ライフサイエンスコーパス: LGE

1 LGE burden was the best predictor of death/VT (area unde

2 LGE CMR of both atria was performed, and NEEES-based ana

3 LGE extent (per 10% increase) corresponded to a 79% incr

4 LGE extent was analyzed with the software GT Volume.

5 LGE imaging and left atrial activation mapping were perf

6 LGE imaging was typical in all patients with cardiac ATT

7 LGE in patients with NICM is associated with increased r

8 LGE is associated with future cardiovascular death and v

9 LGE located subepicardial basal inferolateral was detect

10 LGE of >/=15% of LV mass demonstrated a 2-fold increase

11 LGE scores correlate well with traditional intravascular

12 LGE significantly improved in 16 patients (67%); however

13 LGE was associated with improved prediction of CEs, comp

14 LGE was classified into 3 patterns: none, subendocardial

15 LGE was detected in 61 (27%) patients.

16 LGE was performed with phase-sensitive inversion recover

17 LGE was present in 29% of patients undergoing surgical A

18 LGE was present in 38% of patients.

19 LGE was present in 8 (24%) of the AS patients.

20 LGE-MRI was performed on 426 consecutive patients with A

21 hythmia occurred in 41 LGE-positive versus 0 LGE-negative subjects (annualized incidence, 5.9% versus

22 Cardiovascular mortality occurred in 10 LGE-positive versus 2 LGE-negative subjects (annualized

23 92 patients are described who underwent 100 LGE's during pregnancy.

24 tality occurred in 19 LGE-positive versus 17 LGE-negative subjects (annualized incidence, 3.1% versus

25 ythmia occurred in 64 LGE-positive versus 18 LGE-negative subjects (annualized incidence, 8.8% versus

26 All-cause mortality occurred in 19 LGE-positive versus 17 LGE-negative subjects (annualized

27 rtality occurred in 10 LGE-positive versus 2 LGE-negative subjects (annualized incidence, 1.9% versus

28 iomyopathy (NICM) patients and to evaluate 4 LGE border-zone algorithms.

29 Ventricular arrhythmia occurred in 41 LGE-positive versus 0 LGE-negative subjects (annualized

30 ath or ventricular arrhythmia occurred in 64 LGE-positive versus 18 LGE-negative subjects (annualized

31 6%), T2-weighted imaging, T1 maps, and acute LGE.

32 Acute ECV maps were superior to acute LGE in terms of agreement with final IS.

33 A total of 386 patients (91%) with adequate LGE-MRI scans were included in the study.

34 emain significantly associated with advanced LGE following DRS stratification was stroke or TIA (haza

35 r the primary end point for patients with an LGE extent of 0% to 2.5%, 2.5% to 5%, and >5% compared w

36 g to the extent of LGE (no LGE, LGE<10%, and LGE>/=10%), segmental thickness (>/=15 versus <15 mm), a

37 study sought to evaluate the role of CMR and LGE in the prognosis of AM with preserved LVEF.

38 CMR predictors of CEs were LV dilation and LGE.

39 and cardiac MR risk factors-including EF and LGE.

40 s of left and right ventricular function and LGE burden were measured in 205 patients with left ventr

41 ndings of ventricular fatty infiltration and LGE were frequent and were most often found in those who

42 The combination of FT3 level and LGE provides useful information for assessing the progno

43 urality measured by using native T1 maps and LGE images at 1.5 T and 3 T were compared.

44 1 maps, 15-minute post-contrast T1 maps, and LGE.

45 actions (EFs) and volumes were measured, and LGE was assessed using CMR.

46 underwent CMR (including CMR-MPI, MRCA, and LGE) and x-ray invasive coronary angiography (XA) with f

47 rides were not different in LGE-positive and LGE-negative subjects (P=0.47).

48 vation of Linx either in the prethalamus and LGE or in the neocortex leads to a failure of IC formati

49 examine the relationship between rotors and LGE signal intensity in patients with persistent atrial

50 T2* and T2 maps and T2 STIR and LGE images were acquired.

51 between left atrial conduction velocity and LGE in patients with atrial fibrillation.

52 = -0.18) or bipolar (r = -0.17) voltage and LGE CMR signal intensities with low voltage occurring ac

53 anatomies to allow comparison of voltage and LGE signal intensity.

54 Finally, in multivariable analysis, AS LGE was the best independent CMR predictor of the combin

55 ersy regarding the reproducibility of atrial LGE CMR and its ability to identify gaps in ablation les

56 he corresponding anatomic sites on 469 axial LGE image planes.

57 10 left atria data sets, including 86 axial LGE CMR planes per atrium.

58 continuous relationship was evident between LGE by percent left ventricular mass and SCD event risk

59 We assessed the relation between LGE and cardiovascular outcomes in 1293 HCM patients ref

60 y a weak point-by-point relationship between LGE CMR and endocardial voltage in patients undergoing r

61 n the full cohort (log-rank P<0.001), but bh-LGE did not (log-rank P=0.056) because a significant num

62 In 390 consecutive patients, we collected bh-LGE and moco-LGE with identical image matrix parameters.

63 In 41 patients, bh-LGE was abandoned because of image quality issues, inclu

64 er of vulnerable patients did not receive bh-LGE (because of arrhythmia or inability to hold breath).

65 of the SCD event risk model was enhanced by LGE (net reclassification index, 12.9%; 95% confidence i

66 ntinuous net reclassification improvement by LGE markers.

67 evaluate the prognostic role of LGE by CMR (LGE-CMR) imaging in patients with NICM.

68 al validation of SRM was performed comparing LGE-MRI with surgical biopsy.

69 lective inversion pulse used in conventional LGE, which results in the hyperintensity artifact.

70 The conventional LGE MR imaging pulse sequence was modified by replacing

71 ed LGE sequence, along with the conventional LGE sequence, was evaluated in 12 patients with implanta

72 In 10 of the 12 patients, the conventional LGE technique produced severe, uninterpretable hyperinte

73 cephalon with the exception of the dorsal (d)LGE, we found that the increase in cortical OPCs in Gsx2

74 lar zone of the lateral ganglionic eminence (LGE) at embryonic day 13.5 may underlie such deficits by

75 icularly in the lateral ganglionic eminence (LGE) caudal ganglionic eminence (CGE), and septum, inclu

76 tivin A induces lateral ganglionic eminence (LGE) characteristics in nascent neural progenitors deriv

77 es derived from lateral ganglionic eminence (LGE) progenitors at specific embryonic time points.

78 The technique may enable LGE MR imaging in patients with cardiac devices, in whom

79 maging, including contrast material-enhanced LGE imaging and T1 mapping.

80 Late-gadolinium-enhanced (LGE) cardiac MRI (CMR) is a powerful method for characte

81 ted sequences, and late gadolinium-enhanced (LGE) segmented two-dimensional inversion-recovery turbo

82 netic resonance late gadolinium enhancement (LGE) and feature-tracking are capable of noninvasive qua

83 Patients with late gadolinium enhancement (LGE) and low lateral MAPSE had significantly reduced sur

84 nce (CMR), with late gadolinium enhancement (LGE) and T1 mapping, is emerging as a reference standard

85 dict dynamic of late gadolinium enhancement (LGE) as persistent LGE has been shown to be a risk marke

86 terization with late gadolinium enhancement (LGE) as well as T1 and T2 mapping enable accurate diagno

87 he influence of late gadolinium enhancement (LGE) assessed by cardiovascular magnetic resonance on le

88 ve analysis and late gadolinium enhancement (LGE) assessments and analyzed the following LVNC diagnos

89 replacement and late gadolinium enhancement (LGE) at cardiac magnetic resonance (MR) imaging in patie

90 Late gadolinium enhancement (LGE) border zone on cardiac magnetic resonance imaging h

91 have shown that late gadolinium enhancement (LGE) by cardiac magnetic resonance (CMR) can detect foca

92 the ability of late gadolinium enhancement (LGE) by cardiac magnetic resonance imaging (MRI) to pred

93 Late gadolinium enhancement (LGE) by cardiac MR (CMR) is a predictor of adverse cardi

94 ionship between late gadolinium enhancement (LGE) cardiac magnetic resonance (CMR) signal intensity a

95 Late gadolinium enhancement (LGE) cardiovascular magnetic resonance (CMR) imaging can

96 tigated whether late gadolinium enhancement (LGE) cardiovascular magnetic resonance identified patien

97 sis detected by late gadolinium enhancement (LGE) cardiovascular magnetic resonance predicts outcomes

98 c resonance for late gadolinium enhancement (LGE) detection and quantification and prospectively foll

99 rction (STEMI), late gadolinium enhancement (LGE) has been demonstrated to overestimate MI size and T

100 resonance with late gadolinium enhancement (LGE) has emerged as an in vivo marker of myocardial fibr

101 nance (CMR) and late gadolinium enhancement (LGE) has not been clarified in acute myocarditis (AM) wi

102 nal left atrial late gadolinium enhancement (LGE) heterogeneity on magnetic resonance imaging.

103 Late gadolinium enhancement (LGE) imaging overestimates acute infarct size.

104 ction (ECV) and late gadolinium enhancement (LGE) in children and young adults with congenital aortic

105 entricular (LV) late gadolinium enhancement (LGE) in patients with atrial fibrillation (AF).

106 resonance with late gadolinium enhancement (LGE) is a reference standard for the diagnosis of cardia

107 cluding MPI and late gadolinium enhancement (LGE) is not well established.

108 was detected by late gadolinium enhancement (LGE) MRI, and myocardial perfusion/metabolism was evalua

109 e imaging (MRI) late gadolinium enhancement (LGE) of the coronary vessel wall can detect and grade co

110 l/midmyocardial late gadolinium enhancement (LGE) on contrast-enhanced cardiac magnetic resonance (gr

111 t CMR including late gadolinium enhancement (LGE) parameters between 2002 and 2015 and were included

112 the presence of late gadolinium enhancement (LGE), (2) quantify their risk of death/ventricular tachy

113 F who underwent late gadolinium enhancement (LGE)-cardiac magnetic resonance imaging to quantify LA f

114 resonance with late gadolinium enhancement (LGE); all 3 tests were <24 hours apart.

115 enhancement on late gadolinium enhancement [LGE] images >20%, n = 72) or small (enhanced volume </=2

116 brosis imaging (late gadolinium enhancement [LGE]), and (1)H magnetic resonance spectroscopy were per

117 and myocardial late gadolinium enhancement [LGE]), and metabolic parameters (hepatic proton-density

118 ts are superior with moco-LGE, which extends LGE-based risk stratification to include patients with v

119 Extensive LGE measured by quantitative contrast enhanced CMR provi

120 SRM is identified on LGE-MRI, and extensive LGE (>/=30% LA wall enhancement) predicts poor response

121 ized event rates for mortality were 4.7% for LGE+ subjects versus 1.7% for LGE- subjects (P=0.01), 5.

122 were 4.7% for LGE+ subjects versus 1.7% for LGE- subjects (P=0.01), 5.03% versus 1.8% for heart fail

123 compared to women that had an indication for LGE but in whom LGE was not performed because of pregnan

124 erwent cardiovascular magnetic resonance for LGE evaluation.

125 Forty-one of 205 patients (20%) had LGE; 12 of 205 (6%) died or had VT during follow-up; of

126 Seventeen of the 43 patients (39%) had LGE patterns consistent with myocardial infarction.

127 Crucially, these human LGE progenitors readily differentiate into postmitotic n

128 ICM patients with primary prophylactic ICD, LGE border zone predicted ICD therapy in univariable and

129 d right ventricular dysfunction can identify LGE+ patients at highest risk of death/VT.

130 Among the 374 patients with suitable images, LGE involved the subepicardial layer inferior and latera

131 zing laboratory markers experienced improved LGE, in a small percentage LGE worsened.

132 In LGE-positive patients, there was an increase in LGE exte

133 Change in LGE >20% was considered significant.

134 arkers at baseline did not predict change in LGE at 3 months.

135 ocardial triglycerides were not different in LGE-positive and LGE-negative subjects (P=0.47).

136 The increase in LGE extent during follow-up was associated with progress

137 -positive patients, there was an increase in LGE extent over time (P=0.034), which was inversely rela

138 rd ratios were calculated per 1% increase in LGE.

139 (adjusted hazard ratio, 1.80/10% increase in LGE; P<0.03).

140 (adjusted hazard ratio, 1.46/10% increase in LGE; P=0.002), even after adjustment for other relevant

141 Increased LGE burden and right ventricular dysfunction can identif

142 In multivariable analysis, increased LGE was associated with lower LA passive emptying fracti

143 sus 49+/-13 mL/m(2); P=0.036), and increased LGE (27.1+/-11.7% versus 36.8+/-14.8%; P<0.001).

144 ex, diabetes, LV end-diastolic volume index, LGE, EF) (hazard ratio = 2.051 per mm decrease; 95% conf

145 ing patients with stage IV versus stage I LA LGE was 1.67 (95% confidence interval: 1.01 to 2.76) for

146 ere stratified according to Utah stage of LA LGE criteria, and observed for the occurrence of MACCE,

147 ve analysis demonstrated that more severe LA LGE is associated with increased MACCE risk, driven prim

148 ethod of assessing gaps in ablation lesions, LGE CMR is unable to reliably predict sites of electrica

149 Healthy volunteers had less LGE and higher LA functional parameters compared with pa

150 ss (>/=15 versus <15 mm), and segmental LGE (LGE versus non-LGE).

151 ated according to the extent of LGE (no LGE, LGE<10%, and LGE>/=10%), segmental thickness (>/=15 vers

152 es were RV fatty infiltration (28.9%) and LV LGE (35.5%).

153 Isolated nonischemic LV LGE with a stria pattern may be associated with life-thr

154 In patients with AM and preserved LVEF, LGE in the midwall layer of the AS myocardial segment is

155 The mean LGE burden for left atrium and right atrium was 23.9+/-1

156 Midwall LGE identifies a group of patients with dilated cardiomy

157 ing location and pattern, septal and midwall LGE showed strongest associations with MACE (HR: 2.55; 9

158 investigated the association between midwall LGE and the prespecified primary composite outcome of SC

159 Moco-LGE significantly stratified risk in the full cohort (lo

160 utive patients, we collected bh-LGE and moco-LGE with identical image matrix parameters.

161 ully scanned patients are superior with moco-LGE, which extends LGE-based risk stratification to incl

162 In the multivariable model, LGE presence maintained significant association with MAC

163 The modified LGE sequence, along with the conventional LGE sequence,

164 After a median follow-up of 46 months, LGE-positive and FT3 < 2.77 pg/mL was identified as the

165 Integration of MRCA with CMR-MPI/LGE further improved CMR performance to 96% sensitivity,

166 CMR-MPI/LGE had 79% sensitivity, 95% specificity, positive predi

167 of a comprehensive 1.5-T stress-rest CMR-MPI/LGE protocol at a cost of longer scanning times.

168 e-heart MRCA integration into a 1.5T CMR-MPI/LGE protocol for the detection of functionally significa

169 Late-gadolinium-enhancement cardiac MRI (LGE-MRI) assessment of atrial fibrosis helps in selectin

170 esized that late gadolinium enhancement MRI (LGE-MRI) can identify left atrial (LA) wall structural r

171 sity ratio defined as left atrial myocardial LGE signal intensity divided by the mean left atrial blo

172 e detection and quantification of myocardial LGE in patients with previous myocardial infarction was

173 athletes with ventricular arrhythmias and no LGE (group B) and 40 healthy control athletes (group C).

174 estigated according to the extent of LGE (no LGE, LGE<10%, and LGE>/=10%), segmental thickness (>/=15

175 group), and it was absent in 26 patients (no-LGE group).

176 s <15 mm), and segmental LGE (LGE versus non-LGE).

177 In NICM patients, total LGE but not LGE border zone had predictive value for ICD therapy.

178 tion (bias range, -0.34 to 0.40; P > .05) of LGE.

179 e (60% of LGE-positive patients and 12.5% of LGE-negative patients).

180 ad indicators for conduction disease (60% of LGE-positive patients and 12.5% of LGE-negative patients

181 athic dilated cardiomyopathy, the absence of LGE at baseline is a strong independent predictor of LV-

182 Absence of LGE was associated with lower risk for SCD events (adjus

183 d with the McNemar test, and the accuracy of LGE quantification was calculated with the paired t test

184 Addition of LGE to age and left ventricular ejection fraction improv

185 The area of LGE measured with synthetic IR techniques showed excelle

186 /VT were associated with a greater burden of LGE (14+/-11 versus 5+/-5%, P<0.01) and right ventricula

187 The degree of LGE was quantified.

188 Detection of LGE by CMR has excellent prognostic characteristics and

189 -sensitive IR techniques in the detection of LGE were 90% and 95%, respectively, with patient-based a

190 were investigated according to the extent of LGE (no LGE, LGE<10%, and LGE>/=10%), segmental thicknes

191 Extent of LGE also predicted the development of end-stage HCM with

192 The AS group had a greater extent of LGE and a higher LV end-diastolic volume index than othe

193 The presence and extent of LGE relate to overall cardiovascular outcome in cardiomy

194 f regional association between the extent of LGE signal intensity and the presence of rotors.

195 Extent of LGE was associated with an increased risk of SCD events

196 he extent of LGE; in contrast, the extent of LGE was associated with the extent of hypertrophy.

197 e model for mortality, age and the extent of LGE were independent predictors of mortality.

198 ics showed no association with the extent of LGE; in contrast, the extent of LGE was associated with

199 determine whether size and heterogeneity of LGE predict appropriate implantable cardioverter defibri

200 stics curve, 0.80); for every 1% increase of LGE burden, the hazard of death/VT increased by 8%.

201 ted with the extent and anatomic location of LGE signal intensity from CMR.

202 oup C; P<0.001), whereas a spotty pattern of LGE localized at the junction of the right ventricle to

203 nts with cardiac amyloidosis, the pattern of LGE was always typical for amyloidosis (29% subendocardi

204 iate Cox analysis identified the presence of LGE (hazard ratio: 2.8; 95% CI: 1.3 to 6.9; p = 0.025) a

205 ndependently associated with the presence of LGE (OR: 0.140, 95% CI: 0.035-0.567), perfusion abnormal

206 The presence of LGE also predicted higher all-cause mortality (p = 0.05)

207 The presence of LGE indicating focal fibrosis or unrecognized infarct by

208 In surgical AVR, the presence of LGE predicted higher post-operative mortality (odds rati

209 ysis demonstrated that segmental presence of LGE was associated with additional attenuation in myocar

210 on, LV systolic dysfunction, and presence of LGE.

211 ling rates as well as a higher prevalence of LGE compared with healthy control subjects.

212 ment for the detection and quantification of LGE was analyzed with kappa and Bland-Altman statistics,

213 -analysis to evaluate the prognostic role of LGE by CMR (LGE-CMR) imaging in patients with NICM.

214 The role of LGE-CMR in the risk stratification of dilated cardiomyop

215 nary artery disease, either transmurality of LGE or contractile reserve in response to dobutamine can

216 r studies looking at the prognostic value of LGE-CMR in patients with NICM.

217 Atrial SRM is identified on LGE-MRI, and extensive LGE (>/=30% LA wall enhancement)

218 compared with 93 (30%) rated as infarcted on LGE images and with 90 (29%) rated as infarcted on cine

219 ter agreement with final IS than acute IS on LGE (ECV maps: bias, 1.9; 95% CI, 0.4-3.4 versus LGE ima

220 ity artifacts that are typically observed on LGE images in patients with implanted cardiac devices ar

221 ical biopsy specimens correlated with SRM on LGE-MRI.

222 tients without dilated cardiomyopathy and/or LGE.

223 ), compared with none of athletes with no or LGE spotty pattern and controls.

224 nd other segments in 59 patients (16%; other-LGE group), and it was absent in 26 patients (no-LGE gro

225 atty infiltration and/or nonischemic pattern LGE).

226 erienced improved LGE, in a small percentage LGE worsened.

227 e gadolinium enhancement (LGE) as persistent LGE has been shown to be a risk marker in myocarditis.

228 expression of Meis1, a marker of postmitotic LGE neurons.

229 or atrial tachycardia underwent preablation LGE CMR.

230 served in primary cell cultures of Rarb(-/-) LGE.

231 uperior to magnitude-only inversion recovery LGE because PSIR always nulled the tissue (blood or myoc

232 atory parameters do not sufficiently reflect LGE in myocarditis.

233 RV LGE was present in 31 (56%) patients.

234 In bivariate analysis, RV LGE presence was independently associated with the compo

235 with cardiac events after controlling for RV LGE (hazard ratio, 0.80 [95% confidence interval, 0.68-0

236 icular tachyarrhythmia, 1 death) included RV LGE presence and extent, RV volumes/mass/ejection fracti

237 agreement between location and extent of RV LGE at in vivo cardiovascular magnetic resonance and his

238 Systemic RV LGE is strongly associated with adverse clinical outcome

239 There was RV LGE progression in a different case restudied for clinic

240 fferences in the per-patient and per-segment LGE detection rates between the synthetic and convention

241 ickness (>/=15 versus <15 mm), and segmental LGE (LGE versus non-LGE).

242 wo hundred ninety-four (44%) patients showed LGE presence, which was associated with a more than doub

243 None of the study patients showed LGE.

244 The majority of athletes with no or spotty LGE pattern had ventricular arrhythmias with a predomina

245 A stria LGE pattern with subepicardial/midmyocardial distributio

246 with transitions from none to subendocardial LGE at an extracellular volume of 0.40 to 0.43 (AL) and

247 The use of T1 mapping to derive synthetic LGE images may reduce imaging times and operator depende

248 te of death/VT per year was >20x higher than LGE- (4.9 versus 0.2%, P<0.01); (2) death/VT were associ

249 Improvement chi(2) analysis disclosed that LGE addition to models, including clinical data alone or

250 Multivariate analysis showed that LGE was associated with high likelihood of composite end

251 This allowed the LGE signal intensity to be projected onto the anatomy fr

252 d by reduced neuronal differentiation in the LGE of Meis1(-/-) embryos.

253 In the LGE+ group (1) the rate of death/VT per year was >20x hi

254 ng follow-up; of these, 10 (83%) were in the LGE+ group.

255 th primary prevention ICD by quantifying the LGE border zone.

256 a temporal and etiological relation with the LGE.

257 death/VT in the entire group and within the LGE+ group was determined using Cox proportional hazard

258 in transposition of the great arteries, thus LGE cardiovascular magnetic resonance should be incorpor

259 cardiovascular disease related) according to LGE-CMR status in 154 consecutive AS patients (96 men; m

260 ast agents at 3 T could be an alternative to LGE CMR for characterizing chronic MIs using a canine mo

261 CE rates were 4.8% and 2.1% corresponding to LGE presence and absence, respectively (p < 0.001).

262 d infarct size and transmurality relative to LGE images in AMI (P=0.016 and P=0.007, respectively), w

263 d infarct size and transmurality relative to LGE images in AMI and CMI (P<0.001) at 1.5 T.

264 For NICM, total LGE by all 4 methods was the strongest predictor (hazard

265 In NICM patients, total LGE but not LGE border zone had predictive value for ICD

266 Transmural LGE is determined reliably by PSIR and represents advanc

267 Transmural LGE predicted death (hazard ratio, 5.4; 95% confidence i

268 omes did not differ between women undergoing LGE during pregnancy, compared to women that had an indi

269 Ten healthy control subjects also underwent LGE MRI.

270 119 patients with AL amyloidosis, underwent LGE cardiovascular magnetic resonance.

271 HODS AND ICM and NICM patients who underwent LGE cardiac magnetic resonance imaging prior to ICD impl

272 2014 involving pregnant women who underwent LGE for any indication were included.

273 -five patients (aged 27+/-7 years) underwent LGE cardiovascular magnetic resonance and were followed

274 Follow-up LGE imaging was used as the reference standard for final

275 of MI on nonenhanced cine MR images by using LGE imaging as the standard of reference.

276 LV fibrosis was detected by using LGE in 11 cases.

277 71% transmural), including right ventricular LGE (96%).

278 (ECV maps: bias, 1.9; 95% CI, 0.4-3.4 versus LGE imaging: bias, 10; 95% CI, 7.7-12.4).

279 hundred and ninety-nine patients (29%) were LGE positive.

280 ovement was 0.39 (95% CI: 0.10 to 0.67) when LGE presence was added to the multivariable model for MA

281 This study was conducted to evaluate whether LGE-CMR can predict post-operative survival in patients

282 ng in patients with cardiac devices, in whom LGE MR imaging otherwise could not be used for diagnosis

283 n that had an indication for LGE but in whom LGE was not performed because of pregnancy.

284 The modified wideband LGE MR imaging technique eliminates the hyperintensity a

285 cts were eliminated with use of the wideband LGE sequence, thereby enabling confident evaluation of m

286 an age 50 years, median LVEF 50%, 25.3% with LGE) followed for a median of 4.6 years, 18 of 101 (17.8

287 Assessment of midwall fibrosis with LGE-CMR imaging provided independent prognostic informat

288 c involvement who underwent cardiac MRI with LGE with at least 12 months of either prospective or ret

289 Sarcoidosis patients with LGE are at significant risk for death/VT, even with pres

290 Patients with LGE had greater risk of developing CHF than patients wit

291 Patients with LGE had increased overall mortality (odds ratio, 3.27; P

292 Thirty-one of 61 (51%) patients with LGE reached combined end point when compared with 18 of

293 f 4.6 years, 18 of 101 (17.8%) patients with LGE reached the prespecified end point, compared with 7

294 f FT3, decreased percentage of segments with LGE and perfusion/metabolism abnormalities were found.

295 ntly reduced survival compared to those with LGE and high lateral MAPSE (log-rank P < .0001).

296 ments>/=15 mm in thickness and in those with LGE; adjusted analysis demonstrated that segmental prese

297 mpared with 18 of 167 (11%) patients without LGE (hazard ratio, 5.10 [2.78-9.36]; P<0.001).

298 risk of developing CHF than patients without LGE (hazard ratio, 5.23 [2.61-10.50]; P<0.001) and highe

299 % to 5%, and >5% compared with those without LGE were 10.6 (95% CI, 3.9-29.4), 4.9 (95% CI, 1.3-18.9)

300 5.32; P<0.00001) compared with those without LGE.