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1 LC-MS and immunoassay can detect protein biomarkers.
2 LC-MS is a high-throughput and low-resource technique th
3 LC-MS-based metabolic phenotyping (metabotyping) in urin
4 LC-MS/MS analysis of stem cell secretome revealed the pr
5 LC-MS/MS analysis showed that the levels of adrenic acid
6 LC-MS/MS and proteomics analysis showed the production o
7 LC-MS/MS assay was developed and validated according to
8 LC-MS/MS data of the extracts revealed several secondary
9 LC-MS/MS methodological development was performed using
10 LC-MS/MS methods developed herein provide powerful tools
11 LC-MS/MS quantification of SULTs is highly reliable meas
12 LC-MS/MS showed a variety of phenolic compounds and stil
13 LC-MS/MS was used to evaluate the proposed sample treatm
15 antification of 100 plasma proteins in >1500 LC-MS runs, the SD range of the retention time during co
16 solid platform for method development in 2D LC-MS protocols in proteomics and peptide retention pred
23 s became the targets in the development of a LC-MS/MS method which underwent a rigorous in-house vali
25 ort, and specific binding assessment using a LC-MS/MS "cold tracer" method, we have identified 8 (PF-
28 ovel strategy using affinity extraction (AE) LC-MS to directly measure drug exposure and target engag
32 down proteomics analysis that consists of an LC-MS feature-finding algorithm, a database search algor
33 nsporters to root exudation, we performed an LC-MS based non-targeted metabolite profiling of semi-po
36 ormed leaf RNA-seq gene expression analysis, LC-MS metabolomics and total phenolics assays in offspri
38 In this study, using a specific antibody and LC-MS/MS methods, we identified 11,976 Khib sites in 3,0
41 ls were monitored by gel electrophoresis and LC-MS/MS to determine the cleavage site(s) and Asn(347)
47 though these analytes are amenable to LC and LC-MS detection an additional major benefit of the SERS
49 studies have been performed using GC/MS and LC-MS as analytical platforms, which involve significant
53 ly, we used tandem affinity purification and LC-MS/MS to search for novel proteins that interact with
55 Integration of RNA-seq data from TCGA and LC-MS/MS proteomics from WS revealed an upregulation of
60 scribe the first restriction-enzyme-assisted LC-MS/MS sequencing study of the influence of methyl cyt
61 Together with the trypsin digestion based LC-MS/MS analysis using surrogate peptides from differen
63 n (ADG), rumen fluid metabolomic analysis by LC-MS and multivariate/univariate statistical analysis w
77 h a (13)C-labeled pooled sample, followed by LC-MS analysis, peak pair picking, and peak intensity ra
81 o compounds by Mnt, which were identified by LC-MS as cyanidin-3-O-rhamnoside and pelargonidin-3-O-rh
83 A total of 2565 proteins was identified by LC-MS/MS analysis (q-value </= 0.01) that accounted for
86 d 11-dehydrocorticosterone) were measured by LC-MS/MS in maternal and cord plasma from 259 Caucasian
88 method allows direct kinetic measurements by LC-MS/MS sequencing for oligonucleotides longer than 20
89 e disulfide structure for murine Meteorin by LC-MS analysis of fragments generated by trypsin plus en
90 tudy was to validate an analytical method by LC-MS for simultaneous determination of mycotoxins and f
94 ost common approach of analyzing proteins by LC-MS is to digest them into peptides, which can serve a
97 tion of noninvasive sweat collection and CIL LC-MS is a robust analytical tool for sweat metabolomics
98 ge analysis of the milk metabolome using CIL LC-MS should be very useful in future research involving
99 differential chemical isotope labeling (CIL) LC-MS for mapping the metabolome profiles of sweat sampl
100 -performance chemical isotope labeling (CIL) LC-MS method for profiling the carbonyl submetabolome wi
103 By following bacterial growth and conducting LC-MS-based assays we show here that YdgR facilitates Ca
104 Variation between this and a conventional LC-MS/MS method using authentic standards for calibratio
105 NIS was 9 times faster than the conventional LC-MS method for determining the concentration of APO-F
107 Design of Experiments (DoE) and a dedicated LC-MS/MS method, the complexity of the different process
109 sion of neurological pathology, we developed LC-MS/MS methods to quantify GlcCer and GlcSph in mouse
110 using targeted metabolomic ((1)H NMR and DI-LC-MS/MS) and proteomic (MALDI-TOF/TOF-MS) platforms.
111 -phase HPLC for purity (99%), peptide digest LC-MS/MS for sequence determination, and circular dichro
117 uber shape regressed on the gene expression, LC-MS, GC-MS and proteomics data sets separately, only g
118 tative proteomics (quadrupole time of flight LC-MS/MS), we analysed the retina of adult longfin wildt
119 s substantially lower with the standard-flow LC-MS (<0.05 minutes) compared with the nanoflow LC-MS m
123 gations, an optimized, sensitive, label-free LC-MS/MS method for multiplex detection of five allergen
125 ECM ligand concentration was derived from LC-MS/MS quantification of the hepatic ECM from mice exp
133 Currently, there is interest in implementing LC-MS in biopharmaceutical HCP profiling alongside conve
138 esults show that (12)C-/(13)C-DnsHz labeling LC-MS is a useful tool for profiling the carbonyl submet
139 r gemcitabine treatment using iTRAQ labeling LC-MS/MS, because it was featured with the advantages of
140 are only experimentally feasible with lower LC-MS/MS detection limits and/or concentrated extracts o
141 ost and preparation time, of peptide mapping LC-MS workflows in protein analytical research, we here
144 -high resolution MS (LC-HRMS), LC-tandem MS (LC-MS/MS) and nuclear magnetic resonance (NMR) spectrosc
145 of top-down liquid chromatography-tandem MS (LC-MS/MS) data sets is rapidly increasing on account of
146 nalysis and liquid chromatography-tandem MS (LC-MS/MS), we selected three high abundance peptide mark
149 specific peptides was monitored by multiplex LC-MS/MS through the parallel reaction monitoring mode o
151 ants, immunoprecipitation combined with Nano LC-MS/MS mass spectrometry was conducted on the erythrol
164 Most software suites allow preprocessing of LC-MS chromatograms to obtain comprehensive information
166 g approach to calculate the selectivities of LC-MS acquisition modes taking mass accuracy, sample mat
169 upplementation were analyzed by GC-MS and/or LC-MS over time courses during nitrogen starvation to ad
170 s, conventional analyses such as HPLC-DAD or LC-MS lose valuable information on metabolite localizati
172 tabolites measured by ultra-high performance LC-MS/GC-MS and retinol concentration (from HPLC) using
174 the use of a porous graphitized carbon (PGC) LC-MS method with effective separation and sensitivity t
175 and analyzed with untargeted reversed phase LC-MS showed that the highest number of metabolite featu
176 al component analysis (PCA) of the processed LC-MS data demonstrated the varying chemical composition
177 RNA-sequencing and quantitative proteomics (LC-MS/MS) to elucidate the role of this chaperone in the
184 quantified in an untargeted high-resolution LC-MS experiment, resulting in 18,556 quantitative mass-
187 e development of a rapid, simple, and robust LC-MS/MS-based enzyme assay using dried blood spots (DBS
189 A simple, rapid, selective and sensitive LC-MS/MS method was developed and validated for the dete
195 chromatography-multistage mass spectrometry (LC-MS(n)) is the most common method for biomonitoring DN
197 rom liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-MS (GC-MS) data relative t
198 ion liquid chromatography-mass spectrometry (LC-MS) and tandem mass spectrometry (MS/MS) to quantify
200 of liquid chromatography-mass spectrometry (LC-MS) data requires the differentiation between a small
201 can liquid chromatography-mass spectrometry (LC-MS) data sets and tailors peak detection for each met
202 on liquid chromatography-mass spectrometry (LC-MS) data, with lung cancer cases at the time of BAL c
203 by liquid chromatography-mass spectrometry (LC-MS) for biomarker determination using ProGastrin Rele
206 vel liquid chromatography-mass spectrometry (LC-MS) interfacing concept is presented and discussed.
207 cal liquid chromatography-mass spectrometry (LC-MS) metabolomics workflow, such as metabolite extract
208 f a liquid chromatography-mass spectrometry (LC-MS) method to separate and quantify R- and S-9-PAHSA,
209 Liquid chromatography-mass spectrometry (LC-MS) methods are most often used for untargeted metabo
210 cal liquid chromatography-mass spectrometry (LC-MS) peaks, enabling real-time browsing of large data
212 gun liquid chromatography-mass spectrometry (LC-MS) proteomic and metabonomic profiling approaches on
213 and liquid chromatography mass spectrometry (LC-MS) with a focus of using dansylation labeling to tar
214 ing liquid chromatography-mass spectrometry (LC-MS), capillary electrophoresis (CE), or gas chromatog
215 rm: liquid chromatography-mass spectrometry (LC-MS), gas chromatography-mass spectrometry (GC-MS), nu
216 ing liquid chromatography mass spectrometry (LC-MS), then the molecular features for respective compo
217 the liquid chromatography-mass spectrometry (LC-MS)-based detection of BPDE-N(2)-dG in BaP-treated ro
218 ted liquid-chromatography-mass spectrometry (LC-MS)-based metabolomics analysis of human biospecimens
219 ng, liquid chromatography-mass spectrometry (LC-MS)-based metabolomics, quality control (QC), molecul
220 ing liquid chromatography-mass spectrometry (LC-MS)-based proteomics, peptidomics, and metabolomics.
224 or liquid chromatography-mass spectrometry (LC-MS); and MS-FINDER 2.0, a structure-elucidation progr
225 uid Chromatography Tandem Mass Spectrometry (LC-MS/MS) analysis of affinity chromatography purified a
226 for the sequential tandem mass spectrometry (LC-MS/MS) analysis of non-polar lipids, polar metabolite
227 uid chromatography tandem mass spectrometry (LC-MS/MS) analysis of the tissues, and quantified relati
228 uid chromatography-tandem mass spectrometry (LC-MS/MS) and constructed a relative release index based
229 uid chromatography-tandem mass spectrometry (LC-MS/MS) and their total amount corresponded to 33% of
230 ography coupled to tandem mass spectrometry (LC-MS/MS) for quantitative measurements of primary metab
231 uid chromatography tandem mass spectrometry (LC-MS/MS) has proven to be a powerful analytical tool fo
232 uid chromatography-tandem mass spectrometry (LC-MS/MS) is an important analytical method for characte
233 uid chromatography-tandem mass spectrometry (LC-MS/MS) is poised to provide a deep understanding of r
234 ography coupled to tandem mass spectrometry (LC-MS/MS) is the main method for high-throughput identif
235 uid chromatography/tandem-mass spectrometry (LC-MS/MS) method to directly assess pyruvate cycling rel
236 uid chromatography-tandem mass spectrometry (LC-MS/MS) method was used with the aim of quantifying mo
237 uid chromatography-tandem mass spectrometry (LC-MS/MS) peptide sequencing (multiplex substrate profil
238 uid chromatography-tandem mass spectrometry (LC-MS/MS) screening for 23 classes of PFASs, followed by
239 sed liquid chromatography-mass spectrometry (LC-MS/MS) to investigate the murine lipidome during norm
240 uid chromatography tandem mass spectrometry (LC-MS/MS) using a high-resolution mass spectrometer.
241 uid chromatography tandem mass spectrometry (LC-MS/MS) was used for collection, identification, and q
242 uid chromatography-tandem mass spectrometry (LC-MS/MS) were developed and validated to quantify the a
243 and liquid chromatography mass spectrometry (LC-MS/MS) were employed for the first time to identify m
244 uid chromatography-tandem mass spectrometry (LC-MS/MS) were used to quantify volatile and ionic PFASs
246 uid chromatography-tandem mass spectrometry (LC-MS/MS), (13)C6-metabolites were radiocalibrated by th
247 uid chromatography tandem mass spectrometry (LC-MS/MS), a widely used method for comparative 'omics a
248 uid chromatography tandem mass spectrometry (LC-MS/MS), qualitative/quantitative structure activity r
249 uid chromatography-tandem mass spectrometry (LC-MS/MS)-based proteomics revealed elongation factor 1
258 uid chromatography tandem mass-spectrometry (LC-MS/MS) have led to the identification of metabolite b
269 r a simple dilution) of the samples into the LC-MS system was also tested, in an attempt to proffer a
274 al activity of the sample extracts using the LC-MS data indicated that high activity in the extracts,
275 up a rapid and accurate method, by using the LC-MS-IT-TOF technology, to detect and quantify CBD, CBD
279 ncreased approximately threefold compared to LC-MS alone due to a combination of the reduction of che
281 AIF had lower selectivities than traditional LC-MS/MS, produced one false positive and did not detect
282 A selectivities were better than traditional LC-MS/MS, showed no bias toward the most intense signals
284 tively supports both targeted and untargeted LC-MS lipidomics, implementing data acquisition, user-fr
286 Therefore we developed a selective bottom-up LC-MS methodology for quantitative gelatin species deter
291 via (Stevia rebaudiana Bertoni) leaves using LC-MS in high resolution mode with a quadrupole-time of
292 The metabolite levels were measured using LC-MS following treatment with colistin (2 mg/L) or dori
293 a complex mixtures of tryptic peptides using LC-MS/MS, showing not only that AI-ETD can nearly double
294 een observed directly in human samples using LC-MS techniques, even though sophisticated methodologie
296 -ligand complex has been explored by UV-Vis, LC-MS, FIR, Fluorescence titration, Job's plot method an
297 Q Orbitrap MS in a simple and efficient way; LC-MS of a trypsin-digested bovine serum albumin (BSA) s
300 ion of the in vivo and chemical studies with LC-MS characterization and assay development also provid
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