoyl-L-phenylalanine at positions 6 or 9 cross-link to phosph

67 The polar groups of L-phenylalanine at the surface transition to their depro

68 ltraviolet-induced crosslinking with p-azido-L-phenylalanine (azF) at selected positions in hSERT to

69 lly encoded the unnatural amino acid p-azido-L-phenylalanine (azF) at various specific sites in a G p

70 corporate the photoactive amino acid p-azido-l-phenylalanine (azF) into N-terminal residues of a full

71 The photo-cross-linker p-azido-L-phenylalanine (AzF) was encoded in NMDA receptors (NMD

72 Glycyl-L-phenylalanine-beta-naphthylamide (GPN) was used to rel

73 ining the photoreactive amino acid p-benzoyl-l-phenylalanine (Bpa) in position 8 of the C-terminal po

74 ctive derivatives of SP containing p-benzoyl-L-phenylalanine (Bpa) in positions 4 and 8, respectively

75 ecifically evolved to incorporate p-benzoyl- l-phenylalanine (Bpa) in response to the amber codon all

76 or that incorporates a photolabile p-benzoyl-L-phenylalanine (Bpa) into the position of Leu22 and hav

77 in that incorporated a photolabile p-benzoyl-l-phenylalanine (Bpa) residue into its pharmacophoric do

78 7) that incorporates a photolabile p-benzoyl-L-phenylalanine (Bpa) residue into position 6 of the ami

79 al approximations with photolabile p-benzoyl-l-phenylalanine (Bpa) residues sited at each end of CCK

80 equence diethylglycine (Deg)(1)-para-benzoyl-l-phenylalanine (Bpa)(2)-Deg(3).

81 ing the photo-cross-linkable group 4-benzoyl-L-phenylalanine (Bpa).

82 ining the photoreactive amino acid p-benzoyl-L-phenylalanine (Bpa).

83 ential to observe the potentiating action of l-phenylalanine but not of NPS R-467 on the receptor.

84 tely in the presence of either L-tyrosine or L-phenylalanine, but PhhB exhibits a significant basal l

85 glycine, N-acetyl-L-methionine, and N-acetyl-L-phenylalanine by porcine acylase I in 0.1M phosphate b

86 photoreactive unnatural amino acid p-benzoyl-l-phenylalanine (BzF) at 11 selected individual position

87 f unnatural amino acids, including p-benzoyl-l-phenylalanine (BzF, also known as Bpa), had largely si

88 p-acetyl-L-phenylalanine (Acp) and p-benzoyl-L-phenylalanine (Bzp) into CCR5 at high efficiency in ma

89 taining m-acetyl-l-phenylalanine or p-acetyl-l-phenylalanine can be selectively labeled with hydrazid

90 olysis using the protease inhibitors N-tosyl-L -phenylalanine chloromethyl ketone and N-acetyl-L -leu

91 r (75.6%) and partially inhibited by N-tosyl-l-phenylalanine chloromethyl ketone (TPCK) (10.3%), ethy

92 er that the serine protease inhibitors tosyl-L-phenylalanine chloromethyl ketone (TPCK) and tosyl-L-l

93 The serine protease inhibitor N-tosyl-L-phenylalanine chloromethyl ketone (TPCK) effectively b

94 tion by the protease inhibitor N-alpha-tosyl-L-phenylalanine chloromethyl ketone (TPCK) prevents UV a

95 Treatment of WEH1 231 cells with N-tosyl-L-phenylalanine chloromethyl ketone (TPCK), a protease i

96 ogenase isozymes were inactivated by N-tosyl-L-phenylalanine chloromethyl ketone (TPCK), an inhibitor

97 l inhibitors of NF-kappa B, SN50 and N-tosyl-l-phenylalanine chloromethyl ketone (TPCK), blocks TNF-i

98 serine/threonine protease inhibitor N-tosyl-L-phenylalanine chloromethyl ketone (TPCK), which blocks

99 inhibited by the protease inhibitor N-Tosyl-L-Phenylalanine Chloromethyl Ketone (TPCK).

100 -fmk) or the serine protease inhibitor tosyl-L-phenylalanine chloromethyl ketone (TPCK).

101 ological inhibitors of this pathway, N-tosyl-l-phenylalanine chloromethyl ketone and pyrrolidine dith

102 ersed by NF-kappaB inhibitors, e.g., N-tosyl-l-phenylalanine chloromethyl ketone and SN50, a result t

103 acystin beta-lactone, ALLN, and Nalpha-tosyl-L-phenylalanine chloromethyl ketone and was relatively u

104 rbamate and the proteasome inhibitor N-tosyl-L-phenylalanine chloromethyl ketone blocked expression o

105 ed by using a NF-kappaB inhibitor (N-p-Tosyl-L-phenylalanine chloromethyl ketone) that restored PGC-1

106 s inhibitor, and more specifically N-p-tosyl-L-phenylalanine chloromethyl ketone, a chymotrypsin-like

107 ctivation, which could be blocked by N-tosyl-L-phenylalanine chloromethyl ketone, calpeptin, and pyrr

108 ng 3,4-dichloroisocoumarin, N(alpha)-p-tosyl-L-phenylalanine chloromethyl ketone, N(alpha)-p-tosyl-L-

109 he serine protease inhibitor N alpha-L-tosyl-L-phenylalanine chloromethyl ketone, suggesting that a n

110 enzenesulfonyl fluoride and N(alpha)-p-tosyl-L-phenylalanine chloromethyl ketone.

111 protease inhibitor, CrmA, and N-alpha-tosyl-L-phenylalanine chloromethyl ketone.

112 The crystal structures for the N-acetyl-L-phenylalanine complex present disordered inclusion com

113 luoride, p-hydroxymercuribenzoate, and tosyl-l-phenylalanine, consistent with the proposed presence o

114 he most promising compounds were (4-amidino)-L-phenylalanine-containing inhibitors, which reached nan

115 thy donor with N-formyl-L-methionyl-L-leucyl-L-phenylalanine could also cause them to sediment aberra

116 e" to the resolution of the mechanism of the l-phenylalanine dehydrogenase catalyzed reaction.

117 The molecular structures of recombinant L-phenylalanine dehydrogenase from Rhodococcus sp. M4 in

118 Both structures show that L-phenylalanine dehydrogenase is a homodimeric enzyme wi

119 mate dehydrogenase, L-leucine dehydrogenase, L-phenylalanine dehydrogenase, lactate dehydrogenase, ma

120 harging tRNA in trans with various activated l-phenylalanine derivatives.

121 by a one-pot Knoevenagel-IMDA reaction of an l-phenylalanine-derived tetramic acid and (R)-2-methyl-d

122 henylalanyl-L-leucyl-L-phenylalanyl-L-leucyl-L- phenylalanine did not inhibit basal GTPgammaS binding

123 of (3)H-trans-cinnamic acid formed from (3)H-l-phenylalanine did not equilibrate with exogenous trans

124 ence of the unusual amino acid 3,4-dihydroxy-L-phenylalanine (dopa), which is formed by posttranslati

125 discriminate between enantiomers of dansyl-D,L-phenylalanine (DPs) by changing the local environment

126 at the S1 specificity site, while that of D,L-phenylalanine enantiomorphs is compared in the S3 regi

127 l-Valine, l-isoleucine, and l-phenylalanine esters of [3-(hydroxymethyl)phenyl]guani

128 new fluorescent chiral ionic liquid (FCIL), l-phenylalanine ethyl ester bis(trifluoromethane) sulfon

129 ed FCIL, derived from commercially available l-phenylalanine ethyl ester chloride and lithium bis(tri

130 intermediates: 4-[bis(2-chloroethyl)-amino]-L-phenylalanine ethyl ester trifluoroacetate (6) and 1-(

131 and absence of N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP) (1 muM) stimulation.

132 reconstituted N-formyl-L-methionyl-L-leucyl-L-phenylalanine (FMLP)-stimulated guanosine 5'-O-(3-thio

133 he effects of (N-formyl-L-methionyl-L-leucyl-L-phenylalanine (fMLP)-stimulation on its mechanical pro

134 luding lowering the pK(a) of nonacidic C3 of l-phenylalanine for an E1cb mechanism) is potentially go

135 corporated the unnatural amino acid p-acetyl-L-phenylalanine for specific labeling of the protein wit

136 pharmacokinetics of 4-borono-2-(18)F-fluoro-L-phenylalanine-fructose ((18)F-FBPA-Fr) in F98 glioma-b

137 , [l-Phe-Gly + M + H](+) (where l-Phe-Gly is l-phenylalanine-glycine), and [Mn(II) + (l-Phe-Gly - H)

138 In contrast, l-phenylalanine has little effect on the Hill coefficien

139 L-phenylalanine has the unique advantage of possessing t

140 of l-amino acid oxidase with its substrate (L-phenylalanine) has been refined to a resolution of 1.8

141 were insignificant, suggesting a pooling of L-phenylalanine in HDPC.

142 e hydroxylase, DL-p-chlorophenylalanine, and L-phenylalanine in the diet.

143 identify changes in the ionization state of L-phenylalanine in the surface region versus the bulk aq

144 Feeding white campion flowers with [(13)C9]l-phenylalanine increased guaiacol and veratrole emissio

145 of protein variant H163A in the presence of l-phenylalanine indicated a functional role of His(163)

146 inhibitors of N-formyl-l-methionyl-l-leucyl-l-phenylalanine-induced migration of human neutrophils,

147 ylase (PheOH) catalyzes the hydroxylation of l-phenylalanine into l-tyrosine utilizing the cofactors

148 ytochrome P450s catalyzing the conversion of L-phenylalanine into mandelonitrile via phenylacetaldoxi

149 ut not CYP79A68, catalyzed the conversion of L-phenylalanine into phenylacetaldoxime.

150 photolabile probes incorporating a p-benzoyl-l-phenylalanine into positions 16 and 20 of GLP1(7-36).

151 tively and efficiently incorporates m-acetyl-l-phenylalanine into proteins in E. coli.

152 sible the in vivo incorporation of p-benzoyl-l-phenylalanine into proteins in Escherichia coli in res

153 t probe incorporated a photolabile p-benzoyl-l-phenylalanine into the position of His(1) of rat secre

154 which are responsible for the conversion of L-phenylalanine into trans-cinnamic acid in eukaryotic a

155 Incorporation of p-azido-l-phenylalanine into two predetermined positions of Uox

156 incorporation of a keto amino acid, p-acetyl-l-phenylalanine, into proteins in E. coli with high tran

157 oreactive, non-natural amino acid, p-benzoyl-l-phenylalanine, into various positions of the structura

158 In addition to proteins, L-phenylalanine is a versatile precursor for thousands o

159 N-(4-Methoxyphenylazoformyl)-L-phenylalanine is efficiently cleaved by the enzyme bov

160 3H-l-Phenylalanine is incorporated into a range of phenylpr

161 e DA-deficient (DA-/-) mice to 3, 4-dihyroxy-L-phenylalanine (L-DOPA) to investigate the relationship

162 stering the dopamine precursor 3,4-dihydroxy-l-phenylalanine (l-DOPA) to pregnant mice in drinking wa

163 In cells incubated with 3,4-dihydroxy-L-phenylalanine (L-DOPA), catecholamines increased by ap

164 ate a redox-active amino acid, 3,4-dihydroxy-l-phenylalanine (l-DOPA), that selectively forms a coval

165 ice through administration of 3, 4-dihydroxy-l-phenylalanine (l-Dopa), thereby permitting the assessm

166 1 and 2 has been implicated in 3,4-dihydroxy-l-phenylalanine (L-DOPA)-induced dyskinesia (LID), a mot

167 repinephrine, epinephrine, and 3,4-dihydroxy-l-phenylalanine (L-DOPA).

168 Amino acids L-tryptophan (L-Trp) and L-phenylalanine (L-Phe) activated GPR139, with EC50 valu

169 eATE) is a three-domain subunit, recognizing L-phenylalanine (L-Phe) and activating it (by adenylatio

170 tion (<2min) and accurate quantifications of L-phenylalanine (L-Phe) in plasma and whole-blood newbor

171 To understand the effect of l-phenylalanine (l-phe) on the PAL activity, total pheno

172 zes the hydroxylation of aromatic amino acid l-phenylalanine (L-Phe) to l-tyrosine (L-Tyr).

173 activation, thiolation and epimerization of L-phenylalanine (L-Phe), the first amino acid incorporat

174 cellular [Ca(2+)] or by aromatic amino acid, L-phenylalanine (L-Phe, endogenous component of saliva),

175 that barbamide is synthesized from acetate, L-phenylalanine, L-cysteine and L-leucine with trichloro

176 s indicated that it is derived from acetate, L-phenylalanine, L-leucine and L-cysteine.

177 l structure of eight individual amino acids--L-phenylalanine, L-leucine, glycine, L-lysine, L-arginin

178 x with the amino acids L-arginine, L-lysine, L-phenylalanine, L-tryptophan, and L-tyrosine.

179 The potential of three amino acids (l-phenylalanine, l-tyrosine, l-tryptophan) and a polypep

180 formed by TATase-catalyzed transamination of l-phenylalanine, l-tyrosine, l-tryptophan, l-methionine,

181 (6BH(4)) is crucial in the hydroxylation of L-phenylalanine-, L-tyrosine-, and L-tryptophan-regulati

182 at enhances dopaminergic function (dihydroxy-L-phenylalanine; L-DOPA) during the imaginative construc

183 at enhances dopaminergic function (dihydroxy-L-phenylalanine; L-DOPA) increases an optimism bias.

184 nistration of drugs enhancing (3,4-dihydroxy-L-phenylalanine; L-DOPA) or reducing (haloperidol) dopam

185 phenylalanine derivatives: beta-CD/N-acetyl-L-phenylalanine methyl ester and beta-CD/N-acetyl-L-phen

186 In fact, 1-boraadamantane.l-phenylalanine methyl ester complex (5), 1-boraadamanta

187 allographic studies of both the 2:2 N-acetyl-L-phenylalanine methyl ester/beta-CD and 2:2 N-acetyl-L-

188 determination for the 2:2 N-acetyl-p-methoxy-L-phenylalanine methyl ester/beta-CD inclusion complex.

189 ructures of complexes of the model, N-acetyl-L-phenylalanine methylamide, bound to the alpha and beta

190 umor as a consequence of low-dose melphalan (l -phenylalanine mustard (l -PAM)) treatment (l -PAM TuB

191 dministration of low-dose melphalan (l -PAM, l -phenylalanine mustard) to mice bearing a large MOPC-3

192 trating lymphocytes from low-dose melphalan (L-phenylalanine mustard (L-PAM))-treated MOPC-315 tumor

193 Sensitivities of L-phenylalanine mustard-resistant and methotrexate-resis

194 ve previously shown that low dose melphalan (L-phenylalanine mustard; L-PAM) therapy of hitherto immu

195 t administration of a low-dose of melphalan (L-phenylalanine mustard; L-PAM) to mice bearing a large

196 ), spermine (Spm), epibrassinolide (EBL) and l-phenylalanine on sweet basil (Ocimum basilicum L.) wer

197 is stimulated by NBAT expression, but unlike L-phenylalanine or L-arginine transport, L-histidine tra

198 ruginosa abolished ability to utilize either L-phenylalanine or L-tyrosine as a sole source of carbon

199 hibiting no detectable activity toward 2-aza-L-phenylalanine or L-tyrosine as an alternative substrat

200 Catalysts 1-4 were prepared starting from l-phenylalanine or l-tyrosine methyl esters and supporti

201 emonstrate that proteins containing m-acetyl-l-phenylalanine or p-acetyl-l-phenylalanine can be selec

202 olayers of l-cysteine-l-tyrosine, l-cysteine-l-phenylalanine, or l-cysteine-l-phosphotyrosine formed

203 rate selectivity and kinetic activity toward L-phenylalanine over L-tyrosine.

204 IL-4-induced gene-1 (IL4I1), a secreted l-phenylalanine oxidase expressed by APCs, has been dete

205 ically encoded unnatural amino acid p-acetyl-L-phenylalanine (p-AcPhe) is reacted with a hydroxylamin

206 ylalanine, p-methoxy-L-phenylalanine, p-iodo-L-phenylalanine, p-bromo-L-phenylalanine, and L-3-(2-nap

207 no acids: p-amino-L-phenylalanine, p-methoxy-L-phenylalanine, p-iodo-L-phenylalanine, p-bromo-L-pheny

208 n (GFP) with five novel amino acids: p-amino-L-phenylalanine, p-methoxy-L-phenylalanine, p-iodo-L-phe

209 nt protein (sfGFP) containing either p-azido-l-phenylalanine (pAzF) or p-propargyloxy-l-phenylalanine

210 ion for p-acetyl-L-phenylalanine and p-azido-L-phenylalanine (pAzF).

211 orporate the nonnatural amino acid p-benzoyl-L-phenylalanine (pBpa) throughout the transcriptional ac

212 The photo-reactive cross-linker, p-benzoyl-l-phenylalanine (pBpa), was biosynthetically incorporate

213 ith a nonnatural amino acid, p-carboxymethyl-l-phenylalanine (pCMF), we demonstrated that Y54 phospho

214 replacing tyrosine 48 with p-carboxy-methyl-l-phenylalanine (pCMF).

215 le phosphotyrosine analogue (p-Carboxymethyl-L-phenylalanine, pCMF).

216 poly(ethylene glycol)-b-poly(l-histidine-co-l-phenylalanine) (PEGbPHF).

217 nal P-protein, which plays a central role in L-phenylalanine (Phe) biosynthesis, contains distinct ch

218 e diphosphate (ADP), the other substrate, or l-phenylalanine (Phe), the inhibitor.

219 ty cross-linking probe, formyl-Met-p-benzoyl-L-phenylalanine-Phe-Tyr-Lys-epsilon-N-fluorescei n (fMBp

220 S from E.coli in complex with its inhibitor, L-phenylalanine, phosphoenolpyruvate, and metal cofactor

221 ido-l-phenylalanine (pAzF) or p-propargyloxy-l-phenylalanine (pPaF) accumulated in the CFPS solutions

222 c acid diisoamyl ester phenoxy prodrug and a l-phenylalanine propyl ester phosphonobisamidate prodrug

223 Benzoic acid biosynthesis from L-phenylalanine requires shortening of the propyl side c

224 logues incorporating a photolabile p-benzoyl-l-phenylalanine residue in the mid-region and carboxyl-t

225 tagenesis to engineer rhodopsin with p-azido-l-phenylalanine residues incorporated at selected sites,

226 ceratospongamides, which each consist of two L-phenylalanine residues, one (L-isoleucine)-L-methyloxa

227 ProTides with other amino acids, other than L-phenylalanine, showed no detectable activity against H

228 sis of inositol 1,4,5-trisphosphate, whereas l-phenylalanine stimulation of the CaR does not induce a

229 mino acids, we have inserted trifluoromethyl-l-phenylalanine (tfm-Phe) into proteins in vivo at TAG n

230 nged from -4.69+/-0.09kJmol(-1) for N-acetyl-L-phenylalanine to -1.87+/-0.23kJmol(-1) for N-acetyl-L-

231 denylation subunit in a complex with AMP and L-phenylalanine to 1.9 A resolution.

232 m catalyst was used to couple the amino acid l-phenylalanine to a 17-membered lactam, using cross-met

233 , we make use of an azido group of a p-azido-l-phenylalanine to achieve chemical orthogonality.

234 ucleotide-dependent oxidative deamination of L-phenylalanine to form phenylpyruvate and ammonia.

235 regulatory protein (GFRP), where binding of L-phenylalanine to GFRP increases enzyme activities, whi

236 the nonoxidative elimination of ammonia from l-phenylalanine to give trans-cinnamate.

237 AL), an enzyme catalyzing the deamination of L-phenylalanine to initiate phenylpropanoid metabolism.

238 roxylase (PheOH) catalyzes the conversion of L-phenylalanine to L-tyrosine, the rate-limiting step in

239 onversion of phenylalanine and 3,4-dihydroxy-L-phenylalanine to phenylacetaldehyde and dopaldehyde, r

240 ch catalyzes the nonoxidative deamination of l-phenylalanine to trans-cinnamic acid, is ubiquitously

241 EncP, which converts the primary amino acid L-phenylalanine to trans-cinnamic acid.

242 pecific incorporation of a clickable p-azido-L-phenylalanine to Uox and strain-promoted azide-alkyne

243 nd a nonproteinogenic P1 residue (4-guanidyl-l-phenylalanine) to produce a potent (Ki = 1.6 nM) and t

244 histidine and Na+-independent L-arginine and L-phenylalanine transporters.

245 t calcium could directly affect the cellular L-phenylalanine turnover to L-tyrosine.

246 de-containing stereocenter was achieved with l-phenylalanine upon completion of the Mannich cyclizati

247 A significantly more rapid L-phenylalanine uptake and its turnover to L-tyrosine wa

248 entification, with the possible exception of L-phenylalanine utilization as a sole carbon source in t

249 on, a significantly more rapid uptake of 14C-L-phenylalanine was demonstrated in HDPC compared with f

250 The unnatural amino acid para-azido-L-phenylalanine was incorporated into a specific site of

251 In specific examples, m-acetyl-l-phenylalanine was substituted for Lys7 of the cytoplas

252 d, only a single template composed of D- and L-phenylalanines was able to form two strong H-bonds.

253 y incorporated photo-cross-linker (p-benzoyl-l-phenylalanine), we identified a total of 95 and 54 nat

254 ansport and uptake characteristics of [(3)H]-L-phenylalanine were determined at various concentration

255 against protein conjugates of p-amino-D- and L-phenylalanine, were immobilized on a synthetic high-fl

256 tem was extended to the preparation of those L-phenylalanines which are obtained with a low ee value

257 ylene glycol)-b-poly(L-glutamic acid)-b-poly(L-phenylalanine), which effectively co-incorporate cispl

258 illations produced by the CaR in response to l-phenylalanine, which requires the organization of the

259 Titration studies employing benzoate and Z-L-phenylalanine (Z-L-Phe) suggest that indicator monomer