ライフサイエンスコーパス: LBBB

1 LBBB and NICD patients had similar right ventricular tot

2 LBBB patients typically demonstrated (1) a single LV bre

3 LBBB was more frequent after implantation of the Medtron

4 LBBB, intraventricular conduction defect, and RBBB combi

5 LBBB-3 revealed more scar (2 [2-5] segments) compared wi

6 [NA], 14 LBBB) and 25 without CAD (15 NA, 10 LBBB)-were studied.

7 M-34 with CAD (20 normal activation [NA], 14 LBBB) and 25 without CAD (15 NA, 10 LBBB)-were studied.

8 o heart failure patients (narrow QRS [n=18], LBBB [n=11], NICD [n=23]) underwent 3-dimensional electr

9 -1=double-peaked systolic shortening (n=28); LBBB-2=early systolic shortening followed by prominent s

10 al of 111 patients with DCM, 51 with CAD (29 LBBB), and 60 without CAD (30 LBBB) were studied with ec

11 1 with CAD (29 LBBB), and 60 without CAD (30 LBBB) were studied with echocardiography and cardiopulmo

12 In 52 of 66 LBBB VTs, the origin was from the RV perivalvular region

13 th a fall in the QRS duration (NA: r = 0.87; LBBB: r = 0.91), and CO increased with stress (NA by 4.7

14 transient or absent) LBBB after TAVI with a balloon-expandable valve and its

15 ents were performed in 22 dogs, 9 with acute LBBB, 7 with chronic LBBB combined with infarction (embo

16 % ]; P=0.009) increase than BiV-Opt, against LBBB as reference; BiV-Opt and biventricular pacing at A

17 Not all LBBB-morphology EIVA can be dismissed, and not all RBBB-

18 (2 [2-5] segments) compared with LBBB-1 and LBBB-2 (both 0 [0-1], P<0.05).

19 ss I or II and ejection fraction </= 30% and LBBB derive substantial clinical benefit from CRT-D: a r

20 by prominent systolic stretching (n=34); and LBBB-3=pseudonormal shortening with less pronounced late

21 rvedilol was seen in patients with CRT-D and LBBB.

22 In LBBB and LBBB+HF animals, endocardial conduction was approximatel

23 all discriminate effectively between LLk and LBBB populations.

24 well they discriminated between the LLk and LBBB populations.

25 T-D, and those with a QRSD 150 to 179 ms and LBBB had only a modest improvement.

26 e achieved for patients with normal QRSd and LBBB during biventricular and LV pacing.

27 as an independent predictor in both RBBB and LBBB and, in addition, in LBBB, QRS/STT angle and ST J-p

28 ection fraction was similar between RBBB and LBBB patients (24.9% vs. 25.0%; p = 0.98); however, RBBB

29 with a suspected acute coronary syndrome and LBBB for urgent reperfusion therapy.

30 Compared with women with no BBB, LBBB, and intraventricular conduction defect were strong

31 nto left, right, and indetermined-type BBBs (LBBB, RBBB, and intraventricular conduction defect, resp

32 eath was not significantly different between LBBB patients with or without history of IAT (HR: 0.50,

33 mong patients with left bundle branch block (LBBB) (hazard ratio [HR]: 0.58; p < 0.001) and no signif

34 RT-D patients with left bundle branch block (LBBB) (HR: 0.51 [95% CI: 0.35 to 0.76], p < 0.001).

35 nt, T or Q wave or left bundle branch block (LBBB) abnormalities between the prehospital and initial

36 pact of persistent left bundle-branch block (LBBB) after surgical aortic valve replacement.

37 tudy patients with left bundle branch block (LBBB) and 0, 1, 2, or >/=3 comorbidities, including rena

38 Of these, 1175 had left bundle-branch block (LBBB) and 308 had non-LBBB.

39 erized by isolated left bundle branch block (LBBB) and a history of progressive left ventricular (LV)

40 ects of associated left bundle branch block (LBBB) and coronary artery disease (CAD) on peak cardiac

41 etween that during left bundle branch block (LBBB) and LV pacing, reflects optimal resynchronization,

42 ween patients with left bundle-branch block (LBBB) and normal QRSd and if synchrony improved during p

43 mpact of new-onset left bundle branch block (LBBB) and permanent pacemaker implantation (PPI) after t

44 that patients with left bundle branch block (LBBB) be treated with cardiac resynchronization therapy

45 Left bundle branch block (LBBB) causes left ventricular (LV) dyssynchrony which is

46 evelop a transient left bundle-branch block (LBBB) during exercise, but its prognostic significance i

47 RT-D patients with left bundle branch block (LBBB) enrolled in MADIT-CRT (Multicenter Automatic Defib

48 w-onset persistent left bundle branch block (LBBB) in patients undergoing transcatheter aortic valve

49 t arrhythmias with left bundle-branch block (LBBB) morphology.

50 mong patients with left bundle-branch block (LBBB) or longer QRS duration.

51 Patients without left bundle branch block (LBBB) or patients with smaller QRS duration (QRSd) respo

52 ger scar size than left bundle branch block (LBBB) patients do.

53 onary syndrome and left bundle branch block (LBBB) present a unique diagnostic and therapeutic challe

54 n patients without left bundle branch block (LBBB) regardless of patient sex.

55 hearts with acute left bundle branch block (LBBB) showed that endocardial left ventricular (LV) paci

56 cardiac effects of left bundle-branch block (LBBB) using myocardial contrast echocardiography (MCE) t

57 ery wide QRSD with left bundle branch block (LBBB) versus those without LBBB.

58 Left bundle branch block (LBBB) was present in 65 patients, right bundle branch bl

59 re 1281 (70%) with left bundle-branch block (LBBB), 228 (13%) with right bundle-branch block, and 308

60 hic morphology was left bundle branch block (LBBB), and in 15, it was nonspecific intraventricular co

61 ) in patients with left bundle-branch block (LBBB), but the clinical impact of this testing strategy

62 ar, the effects of left bundle branch block (LBBB), coronary artery disease (CAD), and total isovolum

63 t to patients with left bundle branch block (LBBB), heart failure patients with narrow QRS and nonspe

64 tients develop new left bundle-branch block (LBBB), its effect on clinical outcome is unclear.

65 mong patients with left bundle branch block (LBBB), women had a 21% lower mortality risk than men (HR

66 stolic function in left bundle-branch block (LBBB)-failing hearts despite different electrical activa

67 py candidates with left bundle branch block (LBBB)-like electrocardiogram morphology (left ventricula

68 tion, (2) multiple left bundle-branch block (LBBB)-type VTs, and (3) an abnormal endocardial substrat

69 5% of subjects had left bundle-branch block (LBBB).

70 and patients with left bundle branch block (LBBB).

71 ight (RBBB) versus left bundle branch block (LBBB).

72 her complicated by left bundle-branch block (LBBB).

73 (MI) patients with left bundle-branch block (LBBB).

74 c HF patients with left bundle branch block (LBBB).

75 ed dogs with acute left bundle-branch block (LBBB, n=10) and chronic LBBB with tachypacing-induced he

76 patients with non-left bundle branch block (LBBB; including right bundle branch block, intraventricu

77 tion 26+/-7%) with left bundle-branch block (LBBB; QRS duration 174+/-18 ms) were atriobiventricularl

78 ith STEMI or a new left branch bundle block (LBBB), of which 1,654 (60%) presented < or =12 hours.

79 Both LBBB and CAD may do so by prolonging the total isovolumi

80 2.73 [95% CI, 1.78 to 4.13]; P < 0.001), but LBBB-morphology EIVA was not (hazard ratio, 0.82 [CI, 0.

81 changes in ventricular activation induced by LBBB or CAD and is, by itself, a major determinant of pe

82 The t-IVT, CAD, LBBB, and QRS duration were univariate predictors of exe

83 ntional epicardial CRT in compromised canine LBBB hearts.

84 s optimal timing of LV stimulation in canine LBBB hearts.

85 bundle-branch block (LBBB, n=10) and chronic LBBB with tachypacing-induced heart failure (LBBB+HF, n=

86 d concentric remodeling), and 6 with chronic LBBB and heart failure (rapid pacing, LBBB+HF, and eccen

87 n 22 dogs, 9 with acute LBBB, 7 with chronic LBBB combined with infarction (embolization; LBBB plus m

88 locity and pressure, with native conduction (LBBB) and during biventricular pacing at atrioventricula

89 In contrast, LBBB is most commonly caused by nonischemic pathologies.

90 after TAVI is higher in patients who develop LBBB than in patients who do not.

91 %) developed RBBB, but no patients developed LBBB.

92 er reason, then categorized as having either LBBB or no LBBB and QRS duration of either 150 ms or gre

93 LBBB combined with infarction (embolization; LBBB plus myocardial infarction, and concentric remodeli

94 LBBB with tachypacing-induced heart failure (LBBB+HF, n=6).

95 ] index: 0.80 +/- 0.03 vs. 0.58 +/- 0.09 for LBBB, p < 0.04; CURE 0-->1 is dyssynchronous-->synchrono

96 dian difference in CURE-SVD (range, 0-1) for LBBB-HF group versus narrow-QRS-HF group (-0.40; 95% con

97 io, 3.79; confidence interval, 2.95-4.87 for LBBB and hazard ratio, 3.53; confidence interval, 2.14-5

98 al deformation pattern is characteristic for LBBB and results from intraventricular dyssynchrony.

99 inical composite score improved with CRT for LBBB subjects (odds ratio, 0.530; P=0.0034) but not for

100 at AV delays of 40 ms was no different from LBBB.

101 ad LBBB and a QRSd >/=150 ms, 85 (17.1%) had LBBB and QRSd <150 ms, 92 (18.5%) had non-LBBB and a QRS

102 were included in the study; 216 (43.5%) had LBBB and a QRSd >/=150 ms, 85 (17.1%) had LBBB and QRSd

103 On the other hand, LBBB was associated with a higher short-term rate of pac

104 How LBBB-related effects on LV diastolic function may contri

105 septal deformation patterns were identified: LBBB-1=double-peaked systolic shortening (n=28); LBBB-2=

106 In LBBB and LBBB+HF animals, endocardial conduction was app

107 V pacing reduced QRS duration by 21+/-10% in LBBB but only by 5+/-12% in LBBB+HF hearts.

108 n by 21+/-10% in LBBB but only by 5+/-12% in LBBB+HF hearts.

109 r in both RBBB and LBBB and, in addition, in LBBB, QRS/STT angle and ST J-point depression in aVL wer

110 Long-term survival was better in LBBB patients with QRSd >/=150 ms (p = 0.02), but this d

111 tion >/= 140 ms may warrant consideration in LBBB as an indication for further diagnostic evaluation

112 -CRT study, the clinical benefit of CRT-D in LBBB patients was not attenuated by prior history of IAT

113 increase in ejection fraction with CRT-D in LBBB than in non-LBBB patients.

114 ctor (P=0.006) of SPECT perfusion defects in LBBB patients without CAD.

115 Additionally, longer QRS duration in LBBB is associated with better survival in both sexes.

116 rker of diastolic mechanical dyssynchrony in LBBB hearts.

117 However in LBBB, systolic amplitude proved to be the only significa

118 ICD) were significantly (P < 0.001) lower in LBBB patients (0.47; P < 0.001) than in non-LBBB patient

119 Mortality in LBBB and QRS of 150 ms or longer compared with those wit

120 independent predictor of incident HF only in LBBB, with more pronounced risk at QRS >/= 140 ms than a

121 chronization therapy were most pronounced in LBBB-1 and worst in LBBB-3 patients.

122 and MBF reserve is homogeneously reduced in LBBB patients with left ventricular systolic dysfunction

123 pulse conduction was significantly slower in LBBB+HF than in LBBB hearts (67+/-9 versus 44+/-16 ms, r

124 was significantly slower in LBBB+HF than in LBBB hearts (67+/-9 versus 44+/-16 ms, respectively), an

125 vasodilator MCE and SPECT were undertaken in LBBB patients.

126 were most pronounced in LBBB-1 and worst in LBBB-3 patients.

127 r small differences in age, exercise-induced LBBB remained associated with a higher risk of primary e

128 rom the cohort, 70 cases of exercise-induced LBBB were identified.

129 ors of all-cause mortality were TAVI-induced LBBB (hazard ratio [HR], 1.54; confidence interval [CI],

130 TAVI-induced LBBB is an independent predictor of mortality.

131 influence the mortality risk of TAVI-induced LBBB.

132 LV pacing with short AV delay and intrinsic LBBB activation accurately predicted the optimal AV dela

133 Isolated LBBB in animals causes cardiac remodeling due to mechani

134 Inclusion of patients with isolated LBBB-morphology EIVA, which often is idiopathic, may con

135 reased with stress (NA by 4.7 +/- 2.7 l/min; LBBB by 4.0 +/- 2.3 l/min; all p < 0.001).

136 t-IVT became shortened (NA by 7 +/- 3 s/min; LBBB by 9 +/- 4 s/min) and correlated with a fall in the

137 een patients who did and did not develop new LBBB.

138 prior conduction disturbances developed new LBBB following TAVI with a balloon-expandable valve, alt

139 total of 233 patients (34.3%) developed new LBBB.

140 mmend that patients with new or presumed new LBBB undergo early reperfusion therapy, data suggest tha

141 ; adjusted HR, 1.18 [99% CI, 1.10-1.26]), no LBBB and QRS duration of 150 ms or greater (45.7%; HR, 1

142 rd ratio [HR], 1.30 [99% CI, 1.18-1.42]), no LBBB and QRS duration of 150 ms or greater (30.7%; HR, 1

143 30.7%; HR, 1.34 [99% CI, 1.20-1.49]), and no LBBB and QRS duration of 120 to 149 ms (32.3%; HR, 1.52

144 45.7%; HR, 1.16 [99% CI, 1.08-1.26]), and no LBBB and QRS duration of 120 to 149 ms (49.6%; HR, 1.31

145 then categorized as having either LBBB or no LBBB and QRS duration of either 150 ms or greater or 120

146 LBBB and QRS duration less than 150 ms or no LBBB regardless of QRS duration, was associated with low

147 Non-LBBB patients (n=537; 30%) were divided into 2 groups ba

148 with LBBB and QRSd <150 ms (8 +/- 10%), non-LBBB and QRSd >/=150 ms (5 +/- 9%), and non-LBBB and QRS

149 , and dyslipidemia, and had more often a non-LBBB (left bundle branch block) wide QRS complex, and lo

150 benefit was observed in patients with a non-LBBB QRS pattern (right bundle-branch block or intravent

151 < 0.001) and no significant effect among non-LBBB patients (HR: 1.05; p = 0.82, p for the difference

152 CRT-D was significantly increased among non-LBBB patients (HR: 3.62; p = 0.002, p for the difference

153 -LBBB and QRSd >/=150 ms (5 +/- 9%), and non-LBBB and QRSd <150 ms (3 +/- 11%) (p < 0.0001).

154 The latter 2 groups were defined as non-LBBB groups.

155 ta support the use of CRT-D in MADIT-CRT non-LBBB patients with a prolonged PR interval.

156 odds ratio, 0.530; P=0.0034) but not for non-LBBB subjects (odds ratio, 0.724; P=0.21).

157 ad LBBB and QRSd <150 ms, 92 (18.5%) had non-LBBB and a QRSd >/=150 ms, and 103 (20.8%) had non-LBBB

158 nd a QRSd >/=150 ms, and 103 (20.8%) had non-LBBB and QRSd <150 ms.

159 t bundle-branch block (LBBB) and 308 had non-LBBB.

160 however, there was no sex difference in non-LBBB (HR: 0.95; 95% CI: 0.85 to 1.06; p = 0.37).

161 LBBB patients (0.47; P < 0.001) than in non-LBBB patients (1.24; P = 0.257).

162 In non-LBBB patients with a normal PR interval, implantation of

163 In non-LBBB patients with a prolonged PR interval, CRT-D treatm

164 In non-LBBB patients with normal PR, CRT-D therapy was associat

165 y increase subsequent arrhythmic risk in non-LBBB patients.

166 y in CRT-D patients with LBBB but not in non-LBBB patients.

167 tion fraction with CRT-D in LBBB than in non-LBBB patients.

168 ystolic volume index (P<0.0001), whereas non-LBBB patients had smaller decreases (6.7 mL/m(2); P=0.18

169 In patients with non-LBBB and QRS >/=160 ms, the hazard ratio for the primary

170 erter defibrillator-CRT in patients with non-LBBB, especially when the QRS duration is <160 ms.

171 sponse to CRT-D therapy in patients with non-LBBB.

172 oximal LAD occlusions should cause RBBB, not LBBB.

173 elf determined by the presence or absence of LBBB and CAD.

174 Assessment of LBBB contraction pattern was superior to time-to-peak in

175 le, we describe the evolving epidemiology of LBBB in acute coronary syndromes and discuss controversi

176 However, the existence of LBBB-induced cardiomyopathy in humans remains uncertain.

177 andard WMSI, particularly in the presence of LBBB.

178 better than QRS duration or the presence of LBBB.

179 h acute myocardial infarction, regardless of LBBB chronicity, and that a significant proportion of pa

180 50.5 years of age on average at the time of LBBB diagnosis.

181 or the evaluation of the impact of new-onset LBBB and periprocedural PPI post-TAVR were sourced, resp

182 It is unclear whether new-onset LBBB may also impact the prognosis of patients after tra

183 all-cause 1-year mortality and (2) new-onset LBBB on the need for PPI at 1-year follow-up.

184 e the impact of (1) periprocedural new-onset LBBB or PPI post-TAVR on cardiac mortality and all-cause

185 for studies reporting raw data on new-onset LBBB post-TAVR and the need for PPI or mortality at 1-ye

186 New-onset LBBB post-TAVR is a marker of an increased risk of cardi

187 New-onset LBBB post-TAVR was associated with a higher risk of PPI

188 New-onset LBBB was observed in 61 patients (30.2%) after TAVI, and

189 New-onset LBBB was the only factor associated with PPI following T

190 roximal LAD septal perforator caused RBBB or LBBB.

191 fect of evolving ST segment, T or Q waves or LBBB between serially obtained prehospital and hospital

192 hronic LBBB and heart failure (rapid pacing, LBBB+HF, and eccentric remodeling).

193 pulse pressure) compared with atrial pacing-LBBB, and this improvement correlated with mechanical re

194 ft ventricular free wall resulted in pattern LBBB-1.

195 This transformed into pattern LBBB-2 by additionally simulating septal hypocontractili

196 g septal hypocontractility, and into pattern LBBB-3 by imposing additional left ventricular free wall

197 Persistent LBBB at hospital discharge was associated with a decreas

198 ents (group A; 27.4%) developed a persistent LBBB and the remaining 594 (group B; 72.6%) did not.

199 registry of high-volume centers, persistent LBBB after CoreValve Revalving System transcatheter aort

200 associated with a higher rate of persistent LBBB, which in turn determined higher risks for complete

201 7) were independent predictors of persistent LBBB.

202 Patients with persistent LBBB and no PPI at hospital discharge had a higher incid

203 ing CRT-D implantation in clinical practice, LBBB and QRS duration of 150 ms or greater, compared wit

204 tion were compared among patients with RBBB, LBBB, nonspecific LV conduction delay, and QRS <120 ms.

205 nefit was larger in concentrically remodeled LBBB plus myocardial infarction than in eccentrically re

206 l infarction than in eccentrically remodeled LBBB+HF hearts (19% versus 10%).

207 rvations support the existence of a specific LBBB-induced cardiomyopathy resolved by CRT.

208 Use of strict LBBB ECG criteria was not independently associated with

209 Sixty-three symptomatic LBBB patients (group A), 10 left ventricular ejection fr

210 ve reperfusion therapy (13.6% vs. 2.6%) than LBBB patients without chest pain; they were also more li

211 hanical dyssynchrony is induced by RBBB than LBBB in failing hearts, and the corresponding impact of

212 ted with significantly larger scar size than LBBB is, and occlusion of a proximal LAD septal perforat

213 REVERSE demonstrated that LBBB and QRS prolongation are markers of reverse remodel

214 yses and inherent log-rank tests showed that LBBB was not associated with higher all-cause mortality,

215 rams from the LV free wall were later in the LBBB patients in absolute terms (155 ms [SD 23] versus 6

216 In contrast to LBBB patients, narrow QRS and NICD patients are characte

217 ersistent ST-segment elevation as opposed to LBBB or Q waves.

218 Most data pertain to LBBB delays.

219 rain echocardiography (2DSE) may detect true LBBB activation.

220 traction pattern assessment to identify true LBBB activation provided important prognostic informatio

221 Two-thirds of patients (63%) had a typical LBBB contraction pattern.

222 Absence of a typical LBBB contraction was independently associated with incre

223 investigate whether the absence of a typical LBBB mechanical activation pattern by 2DSE was associate

224 d syndrome, including: 1) history of typical LBBB for >5 years; 2) LV ejection fraction (EF) >50%; 3)

225 al 4-chamber view determined whether typical LBBB contraction was present.

226 B, 5+/-2 versus 1+/-1; P=0.0004; NICD versus LBBB, 4+/-2 versus 1+/-1; P=0.001); (2) evidence of earl

227 ior or anterior fascicles: narrow QRS versus LBBB, 5+/-2 versus 1+/-1; P=0.0004; NICD versus LBBB, 4+

228 chrony and impact of CRT in pure RBBB versus LBBB remains largely unknown.

229 90% sensitivity and 82% specificity whether LBBB was present or not.

230 (16 with LBBB), and 25 without CAD (10 with LBBB) were studied.

231 d with resynchronization pacemakers, 13 with LBBB (mean QRS, 171 ms) and 9 with normal QRSd <120 ms (

232 hree patients with DCM, 48 with CAD (16 with LBBB), and 25 without CAD (10 with LBBB) were studied.

233 duration of 150 ms or greater, compared with LBBB and QRS duration less than 150 ms or no LBBB regard

234 of 150 ms or greater (20.9%), compared with LBBB and QRS duration of 120 to 149 ms (26.5%; adjusted

235 of 150 ms or greater (38.6%), compared with LBBB and QRS duration of 120 to 149 ms (44.8%; adjusted

236 Those with RBBB (compared with LBBB) were more likely to have ischemic heart disease (7

237 d more scar (2 [2-5] segments) compared with LBBB-1 and LBBB-2 (both 0 [0-1], P<0.05).

238 In comparison with LBBB, biventricular pacing at separately preidentified h

239 and hemodynamics were obtained in dogs with LBBB-failing hearts during right atrial, LV, and BiV sti

240 In 24 canine hearts with LBBB (12 acute, 6 with heart failure, and 6 with myocard

241 At rest, t-IVT was 8 s/min longer with LBBB (p < 0.001), was unaffected by CAD, and did not cor

242 raction </=35%, QRS duration >/=120 ms) with LBBB by ECG were prospectively included.

243 mortality was 37.8% (n=88) in patients with LBBB and 24.0% (n=107) in patients without LBBB (P=0.002

244 in a community-based cohort of patients with LBBB and acute cardiopulmonary symptoms.

245 nalysis showed that among 1000 patients with LBBB and chest pain, 929 would survive without major str

246 CRT-D patients with LBBB and complete left-sided reverse remodeling had a si

247 ar synchrony) was observed for patients with LBBB and normal QRSd.

248 ar mortality were lowest among patients with LBBB and QRS duration of 150 ms or greater (20.9%), comp

249 mission were also lowest among patients with LBBB and QRS duration of 150 ms or greater (38.6%), comp

250 ection fraction) was better in patients with LBBB and QRSd >/=150 ms (12 +/- 12%) than in those with

251 uggest that only a minority of patients with LBBB are ultimately diagnosed with acute myocardial infa

252 creased significantly in CRT-D patients with LBBB but not in non-LBBB patients.

253 low direction in heart failure patients with LBBB compared to those without LBBB during early but not

254 tal activation time (LVTAT) in patients with LBBB compared with heterogeneous activation sequences an

255 IAT during follow-up in 1,264 patients with LBBB enrolled in the MADIT-CRT (Multicenter Automatic De

256 in-hospital survival of 29,585 patients with LBBB enrolled in the National Registry of MI 2 June 1994

257 Patients with LBBB experienced a 25.3-mL/m(2) mean reduction in left v

258 were acquired in heart failure patients with LBBB or matched patients without LBBB.

259 Nearly half of MI patients with LBBB present without chest pain.

260 m follow-up of MADIT-CRT study patients with LBBB randomized to CRT-D, there were differences in HF o

261 In patients with LBBB receiving implantable cardioverter defibrillator-CR

262 ts with narrow QRS and NICD to patients with LBBB using high-density electroanatomic activation maps.

263 Patients with LBBB were less likely to experience at least one VT/VF e

264 proach among clinically stable patients with LBBB who do not have electrocardiographic findings highl

265 Patients with LBBB who experienced a first VTE had no change in the ri

266 y should be considered for all patients with LBBB who have symptoms consistent with MI.

267 Among patients with LBBB who received CRT-D, mortality is lower in women tha

268 population comprised 533 CRT-D patients with LBBB, 212 (40%) with complete left-sided reverse remodel

269 ts with LLk and 72 consecutive patients with LBBB, all without prior myocardial infarction or sternot

270 In patients with LBBB, there was a continuous relationship between broade

271 Among patients with LBBB, women receiving CRT-D had a lower relative death r

272 Patients with LBBB-morphology EIVAs had a mortality rate (2.5%) simila

273 ated with better survival in both sexes with LBBB and QRS >/=130 ms, whereas there was no clear relat

274 th a lower mortality risk in both sexes with LBBB, although more pronounced among women.

275 ated with better survival in both sexes with LBBB, but not in patients without LBBB.

276 s effect on hearts with RBBB than those with LBBB (i.e., 5.5 +/- 1.1% vs. 29.5 +/- 5.0% increase in d

277 ith an improvement in survival in those with LBBB and a QRSD >/=180 ms (adjusted HR for death: 0.78;

278 95% CI: 0.68 to 0.91), but not in those with LBBB and a QRSD 150 to 179 ms (adjusted HR for death: 1.

279 of 150 ms or longer compared with those with LBBB and QRS of 120 to 129 ms was similar between sexes

280 Sd >/=150 ms (12 +/- 12%) than in those with LBBB and QRSd <150 ms (8 +/- 10%), non-LBBB and QRSd >/=

281 Only among those with LBBB, both sexes had better survival with longer QRS dur

282 Among those with LBBB, patients with a QRSD >/=180 ms had a greater adjus

283 Compared with women with LBBB and QRS of 120 to 129 ms, women with LBBB and QRS o

284 th LBBB and QRS of 120 to 129 ms, women with LBBB and QRS of 140 to 149 ms had a 27% lower mortality

285 s patients with a QRSD 150 to 179 ms without LBBB had no improvement in survival with CRT-D, and thos

286 tients with a QRSD >/=180 ms with or without LBBB, whereas patients with a QRSD 150 to 179 ms without

287 MSI for detecting CAD in DCM with or without LBBB.

288 h LBBB and 24.0% (n=107) in patients without LBBB (P=0.002).

289 ile range, 253-725) days in patients without LBBB (P=0.90).

290 RS duration and survival in patients without LBBB regardless of patient sex.

291 he mortality differences in patients without LBBB were attenuated in both sexes.

292 ere is no sex difference in patients without LBBB, regardless of QRS duration.

293 tients with LBBB or matched patients without LBBB.

294 th p < 0.001) compared with patients without LBBB.

295 sexes with LBBB, but not in patients without LBBB.

296 on fraction-matched control subjects without LBBB and no CAD (group B), and 10 normal control subject

297 patients with LBBB compared to those without LBBB during early but not late diastole.

298 centers in Italy, we analyzed those without LBBB or pacemaker at admission (879 patients [82.9%]).

299 In those without LBBB, the mortality difference was modest and did not di

300 dle branch block (LBBB) versus those without LBBB.