1                                              MCTD-like lung disease also developed in 50% of immunize

2  a closer link between anti-70K immunity and MCTD-like lung disease.

3  cells in autoantibody production in SLE and MCTD.

4   However, TLR-3(-/-) mice failed to develop MCTD-like lung disease when treated with 70K and U1 RNA.

5             Mixed connective tissue disease (MCTD) is a systemic autoimmune disease with significant

6  feature of mixed connective tissue disease (MCTD) is the presence of antibodies against the U1-ribon

7 s [SSc]) or mixed connective tissue disease (MCTD).

8 atient with mixed connective tissue disease (MCTD).

9 our had 4 mixed connective tissue disorders (MCTD).

10 that are homologous to T cells isolated from MCTD patients.

11 atients, 82 (92.1%) had SSc and 7 (7.9%) had MCTD.

12 n (RNP) complex, but other autoantibodies in MCTD have recently been described.

13 en the immunologic and clinical phenomena in MCTD are emerging.

14        The typical core clinical features of MCTD tended to develop over time; features of inflammati

15 genetic, clinical, and serologic findings of MCTD, and the condition rarely evolved into systemic lup

16 en-specific T cells in a new murine model of MCTD.

17 /or infectious agents in the pathogenesis of MCTD have been advanced.

18 A significant number of patients with SSc or MCTD (13.3%) followed up in a community rheumatology pra

19 evelopment of SLE-like nephritis rather than MCTD-like lung disease.

20 nity and target organ injury consistent with MCTD.

21          Longitudinal study of patients with MCTD highlights the impact of pulmonary hypertension on

22                     Similar to patients with MCTD, CD4(+) T cells can be readily identified from 70-k