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1 maximal stimulation of the G protein-coupled LH receptor.
2 of the FSH receptor and the TM region of the LH receptor.
3 tivation have been identified in the TSH and LH receptors.
4 ed the TSH receptor but not the CG/lutropin (LH) receptor.
5 nt studies suggest that luteinizing hormone (LH) receptor activation leads to trans-activation of epi
7 ucing cAMP, co-expression with the truncated LH receptor allowed partial restoration of ligand signal
8 ic receptor containing the ectodomain of the LH receptor and transmembrane region of fly LGR2 was rep
9 ts the lateral motions of antagonist binding LH receptors, and that receptor surface densities must b
10 as interactions between these domains of the LH receptor are permissive for constitutively activating
12 eptor with only TM V and VI derived from the LH receptor can be rendered constitutively active by the
17 idual FLAG-tagged human luteinizing hormone (LH) receptors expressed on CHO cells and native LH recep
20 been identified in the luteinizing hormone (LH) receptor gene, leading to constitutive activation of
21 at LH receptors (rLHRs), but hCG binds human LH receptors (hLHRs) 1000-10,000 fold better than bLH.
22 tion in the i3 to identify the region in the LH receptor important for its constitutive activation.
23 on and indicate the importance of TM1 of the LH receptor in the proper orientation of the EC ligand b
24 results suggest that the hinge region of the LH receptor interacts with exoloop 2 to constrain the re
27 Similar to LH receptors labeled with Au-hCG, LH receptors labeled with gold-deglycosylated hCG, an hC
28 eceptors containing only TM V to VI from the LH receptor led to major increases in ligand-independent
29 convert the noncleaving luteinizing hormone (LH) receptor (LHR) into a cleaved, two-subunit molecule.
30 were 3betaHSD-negative, luteinizing hormone (LH) receptor (LHR)-negative, and platelet-derived growth
33 t analysis showed an inverse relationship to LH receptor mRNA levels during different physiological s
35 nt study, we isolated and characterized this LH receptor mRNA-binding protein (LRBP) from rat ovary.
41 receptors expressed on CHO cells and native LH receptors on both KGN human granulosa-derived tumor c
42 mpared with LH receptors on untreated cells, LH receptors on cells treated with 100 nm hCG exhibit re
48 resides in the hinge region of fly LGR2 with LH receptor sequences led to constitutive receptor activ
50 and exoloop 2, but not exoloop 1 or 3, from LH receptors showed decreases in constitutive activity,
51 llicles but not MA-10 cells, suggesting that LH receptor signaling activates the EGFR by different me
52 tical downstream target of G-protein-coupled LH receptor signaling and one of the first transcription
55 d LH receptor with an N-terminally truncated LH receptor that lacked the EC ligand binding domain als
56 -expression of the anchored EC region of the LH receptor together with the N-terminally truncated rec
57 ddition, co-expression of the same truncated LH receptor with an N-terminally truncated LH receptor t
58 e that binding of hCG induces aggregation of LH receptors within nanoscale, cell surface membrane com
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