ライフサイエンスコーパス: M. pulmonis

1 lung disease developed after infection with M. pulmonis.

2 amide (CYP) and inoculated with 10(7) CFU of M. pulmonis.

3 e could demonstrate that it was expressed in M. pulmonis.

4 ious Bcg and H-2 genotypes for resistance to M. pulmonis.

5 hmatic airways to facilitate colonization by M. pulmonis and the capacity of M. pulmonis to exacerbat

6 erior to single PCR or culture for detecting M. pulmonis, and that M. pulmonis is present in all but

7 Both Tn4001C and Tn4001T transposed in M. pulmonis, and Tn4001T transposed in M. arthritidis.

8 Rats were inoculated with 3 X 10(7) CFU of M. pulmonis at 10 days prior to breeding (-10) or at ges

9 model clearly provides a mechanism by which M. pulmonis can alter its surface architecture and also

10 Populations of M. pulmonis cells that arose during growth in different

11 The M. pulmonis chromosome has two hsd loci, both of which c

12 not be cultured and identified 2 additional M. pulmonis-contaminated CAR bacillus isolates.

13 of 61 (34%) CAR bacillus samples from which M. pulmonis could not be cultured and identified 2 addit

14 nificant role in determining the severity of M. pulmonis disease.

15 Mice were infected with M. pulmonis for measurements of alveolar fluid clearance

16 tsZ gene was overexpressed, and the purified M. pulmonis FtsZ bound GTP.

17 Expression of the M. pulmonis ftsZ gene in E. coli inhibited cell division

18 The M. pulmonis ftsZ gene was overexpressed, and the purifie

19 We report here that a single recombinase in M. pulmonis, HvsR, catalyses independent DNA inversions

20 Nested PCR also detected M. pulmonis in 14 of 20 (70%) paraffin sections of lung

21 Nested PCR also detected M. pulmonis in 21 of 61 (34%) CAR bacillus samples from

22 licated as a virulence determining factor in M. pulmonis-induced murine respiratory disease, the prec

23 ary clearance and altered airway function in M. pulmonis-infected animals.

24 CYP pretreatment of M. pulmonis-infected iNOS(+/+) and iNOS(-/-) mice reduce

25 e changes in blood vessels and lymphatics in M. pulmonis-infected mice.

26 Ang1 and Ang2 protein increased in M. pulmonis-infected mouse airways but came from differe

27 rce for capillary remodeling into venules in M. pulmonis-infected mouse airways.

28 n of venous markers, and leukocyte influx in M. pulmonis-infected mouse airways.

29 M. pulmonis-infected MTEs, but not those infected with a

30 r, AX102 exaggerated leakage at 7 days after M. pulmonis infection and increased vascular remodeling

31 lymphangiogenesis in inflamed airways after M. pulmonis infection because expression of the integrin

32 clude that the polarized stimulus created by M. pulmonis infection differentially changes the size, s

33 t in mice genetically predisposed to asthma, M. pulmonis infection elicits an inflammatory milieu in

34 a significant impact on lung disease due to M. pulmonis infection in mice.

35 ymphangiogenesis occurs in mouse lungs after M. pulmonis infection through a mechanism involving sign

36 Similar to M. pulmonis infection, systemic overexpression of angiop

37 g and the consequences of inflammation after M. pulmonis infection.

38 A were present in EphA2-deficient mice after M. pulmonis infection.

39 culture for detecting M. pulmonis, and that M. pulmonis is present in all but four CAR bacillus isol

40 infected with 10(10) colony-forming units of M. pulmonis, killed mycoplasmas within 6 h.

41 nduced both humoral and cellular immunity to M. pulmonis, largely prevented infection (vaccination),

42 nst two MnuA peptide sequences identified an M. pulmonis membrane protein of approximately 42 kDa by

43 Further study of the MTE-M. pulmonis model should elucidate the molecular mechani

44 Of 27 samples known to contain M. pulmonis, only 12 (44%) were positive in the first PC

45 anasal infection with 5 x 10(4) CFU virulent M. pulmonis organisms.

46 that when encased within a biofilm, cells of M. pulmonis producing a short form of the Vsa protein we

47 M. pulmonis producing a VsaA protein with about 40 tande

48 Sequencing of the ftsZ homolog from M. pulmonis revealed that it was highly homologous to ot

49 The transfer of anti-M. pulmonis serum to infected C3H-SCID mice prevented ex

50 We isolated and analyzed M. pulmonis strain CT variants (CT182 and derivatives) t

51 s comprising a 10-kb region of the genome of M. pulmonis strain KD735-15.

52 When M. pulmonis strain X1048 was propagated in laboratory cu

53 oculated with an avirulent, poorly infective M. pulmonis strain, 14 (19%) were positive by nested PCR

54 M. pulmonis strains that produce VsaA with about 40 tand

55 Isolation and analysis of M. pulmonis strains that produced Vsa proteins other tha

56 In contrast, the M. pulmonis strains that produced VsaA R40 were highly r

57 ate the Vsa proteins nonspecifically mediate M. pulmonis surface interactions and function to sterica

58 To examine vsa genes in a strain of M. pulmonis that is unrelated to KD735-15, strain CT was

59 fected by the bacterium Mycoplasma pulmonis (M. pulmonis), the segment of the microvasculature that s

60 Furthermore, the ability of M. pulmonis to alter transport without killing the host

61 onization by M. pulmonis and the capacity of M. pulmonis to exacerbate symptoms associated with acute

62 ough release of IFN-gamma and the ability of M. pulmonis to trigger the production of Th2-type cytoki

63 re inoculated intranasally with 10(4) CFU of M. pulmonis UAB CT and evaluated at 21 days postinfectio

64 nd characterized genes encoding V-1 from two M. pulmonis UAB CT V-1 variants that differ in hemadsorp

65 were infected intranasally with 10(5) CFU of M. pulmonis UAB CT, and their lungs were quantitatively

66 To determine the direct effect of M. pulmonis upon transepithelial ion transport in the ab

67 Furthermore, M. pulmonis Vsa variants were susceptible to the polypep

68 M. pulmonis was isolated from the placenta, amniotic flu

69 Altered transport due to M. pulmonis was not merely a result of epithelial cell d

70 The dispensable and essential genes of M. pulmonis were compared with those reported for Mycopl

71 with CAR bacillus isolates known to contain M. pulmonis, whereas single PCR gave no positive results

72 In the absence of AMs, incubation of M. pulmonis with the peroxynitrite generator 3-morpholin