ライフサイエンスコーパス: LPS receptor

1 (TLR4) and LPS and is a critical part of the LPS receptor.

2 nly two signalling pathways emanate from the LPS receptor.

3 R4 carbohydrates in LPS cross-linking to the LPS receptor.

4 logical activity, appears to be a functional LPS receptor.

5 a 55-kDa protein, has been identified as an LPS receptor.

6 ugh membrane CD14 (mCD14), a proinflammatory LPS receptor.

7 3 (polyinosinic-polycytidylic acid) or TLR4 (LPS) receptor.

8 ophages through the CD14 lipopolysaccharide (LPS) receptor.

9 fy components of the putatively shared Taxol/LPS receptor, a novel, photoactivatable Taxol analogue w

10 lthough CD14 has been identified as the main LPS receptor, accumulating evidence has suggested the po

11 n lipid A and TLR4 are essential for optimal LPS receptor activation.

12 receptor 4 (Tlr4) is the lipopolysaccharide (LPS) receptor and biochemical evidence that Tlr4 confers

13 eracts with ligand-binding protein and CD14 (LPS receptor) and activates expression of inflammatory g

14 formation required CD14 (a component of the LPS receptor) and NFAT.

15 the patient's monocytes expressed CD14, the LPS receptor, and bound LPS in a specific manner, but fa

16 uman neutrophils occurs via CD14, a proposed LPS receptor, and requires the presence of plasma contai

17 l. report that caspases 4/5/11 are cytosolic LPS receptors, becoming activated through oligomerizatio

18 Zanoni et al. (2017) show that the LPS receptor CD14 promotes internalization of oxidized p

19 a high affinity to monocytes but not to the LPS receptor CD14, and experiments performed at 4 degree

20 n HBP and LPS and their interaction with the LPS receptor CD14.

21 ine induction, and surface expression of the LPS receptor CD14.

22 ing expression of either lipopolysaccharide (LPS) receptor CD14 or myeloid differentiation protein-88

23 The monocyte/macrophage lipopolysaccharide (LPS) receptor CD14 was also assessed.

24 by overexpression of the lipopolysaccharide (LPS) receptors CD14 and TLR4, which antagonize each othe

25 if LPS stimulation was mediated through the LPS receptor, CD14, surface receptors on HGF were assess

26 While two LPS receptors, CD14 and CD11/CD18, have been associated

27 showed that monocytic TM interacted with the LPS receptors, CD14 and TLR4/myeloid differentiation fac

28 signaling was unrelated to the expression of LPS receptors, CD14, or toll-like receptor 4.

29 Prior to LPS-stimulation, the LPS-receptor cluster-of-differentiation 14 (CD14) and To

30 anscription factors, is the formation of the LPS receptor complex by LPS, LPS-binding protein (LBP),

31 TLR4.myeloid differentiation factor 2 (MD-2) LPS receptor complex is strongly activated by hexa-acyla

32 t that a signal transduction molecule in the LPS receptor complex may belong to the IL-1 receptor/tol

33 ding the function and biology of the corneal LPS receptor complex may lead to novel therapies for the

34 lls are capable of expressing the functional LPS receptor complex proteins, CD14 and Toll-like recept

35 The LPS receptor complex utilized by the bladder epithelial

36 ctions as the transmembrane component of the LPS receptor complex, an unduplicated pathway for the de

37 binding protein membrane CD14 to serve as an LPS receptor complex, and that LPS treatment enhances th

38 luable tools to characterize elements in the LPS receptor complex, as well as to activate or inhibit

39 ith decreased cell surface expression of the LPS receptor complex, Toll-like receptor 4 (TLR4)/MD-2.

40 omponents at the cell surface as part of the LPS receptor complex.

41 tly to each of the members of the tripartite LPS receptor complex.

42 lore its LPS binding ability and role in the LPS receptor complex.

43 e central lipid A-recognition protein in the LPS receptor complex.

44 vidual components of the lipopolysaccharide (LPS) receptor complex of proteins remain unclear.

45 uggests that the functional integrity of the LPS receptor depends both on the surface expression of a

46 Analysis of LPS receptor expression in AnxA1-null macrophages indica

47 e deletions essentially ablated soluble CD14 LPS receptor function, whereas only two of the deletions

48 deletions completely destroyed membrane CD14 LPS receptor function.

49 4 have different structural determinants for LPS receptor function.

50 imeric, truncated CD14 is a fully functional LPS receptor in both cell lines.

51 To determine the role of the CD14 LPS receptor in the pathogenic effects of naturally occu

52 ignaling molecules potentially downstream of LPS receptors in activated macrophages.

53 (TLR4) is an important lipo-polysaccharide (LPS) receptor in gastric epithelial cell signaling trans

54 receptor 4 (Tlr4) is the lipopolysaccharide (LPS) receptor in mice was reported.

55 The major monocyte/macrophage LPS receptor is the glycosylphosphatidylinositol (GPI)-a

56 The lipopolysaccharide (LPS) receptor is a multi-protein complex that consists o

57 e receptor 4 (Tlr4), the lipopolysaccharide (LPS) receptor, is sufficient to induce nuclear factor ka

58 either lacking or expressing human CD14 (the LPS receptor), it was observed that expression of human

59 binding to the O-antigen lipopolysaccharide (LPS) receptor of Salmonella were examined at high temper

60 gest that moesin functions as an independent LPS receptor on human monocytes.

61 l half of the membrane CD14 was a functional LPS receptor on the cell membrane, we engineered a chime

62 een LPS responsiveness and the expression of LPS receptors or factors regulating LPS responsiveness o

63 colitis and in humans certain alleles of the LPS receptor protein TLR4 increase inflammatory bowel di

64 he cornea expresses functional CD14 and TLR4 LPS receptor proteins.

65 Our data, showing that LPS receptor signaling and neutralization of endogenous

66 Platelets express components of the LPS receptor-signaling complex, including TLR (TLR4), CD

67 al epithelial cells expressed the functional LPS receptor-signaling protein TLR4, which was also augm

68 study, we investigated the importance of the LPS receptor TLR4 and MyD88, an adaptor molecule involve

69 of VEGF, NRP-1 directly interacted with the LPS receptor TLR4 and suppressed downstream signaling th

70 argeting of multiple elements, including the LPS receptor TLR4 and the key adaptor/signaling proteins

71 ry cytokines, along with upregulation of the LPS receptor TLR4 in lung tissue and increased activatio

72 velopment in mice requires activation of the LPS receptor TLR4 on the intestinal epithelium, through

73 These data indicate that the LPS receptor TLR4, as well as TLR2 and CD14, do not play

74 endent IFN-beta production downstream of the LPS receptor TLR4.

75 t mice, we demonstrated that the presence of LPS receptor (TLR4) is not required on hematogenous immu

76 We hypothesized that the LPS receptor (TLR4) plays a critical role in NEC develop

77 ve demonstrated that the lipopolysaccharide (LPS) receptor (TLR4) is expressed in TRPV1 containing tr

78 culture, we demonstrate that hRetn binds the LPS receptor Toll-like receptor 4 (TLR4) through its N t

79 LPS activate caspase-11 independently of the LPS receptor Toll-like receptor 4 (TLR4).

80 at regulates signals transduced by the major LPS receptor Toll-like receptor 4 on the surface of mous

81 LPS without affecting the expression of the LPS receptor Toll-like receptor 4, demonstrating that RI

82 which acute lung inflammation depends on the LPS receptor (Toll-like receptor 4, TLR-4), the loss of

83 C3HHeJ, which has a mutation in the primary LPS receptor, Toll-like receptor 4 (TLR4), is extremely

84 charide (LPS) requires signaling through the LPS receptor, Toll-like receptor 4 (TLR4).

85 Endotoxin-mediated down-regulation of the LPS receptor, Toll-like receptor 4, has been suggested a

86 The putative LPS receptor, Toll-like receptor 4, was expressed in THP

87 way of signaling pathways downstream of the LPS receptor, Toll-Like Receptor 4.

88 e effects were identical regardless of which LPS receptor was expressed.

89 cteria) binds to CD14 (a lipopolysaccharide (LPS) receptor) was tested.

90 s effect, the expression of CD14, the formal LPS receptor, was analyzed.

91 is the signal transduction component of the LPS receptor, whereas MD-2 is the endotoxin-binding unit