ライフサイエンスコーパス: MALT lymphoma

1 phoepithelial lesions, a hallmark of gastric MALT lymphoma.

2 may eventually develop into low-grade B-cell MALT lymphoma.

3 olution of H. pylori-associated gastritis to MALT lymphoma.

4 is associated with HP dependence of gastric MALT lymphoma.

5 atients with an increased risk of developing MALT lymphoma.

6 tion signature to that of the salivary gland MALT lymphoma.

7 varying size in four patients with low-grade MALT lymphoma.

8 patients initially diagnosed elsewhere with MALT lymphoma.

9 ic marginal zone in a single case of gastric MALT lymphoma.

10 bacter pylori-positive gastritis and gastric MALT lymphoma.

11 of-function mechanism in the pathogenesis of MALT lymphoma.

12 iological, and molecular genetic features of MALT lymphoma.

13 ular mechanisms of primary SS and primary SS/MALT lymphoma.

14 , both proteins are translocation targets in MALT lymphoma.

15 lize and optimize treatment of patients with MALT lymphoma.

16 clinical management of patients with gastric MALT lymphoma.

17 have been implicated in the pathogenesis of MALT lymphoma.

18 gastritis and other low-grade gastric B-cell MALT lymphomas.

19 cosal B-cell traffic are also operational in MALT lymphomas.

20 come in the management of gastric, low-grade MALT lymphomas.

21 clones of concurrent gastric and intestinal MALT lymphomas.

22 nt role in the clonal expansion of low-grade MALT lymphomas.

23 the time being in patients with other non-GI MALT lymphomas.

24 otic therapy in nongastrointestinal (non-GI) MALT lymphomas.

25 alternative to radiotherapy for conjunctival MALT lymphomas.

26 not as favorable as the treatment results of MALT lymphomas.

27 a state-of-the-art summary of ocular adnexal MALT lymphomas.

28 c signaling and implicate its dysfunction in MALT lymphomas.

29 on to the IGH locus can promote formation of MALT lymphomas.

30 ll these low-grade lesions are classified as MALT lymphomas.

31 pathogenetic pathways in the development of MALT lymphomas.

32 ased on the distinction between MALT and non-MALT lymphomas.

33 cation of mucosa-associated lymphoid tissue (MALT) lymphoma.

34 2;q32) of mucosa-associated lymphoid tissue (MALT) lymphoma.

35 cation in mucosa-associated lymphoid tissue (MALT) lymphoma.

36 cation in mucosa-associated lymphoid tissue (MALT) lymphoma.

37 lmarks of mucosa-associated lymphoid tissue (MALT) lymphoma.

38 gastric mucosae-associated lymphoid tissue (MALT) lymphoma.

39 s in some mucosa-associated lymphoid tissue (MALT) lymphomas.

40 ations in mucosa-associated lymphoid tissue (MALT) lymphomas.

41 Studies on the use of doxycycline for MALT lymphomas (137 patients) reported complete response

42 igin) and mucosa-associated lymphoid tissue (MALT) lymphoma (19 of 45 = 42%) (postgerminal center), b

43 ar lymphoma (3 cases) and mucosa-associated (MALT) lymphoma (3 cases) strong (2+) pRB staining was li

44 20 (6.7%) mucosa-associated lymphoid tissue (MALT) lymphomas, 4 of 42 (9.5%) follicular lymphomas, an

45 ll clone, whereas 15 of 25 t(11;18)-negative MALT lymphomas (60%) showed trisomy of chromosomes 18 (n

46 can occur, and in studies reporting only on MALT lymphomas (884 patients), the 5-year and 10-year di

47 11 of 12 polymerase chain reaction-positive MALT lymphomas (92%).

48 tiple histologic subtypes of lymphoma or non-MALT lymphomas (988 patients) reported local control rat

49 have high-grade MALT lymphoma with low-grade MALT lymphoma abutting the tumor.

50 Thirty-seven MALT lymphomas (all previously evaluated for t(11;18) by

51 is work establishes a molecular link between MALT lymphoma and ABC-DLBCL, and provides mouse models t

52 niques have aided in the distinction between MALT lymphoma and other lymphoproliferative disorders an

53 howed the same sized dominant product in the MALT lymphoma and the follicular lymphoma.

54 (q21;q21) translocation occurs frequently in MALT lymphomas and creates a chimeric NF-kappaB-activati

55 t(11;18)(q21,q21) is found in 30% of gastric MALT lymphomas and is associated with a failure to respo

56 ximab for mucosa-associated lymphoid tissue (MALT) lymphoma and steroids for prolonged cough.

57 ge cell lymphoma (LCL) arising subsequent to MALT lymphoma, and 16 controls were tested by FISH using

58 ts with primary SS, patients with primary SS/MALT lymphoma, and subjects without primary SS (non-prim

59 cosal venules are similar in normal MALT and MALT lymphomas, and factors controlling normal mucosal B

60 mphomas have a more indolent course than non-MALT lymphomas, and in the conjunctiva a more conservati

61 ly in aggressive and antibiotic unresponsive MALT lymphomas, and may further implicate the biologic i

62 on to systemic disease seems high, even with MALT lymphomas, and treatment with radiation is still re

63 disease, mucosa-associated lymphoid tissue (MALT) lymphoma, and gastric adenocarcinoma.

64 Apart from gastric MALT lymphoma, antibiotic therapies have been adequately

65 MALT lymphomas are characterized genetically by the t(11

66 show that concurrent gastric and intestinal MALT lymphomas are derived from the same clone and sugge

67 depth of infiltration of the wall by gastric MALT lymphoma as measured by endoscopic ultrasound has b

68 disease, mucosa-associated lymphoid tissue (MALT) lymphoma, as well as hyperplastic polyps, hyperpla

69 rin-mediated cell adhesion, while primary SS/MALT lymphoma-associated modules were enriched with gene

70 Homing receptor expression in MALT lymphoma B cells was heterogeneous, however, in lin

71 ithin chromosome 18 DNA in three examples of MALT lymphoma bearing this translocation.

72 he LCL and its clonally identical antecedent MALT lymphoma both showed t(11;18).

73 x cases of concurrent gastric and intestinal MALT lymphomas by polymerase chain reaction (PCR) amplif

74 ) and without ("pure" DLBCL) the features of MALT lymphomas, can achieve long-term complete remission

75 cell development, these findings suggest the MALT lymphoma cell of origin may be a germinal center B

76 he LCL had trisomy 12, and a small subset of MALT lymphoma cells had trisomy 3 and/or 12.

77 d from colonization of lymphoid follicles by MALT lymphoma cells, following which the tumor cells wer

78 zone B cells are the normal counterparts of MALT lymphoma cells.

79 r gastric mucosa-associated lymphoid tissue (MALT) lymphoma cells preferentially to localize around r

80 For low-grade MALT lymphomas confined to the gastric wall and without

81 As many as 50% of low-grade MALT lymphomas contain an (11;18)(q21; q21) chromosomal

82 nvolvement of the marginal zone when gastric MALT lymphomas disseminate to the spleen, which is in ke

83 rminal caspase recruitment domain (CARD), in MALT lymphomas due to the recurrent t(1;14)(p22;q32).

84 e management of patients with ocular adnexal MALT lymphoma, especially monoclonal antibody therapy an

85 nd 8 hub genes for distinguishing primary SS/MALT lymphoma from primary SS.

86 f gastric mucosa-associated lymphoid tissue (MALT) lymphoma (GML).

87 chronic gastritis tissue, those with MALT or MALT lymphoma had an increase in PCNA labeling index of

88 mitantly, the BCL10 protein is stabilized in MALT lymphomas harboring this fusion.

89 Importantly, primary MALT lymphomas harbouring the API2-MALT1 fusion uniquely

90 The pathogenesis of gastric MALT lymphoma has been elucidated to a large degree in r

91 gy of the mucosa-associated lymphoid tissue (MALT) lymphomas, has been implicated in inflammatory pro

92 MALT lymphomas have a more indolent course than non-MALT

93 In gastric MALT lymphoma Helicobacter pylori is the most common sti

94 . pylori-associated follicular gastritis and MALT lymphomas high endothelial venules coexpressed muco

95 ents with mucosa-associated lymphoid tissue (MALT) lymphomas (HR = 0.26, 95%CI: 0.11-0.59, p = 0.001)

96 study pathogenesis and treatment of gastric MALT lymphoma in humans.

97 a higher than expected incidence of gastric MALT lymphoma in immunosuppressed transplant recipients

98 iption of mucosa-associated lymphoid tissue (MALT) lymphoma in 1983 rapid advances have been made in

99 low-grade mucosa-associated lymphoid tissue (MALT) lymphoma in the parotid gland.

100 have been associated with the development of MALT lymphoma including t(11;18) and alterations in Bcl-

101 A subset of H. pylori-positive gastric MALT lymphomas, including infiltrative tumors, may respo

102 1;q21) in mucosa-associated lymphoid tissue (MALT) lymphoma induces proteolytic cleavage of NF-kappaB

103 The MALT-lymphoma International Prognostic Index (MALT-IPI)

104 Gastric MALT lymphoma is a model malignancy for examination of h

105 When low-grade MALT lymphoma is suspected on the basis of barium study

106 be involved in the growth of salivary gland MALT lymphomas is further suggested by the noted restric

107 f gastric mucosa-associated lymphoid tissue (MALT) lymphoma is dependent on Helicobacter pylori infec

108 Gastric mucosa-associated lymphoid tissue (MALT) lymphoma is indolent and often associated with Hel

109 Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common extranodal lymphoid ce

110 Mucosa-associated lymphoid tissue (MALT) lymphoma is the most common extranodal lymphoid ne

111 enesis of mucosa-associated lymphoid tissue (MALT) lymphomas is associated with independent chromosom

112 g gastric mucosa-associated lymphoid tissue (MALT) lymphoma linked with Helicobacter pylori infection

113 For MALT lymphomas, local control, disease-free survival, an

114 API2-MALT1-positive MALT lymphomas manifest antibiotic resistance and aggres

115 Mucosa-associated lymphoid tissue (MALT) lymphomas most frequently involve the gastrointest

116 h gastric mucosa-associated lymphoid tissue (MALT) lymphoma, much less is known about the value of an

117 Among low-grade gastric MALT lymphoma, mutations were found in 3 of 11 tumors th

118 chronic gastritis (n = 7), MALT (n = 12), or MALT lymphoma (n = 12) were undertaken.

119 pulmonary mucosa-associated lymphoid tissue (MALT) lymphoma (n = 33) and compared the results to GEP

120 The majority of data were available for MALT lymphoma of the ocular adnexa (OAML) including a to

121 Mucosa-associated lymphoid tissue (MALT) lymphoma of the stomach (MLS) has recently been de

122 lymphoma (FL), marginal zone lymphoma (MZL), MALT lymphoma or B-small lymphocytic lymphoma (B-SLL) ce

123 s in early MESA-associated lesions represent MALT lymphomas or more benign types of expansions has be

124 have furthered the understanding of gastric MALT lymphoma pathogenesis, clinical behavior, and treat

125 , accessible, and effective tool to identify MALT lymphoma patients at risk of poor outcomes.

126 obtained by merging 3 independent cohorts of MALT lymphoma patients.

127 r adnexal mucosa-associated lymphoid tissue (MALT) lymphoma (POAML) is the most common orbital tumor,

128 with antibiotics can be followed by gastric MALT lymphoma regression in most cases.

129 oma occurred 6 months after excision and the MALT lymphoma remained indolent during the course of her

130 ier work in establishing that salivary gland MALT lymphomas represent a highly selected B-cell popula

131 s for the treatment of patients with gastric MALT lymphoma requiring further treatment beyond H pylor

132 ts with primary SS and those with primary SS/MALT lymphoma revealed pathways and molecular targets as

133 anaplastic large cell (Ki-1+) lymphoma, 0/2 MALT lymphoma) showed hypermethylation of the promoter.

134 High-grade MALT lymphoma tended to show a slightly higher mutation

135 Early-stage, low-grade gastric MALT lymphoma that was associated with Helicobacter pylo

136 Frequent use of V1-69 appears to differ from MALT lymphomas that develop at other sites.

137 the transformation of H. pylori gastritis to MALT lymphoma, the extent of cell proliferation, cell vi

138 g the translocation t(1;18)(q21;q21) forms a MALT lymphoma, the growth of which is independent of H.

139 s efficacy on high-grade transformed gastric MALT lymphomas, the DLBCL(MALT).

140 AI was 3.4- and 1.4-fold higher in MALT and MALT lymphoma tissue, respectively, in the same comparis

141 he AI and Cdc2/Cdk1 or cyclin B1 in MALT and MALT lymphoma tissues.

142 ed tumor onset and induced transformation of MALT lymphoma to activated B-cell diffuse large-cell lym

143 his truly represented preferential homing of MALT lymphoma to the splenic marginal zone, we have now

144 Another MALT lymphoma translocation, t(11;18)(q21;q21), fuses th

145 The results of treatment of non-MALT lymphomas using radiotherapy also were good, but th

146 On the other hand, the AI index of MALT lymphoma was 2.5-fold lower than that for MALT tiss

147 ntibacterial therapy in patients with non-GI MALT lymphomas was performed.

148 orambucil Plus Rituximab Versus Rituximab in MALT Lymphoma) was launched to compare chlorambucil alon

149 medical records of six patients with gastric MALT lymphoma were retrospectively reviewed.

150 our liver transplant recipients with gastric MALT lymphoma were reviewed.

151 modules related to primary SS and primary SS/MALT lymphoma were significantly enriched with genes kno

152 (VH and VL) expressed by five salivary gland MALT lymphomas were cloned and sequenced.

153 een adequately tested only in ocular adnexal MALT lymphomas where upfront doxycycline may be a reason

154 ecutive patients with stage I to IIE gastric MALT lymphoma who obtained a pathologic remission after

155 t endoscopy demonstrated early-stage gastric MALT lymphoma with associated Helicobacter pylori gastri

156 latter patient was found to have high-grade MALT lymphoma with low-grade MALT lymphoma abutting the

157 Only one other MALT lymphoma with t(11;18) showed aneuploidy (trisomy 3

158 The local control rate of MALT lymphomas with treatments involving radiotherapy av

159 ry showed mucosa-associated lymphoid tissue (MALT) lymphoma with immunoglobulin kappa monotype.