ライフサイエンスコーパス: MEP

1 MEP concentrations at 5 and 8 y of age were associated w

2 MEP pathway genes have been identified in many biothreat

3 MEP pathway regulation is poorly understood in microorga

4 MEPs could be easily recorded, disappearing after NMB an

5 MEPs decreased by 36 +/- 6% (P < 0.05) from the start of

6 MEPs detect the lowest systemic blood pressure that ensu

7 MEPs evoked from motor cortex were robustly augmented wi

8 MEPs were also measured in one lamb undergoing Neuro-Mus

9 N-11, LIN-13, LIN-15B, LIN-39, MAB-5, MDL-1, MEP-1, PES-1, PHA-4, PQM-1, SKN-1, and UNC-130) at diver

10 Subsequent reduction by NADPH affords MEP.

11 After PAS25 alone, MEP amplitude increased while intracortical circuits did

12 AmtB, a member of the Rh/Amt/MEP superfamily, is responsible for ammonia transport in

13 ibule to the hydrophobic lumen in the Rh/Amt/MEP superfamily.

14 Proteins of the Amt/MEP family facilitate ammonium transport across the memb

15 proposed in which the monoterpene blocks an MEP pathway-dependent protein geranylgeranylation necess

16 tensity below the threshold for provoking an MEP.

17 ic stem cell signature and largely retain an MEP signature.

18 y inactivating HMGR, but possibly targets an MEP-derived isoprenoid involved in the early steps of th

19 ations of BPA (1.53; 95% CI: 1.04, 2.25) and MEP (monoethyl phthalate) (1.72; 95% CI: 1.28, 2.30) at

20 t urine sample adequately classified MBP and MEP concentrations during pregnancy.

21 Moreover, MIP and MEP significantly improved only after magnesium administ

22 Recent advances in both MVA and MEP pathway-based synthetic biology are also illustrated

23 in regulating the formation of both MVA and MEP pathway-derived terpenoid compounds by controlling t

24 titatively follow the cooperation of MVA and MEP reprogrammed upon osmotic stress (sorbitol treatment

25 rculosis DXR (MtDXR) revealed that NADPH and MEP bind to the free enzyme and that the two bind togeth

26 ctober 2014 who underwent OTAAR with DAP and MEPs monitoring and had no IP-SCI.

27 a positive feedback loop in multipotent and MEPs.

28 Health and Food Safety Vytenis Andriukaitis, MEP Sirpa Pietikainen, Chair of the European Parliament

29 Afferent input attenuated PA, but not AP, MEPs during voluntary activity compared with rest.

30 cortical stimulation of corticospinal axons (MEPs and CMEPs, respectively) and the activity in intrac

31 ants and bacteria, other HAD proteins may be MEP pathway regulators.

32 CD71(+) CD105(-) MEPs are erythrocyte-biased MEPs (E-MEPs) and CD71(int/+) CD105(+) cells are EPs.

33 valonate pathway of isoprenoid biosynthesis (MEP pathway), is a clinically validated antimalarial tar

34 on is much more highly enriched for bipotent MEPs than any previously reported subpopulations.

35 However, both MEPs and TEPs were consistently larger when evoked durin

36 During NOGO trials, both MEPs and CMEPs remained unchanged compared to baseline i

37 g and ordered release of NADP(+) followed by MEP.

38 e in Allergy and Airways Diseases, hosted by MEP David Borrelli, and with active participation of the

39 potentiation (LTP) after-effect assessed by MEPs, but did not vary at PPC level.

40 the PAS protocol induced LTD as revealed by MEPs, there was a specific increase of the coherence bet

41 erived population of glia we propose calling MEP glia.

42 CD71(+) CD105(-) MEPs are erythrocyte-biased MEPs (E-MEPs) and CD71(int/+

43 Both CD71(-) CD105(-) and CD71(+) CD105(-) MEPs, at least in vitro, still retained bipotency for th

44 es as well as their common progenitor cells (MEPs).

45 monstrate that cortical and cervicomedullary MEP size was reduced during precision grip compared with

46 In contrast, cervicomedullary MEPs and F-waves remained unchanged across conditions, a

47 le spot urine sample may reasonably classify MEP and MBP concentrations during pregnancy, but more th

48 In all conditions, MEPs in this muscle were elevated upon or following move

49 ains and correlated with individual cortical MEP latency differences.

50 mice exhibited significantly longer cortical MEP latencies (4.5 +/- 0.22 ms versus 3.7 +/- 0.13 ms; P

51 iring caused strong augmentation of cortical MEPs and spinal excitability that lasted up to an hour a

52 otor evoked potentials elicited by cortical (MEPs) and subcortical (CMEPs) stimulation of corticospin

53 from Agrobacterium tumefaciens, which covert MEP to the corresponding eight-membered cyclic diphospha

54 We synthesized five D-MEP analogues-D-erythritol-4-phosphate (EP), D-3-methylt

55 Therefore, conventionally defined MEP are a mixed population, as a minority give rise to m

56 remained unchanged across conditions, as did MEPs evoked during unopposed weak flexion of the index f

57 S--a median of 36 generations in the diploid MEP strain--while the proliferative potential of daughte

58 es was used to inhibit carbon input into DXP/MEP pathway or both input and output.

59 These data indicate that the DXP/MEP pathway is extremely elastic, and the presence of a

60 D-xylulose 5-phosphate reductoisomerase (DXR/MEP synthase).

61 esidual myeloid differentiation capacity; "E-MEP," strongly biased towards erythroid differentiation;

62 CD105(-) MEPs are erythrocyte-biased MEPs (E-MEPs) and CD71(int/+) CD105(+) cells are EPs.

63 monstrate that the size of cortically evoked MEPs in the first dorsal interosseous, but not in the ab

64 Extended MEPs monitoring was independently associated with decrea

65 e studied the independent effect of extended MEPs monitoring on the risk of developing DP-SCI.

66 with ERG in enhancing the expansion of fetal MEPs and megakaryocytic precursors, resulting in hepatic

67 ted the significant increase in elbow flexor MEP observed from rest to non-fatiguing exercise under c

68 These analyses exposed 18 key genes from MEP, SK, phytol recycling and VTE-core pathways highly a

69 Although a functional MEP pathway is essential for plant viability, the underl

70 and quantitation of primary functional human MEPs from granulocyte colony-stimulating factor-mobilize

71 ur results demonstrate that immunophenotypic MEP comprise three distinct subpopulations: "Pre-MEP," e

72 Comparative expression analyses in MEP, MkP, and ErP populations revealed differential expr

73 with 0.5% predicted after placebo; change in MEP: 11.9% predicted after magnesium compared with 0.8%

74 However, no correlation between changes in MEP amplitudes and functional connectivity was detected.

75 d this negatively correlated with changes in MEP size.

76 he effects of PAS25 with further increase in MEP amplitude and led to reduction in SICI and LICI.

77 Although the increase in MEP amplitudes did not differ between the first and seco

78 score and predicted a 254-1,333% increase in MEP and parabens concentrations.

79 Increases in MEP and parabens were generally greater with PCP use wit

80 the Mk lineage, further defining its role in MEP lineage fate.

81 here that miR-150 modulates lineage fate in MEPs.

82 -E fate decision at the single cell level in MEPs and found that short hairpin RNA-mediated MYB knock

83 Parasites lacking PfHAD1 have increased MEP pathway metabolites, particularly the DXR substrate,

84 iTBS over M1 increased MEP amplitudes compared with sham stimulation after each

85 the non-stimulated hemisphere cTBS increased MEPs and reduced SICI, while iTBS reduced MEPs and incre

86 reduced MEPs and SICI whereas iTBS increased MEPs and SICI.

87 and differentiation potential of individual MEP cells.

88 rmacological manipulations of the individual MEP pathway metabolite levels demonstrate the high speci

89 TMS of the left masseteric cortex induced MEPs that were larger in the cMM than the iMM; stimulati

90 -SMA (but not over a control site) inhibited MEPs at an ISI of 40 ms.

91 Post-interventional MEPs were recorded for an hour and compared to sham usin

92 Carbon was rapidly assimilated into MEP pathway intermediates, but not into the mevalonate p

93 This insight into MEP pathway inhibition consequences underlines the risk

94 hat frequent ballet spectators showed larger MEP amplitudes in the arm muscles when watching ballet c

95 Interestingly, larger MEPs were associated with higher levels of GABA in M1, b

96 In addition, left MEPs were suppressed when the right hand was cued, but o

97 Moreover, left MEPs were larger, as soon as the signal appeared, in the

98 During the postcue delay period, left MEPs were suppressed when the left hand had been cued fo

99 (rest and 10, 30, and 70%) left FCR maximal MEP size correlated with absolute changes in SICI.

100 As expected, the maximal MEPs increase with subjects at rest was instead obtained

101 similar during and before pregnancy for MBP, MEP, and SigmaDEHP.

102 d towards erythroid differentiation; and "MK-MEP," a previously undescribed, rare population of cells

103 -2-ethylhexyl (MEHP, 700 nM), and monoethyl (MEP, 1.5muM) phthalates.

104 biotic, and should be effective against most MEP-dependent organisms.

105 idual TMS SI1mV (stimulus intensity for 1 mV MEP amplitude) sensitivity correlated negatively with 1.

106 We recorded myogenic MEPs after transcranial motor cortex stimulation in 6 la

107 y complex and indirectly via the MtDXR.NADPH.MEP complex--the partitioning being dependent on NADPH c

108 nts, the transient generation of MtDXR.NADPH.MEP was observed.

109 P, overcoming flux limitations of the native MEP pathway.

110 Ablation of MEP glia resulted in the absence of myelinating glia alo

111 The application of MEP at the ecosystem scale results in maximum productivi

112 scarriage indicated positive associations of MEP, MEOHP, MEHHP and SigmaHMWP with embryonic loss (dur

113 her creatinine- normalized concentrations of MEP, MBP, MEOHP, MEHHP, SigmaLMWP and SigmaHMWP.

114 e first aimed to evaluate the feasibility of MEP recording in neonatal lambs and test its validity.

115 onsistent with this hypothesis, lethality of MEP pathway inhibition in Arabidopsis thaliana by fosmid

116 r example, the NADPH-dependent production of MEP from 1-deoxy-D-xylulose 5-phosphate in the first com

117 The partially rate-limiting release of MEP occurs via two pathways--directly from the binary co

118 sis was by far (99%) the main carbon sink of MEP pathway intermediates in mature gray poplar leaves,

119 ncluding facilitating mechanistic studies of MEP lineage commitment, improving approaches for in vitr

120 Suppression of MEP/DOXP pathway activity by high CO2 has been explained

121 in (FSM) is light dependent, and toxicity of MEP pathway inhibition is reduced by genetic and chemica

122 ediated MYB knockdown promoted commitment of MEPs to the Mk lineage, further defining its role in MEP

123 itself is sufficient to induce expansion of MEPs in fetal livers.

124 We hypothesized that extension of MEPs monitoring beyond ACI can also help decrease the ri

125 Initial impairment score, presence of MEPs and FA asymmetry were the only predictors of impair

126 We found that the size of MEPs, but not CMEPs, was more suppressed during power gr

127 Notably, the suppression of MEPs was present from the MEP onset, suggesting that ind

128 downstream of Kit to support the survival of MEPs.

129 The proproliferative effect of miR-125b-2 on MEPs accentuated the Gata1s mutation, whereas growth of

130 itory RT, the CS no longer had any effect on MEPs.

131 At and following movement onset, MEPs obtained in the right FCR were smaller in the Visio

132 beneath the threshold of detection in GMP or MEP.

133 Nras(G12D/+)p53(-/-) MEPs are transformed to self-renewing AML-initiating cel

134 ric inhibition correlated with changes in PA MEPs.

135 thod but an ensemble of minimum energy path (MEP) calculations, which found a steep dependence of the

136 hate/1-deoxy-d-xylulose 5-phosphate pathway (MEP/DOXP), and its synthesis is directly related to phot

137 mic manner as their minimum energy pathways (MEPs) are separated by a large barrier.

138 cerebellar rTMS increased cortico-pharyngeal MEP amplitudes (mean bilateral increase 52%, P = 0.007)

139 XP into 2-C-methyl-D-erythritol 4-phosphate (MEP) by consecutive isomerization and NADPH-dependent re

140 pendent 2-C-methyl-D-erythritol 4-phosphate (MEP) isoprenoid pathway, unexpectedly down-regulated the

141 ng the 2-C-methyl-d-erythrithol-4-phosphate (MEP) pathway for isoprenoid biosynthesis offers interest

142 use the 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway for the synthesis of their essential isopre

143 astidic 2-C-methyl-d-erythritol-4-phosphate (MEP) pathway genes, geranylgeranyl diphosphate synthases

144 astidic 2-C-methyl-D-erythritol-4-phosphate (MEP) pathway is one of the most important pathways in pl

145 The 2-C-methyl-D-erythritol 4-phosphate (MEP) pathway leads to the biosynthesis of isopentenyl di

146 e (DXP)/2-C-methyl-D-erythritol 4-phosphate (MEP) pathway of isoprenoid synthesis by end products dim

147 The 2-C-methylerythritol 4-phosphate (MEP) pathway supplies precursors for plastidial isopreno

148 via the 2-C-methyl-d-erythritol 4-phosphate (MEP) pathway.

149 ough the 2C-methyl-D-erythritol 4-phosphate (MEP) pathway.

150 so known as methyl-d-erythritol 4-phosphate (MEP) synthase) is a NADPH-dependent enzyme, which cataly

151 D-3-Methylerythritol-4-phosphate (MEP), the first pathway-specific intermediate in the pat

152 lize the 2C-methyl-D-erythritol 4-phosphate (MEP, 5) pathway for the biosynthesis of isopentenyl diph

153 ate step of the methyl-erythritol phosphate (MEP) pathway for isoprene biosynthesis.

154 athway involving methylerithritol phosphate (MEP) was discovered in the early 1990s.

155 derived from the methylerythritol phosphate (MEP) and shikimate pathways (SK), respectively.

156 tetrapyrrole and methylerythritol phosphate (MEP) biosynthesis pathways, respectively.

157 ntrations in the methylerythritol phosphate (MEP) isoprenoid biosynthetic pathway.

158 y the plastidial methylerythritol phosphate (MEP) pathway and a stress-specific retrograde signal, in

159 esis through the methylerythritol phosphate (MEP) pathway generates commercially important products a

160 The methylerythritol phosphate (MEP) pathway is an essential metabolic pathway found in

161 t enzymes of the methylerythritol phosphate (MEP) pathway of isoprenoid biosynthesis, including the c

162 last step of the methylerythritol phosphate (MEP) pathway which is used for the biosynthesis of essen

163 oids through the methylerythritol phosphate (MEP) pathway, an attractive pathway for antimicrobial dr

164 y the plastidial methylerythritol phosphate (MEP) pathway, elicits the expression of selected stress-

165 tic pathway [the methylerythritol phosphate (MEP) pathway] and a modified mevalonic acid (MVA) pathwa

166 lonate (MVA) and methylerythritol phosphate (MEP) pathways, operating in parallel in plants to genera

167 c acid (MVA) and methylerythritol phosphate (MEP) pathways.

168 native upstream methylerythritol-phosphate (MEP) pathway forming isopentenyl pyrophosphate and a het

169 a the endogenous methylerythritol-phosphate (MEP) pathway, in tandem with the growth of Synechocystis

170 nary concentrations of mono-ethyl phthalate (MEP) decreased by 27.4% (95% CI: -39.3, -13.2) on averag

171 est percent increase in monoethyl phthalate (MEP) was associated with use of cologne/perfume (83%, p-

172 orDEHP) metabolites and monoethyl phthalate (MEP) with child adiposity depended on the timing of expo

173 inary concentrations of monoethyl phthalate (MEP), mono-n-butyl phthalate (MBP), mono-iso-butyl phtha

174 methyl phthalate (MMP), monoethyl phthalate (MEP), monobutyl phthalate (MBP), monobenzyl phthalate (M

175 enzyl phthalate (MBzP), monoethyl phthalate (MEP), monocarboxyisooctyl phthalate (MCOP), monocarboxyi

176 e glial segregation at the motor exit point (MEP) transition zone are unknown.

177 Positive associations between postnatal MEP and summation operatorDEHP concentrations depended o

178 Motor evoked potential (MEP) amplitude, recruitment curve, and intracortical cir

179 through recording of motor-evoked potential (MEP) amplitude.

180 over M1 producing a motor-evoked potential (MEP) in the relaxed hand.

181 uisition of baseline motor evoked potential (MEP) recordings from each site as a measure of excitabil

182 lity as measured by motor-evoked potentials (MEPs) and (2) alters functional connectivity measured us

183 trolling latency of motor evoked potentials (MEPs) and clinical onset of experimental autoimmune ence

184 Motor evoked potentials (MEPs) and motor threshold were recorded from extensor ca

185 lation, we examined motor evoked potentials (MEPs) and the activity in intracortical and subcortical

186 examined in humans motor-evoked potentials (MEPs) and the activity in intracortical circuits (suppre

187 taneously recording motor-evoked potentials (MEPs) and TMS-evoked EEG potentials (TEPs).

188 ess was monitored via TMS-evoked potentials (MEPs) during a 25% MVC.

189 Motor evoked potentials (MEPs) elicited by cortical, but not by subcortical, stim

190 sponse preparation, motor evoked potentials (MEPs) elicited by transcranial magnetic stimulation (TMS

191 erve stimulation on motor-evoked potentials (MEPs) elicited by transcranial magnetic stimulation over

192 humans by measuring motor-evoked potentials (MEPs) in a left finger muscle during motor preparation i

193 ability by means of motor-evoked potentials (MEPs) in both the hand and the arm, because the hand is

194 movement to obtain motor evoked potentials (MEPs) in the muscles of the right forearm.

195 ulus (TS) to elicit motor-evoked potentials (MEPs) in the right hand.

196 T, such that larger motor-evoked potentials (MEPs) measured at rest were associated with faster RTs.

197 Motor evoked potentials (MEPs) monitoring can promptly detect spinal cord ischemi

198 pinal cord in rats; motor evoked potentials (MEPs) were measured from biceps.

199 Motor-evoked potentials (MEPs) were obtained by transcranial magnetic stimulation

200 imulation (TMS), 25 motor-evoked potentials (MEPs) were recorded before, and 10 time points up to 2 h

201 Motor evoked potentials (MEPs) were recorded from contralateral (cMM) and ipsilat

202 Motor-evoked potentials (MEPs) were recorded from the right first dorsal inteross

203 on the amplitude of motor evoked potentials (MEPs), short interval intracortical inhibition (SICI) an

204 d quantification of motor evoked potentials (MEPs).

205 comprise three distinct subpopulations: "Pre-MEP," enriched for erythroid/megakaryocyte progenitors b

206 n 6 h of urine collection strongly predicted MEP and paraben urinary concentrations.

207 During pregnancy, MEP (ICC = 0.50) and MBP (ICC = 0.45) were less variable

208 ssure (MIP) and maximal expiratory pressure (MEP)].

209 The maximum entropy principle (MEP) is a method for obtaining the most likely distribut

210 Maximum entropy production (MEP), rooted in thermodynamics principles, provides a to

211 of the megakaryocyte/erythrocyte progenitor (MEP) population in the bone marrow (BM).

212 S) and megakaryocyte/erythrocyte progenitor (MEP) were significantly reduced in a murine Hspa9-knockd

213 r (CMP), megakaryocyte-erythroid progenitor (MEP), and granulocyte-macrophage progenitor (GMP) cells,

214 sor, the megakaryocyte-erythroid progenitor (MEP), which remains poorly defined.

215 SC) and megakaryocyte-erythroid progenitors (MEP) than low-risk patients, and provided a prognostic m

216 on of megakaryocyte-erythrocyte progenitors (MEPs) in hematopoiesis as a model system.

217 urified megakaryocyte/erythroid progenitors (MEPs) from W41/41 mice and rescued by the SCL transgene.

218 ipotent megakaryocyte/erythroid progenitors (MEPs) give rise to progeny limited to the megakaryocyte

219 f fetal megakaryocyte-erythroid progenitors (MEPs) triggered by trisomy of chromosome 21 and is furth

220 nown as megakaryocyte/erythroid progenitors (MEPs).

221 s) and megakaryocytic/erythroid progenitors (MEPs).

222 ence in megakaryocyte-erythroid progenitors (MEPs).

223 ), and megakaryocytic-erythroid progenitors (MEPs).

224 re we present the mother enrichment program (MEP), an inducible genetic system in which mother cells

225 lones expressed HPV-16 major early promoter (MEP)-initiated mRNAs spliced from viral SD880 directly t

226 ablished that fosmidomycin inhibits purified MEP synthase (DXR) from F. tularensis LVS.

227 tor agonist baclofen by SCI patients reduced MEP size during precision grip to similar levels as unin

228 PAS25 followed by cTBS150 led to reduced MEP amplitude and increased LICI and SICI.

229 In the stimulated hemisphere, cTBS reduced MEPs and SICI whereas iTBS increased MEPs and SICI.

230 ed MEPs and reduced SICI, while iTBS reduced MEPs and increased SICI.

231 hese experiments show that miR-150 regulates MEP fate, and thus establish a role for miRNAs in lineag

232 Highly purified, single MEP cells were analyzed using index fluorescence-activat

233 akefulness and regardless of SO state, sleep MEPs were smaller and delayed whereas sleep TEPs were fu

234 However, neither stable MEPs during aortic clamp interval (ACI) nor absence of I

235 These results suggest that standardized MEP recording and analysis in neonatal lambs is feasible

236 ending volley from motor cortex stimulation, MEPs were more than doubled.

237 ich engages the reticular system, suppressed MEP size during power grip to a lesser extent than durin

238 hat engages the reticular system, suppressed MEP size during power grip to a lesser extent than durin

239 ut significantly (P < 0.001) suppressed test MEPs with an ISI in the range 18-40 ms.

240 cTBS over either right or left M1 and tested MEPs in both hemispheres.

241 Francisella is demonstrated by the fact that MEP pathway mutations are lethal.

242 We hypothesized that MEP pathway inhibition is lethal because a reduction in

243 The MEP has found hundreds of applications in ergodic and Ma

244 The MEP pathway is used by a number of pathogens, including

245 The MEP pathway, which is absent in animals but present in m

246 Additionally, the MEP can provide a cohort of cells at any stage of their

247 f CNS-derived peripheral glia located at the MEP that selectively restrict the migration of OPCs into

248 ear to be almost exclusively supplied by the MEP pathway, and not the mevalonate pathway, in basil gl

249 d suggests new opportunities to engineer the MEP pathway.

250 the suppression of MEPs was present from the MEP onset, suggesting that indirect corticospinal pathwa

251 ate (MEcDP), metabolically isolated from the MEP pathway.

252 A brief overview highlights the MEP pathway's potential as a selective drug target, whic

253 at catalyzes the first committed step in the MEP pathway, producing the essential isoprenoid precurso

254 The antimalarial fosmidomycin inhibits the MEP pathway enzyme deoxyxylulose 5-phosphate reductoisom

255 r long-chain Dols, the relative input of the MEP and MVA pathways remained unchanged, suggesting dive

256 or root axons and an immediate breach of the MEP by OPCs.

257 and the abundance of the first enzyme of the MEP pathway (1-deoxy-D-xylulose 5-phosphate synthase, DX

258 ant mechanism of metabolic regulation of the MEP pathway and indicates that thiamine pyrophosphate-de

259 numerous organisms, makes the enzymes of the MEP pathway attractive drug targets for the development

260 proach helped to unlock the potential of the MEP pathway for the engineered production of terpenoid n

261 th a construct for the overexpression of the MEP pathway gene 1-deoxy-D-xylulose 5-phosphate reductoi

262 hematical model of diurnal regulation of the MEP pathway in Arabidopsis thaliana.

263 The absence of the MEP pathway in humans makes it a promising new target fo

264 The contribution of the MEP pathway increased significantly (reaching 100%) excl

265 The first committed step of the MEP pathway is catalyzed by 1-deoxy-D-xylulose 5-phospha

266 phosphate in the first committed step of the MEP pathway is catalyzed by 1-deoxy-D-xylulose-5-phospha

267 nderstanding the metabolic regulation of the MEP pathway is important considering the numerous applic

268 The effect of different metabolites of the MEP pathway on PtDXS activity was tested.

269 The importance of the MEP pathway to Francisella is demonstrated by the fact t

270 review, we describe the seven enzymes of the MEP pathway, along with their discoveries, three-dimensi

271 is an important regulatory mechanism of the MEP pathway.

272 t DXS is the major controlling enzyme of the MEP pathway.

273 se (IspD), the third catalytic enzyme of the MEP pathway.

274 rol of DXS for the diurnal regulation of the MEP pathway.

275 ary stimulation was used, suppression of the MEP was only evident 1-3 ms after its onset.

276 or LytB) catalyzes the terminal step of the MEP/DOXP pathway where it converts (E)-4-hydroxy-3-methy

277 ew, we summarize mechanistic insights on the MEP pathway enzymes.

278 We demonstrate that the MEP is a perfectly consistent concept for nonergodic and

279 istribution, together with the fact that the MEP pathway is essential in numerous organisms, makes th

280 We propose that the MEP pathway, in addition to producing isoprenoids, funct

281 Therefore, the MEP pathway is a target for the development of new antim

282 e, we analyzed the carbon fluxes through the MEP pathway and into the major plastidic isoprenoid prod

283 Our data show that flux through the MEP pathway is accelerated in light due to the photosynt

284 -methyl-d-erythritol-4-phosphate through the MEP pathway.

285 efore controls substrate availability to the MEP pathway.

286 extend processes into the periphery via the MEP and immediately upon contact with spinal motor root

287 They are synthesized in the plastids via the MEP pathway.

288 y reduced the overall carbon flux within the MEP pathway.

289 (int)/+) CD105(+) subset of cells within the MEP population was completely restricted to the erythroi

290 rpersonal Reactivity Index, the larger their MEPs were in the arms when watching Indian dance.

291 me, which catalyzes the conversion of DXP to MEP in the nonmevalonate pathway of isoprene biosynthesi

292 rythrose phosphate, which is then reduced to MEP by NADPH.

293 of IR in erythroid cells and MKs compared to MEPs.

294 hanced oncogenic Nras signaling to transform MEPs and drive AML development.

295 how that during AML development, transformed MEPs acquire overexpression of oncogenic Nras, leading t

296 equencing analysis revealed that transformed MEPs gain a partial hematopoietic stem cell signature an

297 Notably, during GO trials, MEPs increased to a similar extent in both groups but CM

298 oy a forward genetics approach to understand MEP pathway regulation in the malaria parasite, Plasmodi

299 ndex finger sensory function correlated with MEP size during precision grip in SCI patients.

300 impairment resolved by 70% in patients with MEPs regardless of their initial impairment, and ipsiles