ライフサイエンスコーパス: MBP

1 MBP adsorbs on normal bilayers to form a compact film (3

2 MBP conjugated fluorescent dye-encapsulating liposomes s

3 MBP is an abundant myelin protein involved in demyelinat

4 MBP is loosely accommodated in the HLA-DR4-binding groov

5 MBP mRNA is sorted into RNA granules that are transporte

6 MBP preferentially adsorbs to liquid-disordered submicro

7 MBP then folds to the native state on a longer time scal

8 MBP with or without antibiotics was associated with redu

9 MBP with oral antibiotics reduces by nearly half, SSI, a

10 MBP+/ABX+ was also associated with lower anastomotic lea

11 MBP-1 immune serum significantly inhibited M. avium subs

12 MBPs, including the thermostable PfuMBP, have been demon

13 reparation type: 14.9% no preparation, 12.0% MBP, and 6.5% OABP (P < 0.001).

14 e encoding microaggregate-binding protein 1 (MBP-1) (MAV_3013) is highly expressed during microaggreg

15 ranules (by mass) are major basic protein 1 (MBP-1) and eosinophil peroxidase (EPX).

16 Gelatin-MBP and gelatin-TiO(2)-MBP electrodes were prepared by chemical immobilization

17 ween Anti-MBP and gelatin-MBP/gelatin-TiO(2)-MBP immunosensor is quasireversible.

18 ansfer reaction occurs on the gelatin-TiO(2)-MBP immunosensor surface.

19 for gelatin-MBP and 46 s for gelatin-TiO(2)-MBP immunosensor).

20 Gelatin-MBP and gelatin-TiO(2)-MBP immunosensors have detection limit of 0.1528 ng ml(-

21 P confined on gelatin-MBP and gelatin-TiO(2)-MBP surfaces are estimated to be 195 and 205 mV, respect

22 ents, 2296 (27.2%) had no-prep, 3822 (45.3%) MBP+/ABX-, and 2324 (27.5%) MBP+/ABX+.

23 Thus, the MS2-3C8-MBP-DR4 complex reveals the basis for an alternative str

24 SI [MBP+/ABX+: OR = 0.39, 95% CI: 0.32-0.48; MBP+/ABX-: OR = 0.80, 95% CI: 0.69-0.93] versus no-prep.

25 ep, 3822 (45.3%) MBP+/ABX-, and 2324 (27.5%) MBP+/ABX+.

26 57, 95% confidence interval (CI): 0.48-0.68; MBP+/ABX-: OR = 0.78, 95% CI: 0.68-0.91] and SSI [MBP+/A

27 g resources to rapidly characterize abundant MBP proteoforms within murine tissue.

28 reoperative MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-), and no bowel preparation (no-prep

29 Following eosinophil activation, MBP-1 toxicity is triggered by granule acidification, fo

30 In addition, MBP dimers form a correlated mesh-like network within th

31 ion with soluble FasL levels in the airways, MBP(+) eosinophils remained TUNEL negative in the submuc

32 All MBP-NDM-1 fusion proteins were soluble; however, only on

33 MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-), and no bowel preparation (no-prep) on outcom

34 ype cerebellar neurons in the presence of an MBP antibody or L1 peptide containing the MBP cleavage s

35 th eosinophils killing the larvae through an MBP-dependent mechanism and neutrophils killing the worm

36 that eosinophils kill the larvae through an MBP-dependent mechanism in the primary immune response i

37 On multivariable analysis, MBP with antibiotics, but not without, was independently

38 three p38alpha substrates (ATFII, Elk-1, and MBP) with no apparent effect on the phosphorylation of M

39 Binding scores with SA-CAP-2 and MBP-CAP-1 to MBP-CAP-4 were generally lower but strongly

40 maximizing interactions between MS2-3C8 and MBP.

41 During pregnancy, MEP (ICC = 0.50) and MBP (ICC = 0.45) were less variable than BPA (ICC = 0.12

42 It is associated with hnRNP A2 and MBP mRNA in cytoplasmic granular structures and is invol

43 Thermodynamic analysis of numerous GA and MBP variants suggests that the key to our approach invol

44 PGC1alpha and its targets HmgcS1, Hmgcr, and MBP.

45 urine sample may reasonably classify MEP and MBP concentrations during pregnancy, but more than one s

46 ampus, whereas reductions in CD200, NGF, and MBP were evident.

47 preparation: none, MBP only, OABP only, and MBP plus OABP adjusting for other covariates.

48 outcome and performed better than S100B and MBP.

49 two well-studied blood biomarkers, S100B and MBP.

50 the interactions between the transporter and MBP in nanodiscs and in detergent.

51 med in situ by using toluidine blue, an anti-MBP antibody, and transmission electron microscopy (TEM)

52 cate that the electron transfer between Anti-MBP and gelatin-MBP/gelatin-TiO(2)-MBP immunosensor is q

53 ethod for the specific determination of Anti-MBP in human cerebrospinal fluid (CSF) and serum samples

54 The newly developed GO/pPG/anti-MBP/anti-Tau nanoimmunosensor has been established by im

55 utoantibody, Anti-Myelin Basic Protein (Anti-MBP) was developed by immobilization of MBP on Gelatin a

56 Using anti-MBP-1 immune serum, microaggregate binding to HEp-2 cell

57 impact of preoperative MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-), and no bowel preparat

58 and treatment with atypical antipsychotics, MBP and lamotrigine, and H-FABP and lithium.

59 We report here that an Arabidopsis MBP-1-like protein (AtMBP-1) is alternatively translated

60 ocal microscopy, microaggregates, as well as MBP-1, induced vimentin polymerization at the site of ba

61 Conversely, MS2-3C8 binds MBP-DR4 as tightly as the most avid anti-microbial TCRs.

62 chlorinated methyl- and dimethyl bipyrroles (MBPs and DMBPs) were the most abundant natural products.

63 brane pathway with a polarity such that both MBP and MalFGK2 contribute to the overall substrate sele

64 emi-open MalK2 conformation by maltose-bound MBP is key to the coupling of maltose transport to ATP h

65 Maltose-bound MBP promotes the transition to the semi-open state of Ma

66 ll engagement of both lobes of maltose-bound MBP unto MalFGK2 is facilitated by nucleotides and stabi

67 nd in the cytosolic myelin sheath and bovine MBP (bMBP) leads to an atheronal concentration-dependent

68 icrometer-sized domains that were induced by MBP in live epithelial PtK2 cells.

69 ns of VPS34, VPS15, and BECN1 were mapped by MBP tagging.

70 o North American marine mammals, chlorinated MBPs and DMBPs were more abundant than their brominated

71 ngle spot urine sample adequately classified MBP and MEP concentrations during pregnancy.

72 0), and mature oligodendrocyte markers (CNP, MBP) were quantified.

73 Combined MBP plus OABP before elective colectomy was associated w

74 rystal structures of the transporter complex MBP-MalFGK2 bound with large malto-oligosaccharide in tw

75 which axoglial adhesion molecules coordinate MBP synthesis with myelin sheath formation.

76 hwann cell cocultures dramatically decreased MBP and P0 levels and myelin sheath formation without af

77 mRNA distribution and dramatically decreases MBP protein levels.

78 yl-5-oxohexyl) phthalate, MECPP, Sigma DEHP, MBP, and mono-(3-carboxypropyl) phthalate metabolite lev

79 tides in a mutually exclusive manner (either MBP or TCR-derived, but not both) suggest that there is

80 seen to have detection limits of 0.30nM for MBP and 0.15nM for Tau proteins which were sufficient fo

81 e largest effect estimates were observed for MBP and MiBP (49-50% increase in 8-isoprostane with an i

82 ced mRNA levels were confirmed by RT-PCR for MBP, ACTB and TB10.

83 but similar during and before pregnancy for MBP, MEP, and SigmaDEHP.

84 transport cycle, substrate is channeled from MBP into the transmembrane pathway with a polarity such

85 ionation during biosynthesis and is not from MBP degradation.

86 nRNP F in the cytoplasm and its release from MBP mRNA and RNA granules.

87 ormation of membrane stacks all the way from MBP binding onto a single membrane leaflet to the organi

88 xperimentally test this prediction, we fused MBP to a transmembrane domain to properly orient the pro

89 Gelatin-MBP and gelatin-TiO(2)-MBP electrodes were prepared by c

90 Gelatin-MBP and gelatin-TiO(2)-MBP immunosensors have detection

91 ectron transfer between Anti-MBP and gelatin-MBP/gelatin-TiO(2)-MBP immunosensor is quasireversible.

92 ity and low response times (58 s for gelatin-MBP and 46 s for gelatin-TiO(2)-MBP immunosensor).

93 formal potentials of MBP confined on gelatin-MBP and gelatin-TiO(2)-MBP surfaces are estimated to be

94 Because of the high MBP, the delay was increased to 30 h in C2, increasing T

95 , resulting in high T-SUVmax but with higher MBP than in C2.

96 ytic digestions of a biologically active His-MBP tagged version of EsaR highlighted intradomain and i

97 ulosis (MtUGM) was obtained from a dual His6-MBP-tagged MtUGM construct.

98 How MBP-1 toxicity is controlled within the eosinophil itsel

99 Yet, it is not clear how MBP influences the organization and dynamics of the lipi

100 ions and provide structural insight into how MBP regulates Abeta fibrillar assembly.

101 ion for behavior in suicide completers (IL6, MBP, JUN, KLHDC3) steps in a completely independent test

102 tibiotics was associated with reduced ileus [MBP+/ABX+: odds ratio (OR) = 0.57, 95% confidence interv

103 ls but not immature oligodendrocytes impeded MBP mRNA transcription, thereby preventing MBP protein s

104 Activating apoptosis in MBP(+) cells of the developing spinal cord during the fi

105 re of MBP, can lead to structural changes in MBP and a decrease in myelin stability akin to deiminati

106 tes by lentiviral shRNA led to a decrease in MBP, HMGCS1, and Hmgcr mRNAs.

107 ric oxide (NO) and the expression of iNOS in MBP-primed splenocytes.

108 tgrowth and neuronal survival are reduced in MBP-deficient cerebellar neurons and in wild-type cerebe

109 These studies identify key residues in MBP and Abeta involved in their interactions and provide

110 enesis of the proteolytically active site in MBP or of the MBP cleavage site within L1 as well as ser

111 ound to upregulate Foxp3 and enrich Tregs in MBP-primed T cells.

112 ain, and PGC1alpha over-expression increased MBP and SREBP-2 promoter activity, suggesting that PGC1a

113 ber of mature oligodendrocytes and increases MBP, leading to remyelination and functional recovery of

114 Furthermore, knockdown of hnRNP-K inhibits MBP protein synthesis during myelination.

115 lows for the selective cleavage of MBP3 into MBP and MBP2.

116 Here we show how intragranular MBP-1 nanocrystals restrain toxicity, enabling its safe

117 haracterization workflow resolved four known MBP ASVs and hundreds of differentially modified states

118 s, with reduced myelin basic protein levels (MBP) compared to levels in the C57Bl/6 mouse.

119 anes with modified lipid composition and low MBP concentration, as in demyelinating disease, show str

120 lin genes, such as proteolipid protein, MAG, MBP, and myelin oligodendrocyte glycoprotein, were rapid

121 Like mammalian MBP-1, this truncated form of LOS2 has little, if any, e

122 ssion and differentiation of OPC into mature MBP-expressing oligodendrocytes.

123 vented the cells from developing into mature MBP-positive oligodendrocytes.

124 nonallergenic maltose-binding protein (MBP; MBP-CAP-1 to 4) and binding to a panel of 4 recombinant

125 reatinine- normalized concentrations of MEP, MBP, MEOHP, MEHHP, SigmaLMWP and SigmaHMWP.

126 r approach involved stabilizing the modified MBP and OspA subdomains via external interactions with n

127 pearance of multi-branched 'pre-myelinating' MBP+ / PLP+ oligodendrocytes that interact with axons bu

128 d effector CD8(+) T cells ex vivo, and naive MBP-specific CD8(+) T cells were activated in the CNS du

129 markers SOX10, KROX20 (EGR2), p75NTR (NGFR), MBP and S100B by day 4 in virtually all cells, and matur

130 ased on the type of bowel preparation: none, MBP only, OABP only, and MBP plus OABP adjusting for oth

131 f the expression of signatory genes of O1(+)/MBP(+) OLs and their cellular populations.

132 Genetic ablation of MBP in shiverer mice and mutagenesis of the proteolytica

133 The absence of MBP results in the loss of almost all compact myelin in

134 Moreover, the absence of MBP-1 and EPX promoted a concomitant loss of eosinophil

135 Administration of MBP/OABP before elective colectomy reduces the incidence

136 The association of MBP with lipid membranes has been studied for decades, b

137 Cleavage resulted in covalent attachment of MBP-VirD2 to the 5'-cleaved end, consistent with convent

138 ing mode compensates for the weak binding of MBP to HLA-DR4 by maximizing interactions between MS2-3C

139 e that the initiation of the biosynthesis of MBP mRNA relies on a syntaxin 4-dependent mechanism, whi

140 odendrocytes was able to rescue the block of MBP mRNA transcription in syntaxin 4-downregulated cells

141 ding protein hnRNP F as a novel component of MBP mRNA transport granules.

142 ssue damage under pathological conditions of MBP-1 oversecretion.

143 ole for ERK2 in the translational control of MBP, a myelin protein that appears critical for ensuring

144 expression constructs for crystallization of MBP fusion proteins remains a challenge.

145 ts define hnRNP F as a regulatory element of MBP expression in oligodendrocytes and imply an importan

146 Decreased expression of MBP and deficient myelination were found postnatally and

147 air was reflected in decreased expression of MBP and proteolipid protein and a reduction in the total

148 IRAK1 and TRAF6 and decreased expression of MBP.

149 membrane bilayers, only the liganded form of MBP efficiently stimulates its activity.

150 ings provide evidence for novel functions of MBP in the nervous system.

151 Enzymatic deimination prevents hydrolysis of MBP by the proteasome, suggesting that an abnormally bas

152 or has been established by immobilization of MBP and Tau antibodies.

153 Anti-MBP) was developed by immobilization of MBP on Gelatin and Gelatin-Titanium Dioxide (TiO(2)) mod

154 of Erk2 also resulted in decreased levels of MBP, indicating a cell-autonomous effect of ERK2 in the

155 otein (Mbp) gene with an accelerated loss of MBP that correlates with a lack of myelin sheath formati

156 t differences in the adsorption mechanism of MBP.

157 h effectively reduces the cationic nature of MBP, can lead to structural changes in MBP and a decreas

158 ed OL maturation by increasing the number of MBP(+) cells significantly (p<0.01).

159 e formation of an amorphous protein phase of MBP between two membrane bilayers and provide a molecula

160 ositioned near the maltose-binding pocket of MBP.

161 The formal potentials of MBP confined on gelatin-MBP and gelatin-TiO(2)-MBP surfa

162 The practice of MBP alone should be abandoned.

163 To increase the success rate of MBP-facilitated crystallization, a series of expression

164 volved in post-transcriptional regulation of MBP expression.

165 y, which limits understanding of the role of MBP microheterogeneity in human physiology and disease.

166 The peak separations of MBP (150 mV and 110 mV s(-1) at 100 mV s(-1)) and the as

167 e known separation of the N and C termini of MBP than FRET.

168 of hnRNP A2 and to increased translation of MBP mRNA.

169 SSI is on causal pathway between the use of MBP/OABP and the reduction of other postoperative compli

170 s-acting A2-response element in the 3'UTR of MBP mRNA.

171 The affinity of MBPs is dependent on a large number of factors including

172 e variety of forces governing the binding of MBPs to active site metal ions.

173 We also consider possible sources of MBPs in light of these results.

174 select mutations on the kinetics of the off7-MBP interaction.

175 n basic protein expressing oligodendrocytes (MBP-iCP9).

176 Moreover, the region on MBP responsible for this activity was localized to the 6

177 on proteins were soluble; however, only one, MBP-NDM-1Delta36, exhibited high activity and bound 2 eq

178 mice containing a single deficiency of only MBP-1 or EPX, the absence of both granule proteins resul

179 By P21, MBP expression was restored to wild-type levels, demonst

180 entified from a metal-binding pharmacophore (MBP) library screen.

181 of a series of metal-binding pharmacophores (MBPs) related to the ligand 1-hydroxypyridine-2-(1H)-thi

182 f a library of metal-binding pharmacophores (MBPs) revealed that 8-thioquinoline (8TQ, IC50 value app

183 tabolites as well as mono-n-butyl phthalate (MBP) and monoiso-butyl phthalate (MiBP).

184 yl phthalate (MBzP), mono-n-butyl phthalate (MBP), and monoisobutyl phthalate (MiBP), compared with d

185 hyl phthalate (MEP), mono-n-butyl phthalate (MBP), mono-iso-butyl phthalate, monobenzyl phthalate (MB

186 yl phthalate (MiBP), mono-n-butyl phthalate (MBP), monobenzyl phthalate (MBzP), monoethyl phthalate (

187 (MECPP), as well as mono-n-butyl phthalate (MBP), were significantly higher in cases compared with c

188 oethyl phthalate (MEP), monobutyl phthalate (MBP), monobenzyl phthalate (MBzP), mono (2-ethylhexyl) p

189 Despite robust developmental plasticity, MBP-iCP9-induced oligodendrocyte apoptosis compromised t

190 G activity below the mediastinal blood pool (MBP) uptake.

191 max) and T-SUVmax-to-mediastinum blood-pool (MBP) SUVmean ratios (T/MBP) were determined.

192 erentiated to myelin basic protein-positive (MBP(+)) oligodendrocytes.

193 rectal resection, the impact of preoperative MBP and antibiotics (MBP+/ABX+), MBP alone (MBP+/ABX-),

194 ion, 44.9% had mechanical bowel preparation (MBP) only, and 29.5% received OABP.

195 d MBP mRNA transcription, thereby preventing MBP protein synthesis.

196 elay in the expression of the myelin protein MBP was observed in the corpus callosum at postnatal day

197 nophil granule products major basic protein (MBP) and eosinophil peroxidase (EPO), it was determined

198 idespread reduction of myelin basic protein (MBP) and myelin in the sensorimotor cortex, the stratum

199 eous quantification of Myelin Basic Protein (MBP) and Tau proteins in cerebrospinal fluid (CSF) and s

200 sed on the autoantigen myelin basic protein (MBP) and the MBP-derived peptide MBP85-99 presented to t

201 to a self-peptide from myelin basic protein (MBP) and the multiple sclerosis-associated MHC molecule

202 tocortex, and requires myelin basic protein (MBP) as its major structural component.

203 Here we show that myelin basic protein (MBP) binds to L1 in a Lewis(x)-dependent manner.

204 ed an amplification of myelin basic protein (MBP) expression and differentiation of OPC into mature M

205 image-based screen for myelin basic protein (MBP) expression using primary rat optic-nerve-derived pr

206 sensitive impedimetric Myelin Basic Protein (MBP) immunosensor for the determination of a Multiple Sc

207 Myelin basic protein (MBP) is a major component of central nervous system (CNS

208 eviously reported that myelin basic protein (MBP) is a potent inhibitor of Abeta fibrillar assembly.

209 and concentrations of myelin basic protein (MBP) on the structure of model lipid bilayers, as well a

210 (TCR) specific for the Myelin Basic Protein (MBP) peptide Ac1-9, making the animals susceptible to ex

211 , mostly occupied by a myelin basic protein (MBP) phase.

212 Myelin basic protein (MBP) plays an important structural and functional role i

213 -eGFP-NTR tadpoles the myelin basic protein (MBP) regulatory sequences, specific to mature oligodendr

214 net positive charge of myelin basic protein (MBP) via deimination of arginine to citrulline has been

215 MHC class I-restricted myelin basic protein (MBP) was presented by oligodendrocytes and cross-present

216 igodendrocytes forming myelin basic protein (MBP)(+) and proteolipid protein-positive myelin was impa

217 e mediators, eosinophil major basic protein (MBP), a hallmark of allergy, is particularly important b

218 that the expression of myelin basic protein (MBP), a myelin-specific protein that is synthesized "on

219 a key sheath protein, myelin basic protein (MBP), by reversing the inhibitory effect of the mRNA 3'U

220 ltiple sclerosis (MS), myelin basic protein (MBP), critical for the maintenance of myelin compaction

221 component of myelin is myelin basic protein (MBP), expression of which requires anterograde mRNA tran

222 yered membrane sheath, myelin basic protein (MBP), is hydrolyzed by the 26S proteasome in a ubiquitin

223 nt light chain (NF-L), myelin basic protein (MBP), S100B, and heart-type fatty acid binding protein (

224 s and weakly in mature myelin basic protein (MBP)-positive oligodendrocytes.

225 anied by a decrease in myelin basic protein (MBP).

226 ncluding the eosinophil major basic protein (MBP-1).

227 ntly expressed maltodextrin-binding protein (MBP) are shown here to be well-suited for this purpose.

228 A periplasmic maltose-binding protein (MBP) delivers maltose to the transmembrane subunits (Mal

229 osensor, comprising maltose binding protein (MBP) flanked by a green fluorescent protein (GFP(2)) at

230 tructed, comprising maltose binding protein (MBP) flanked by a green fluorescent protein (GFP(2)) at

231 nstead utilized the maltose binding protein (MBP) in lieu of an antibody in an ELISA.

232 Even though the maltose-binding protein (MBP) is one of the most commonly used crystallization ch

233 SF-Fc) and with the maltose binding protein (MBP) tag at the N-terminus and expressed it as a soluble

234 these measurements, maltose binding protein (MBP) was isotopically labeled with (13)C and (15)N, perm

235 e proteins, pepsin, maltose binding protein (MBP), and carbonic anhydrase (CA) in the presence of hun

236 : calmodulin (CaM), maltose-binding protein (MBP), and dihydrofolate reductase (DHFR).

237 -transferase (GST), maltose-binding protein (MBP), N-utilisation substance protein A (NusA), human pr

238 of sugar binding to maltose-binding protein (MBP), the periplasmic binding protein, does not fully ac

239 ystal structures of maltose binding protein (MBP)-fused AID alone and in complex with deoxycytidine m

240 aracterized several maltose binding protein (MBP)-NDM-1 fusion proteins with different N-termini (ful

241 ne subdomain within maltose binding protein (MBP, alpha/beta/alpha-sandwich) and another within outer

242 The tumor suppressor c-myc binding protein (MBP-1), which is alternatively translated from the secon

243 he large two-domain maltose binding protein (MBP; 370 residues) was studied at high structural resolu

244 2) or nonallergenic maltose-binding protein (MBP; MBP-CAP-1 to 4) and binding to a panel of 4 recombi

245 ssed in schizophrenia (myelin basic protein [MBP], myelin-oligodendrocyte glycoprotein [MOG], beta-ac

246 the adhesive protein (myelin basic protein, MBP) composition.

247 the translation of the major myelin protein, MBP.

248 ff7 and its ligand (maltose binding protein; MBP) is characterized by a hot-spot motif in which bindi

249 protein fusion with Plasmodium knowlesi PSD (MBP-His6-Delta34PkPSD) as the enzyme.

250 eceived OABP only, and 5965 (30.3%) received MBP plus OABP.

251 of bowel preparation, 8020 (40.7%) received MBP only, 641 (3.3%) received OABP only, and 5965 (30.3%

252 Patients who received MBP plus OABP had a lower incidence of superficial SSI,

253 Reduced MBP mRNA in schizophrenia replicates findings in other b

254 ctivity, suggesting that PGC1alpha regulates MBP and cholesterol synthesis at the transcriptional lev

255 Here, we demonstrate that the same MBP biosensor can be combined with a microfluidic system

256 ssed in noninvasive Mycobacterium smegmatis, MBP-1 increased the ability of the bacteria to bind to H

257 Moreover, experiments with a soluble MBP-A2 fusion indicate that the interaction between MurA

258 ABX-: OR = 0.78, 95% CI: 0.68-0.91] and SSI [MBP+/ABX+: OR = 0.39, 95% CI: 0.32-0.48; MBP+/ABX-: OR =

259 As a proteasomal substrate, MBP reveals a distinct and physiologically relevant conc

260 ndrocytes were unable to generate sufficient MBP or to maintain the proper myelination during early d

261 In C1, T-SUVmax and T/MBP ranged from 4.09 to 8.93 and 1.39 to 3.72 at 60 min

262 delay to 42 h in C3 decreased T-SUVmax and T/MBP, showing that 30 h was the most favorable delay.

263 sed to 30 h in C2, increasing T-SUVmax and T/MBP.

264 diastinum blood-pool (MBP) SUVmean ratios (T/MBP) were determined.

265 single point mutation in the BRET(2) tagged MBP protein.

266 nalyses, we identify top genes (DISC1, TCF4, MBP, MOBP, NCAM1, NRCAM, NDUFV2, RAB18, as well as ADCYA

267 Unlike many other tags that were tested, MBP significantly enhanced the solubility of the protein

268 Patients with residual uptake higher than MBP uptake but below liver uptake had equally good outco

269 s (53%), the residual uptake was higher than MBP uptake but below the liver uptake in 27 (23%), sligh

270 Furthermore, we demonstrate that MBP is released by murine cerebellar neurons as a sumoyl

271 We previously demonstrated that MBP activates IgE-desensitized rat MC and human lung and

272 d by coimmunoprecipitation, we observed that MBP-1 interacts with the host cytoskeletal protein vimen

273 Our data show that MBP reorganizes lipid diffusion, possibly by preventing

274 Our results suggest that MBP-1 aggregation is important for innate immunity and i

275 th an antivimentin antibody, suggesting that MBP-1 expression is important for M. avium subsp. homini

276 The MBP reduction was limited to transcripts containing exon

277 toantigen myelin basic protein (MBP) and the MBP-derived peptide MBP85-99 presented to the MS-associa

278 branes has been studied for decades, but the MBP-driven formation of the MDL remains elusive at the b

279 inhibitors and an L1 peptide containing the MBP cleavage site abolish generation of the L1 fragment.

280 an MBP antibody or L1 peptide containing the MBP cleavage site.

281 raries of molecules were elaborated from the MBP hits.

282 Furthermore, the MBP variant (80% identical to GA) remained active.

283 Retention of maltose in the MBP binding site in the deletion mutant, as well as inse

284 composed of segments that are distant in the MBP sequence but adjacent in the native protein where th

285 GDNF protein expression was observed in the MBP-halphasyn transgenic mice.

286 lous both in oligodendrocytes and inside the MBP-rich domains of PtK2 cells compared with undisturbed

287 proteolytically active site in MBP or of the MBP cleavage site within L1 as well as serine protease i

288 ive transcriptional start site (ATSS) of the MBP gene as well as a never before characterized S-acyla

289 slower step (7-s time constant), all of the MBP molecules, although initially heterogeneously struct

290 st to myelin sheets in oligodendrocytes, the MBP-induced domains in epithelial PtK2 cells demonstrate

291 he intermediate is an obligatory step on the MBP folding pathway.

292 Thus, the MBP tag is useful for efficient prokaryotic production a

293 Thus, the MBP-hFGF21 construct was further pursued for optimisatio

294 This MBP-stimulated ATPase activity is independent of maltose

295 ng protein upon L1 stimulation and that this MBP cleaves L1 as a serine protease in the L1 extracellu

296 inding scores with SA-CAP-2 and MBP-CAP-1 to MBP-CAP-4 were generally lower but strongly correlated w

297 lFGK2 despite their high binding affinity to MBP.

298 P-K, an mRNA-binding protein, which binds to MBP mRNA and translocates from the nucleus to the myelin

299 ons revealed the recruitment of PGC1alpha to MBP promoter in mouse brain, and PGC1alpha over-expressi

300 Translated MBP exhibits extreme microheterogeneity with numerous al

301 r and distal to the lesion, colocalized with MBP, and abutted Caspr+ profiles, suggesting newly forme