ライフサイエンスコーパス: L-type calcium channel

1 sion of calcium-handling genes (eg, SERCA2a, L-type calcium channel).

2 e the same G406R replacement in the Ca(V)1.2 L-type calcium channel.

3 smembrane Ca(2+) conductance mediated by the L-type calcium channel.

4 rate cardiac repolarization by inhibition of L-type calcium channel.

5 oding the alpha1- and beta2b-subunits of the L-type calcium channel.

6 ity filter, similar to the EEEE locus of the L-type calcium channel.

7 had mutations in genes encoding the cardiac L-type calcium channel.

8 on proteins that control the function of the L-type calcium channel.

9 he recently identified Lp and Ls subtypes of L-type calcium channel.

10 genes encoding subunits of the voltage-gated L-type calcium channel.

11 antagonist at both the NMDA receptor and the L-type calcium channel.

12 e no known selective antagonists of Ca(V)1.3 L-type calcium channel.

13 e effects accompanying general antagonism of L-type calcium channels.

14 All E2-BSA-FITC binding neurons expressed L-type calcium channels.

15 t of Erk1/2 on synaptic transmission through L-type calcium channels.

16 cytosis by increasing calcium influx through L-type calcium channels.

17 to induce intracellular calcium flux through L-type calcium channels.

18 lso binds a unique subpopulation of Ca(v)1.2 L-type calcium channels.

19 olely attributable to calcium influx through L-type calcium channels.

20 ransients mediated by high-voltage-activated L-type calcium channels.

21 reflecting activation of NMDA receptors and L-type calcium channels.

22 vated by calcium entry predominantly through L-type calcium channels.

23 om MAPCs (MAPC-SMCs) demonstrated functional L-type calcium channels.

24 primarily by blocking high-voltage-activated L-type calcium channels.

25 ane depolarization and calcium entry through L-type calcium channels.

26 s in the BLC express the Ca(v)1.2 subtype of L-type calcium channels.

27 pamine receptors and impaired by blockers of L-type calcium channels.

28 nt APPsalpha, or by pharmacological block of L-type calcium channels.

29 attenuated by inhibiting cyclooxygenase-2 or L-type calcium channels.

30 retreatment decreased subsequent activity of L-type calcium channels.

31 rvival of cultured neurons via activation of L-type calcium channels.

32 expression as strongly as did stimulation of L-type calcium channels.

33 elease is mediated by calcium influx through L-type calcium channels.

34 nel blocker, to eliminate the involvement of L-type calcium channels.

35 may in part be mediated by the activation of L-type calcium channels.

36 entate molecular layer, was not dependent on L-type calcium channels.

37 ux of extracellular Ca2+, presumably through L-type calcium channels.

38 and their activities on cardiac and neuronal L-type calcium channels.

39 xicity is prevented by calcium entry through L-type calcium channels.

40 irectly binds and facilitates the opening of L-type calcium channels.

41 receptors are linked to nifedipine-sensitive L-type calcium channels.

42 extracellular fragment APPsalpha and involve L-type calcium channels.

43 y the secreted APPsalpha-domain and involves L-type calcium channels.

44 harmacologically, CaV1.1e behaves like other L-type calcium channels.

45 mate receptors but blocked by antagonists of L-type calcium channels.

46 ecorated by MG53 in a process coordinated by L-type calcium channels.

47 ite ( approximately 27-130 mum) have reduced L-type calcium channels.

48 A(A) receptors is dependent on activation of L-type calcium channels.

49 y AMPA/NMDA receptor-mediated recruitment of L-type calcium channels.

50 d class of antihypertensive drugs that block L-type calcium channels.

51 t contraction and expression and activity of L-type calcium channels.

52 in part via miR-145-dependent regulation of L-type calcium channels.

53 pression is thought to require activation of L-type calcium channels, a view based primarily on studi

54 In neonatal rat cardiomyocytes, L-type calcium channel accessory beta-subunit gene knock

55 ce capable of mediating the knockdown of the L-type calcium channel accessory beta-subunit gene was i

56 These findings indicate that knockdown of L-type calcium channel accessory beta-subunit is capable

57 hypothesized that genetic suppression of the L-type calcium channel accessory beta-subunit would modu

58 ate receptor activation, but rather requires L-type calcium channel activation and functional gap jun

59 These findings suggest a scenario in which L-type calcium channel activation is a crucial switch fo

60 tradiol (E2) induced rapid Ca(2+) influx via L-type calcium channel activation, which was required fo

61 naptic depolarization sufficient to activate L-type calcium channels, activation of postsynaptic meta

62 ning mechanical stress-induced activation of L-type calcium channel activity are obscure.

63 L-type calcium channel activity is critical to afterload

64 potentials presumably results from Ca(V)1.3 L-type calcium channel activity.

65 d as novel contributors to the regulation of L-type calcium channel activity.

66 d as novel contributors to the regulation of L-type calcium channel activity.

67 ggering cell growth in a manner dependent on L-type calcium channel activity.

68 The L type calcium channel agonist (+/-)Bay K 8644 has been

69 eproduction of similar behavior with another L type calcium channel agonist, and the protection affor

70 can be provoked by administration of another L type calcium channel agonist, FPL 64176.

71 The known actions of (+/-)Bay K 8644 as an L type calcium channel agonist, the reproduction of simi

72 Application of the L-type calcium channel agonist Bay K 8644 or activation

73 Conversely, the L-type calcium channel agonist Bay K8644 induced stereot

74 To further verify the mechanism, the L-type calcium channel agonist FPL 64176 was administere

75 ized by chronic treatment with either of the L-type calcium channel agonists FPL 64176 or Bay K 8644.

76 Although most L-type calcium channel alpha(1C) subunits isolated from

77 s required for plasma membrane expression of L-type calcium channels alpha 1S (Cav1.1), probably thro

78 for the cardiac isoform of the voltage-gated L-type calcium channel (alpha(1C)) is elevated in colon

79 e 5' flanking region of exon 1b of the human L-type calcium channel alpha1C gene.

80 In situ hybridization demonstrated that L-type calcium channel alpha1C subunit mRNA expression w

81 Voltage-gated CaV1.2 channels (L-type calcium channel alpha1C subunits) are critical me

82 is demonstrated with simulations of a model L-type calcium channel and a mathematical analysis of a

83 Finally, phosphorylation of the L-type calcium channel and phospholamban were found suff

84 The voltage-gated L-type calcium channel and the functionally linked calci

85 tion of I-2 at S43 appears to be mediated by L-type calcium channels and calcium/calmodulin-dependent

86 arlier reports that the AHNAKs are linked to L-type calcium channels and can be phosphorylated by pro

87 primarily due to the blockade of pancreatic L-type calcium channels and insulin resistance on the ce

88 ked proteins, such as Shank3 and subunits of l-type calcium channels and NMDA receptors, and increase

89 ne NGP1-01, a dual action antagonist at both L-type calcium channels and NMDA receptors, was measured

90 presynaptic silent synapses is dependent on L-type calcium channels and protein kinase A (PKA)/PKC s

91 increases macroscopic inward current through L-type calcium channels and slows activation and deactiv

92 e show that the C. elegans SHN-1/Shank binds L-type calcium channels and that increased and decreased

93 studies demonstrated an association between L-type calcium channels and the sigma-1 receptors.

94 release by two different mechanisms: through L-type calcium channels and through an increase in the p

95 ence of defective current densities for Ik1, l-type calcium channel, and Na(+)/Ca(2+) exchanger.

96 smic reticulum Ca2+-release channel, cardiac L-type calcium channel, and Na+/Ca2+ exchanger.

97 ) is required for normal function of cardiac L-type calcium channels, and its up-regulation is associ

98 sion, culture in NGF reduces the activity of L-type calcium channels, and secondarily, the calcium-se

99 en peroxide microdomain signaling stimulates L-type calcium channels, and that this mechanism strongl

100 acemaker function, including subunits of the L-type calcium channel, Ank2, and Tbx3.

101 describe the first highly selective Ca(V)1.3 L-type calcium channel antagonist and point to a novel t

102 nt study assessed whether treatment with the L-type calcium channel antagonist nimodipine affects the

103 regarding the effect of the well-established L-type calcium channel antagonist nimodipine.

104 Pretreatment of muscle with nifedipine (L-type calcium channel antagonist) marginally decreased

105 s were inhibited by 20 microM nifedipine, an L-type calcium channel antagonist, and 200 nM omega-agat

106 (8), a potent and highly selective Ca(V)1.3 L-type calcium channel antagonist.

107 nist, and the protection afforded by certain L type calcium channel antagonists implicate calcium cha

108 by pretreating the mice with dihydropyridine L type calcium channel antagonists such as nifedipine, n

109 erapamil, D600) and the insensitivity to non-L-type calcium channel antagonists support the conclusio

110 egrees C and found that, at >/=37 degrees C, L-type calcium channels are active at unexpectedly hyper

111 L-type calcium channels are Ca(2+) binding proteins of g

112 Neuronal L-type calcium channels are essential for regulating act

113 Higher levels of L-type calcium channels are in somata/proximal dendrites

114 CaV1 L-type calcium channels are key to regulating neuronal e

115 e details surrounding the mechanism by which L-type calcium channels are privileged in signaling to C

116 dolinium, or nimodipine, which suggests that L-type calcium channels are significant routes of zinc u

117 eleton as well as the inhibition of at least L-type calcium channels as major reasons for the observe

118 atment with nickel ions, by such blockers of L-type calcium channels as nifedipine, verapamil and dil

119 es and probably influx through voltage-gated L-type calcium channels as well.

120 he plasma membrane sodium calcium exchanger, L-type calcium channels, ATP-sensitive K(+) channels, or

121 of EGFP-VSNL was specific to the actions of L-type calcium channels, because CREB signaling after NM

122 The results are consistent with a model of L-type calcium channel biosynthesis in which there are o

123 Nimodipine, an L-type calcium channel blocker has been shown to reduce

124 The L-type calcium channel blocker nifedipine (1 microM) had

125 -operated calcium entry blocked DIR, but the L-type calcium channel blocker nifedipine did not.

126 (+) (K(ATP)) channel opener diazoxide or the l-type calcium channel blocker nifedipine mimicked the e

127 In sharp contrast, the L-type calcium channel blocker verapamil markedly decrea

128 sing this assay, we identified fendiline, an L-type calcium channel blocker, as a specific inhibitor

129 mias could be terminated by nitrendipine, an l-type calcium channel blocker, but not by the Na channe

130 ting pattern, we applied the benzothiazepine L-type calcium channel blocker, diltiazem.

131 The L-type calcium channel blocker, nifedipine, significantl

132 nd La(3+) but not by Mg(2+) or the classical l-type calcium channel blocker, nitrendipine.

133 ently, diabetic mice with cilnidipine, an N-/L-type calcium channel blocker, showed a reduction in al

134 a group of hearts with diltiazem, a specific L-type calcium channel blocker, to eliminate the involve

135 sodilator responses to ketamine, whereas the L-type calcium-channel blocker had no significant effect

136 Other classes of L-type calcium channel blockers did not mislocalize K-Ra

137 First, we observed that the L-type calcium channel blockers nifedipine and verapamil

138 The L-type calcium channel blockers nimodipine and nifedipin

139 al neuroprotective role for centrally acting L-type calcium channel blockers of the dihydropyridine c

140 This study was undertaken to investigate L-type calcium channel blockers of the dihydropyridine c

141 The addition of the L-type calcium channel blockers, 5 microM nifedipine or

142 were calcium spikes, blocked by cadmium and L-type calcium channel blockers.

143 h not only required activation of mGluRs and L-type calcium channels but also was bidirectionally mod

144 group I metabotropic glutamate receptors, or L-type calcium channels, but involves adenosine acting a

145 We found that the activation of L-type calcium channels by 2,5-dimethyl-4-[2-(phenylmeth

146 rapidly reduced the barium currents through L-type calcium channels by approximately 70% and shifted

147 orted by data showing that the activation of L-type calcium channels by BAY-K 8644 was unchanged duri

148 Blocking L-type calcium channels by diltiazem (10 microm) signifi

149 A missense mutation in the L-type calcium channel Ca(V)1.2 leads to LQTS in patient

150 rome is caused by a missense mutation in the L-type calcium channel Ca(v)1.2 that is associated with

151 h one of its ultimate effectors, the class C L-type calcium channel Ca(v)1.2.

152 The link between Ca(2+) influx through the L-type calcium channels Ca(v)1.2 or Ca(v)1.3 and glucose

153 ructure of the skeletal muscle voltage-gated L-type calcium channel (Ca(v)1.1; dihydropyridine recept

154 protein kinase A-mediated phosphorylation of L-type calcium channel (Ca(v)1.2) and phospholamban.

155 xyl-terminal cleavage product of the cardiac L-type calcium channel (Ca(V)1.2) autoregulates expressi

156 The proximal C terminus of the cardiac L-type calcium channel (Ca(V)1.2) contains structural el

157 CT2, amino acids 1596-1692) of human cardiac L-type calcium channel (Ca(V)1.2) have been expressed, r

158 L-type calcium channels (Ca(V)1) are involved in diverse

159 Ca(2+) entry through L-type calcium channels (Ca(V)1.2) is critical in shapin

160 hich encodes the pore-forming subunit of the L-type calcium channel, Ca(v)1.4.

161 channels involved mainly phosphorylation of L-type calcium channels, Ca(2+)-dependent inactivation v

162 Consolidation requires signaling through L-type calcium channels, CaM kinase kinase, and the GluA

163 ight regulation of calcium entry through the L-type calcium channel CaV1.2 ensures optimal excitation

164 1C, the alpha1C subunit of the voltage-gated L-type calcium channel Cav1.2, rank among the most consi

165 The L-type calcium channel CaV1.3 constitutes an important c

166 proteins, only otoferlin interacts with the L-type calcium channel Cav1.3, showing a significant dif

167 S resulted from a recurrent, de novo cardiac L-type calcium channel (CaV1.2) mutation, G406R.

168 Calcium influx through the voltage-dependent L-type calcium channel (CaV1.2) rapidly increases in the

169 The activity and expression of L-type calcium channel (Cav1.2), not T-type calcium chan

170 (2+) and alter the properties of the cardiac L-type calcium channel (CaV1.2).

171 In neurons, L-type calcium channels (CaV1.2 and CaV1.3) regulate an

172 This study investigated regulation of L-type calcium channels (Cav1.2b) by acetylcholine (ACh)

173 Here, we study recombinant neuronal L-type calcium channels, CaV1.2 and CaV1.3.

174 ect plasma membrane targeting of the class C L-type calcium channel complexes is generated as a resul

175 the membrane targeting of voltage-dependent L-type calcium channel complexes.

176 Neuronal L-type calcium channels contribute to dendritic excitabi

177 Thus, selectively antagonizing Ca(V)1.3 L-type calcium channels could provide a means of diminis

178 sely, beta2-AR overexpression did not affect L-type calcium channel current (ICaL) under basal condit

179 SKard cardiomyocytes show hyperactivation of L-type calcium channel current that could not be reverse

180 s a calcium-dependent down-regulation of the L-type calcium channel currents by depolarization.

181 reduction in the amplitude of voltage-gated L-type calcium channel currents in identified retinal bi

182 cal doses, selectively and potently enhances L-type calcium channel currents in isolated rat ventricu

183 50) for nimodipine block of Ca(V)1.3alpha(1) L-type calcium channel currents is 2.7 +/- 0.3 microm, a

184 e neurons from old mice also exhibit smaller L-type calcium channel currents, providing a plausible m

185 The present study found that L-type calcium channel-dependent LTP in the CA3-CA1 hipp

186 Together, these results show that the L-type calcium channel-dependent survival and NMDA recep

187 the relative contribution of calcium through L-type calcium channels differs.

188 trix, that the engagement of plasma membrane L-type calcium channels during normal autonomous pacemak

189 strate CALI of connexin43 (Cx43) and alpha1C L-type calcium channels, each tagged with one or two sma

190 calcium-activated potassium channels and an L-type calcium channel (electrical resonance).

191 of proteins, gamma(1), is a component of the L-type calcium channel expressed in skeletal muscle.

192 L-type calcium channels expressed in the brain are heter

193 segments of Motifs I-IV of the human cardiac L-type calcium channel, expressed in Xenopus oocytes and

194 h muscle, resulted in a similar reduction of L-type calcium channel expression.

195 Basal and stretch-induced L-type calcium channel expressions were both decreased i

196 Transcripts for the L-type calcium channel gene CACNA1C were consistently de

197 7 exclusion activity in a RBFOX2-target, the L-type calcium channel gene, Cacna1c.

198 The predominant class of L-type calcium channels has a Ca(V)1.2 pore-forming subu

199 urthermore, as pharmacological antagonism of L-type calcium channels has been proposed as a potential

200 nt AMPK phosphorylation, while inhibition of L-type calcium channels has no effect.

201 ds was showing the more specific activity on L-type calcium channels, i.e. A7r5 (IC50 = 0.18 +/- 0.02

202 To determine the involvement of the L-type calcium channel in the bursting pattern, we appli

203 a mechanism requiring calcium influx through L-type calcium channels in alphaT3-1 cells and primary r

204 erved role, from fruit flies to mammals, for L-type calcium channels in augmenting motoneuron excitab

205 the present study, we identify a gradient in L-type calcium channels in dendrites of mouse GnRH neuro

206 block of whole cell barium currents through L-type calcium channels in GH4C1 cells show that the com

207 munized mothers exhibited down-regulation of L-type calcium channels in heart.

208 udies attributing an important role to these L-type calcium channels in late onset sporadic Parkinson

209 findings showing that calcium entry through L-type calcium channels in pyramidal cell dendrites in t

210 ts have been used, for example, to implicate L-type calcium channels in the induction of NMDA recepto

211 sed the probability of detecting activity of L-type calcium channels in the T-tubules of ventricular

212 led a significant increase in the density of L-type calcium channels in tottering mouse cerebellum.

213 EGFP-VSNL significantly attenuated L-type calcium channel-induced CREB phosphorylation and

214 pine, an inhibitor of calcium uptake through L-type calcium channels, inhibited the action of NGF on

215 ations but not [Ca(2+)](c) oscillations, and L-type calcium channel inhibition eliminated [Ca(2+)] os

216 restored normal mRNA levels (blocked by the L-type calcium channel inhibitor, nifedipine).

217 on that is responsive to a specific class of L-type calcium channel inhibitors.

218 The L-type calcium channel is the major calcium influx pathw

219 hthalmia-associated transcription factor and L-type calcium channels is severely affected.

220 The activity of L-type calcium channels is tightly coupled to secretion

221 bunit in a well-characterized voltage-gated, L-type calcium channel, is expressed in hair follicle st

222 Ca(V)1.2, the cardiac L-type calcium channel, is important for excitation and

223 bound to the alpha(1) subunit of the cardiac L-type calcium channel, is required for calcium-dependen

224 equires a specific influx of calcium through L-type calcium channels, JNK activation is independent o

225 that, although the density of intracellular L-type calcium channel labeling remains constant through

226 We have previously shown that the L-type calcium channel (LCC) antagonist nilvadipine redu

227 Elevated calcium influx through L-type calcium channels leads to activation of a pathway

228 eightened stimulation, calcium entry through L-type calcium channels leads to activation of the trans

229 Pharmacological blockade of the N- and L-type calcium channel lessens renal injury in kidney di

230 L-type calcium channel (LTCC) and Na(+)/Ca(2+) exchanger

231 l-type calcium channel (LTCC) antagonists have been used

232 G)-like APAs frequently have mutations of an L-type calcium channel (LTCC) CaV1.3.

233 Ca2+ influx through the L-type calcium channel (LTCC) induces Ca2+ release from

234 a critical role for APP in the regulation of L-type calcium channels (LTCC) in GABAergic inhibitory n

235 the expression and distribution profiles of L-type calcium channels (LTCCs) and explored their role

236 neuronal activity in naive rats by engaging L-type calcium channels (LTCCs) and that intra-CeA LTCC

237 Cav1.3 voltage-gated L-type calcium channels (LTCCs) are part of postsynaptic

238 Conversely, L-type calcium channels (LTCCs) become involved in gluta

239 CaV1.3 L-type calcium channels (LTCCs) have been a potential ta

240 L-type calcium channels (LTCCs) play important roles in

241 L-type calcium channels (LTCCs) regulate diverse facets

242 Distinct subpopulations of L-type calcium channels (LTCCs) with different functiona

243 beta-cell replication in vitro by activating L-type calcium channels (LTCCs).

244 nit [Val-Ser-Asn-Leu (VSNL)] is critical for L-type calcium channels (LTCs) to interact with the sign

245 pha(1) subunit of the cardiac isoform of the L-type calcium channel may be a useful marker of colon c

246 This suggests that an L-type calcium channel may participate both short- and l

247 52 protein, as well as antibody targeting of L-type calcium channels may be important in the developm

248 o 39% of neurons by P10-P14, suggesting that L-type calcium channels may contribute to retinocollicul

249 ion is the primary defect in tottering mice, L-type calcium channels may contribute to the generation

250 actory bulb expressing TH and tested whether L-type calcium channels mediate the activity-dependent r

251 r brief depolarization, estradiol attenuated L-type calcium channel-mediated CREB phosphorylation.

252 eta triggered mGluR2/3 signaling, decreasing L-type calcium channel-mediated CREB phosphorylation.

253 L-type calcium channel mRNA was upregulated.

254 iculum Ca(2+) release channel and DHPR is an L-type calcium channel of exterior membranes (surface me

255 ed the impact of mitochondrial regulation of L-type calcium channels on subcellular calcium and react

256 pha1 subunit expression (also referred to as L-type calcium channels or alpha1S pore-forming subunits

257 neuronal activity and enhanced by disrupting L-type calcium channels or elevating cAMP.

258 , AMPA, and ionomycin but not by agonists of L-type calcium channels or of metabotropic glutamate rec

259 In skeletal muscle, L-type calcium channels (or dihydropyridine receptors, D

260 little is known about mechanisms that enable L-type calcium channel participation in neurotransmitter

261 rief input train.SIGNIFICANCE STATEMENT CaV1 L-type calcium channels play a key role in regulating th

262 L-type calcium channels play only a minor role in basal

263 cium release, and verapamil, an inhibitor of L-type calcium channels, preferentially affects T1 B cel

264 ium chelators or inhibitors of voltage-gated L-type calcium channels prevented mitochondrial degradat

265 relative to littermate controls, and alpha1C L-type calcium channel protein levels were significantly

266 hibitors of advanced glycation end products, L-type calcium channels, protein kinase C, Rho-kinase, a

267 intracellular Ca2+ triggers inactivation of L-type calcium channels, providing negative Ca2+ feedbac

268 ound that clonidine interacts with sodium or L-type calcium channels, reduces calcium influx into neu

269 L-type calcium channels regulate a diverse array of cell

270 uge scaffold protein, AHNAK1, interacts with L-type calcium channels, regulates Ca2+ influx, and defe

271 o nucleus signalling, mediated via NMDAR and L-type calcium channels, results in rapid FOXP1 deSUMOyl

272 egulated, whereas the levels of microRNA-29, L-type calcium channel, sarco/endoplasmic reticulum calc

273 calibrated hMSC PS effects on cardiomyocyte L-type calcium channel/sarcoendoplasmic reticulum calciu

274 Accelerated L-currents originated from L-type calcium channels since they were completely block

275 ession and protein levels for calsequestrin, L-type calcium channel, sodium-calcium exchanger, phosph

276 mutation in zebrafish disrupts the alpha1 C L-type calcium channel subunit (C-LTCC).

277 genes ankyrin-3 (ANK3) and voltage-dependent L-type calcium channel subunit beta-3 (CACNB3) as direct

278 Ca(v)1.3 L-type calcium channels sustain the pacemaker current, a

279 sarcomere assembly, whereas mutations in the L-type calcium channel that abort calcium entry do not p

280 electrophysiological evidence implicating an L-type calcium channel that modulates glutamate-induced

281 T-tubules are rich in L-type calcium channels, therefore our work might also p

282 tion mutations in genes encoding the cardiac L-type calcium channel to be associated with a familial

283 kinase Src, and the Calalpha2 subunit of the l-type calcium channel to trigger rapid calcium (Ca(2+))

284 with PDZ domain proteins, are necessary for L-type calcium channels to effectively activate CREB and

285 transgenic mouse with an increased number of L-type calcium channels to identify the role of an incre

286 tective agent by interacting with sodium and L-type calcium channels to reduce the influx of these io

287 The susceptibility of L-type calcium channels to voltage-dependent facilitatio

288 eration was antagonized by the voltage-gated L-type calcium channel (VGLCC) blocker nifedipine, consi

289 Voltage-gated L-type calcium channels (VLCC) are distributed widely th

290 ling, which is independent of influx through L-type calcium channels, was not affected by Dicer KO.

291 Because gadolinium can inhibit both SACs and L-type calcium channels, we perfused a group of hearts w

292 Pharmacological agents selective for L-type calcium channels were employed to assess the role

293 antagonists support the conclusion that only L-type calcium channels were present.

294 neurons by enhancing calcium influx through L-type calcium channels, whereas NMDA receptor-mediated

295 ming alpha(1C) subunit of Ca(v)1.2 channels (L-type calcium channels), whose promoter has 2 binding s

296 L-type calcium channels with a Ca(V)1.3 pore-forming sub

297 Reducing calcium influx through L-type calcium channels with nicardipine also blocked re

298 Direct activation of alphaT3-1 cell L-type calcium channels with the agonist Bay-K 8644 resu

299 xplained by the interaction of the gating of L-type calcium channels with the changes in driving forc

300 KP4 is shown to specifically block L-type calcium channels with weak voltage dependence to