ライフサイエンスコーパス: MALDI

1 MALDI analysis supports the simultaneous formation of ol

2 MALDI IMS was used to visualize the distribution of anti

3 MALDI MSI of the hippocampal area allowed targeted fatty

4 MALDI-MS data revealed several fucosylated tri- and tetr

5 MALDI-MS identified proteolytic fragments from ovalbumin

6 MALDI-MSI identified endogenous molecular markers that i

7 MALDI-TOF mass spectrometry indicates that hydrogen pero

8 MALDI-TOF MS analysis of the suspension after density-ba

9 MALDI-TOF MS has the potential to expedite mold identifi

10 MALDI-TOF MS plus AMS intervention significantly reduced

11 MALDI-TOF MS significantly improved TAT for organism ID.

12 MALDI-TOF MS was effective for the identification of myc

13 MALDI-TOF score value identification identified correctl

14 MALDI-TOF was found as a useful and quick technique to o

15 MALDI-TOF-MS shows excellent potential for sensitive and

16 iable relative quantification in 2D- and 3D- MALDI MSI data sets.

17 A MALDI-MSI scan performed at the equivalent density of 49

18 ptide fragment was detected at m/z 1088 by a MALDI-TOF mass spectrometry.

19 ctly detected in the inhibitory zone using a MALDI-imaging mass spectrometry, and the purified compou

20 In this study, we attempted to validate a MALDI-ToF mass spectrometry-based assay for the antifung

21 most commonly used illicit drug worldwide, a MALDI-MS method for the detection and mapping of cannabi

22 Additionally, MALDI-IMS is able to detect three metabolites of doxorub

23 Additionally, MALDI-ToF-MS indicates the polymerization of glyoxal/gly

24 After MALDI MS analysis, a majority of the analyte remains for

25 ictive value (NPV) of MALDI-TOF MS alone and MALDI-TOF MS coupled with UA were 86.6% versus 93.4% (ch

26 , high resolution mass by Q-ToF analysis and MALDI-MS allowed identification of compounds, such as p-

27 olated nucleoplasts and Western blotting and MALDI-TOF of nuclear extracts show that Avp triggers Avp

28 We applied microchip electrophoresis and MALDI-TOF-MS-based glycomic procedures to 20 control ser

29 nd direct correlation of electrophoretic and MALDI-MS results.

30 tary techniques, such as FTIR, NMR, EPR, and MALDI-ToF, were employed.

31 R and detection by single-base extension and MALDI-TOF mass spectrometry, in a novel method to assess

32 lowing standardized culture, extraction, and MALDI-TOF MS analysis, isolates were identified using sc

33 fragments in bulk by SDS-PAGE, RP-HPLC, and MALDI-TOF proves that the previous pepsin exposition pro

34 entified as DHRS9 by immunoprecipitation and MALDI-MS sequencing.

35 he sample surface with the heating laser and MALDI-MS imaging to map the resulting products.

36 Chemical cross-linking and MALDI-TOF MS mapped these same regions to the PhuS:HemO

37 the first time, the use of ESI-FTICR MS and MALDI-FTICR MS is described in a complementary manner wi

38 using saturation transfer difference-NMR and MALDI-TOF.

39 ermore, we applied interference peptides and MALDI-TOF mass spectrometry to confirm APJ homo-dimer an

40 ated protein in A3HtrAOE with a mass, pI and MALDI-TOF spectrum consistent with outer membrane protei

41 entification (CONV), (ii) manual plating and MALDI-TOF MS identification (MALDI), (iii) MALDI-TOF MS

42 However, current sample preparation and MALDI-IMS acquisition methods have limitations in preser

43 36 degrees C using a spectrophotometer) and MALDI-TOF MS (both the standard result output and by vis

44 surface was preserved and imaged by SPR and MALDI MS.

45 dy assesses a novel bile solubility test and MALDI-TOF for the differentiation of Streptococcus pneum

46 nsitivity and that the combination of UA and MALDI-TOF MS provided an accurate and rapid detection an

47 In our approach, MALDI is performed in the elevated pressure regime (5-8

48 important factors that must be considered as MALDI-TOF MS moves into applications beyond microbial id

49 to deposit a custom-prepared ink with DHB as MALDI matrix, a primary lipids-based internal standard,

50 ve and durable enough to be used directly as MALDI plates.

51 pectroscopy is a rapid technique, as fast as MALDI-TOF, and has been shown to accurately identify bac

52 olved in mass spectrometry analysis, such as MALDI matrix, plate, and sample preparation, were also i

53 f signaling pathway members using a benchtop MALDI mass spectrometer within approximately 6-7 h.

54 he imaging protocol developed here with both MALDI and SALDI provides the best and most diverse lipid

55 These fragments can then be analyzed by MALDI mass spectrometry, and the peptide sequences read

56 osa, and E nterobacter spp. were analyzed by MALDI-TOF-MS in negative ion mode to obtain glycolipid m

57 SA and high spatial resolution attainable by MALDI.

58 esulting bioconjugates were characterized by MALDI-TOF MS, differential scanning calorimetry (DSC), f

59 s with their molecular weights determined by MALDI-MS, and (iii) electrophoretic profiles of N-glycan

60 te knowledge in the analysis of this drug by MALDI-MS.

61 obtained using protein profiles generated by MALDI-FTICR MS.

62 esis, SDS-PAGE and protein identification by MALDI-TOF MS.

63 ibility testing of the samples identified by MALDI-TOF MS produced an overall categorical agreement o

64 te ionizable complexes that can be imaged by MALDI MSI.

65 ted pimonidazole metabolite can be imaged by MALDI-MSI in a breast tumor xenograft model.

66 d 21 VISA, 21 hVISA, and 38 VSSA isolates by MALDI-TOF MS.

67 nd permethylated, N-glycans were measured by MALDI mass spectrometry.

68 individual markers identified previously by MALDI-FTICR MSI.

69 These findings were supported by MALDI imaging, showing NEP mediated Ang-(1-7) formation

70 of the detected peaks remained unresolved by MALDI-TOF, which led to a 3-5 times lower number of m/z

71 cy of the substitution has been validated by MALDI-TOF MS analysis of the functionalized precursors a

72 f malvidin-3,5-O-diglycoside was verified by MALDI-TOF MS.

73 bly because of ejection of a particular cold MALDI plume.

74 In this work, we report on a novel combined MALDI/ESI interface, which was coupled to different Orbi

75 Here we report combined MALDI-TOF MS experiments, NMR analyses and quantum mecha

76 Combining MALDI and NMR techniques further enables us to extract e

77 This work focuses on comparing MALDI results to those of our previous electrospray ioni

78 This gentle, histology-compatible MALDI-IMS protocol also diminished thermal effects and m

79 In conclusion MALDI-MSI described specific lipid profiles that could b

80 hanced signals when compared to conventional MALDI, with higher m/z analytes being enhanced to the gr

81 However, coupling MALDI with HDX has been challenging because of undesired

82 We applied this newly developed MALDI-HDX workflow to study the effect of several common

83 The commercial in vitro diagnostic MALDI Sepsityper (Sepsityper) kit has the potential for

84 oxia, it is likely that the presented direct MALDI-MSI approach is also applicable to other tissues f

85 improved spot quality enables 2-30x enhanced MALDI-MS signals along with substantial reductions of th

86 laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry for the detection of organi

87 laser desorption ionization-time of flight (MALDI-TOF) mass spectrometry might allow the accurate id

88 laser desorption/ionization-time of flight (MALDI-TOF) mass spectrometry revealed identical SIFamide

89 laser desorption/ionization time of flight (MALDI-TOF) mass spectrometry.

90 laser desorption ionization-time of flight (MALDI-TOF) methodology, suggesting that MALDI-TOF can of

91 laser desorption ionization-time of flight (MALDI-TOF) MS organism identification and automated-syst

92 laser desorption/ionization time-of-flight (MALDI TOF) approaches have historically suffered from po

93 laser desorption ionization time-of-flight (MALDI-TOF) mass spectrometric detection-are attractive a

94 laser desorption-ionization time-of-flight (MALDI-TOF) mass spectrometry (MS).

95 ix-assisted laser desorption time-of-flight (MALDI-ToF) mass spectrometry further identified specific

96 laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry.

97 laser desorption/ionization time-of-flight (MALDI-TOF) mass spectrometry.

98 Laser Desorption/Ionization Time-of-Flight (MALDI-TOF) technique for bacterial identification after

99 s on-chip, including the matrix delivery for MALDI-TOF analysis.

100 A nonaqueous matrix was proposed for MALDI sample preparation to minimize undesirable back-ex

101 which have m/z values that are distinct from MALDI matrix-related ions.

102 produced smaller peptides, as evidenced from MALDI-TOF spectrometry.

103 e, thus categorizing the lipidome for future MALDI-MSI studies of pulmonary diseases.

104 ssful interface of optical microscopy-guided MALDI MS and CE-ESI-MS for sequential chemical profiling

105 Optically guided MALDI MS provides a high-throughput assessment of lipid

106 were rapidly analyzed with optically guided MALDI MS to classify each cell into established cell typ

107 Optically guided MALDI MS was used to identify individual pancreatic isle

108 ual plating and MALDI-TOF MS identification (MALDI), (iii) MALDI-TOF MS identification and early phas

109 d MALDI-TOF MS identification (MALDI), (iii) MALDI-TOF MS identification and early phase implementati

110 ption/ionization mass spectrometric imaging (MALDI-MSI) of agarose micro-beads randomly arrayed at hi

111 rption ionization mass spectrometry imaging (MALDI-MSI) and complemented by quantitative measurement

112 rption ionization mass spectrometry imaging (MALDI-MSI) generally involves embedding the tissue follo

113 rption ionization mass spectrometry imaging (MALDI-MSI) in order to characterize the lipid profiles a

114 rption ionization-mass spectrometry imaging (MALDI-MSI) is a technique that allows the mapping of met

115 rption/ionization mass spectrometry imaging (MALDI-MSI), which has been previously used to directly m

116 rption/ionization-mass spectrometry imaging (MALDI-MSI).

117 ally relevant Nocardia spp. and to implement MALDI-TOF MS libraries developed by single laboratories

118 Implementing MALDI-TOF plus stewardship review and intervention decre

119 Despite the additional costs of implementing MALDI-TOF and of dedicating pharmacy stewardship personn

120 rrelated images were acquired in SPRi and in MALDI IMS for abundant proteins from a single mouse kidn

121 enerated characteristic isotopic patterns in MALDI-TOF MS, and both a fragmentation product y1 ion co

122 ilar ionisation properties and resolution in MALDI-TOF-MS, these phosphopeptides were identified as s

123 The quest for internal standards useful in MALDI imaging studies goes on to get not only lateral di

124 [M + H](+) (199 Da) parent ions, whereas in MALDI each isomer shows significant formation of three p

125 matrix-assisted laser desorption ionization (MALDI) and surface-assisted laser desorption ionization

126 matrix-assisted laser desorption ionization (MALDI) has recently advanced to allow for the visualizat

127 Matrix-assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS) of muscle and abd

128 matrix assisted laser desorption ionization (MALDI) imaging mass spectrometry (IMS), we determined al

129 matrix-assisted laser desorption ionization (MALDI) mass spectrometry-based reference results.

130 matrix-assisted laser desorption ionization (MALDI), electrospray ionization (ESI), tandem mass spect

131 matrix-assisted laser desorption ionization (MALDI), typically requiring derivatization steps to over

132 matrix-assisted laser desorption/ionization (MALDI) as a new matrix for mass spectrometry imaging (MS

133 Matrix-assisted laser desorption/ionization (MALDI) coupled with a time-of-flight (TOF) mass-spectrom

134 Matrix-assisted laser desorption/ionization (MALDI) imaging mass spectrometry (IMS) elucidates molecu

135 matrix-assisted laser desorption/ionization (MALDI) imaging, we determined that the drug penetrates t

136 matrix-assisted laser desorption/ionization (MALDI) IMS experiments.

137 matrix-assisted laser desorption/ionization (MALDI) mass spectrometry (MS) successfully tracks the ev

138 Matrix-assisted laser desorption/ionization (MALDI) mass spectrometry imaging (MSI) is used for the m

139 matrix-assisted laser desorption/ionization (MALDI) method.

140 Matrix-assisted laser desorption/ionization (MALDI) MS and capillary electrophoresis electrospray ion

141 matrix-assisted laser desorption/ionization (MALDI) MSI.

142 matrix assisted laser desorption/ionization (MALDI), while producing higher quality spectra.

143 matrix-assisted laser desorption/ionization (MALDI)-mass spectrometry imaging (MSI) to map and visual

144 matrix assisted laser desorption/ionization (MALDI)-MSI and liquid extraction surface analysis (LESA)

145 matrix-assisted laser desorption/ionization (MALDI-)MS were used to image and quantify the uptake of

146 matrix assisted laser desorption/ionization (MALDI-TOF) mass spectrometry (MS).

147 matrix-assisted laser desorption/ionization (MALDI-TOF-MS) for determination of Cu, Fe, Mn and Zn and

148 Matrix-Assisted Laser Desorption Ionization, MALDI, has been increasingly used in a variety of biomed

149 phase implementation of TLA (TLA1), and (iv) MALDI-TOF MS identification and late phase implementatio

150 served when compared to matrix-assisted LDI (MALDI) methods using 2,5-dihydrobenzoic acid as matrix.

151 The compounds ionized by LDI/MALDI belong to low oxygen classes (maximum number of sp

152 of this volume onto a chip with micropillar MALDI targets.

153 -donors, crown ethers and related molecules, MALDI matrix molecules), pi-ligands (alkenes, alkynes, b

154 fore, a multi-modal molecular imaging (MRI & MALDI IMS) approach was employed to examine the temporal

155 utility of the Bruker Biotyper and Vitek MS MALDI-TOF MS systems and their in vitro diagnostic (IVD)

156 (2) UVB and 1.2 x 10(5) J/m(2) UVA), neither MALDI-TOF-MS nor RT-qPCR detected significant decreases

157 Nevertheless, MALDI-TOF allowed reproducing and verifying individual m

158 required, demonstrate the value of this new MALDI-TOF MS method as an analytical tool for the identi

159 other characterization techniques ((1)H NMR, MALDI-HRMS, and size-exclusion chromatography).

160 Nocardia isolates, and NIH and OSU Nocardia MALDI-TOF MS libraries were distributed to three centers

161 tions in the databases and in the ability of MALDI-TOF MS to rapidly identify slowly growing mycobact

162 Application of MALDI-MS, ESI-MS, and IM-MS to the polymer-peptide bioma

163 detect many low-mass metabolites because of MALDI matrix interferences.

164 alyses demonstrate the technical capacity of MALDI-IMS for comprehensive identification of peptidomic

165 In this study, we employed a combination of MALDI imaging mass spectrometry (MALDI-IMS) and MS/MS mo

166 and evaluated the capacity of combination of MALDI-TOF MS and urine analysis (UA) for direct detectio

167 investigated the histology compatibility of MALDI-IMS to image neuronal lipids in rodent brain tissu

168 y, resulting in interfered correspondence of MALDI-IMS data with subsequently acquired immunofluoresc

169 ting system and included additional costs of MALDI-TOF equipment, supplies and personnel, and dedicat

170 of this study was to evaluate the impact of MALDI-TOF MS alone versus MALDI-TOF MS combined with rea

171 th blocks before and after implementation of MALDI-TOF plus stewardship intervention.

172 he three sites, while specificity and NPV of MALDI-TOF MS for males were significantly higher than th

173 PPV), and negative predictive value (NPV) of MALDI-TOF MS alone and MALDI-TOF MS coupled with UA were

174 This study demonstrates the power of MALDI-MSI to reveal unprecedented insights on metabolic

175 In this work, we report the specificity of MALDI-TOF MS for the identification of 162 Mycobacterium

176 Use of MALDI-TOF MS and TLA individually and together results i

177 This review discusses the various uses of MALDI-TOF MS for the identification and susceptibility t

178 s than 5 h and automated data acquisition on MALDI-TOF-MS took on average less than 1 min per sample.

179 by regular electrospray ionization (ESI) or MALDI.

180 le for at least 24 h under the vacuum of our MALDI mass spectrometer.

181 owed the usefulness for fast in situ peptide MALDI sequencing; the lectin-based protein chips showed

182 using computer simulation and by performing MALDI-MS analysis directly from the open microchannel.

183 The proposed MALDI-HDX approach can also be applied in a high-through

184 ic ((1)H NMR and DI-LC-MS/MS) and proteomic (MALDI-TOF/TOF-MS) platforms.

185 Following UV254 exposure, quantitative MALDI-TOF-MS detected significantly more RNA modificatio

186 f each species were used to create reference MALDI-TOF spectra, which were then used for the identifi

187 de were profiled in a single high resolution MALDI-FTICR spectrum.

188 as exemplified by performing high-resolution MALDI-IMS with subsequent fluorescent amyloid staining i

189 pplied 5- and 10 mum high spatial resolution MALDI-MSI to the asymmetric Kranz anatomy of Zea mays (m

190 Ultrahigh resolution MALDI-FTICR MS allows the measurement of small proteins

191 n Fourier transform ion cyclotron resonance (MALDI-FTICR) mass spectrometry (MS).

192 By the comparison II results, MALDI significantly improved TAT to organism ID compared

193 s from the serum followed by highly specific MALDI detection.

194 m-ion cyclotron resonance mass spectrometry (MALDI-FT-ICR MS) and single cell imaging flow cytometry

195 bination of MALDI imaging mass spectrometry (MALDI-IMS) and MS/MS molecular networking to study chemi

196 rption/ionization imaging mass spectrometry (MALDI-IMS) enables acquisition of spatial distribution m

197 rption/Ionization-Imaging Mass Spectrometry (MALDI-IMS) with confirmation by steady state fluorescenc

198 ser desorption ionization-mass spectrometry (MALDI-MS) except the phospholipids where laser desorptio

199 ser desorption ionization mass spectrometry (MALDI-MS) profiling and imaging for the detection and ma

200 ser desorption/ionization-mass spectrometry (MALDI-MS), a common technique used for characterizing sy

201 ser desorption/ionization mass spectrometry (MALDI-MS).

202 ser desorption/ionization mass spectrometry (MALDI-MS).

203 ser desorption/ionization-mass spectrometry (MALDI-MS).

204 ser desorption ionization mass spectrometry (MALDI-MS).

205 ionization-time-of-flight mass spectrometry (MALDI-TOF MS) after enzymatic digestion of the polysacch

206 ionization-time of flight mass spectrometry (MALDI-TOF MS) and BD Kiestra total laboratory automation

207 ionization-time of flight mass spectrometry (MALDI-TOF MS) and evaluated the capacity of combination

208 ionization-time of flight mass spectrometry (MALDI-TOF MS) decreases the time to organism identificat

209 nisation - time-of-flight mass spectrometry (MALDI-TOF MS) fingerprinting of proteins was developed.

210 ionization-time of flight mass spectrometry (MALDI-TOF MS) for rapid organism identification and dedi

211 ionization time of flight mass spectrometry (MALDI-TOF MS) for the identification of Exophiala specie

212 ionization-time of flight mass spectrometry (MALDI-TOF MS) for the identification of NTM isolated on

213 ionization-time of flight mass spectrometry (MALDI-TOF MS) has become the standard for routine bacter

214 ionization-time of flight mass spectrometry (MALDI-TOF MS) has emerged as a rapid and accurate method

215 ionization-time of flight mass spectrometry (MALDI-TOF MS) has reduced the time to identification of

216 ionization-time of flight mass spectrometry (MALDI-TOF MS) has revolutionized clinical microbiology f

217 ionization-time of flight mass spectrometry (MALDI-TOF MS) in conjunction with active antimicrobial s

218 ionization time-of-flight mass spectrometry (MALDI-TOF MS) platforms in the medical microbiological p

219 ionization-time of flight mass spectrometry (MALDI-TOF MS) sample preparation methods, including the

220 ser desorption/ionization mass spectrometry (MALDI-TOF MS) that allows quantification of pure or mixe

221 ionization-time of flight mass spectrometry (MALDI-TOF MS) to detect pKpQIL_p019 (p019)-an approximat

222 ionization-time of flight mass spectrometry (MALDI-TOF MS), suspicious isolates are now routinely ide

223 ionization-time of flight mass spectrometry (MALDI-TOF MS)-based identifications of the flown and sta

224 ionization-time of flight mass spectrometry (MALDI-TOF MS).

225 ionization-time of flight mass spectrometry (MALDI-TOF MS).

226 ion time-of-flight tandem mass spectrometry (MALDI-TOF MS/MS), we now reveal that actually up to five

227 ionisation time-of-flight mass spectrometry (MALDI-TOF) and the determination of their amino acid seq

228 ionization time-of-flight mass spectrometry (MALDI-TOF-MS) analysis of high abundance proteins is gai

229 ionization-time-of-flight-mass spectrometry (MALDI-TOF-MS) is presented.

230 zation - time of flight - mass spectrometry (MALDI-TOF-MS).

231 urified and identified by mass spectrometry (MALDI-TOF/MS).

232 and identified by tandem mass spectrometry (MALDI-TOF/TOF).

233 -of-flight/time-of-flight mass spectrometry (MALDI-TOF/TOF-MS) for sequential identification of the p

234 tions which differ notably from the standard MALDI laser wavelengths of 337, 349, and 355 nm, respect

235 ptides from complex mixtures with subsequent MALDI analysis, and the protein chips with immobilized a

236 In summary, MALDI-TOF MS allows the rapid and accurate identificatio

237 time AMS intervention is more impactful than MALDI-TOF MS alone.

238 ased dynamic range and higher precision than MALDI-TOF MS, while still generating results in a simila

239 Here, we demonstrate that MALDI-TOF mass spectrometry accurately identified all of

240 It was found that MALDI MS images could be used to visualize regions sampl

241 Our work shows that MALDI-TOF mass spectrometry is suitable for quantitative

242 ght (MALDI-TOF) methodology, suggesting that MALDI-TOF can offer rapid, reliable identification in li

243 The MALDI polysaccharide profiles of 5 supplements from diff

244 The MALDI-TOF spectrum showed the presence of pseudo-protein

245 or variability in sample preparation and the MALDI process itself.

246 Combining the bile solubility test and the MALDI-TOF spectra results provide a correct identificati

247 has revealed excellent agreement between the MALDI and histological images.

248 f other aerobic actinomycetes using both the MALDI-TOF MS manufacturer's supplied database(s) and a c

249 - H](+) and [M(*)](+) ions are formed by the MALDI process, explaining why they were not observed wit

250 ich nanomaterials can be used to enhance the MALDI-based detection of biomolecules.

251 In tissue imaging experiments, the MALDI/ESI interface has been employed in experiments wit

252 Structures and schemes are proposed for the MALDI fragment ions associated with each precursor ion.

253 by decreasing the number of analytes in the MALDI plume and reducing adduct formation in the resulti

254 omprehensive data shed useful light into the MALDI mechanisms and could assist in further methodologi

255 wavelength-tunable lasers to investigate the MALDI wavelength dependence with a selected set of such

256 data allowed intrasample modification of the MALDI image to make it compatible with the optical image

257 We have found that introduction of the MALDI-generated ions into an electrodynamic dual-funnel

258 ons of the typical lateral variations of the MALDI-MS.

259 uantitation with minimal side reactions: the MALDI-TOF-MS profiles obtained were in good agreement wi

260 lar order of reactivity as observed with the MALDI-TOF mass spectrometry assay.

261 This is the first time MALDI-MSI has been applied for three dimensional chemica

262 AMS intervention included: real-time MALDI-TOF MS pharmacist notification and prospective AMS

263 highly sensitive and specific alternative to MALDI MS for imaging of TAGs from tissue sections.

264 tochastic neighbor embedding were applied to MALDI MS images acquired from tissue which had been samp

265 and AST (42.3 to 40.7 h) results compared to MALDI (P < 0.001).

266 ential interferences that are detrimental to MALDI-MSI, while fixation is undesirable for the analysi

267 ion procedures are generally transferable to MALDI-MSI; however, there are various limitations.

268 vents (water and dimethyl sulfoxide) and two MALDI matrices (2,5-dihydroxybenzoic acid and 2',4',6'-t

269 lar weight interferences observed in typical MALDI but such nanomaterials typically do not improve th

270 his report summarizes the first study to use MALDI-IMS to analyze drug penetration of a liposomal dru

271 We have used MALDI-MSI to study the spatial distribution of two major

272 We used MALDI- mass spectrometry imaging to identify discrete ti

273 sponding to pre-TLA and post-TLA, both using MALDI-TOF MS for organism identification.

274 ticosteroid drug in human OA cartilage using MALDI-MSI.

275 Data gathered using MALDI-MSI was verified through gas chromatography analys

276 nd 1 acylglycerol) in complex mixtures using MALDI-TOF-MS with fractional factorial design (FFD) and

277 Now, using MALDI-TOF mass spectrometry, we report that transmembran

278 plication highlights the challenges of using MALDI-TOF mass spectrometry for purposes other than orga

279 tes were found at the inhibition zones using MALDI IMS and were identified using MS/MS molecular netw

280 linical microbiology laboratories to utilize MALDI-TOF MS for the rapid identification of clinically

281 report, we survey an approach that utilizes MALDI coupled with an automated sample preparation to co

282 uate the impact of MALDI-TOF MS alone versus MALDI-TOF MS combined with real-time, pharmacist-driven,

283 with positive blood cultures identified via MALDI-TOF MS combined with prospective AMS intervention

284 MICs against all Exophiala isolates in vitro MALDI-TOF MS successfully distinguished all 18 species a

285 susceptibility testing might be useful when MALDI-TOF MS results in an organism identification, and

286 otein described in this study was SOD, while MALDI-TOF analysis confirmed only SOD from erythrocytes.

287 tervention compared to a control cohort with MALDI-TOF MS identification without AMS intervention.

288 nd peptide immunoprecipitation combined with MALDI-MS detection.

289 0, bridging the mass range gap compared with MALDI.

290 on times (<30 s/200 mum), compatibility with MALDI, universal sample compatibility, high spatial spec

291 by this technique are fully compatible with MALDI ionization because the metal-based substrates are

292 both fixed and fresh tissue compatible with MALDI-MSI and histology is desirable to increase the bre

293 tantly, endo-beta-galactosidase coupled with MALDI-MS allowed these two epitopes, for the first time,

294 by applying carbohydrate arrays coupled with MALDI-ToF mass spectrometry to identify reaction product

295 However, analyte coverage with MALDI MSI is typically limited to the more abundant comp

296 lipid and small molecule distributions with MALDI-MSI.

297 optimal outcomes, rapid identification with MALDI-TOF MS combined with real-time AMS intervention is

298 combination of immunoprecipitation (IP) with MALDI technology delivers high assay sensitivity and spe

299 tered chemotherapeutics and metabolites with MALDI-imaging mass spectrometry.

300 In this work MALDI-TOF mass spectroscopy was investigated to characte