ライフサイエンスコーパス: LPS-binding protein

1 aflet of apoptotic cell membranes, and CD14 (LPS-binding protein).

2 ein and accessory proteins, such as CD14 and LPS binding protein.

3 s inhibited by anti-CD14 mAb and enhanced by LPS binding protein.

4 des directly inhibited the binding of LPS to LPS-binding protein.

5 anced by the addition of soluble CD14 and/or LPS-binding protein.

6 ses to LPS, and not to PGN, were enhanced by LPS-binding protein.

7 dependent and was not augmented by exogenous LPS-binding protein.

8 4-70Z/3 cells by H. pylori LPS also requires LPS-binding protein.

9 quires the presence of plasma containing the LPS-binding protein.

10 he 20S proteasome complex were identified as LPS-binding proteins.

11 opology of the "active-site" beta-strands of LPS-binding proteins.

12 LPS-binding protein, a lipid transfer protein found in s

13 nitially bound by transfer proteins, notably LPS binding protein and phospholipid transfer protein, a

14 by competing with E. coli LPS for binding to LPS-binding protein and by directly competing with E. co

15 man SR-BI orthologue, was determined to be a LPS-binding protein and endocytic receptor mediating the

16 and LPS-triggered responses were enhanced by LPS-binding protein and inhibited by an anti-CD14 monocl

17 tivated by LPS in a response that depends on LPS-binding protein and is enhanced by CD14.

18 These data indicate that MD-2 is a genuine LPS-binding protein and strongly suggest that MD-2 could

19 cells to LPS require a plasma protein called LPS-binding protein and the glycosylphosphatidylinositol

20 The structure reveals homology to eukaryotic LPS-binding proteins and allowed for the prediction of a

21 homologous to the LPS binding region of the LPS binding protein, and we demonstrated that two basic

22 no acid conservation, structural analysis of LPS-binding proteins, and MD simulations further confirm

23 d formed monomeric complexes with MD-2 in an LPS-binding protein- and CD14-dependent manner with simi

24 /CD18-transfected CHO-K1, thus implying that LPS-binding protein can also transfer LPS to CD11/CD18.

25 100A8; the acute-phase protein SAA3; and the LPS binding protein CD14 were confirmed by Northern blot

26 rotein and protein-protein interactions with LPS-binding protein, CD14, myeloid differentiation prote

27 assay, suggest that recombinant factor C, an LPS binding protein, competitively inhibits high-density

28 Both forms of C1INH blocked the LPS-binding protein-dependent binding of Salmonella typh

29 icking the putative LPS-binding sites of the LPS-binding protein family.

30 induction of APP, including serum amyloid A, LPS-binding protein, fibrinogen, or ceruloplasmin; in co

31 es demonstrated that these surface expressed LPS-binding proteins had characteristics that were quali

32 lease from the cells, high concentrations of LPS-binding protein have a modest effect, and phospholip

33 easing protein (BPI) and lipopolysaccharide (LPS)-binding protein, have been considered to be members

34 n for the complex of bacterial LPS (LPS) and LPS binding protein in animals.

35 Several LPS binding proteins in HCEP were identified by an overl

36 This study addresses the role of CD14 and LPS-binding protein in the cellular response to H. pylor

37 This cross-linker was used to identify the LPS-binding proteins in membranes of the murine-macropha

38 d by the IL-1R system and was independent of LPS-binding proteins in serum.

39 The closely related LPS-binding protein, in contrast to BPI, did not increas

40 s of microbial translocation, as measured by LPS-binding protein, in PTM correlated with the rate of

41 receptor molecules in HCEP, that one of the LPS binding proteins is galectin-3, and that the outer c

42 that TECs express CD14, a well-characterized LPS-binding protein known to mediate many LPS responses.

43 MD-2 binding to LPS did not require LPS-binding proteins LBP and CD14; in fact LBP competed

44 Binding of LPS-LPS binding protein (LBP) complexes to CD14, a surface r

45 LPS forms a complex with the LPS binding protein (LBP) in plasma, and LPS-LBP complex

46 These were identified as apoA-I, LPS binding protein (LBP), and factor H-related proteins

47 complex requires the coordinated function of LPS binding protein (LBP), CD14, MD-2, and TLR4.

48 In the presence of LPS binding protein (LBP), large LPS aggregates were int

49 In conjunction with a serum protein, LPS binding protein (LBP), LPS-CD14 interactions mediate

50 d plasma levels of lipopolysaccharide (LPS), LPS binding protein (LBP), soluble CD14 (sCD14), and int

51 LPS binding protein (LBP), which is present in normal se

52 effective LPS uptake only in the presence of LPS binding protein (LBP).

53 ges in the absence of the accessory molecule LPS binding protein (LBP).

54 Lipopolysaccharide (LPS) binding protein (LBP) is a key serum factor that me

55 Lipopolysaccharide (LPS) binding protein (LBP) is a lipid transfer protein t

56 Lipopolysaccharide (LPS)-binding protein (LBP) and bactericidal/permeability

57 Lipopolysaccharide (LPS)-binding protein (LBP) is an acute phase reactant th

58 o closely related endogenous serum proteins, LPS-binding protein (LBP) and bactericidal/permeability-

59 We have investigated the effects of human LPS-binding protein (LBP) and human bactericidal/permeab

60 in, we found that two human plasma proteins, LPS-binding protein (LBP) and phospholipid transfer prot

61 popolysaccharide (LPS)-interactive proteins, LPS-binding protein (LBP) and the bacteridical/permeabil

62 Polymorphonuclear leukocytes (PMN) and LPS-binding protein (LBP) are both components of the inn

63 LPS-binding protein (LBP) catalyzes the movement of LPS

64 Serum endotoxin and LPS-binding protein (LBP) concentrations were determined

65 LPS-binding protein (LBP) increased the binding of sCD14

66 sm(s) remains to be fully defined, the human LPS-binding protein (LBP) is known to regulate responses

67 LPS-binding protein (LBP) plays an important role in aug

68 lycosylphosphatidylinositol-anchored form of LPS-binding protein (LBP), a component of serum that bin

69 Gelsolin also competes with LPS-binding protein (LBP), a high-affinity carrier for L

70 onses to LPS are markedly potentiated by the LPS-binding protein (LBP), a lipid-transfer protein that

71 cytokines as well as components of the LPS, LPS-binding protein (LBP), and CD14 system in bronchoalv

72 plex consisting of lipopolysaccharide (LPS), LPS-binding protein (LBP), and the cell surface antigen

73 , TLR4, and MD-2, which, in conjunction with LPS-binding protein (LBP), bind LPS to the virus and aug

74 ormation of the LPS receptor complex by LPS, LPS-binding protein (LBP), CD14, and toll-like receptor

75 by two closely related LPS-binding proteins, LPS-binding protein (LBP), which potentiates LPS' inflam

76 not bind host LPS-sensing molecules such as LPS-binding protein (LBP).

77 onses to endotoxins are enhanced markedly by LPS-binding protein (LBP).

78 ed as the receptor for complexes of LPS with LPS-binding protein (LBP).

79 for lipopolysaccharide (LPS) complexes with LPS-binding protein (LBP).

80 first incubated with both LPS and the serum LPS-binding protein (LBP).

81 und CD14 (mCD14) and a plasma protein called LPS-binding protein (LBP).

82 mbinant sCD14 and human serum or recombinant LPS-binding protein (LBP).

83 PS)) can be regulated by two closely related LPS-binding proteins, LPS-binding protein (LBP), which p

84 that TLR2 associates with the high-affinity LPS binding protein membrane CD14 to serve as an LPS rec

85 n a CD14-dependent manner, and soluble CD14, LPS binding protein, or their combination potentiated bo

86 Next, LPS binding protein, phospholipid transfer protein, and

87 contrast, the addition of recombinant human LPS-binding protein (rLBP) had opposing effects on the L

88 els of circulating lipopolysaccharide (LPS), LPS-binding protein, soluble CD14, and fucose-binding le

89 n-induced cytokine production was maximal at LPS-binding protein:soluble CD14 ratios <1, typically ob

90 dividuals with subclinical infection; higher LPS-binding protein:soluble CD14 ratios were inhibitory.

91 ons, in a defined medium containing purified LPS-binding protein, the LPS-deacylating activity of MNC

92 form complexes with a serum protein known as LPS-binding protein; the LPS in this complex is subseque

93 we show that LPS in the presence of serum or LPS binding protein triggers formation of CD14-CR3 compl

94 LPS binding protein was not required for OspA-induced cy

95 Serum proteins, including CD14 and LPS-binding protein, were identified as key targets for

96 LPS-binding protein, which transfers LPS to CD14, enhanc

97 increasing protein (BPI) are closely related LPS-binding proteins whose binding to LPS has markedly d

98 iginally identified as a lipopolysaccharide (LPS) binding protein with gram-negative bactericidal act