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1 MMC had no effect on acquisition of HSV-2 during 72 mont
2 MMC is irreversible at term.
3 MMC is passively transported and bioreductively activate
4 MMC outperforms ART significantly in cost per infection
5 MMC therapy is a potent inducer of PVOD in humans and ra
6 MMC, although still off-label treatment for ophthalmic s
7 MMC-induced PVOD in rats represents a unique model to te
9 yes treated with surface ablation with 0.02% MMC were compared with nontreated eyes at Vissum Santa H
10 ased locomotor activity was observed after 4-MMC administration in both strains with significantly mo
11 ese results show that the cathinone analog 4-MMC exhibits thermoregulatory and locomotor properties t
12 uction of body temperature was produced by 4-MMC in Wistar rats at 23 degrees C or 27 degrees C with
13 he determination of cathinone derivatives (4-MMC and 4-MEC) in three seized street samples that are i
14 locomotor stimulation produced by 10 mg/kg 4-MMC was nearly identical to that produced by 1 mg/kg d-m
16 vatives mephedrone (4-methylmethcathinone; 4-MMC) and 4'-methyl-N-ethylcathinone (4-methylethcathinon
17 tored after subcutaneous administration of 4-MMC (1-10 mg/kg ) using an implantable radiotelemetry sy
20 ation of DNA-modified electrode in activated MMC led to alterations in DNA and changes in its electro
22 omplete success rates compared to adjunctive MMC; however, the risk of persistent hypotony is higher
24 or in combination with DNA damaging agents (MMC or oxaliplatin) in PDA cell lines that are either DN
27 d endothelial cell density (ECD) reported an MMC-related decrease in ECD, no clinical adverse outcome
28 atients (3.1-20.4 years of age) underwent an MMC-augmented primary trabeculectomy during the period f
31 eriods: prior to the availability of ART and MMC (1999-2004), during early availability of ART and MM
32 -2004), during early availability of ART and MMC (2004-2007), and during mature program scale-up (200
33 l Rakai communities, community-level ART and MMC coverage, sociodemographics, sexual behaviors, and H
35 lymphoblasts were hypersensitive to MMC and MMC-induced monoubiquitination of FANCD2 was impaired.
36 tentially achievable by price reductions and MMC interventions targeting F&V intake in the US populat
37 lig4 double mutants toward high salinity and MMC treatments, indicated the involvement of NHEJ-mediat
38 da knockout mutants toward high salinity and MMC treatments, with higher levels of accumulation of do
41 hea, unlike in skin and intestine, CTMCs and MMCs both express all six serine proteases and CPA3 (mMC
44 deficient RecN(K35A) binds and forms foci at MMC-induced DSBs, but is not released from the MMC-induc
45 is denied differences in bleb height between MMC vs OLO (140.5 +/- 20.3 mu vs 129.2 +/- 19.3 mu respe
50 ending, the $5 billion in savings offered by MMC and ART over TasP in the next decade, for similar he
52 raftment potential of HSPC, and Mitomycin C (MMC) -sensitive hematopoiesis), were absent in Rad18(-/-
53 ncluding the crosslinking agent mitomycin C (MMC) and the replication inhibitor hydroxyurea, but not
56 e FDA-approved anti-cancer drug mitomycin C (MMC) eradicates persister cells through a growth-indepen
57 o underwent trabeculectomy with mitomycin C (MMC) for uncontrolled elevated intraocular pressure (IOP
58 s were used in 400 cases (93%): mitomycin C (MMC) in 271 (63%), 5-fluorouracil (5-FU) in 129 (30%), a
59 surgery to trabeculectomy with mitomycin C (MMC) in eyes with previous cataract and/or failed glauco
62 Rad54(-/-) cells rescued their mitomycin C (MMC) sensitivity, and decreased both the level of DNA da
63 ivity to the DNA damaging agent mitomycin C (MMC) that correlates with delayed repair of MMC-induced
64 y on accurate concentrations of mitomycin C (MMC) to prevent scarring with trabeculectomy surgery.
66 creased cellular sensitivity to mitomycin C (MMC), and in increased levels of spontaneous and MMC-ind
67 tivity to crosslinkers, such as mitomycin C (MMC), we find that they are largely resistant to HU, exc
76 h European-derived race; use of mitomycin C (MMC); higher concentrations of MMC, when used; and highe
77 ot BLM, conferred resistance to mitomycin C (MMC, an interstrand crosslinker) and camptothecin (CPT,
80 s of 7 cases of PVOD induced by mitomycin-C (MMC) therapy from the French Pulmonary Hypertension Regi
84 enarios: (a) a national mass media campaign (MMC) aimed to increase consumption of F&Vs and reduce co
86 rites contain abiotic macromolecular carbon (MMC) phases detected in association with small oxide gra
88 ed sterility, altered Megaspore Mother Cell (MMC) specification, and delayed programmed cell death in
89 tophagy within 1 h in mouse mesangial cells (MMC) as determined by increased microtubule-associated p
90 ific siRNA in primary mouse mesangial cells (MMC), resulted in increased protein levels of type I col
93 CCR2(+) activated myeloid mononuclear cells (MMCs) and the levels of proinflammatory cytokines in the
94 omatal stem cells (meristemoid mother cells [MMCs]) are fundamental for the generation and patterning
95 ents, we designed a multimodality chelation (MMC) scaffold which combined a radiometal chelating agen
96 ing approach with a multimodality chelation (MMC) scaffold would minimize steric effects of dye conju
98 month efficacy of medical male circumcision (MMC) against herpes simplex virus 2 (HSV-2) incidence am
100 asing coverage of medical male circumcision (MMC) and antiretroviral treatment (ART) at CD4 <350/muL.
101 oexpression called mixed model coexpression (MMC), which models coexpression within a mixed model fra
104 Among males, each 10% increase in community MMC coverage was associated with an adjusted IRR of 0.87
107 ccur as part of the migrating motor complex (MMC), a contractility pattern of the gastrointestinal tr
113 g limbo-keratoplasty with conjunctivoplasty, MMC, and AM transplantation is a promising new surgical
115 tire life and experiencing many copulations (MMC); and polyandrous females with a different male over
117 plus Ag and TLR-induced activation of CTMCs, MMCs, and BMMCs and found that SHIP delays the maturatio
120 dies revealed higher tumor uptake for (64)Cu-MMC(IR800)-TOC than (64)Cu-DA(IR800)-TOC (5.2 +/- 0.2 vs
121 caused a dose-dependent reduction in (64)Cu-MMC(IR800)-TOC uptake whereas (64)Cu-DA(IR800)-TOC was n
124 (range, 0.3-0.5 mg/mL) generated by dividing MMC peak area by internal standard peak area and plottin
126 tm(-/-) single mutant mice survived low-dose MMC similar to wild-type controls, Hus1(neo/neo)Atm(-/-)
128 nuclear core complex proteins, (4) elevated MMC-induced chromosome aberrations, and (5) sensitivity
129 fective HIV prevention strategy is to expand MMC coverage and then scale up ART, but the most cost-ef
132 ommon compounding and storage techniques for MMC resulted in a lower accuracy and wider range of conc
137 and OS were statistically better for RT + FU/MMC versus RT + FU/CDDP (5-year DFS, 67.8% v 57.8%; P =
139 (188 +/- 47 mum, P = 0.285) compared with GS+MMC (109 +/- 26 mum, P = 0.023 to GS) and PS+MMC (48 +/-
140 ng that high ART coverage combined with high MMC coverage provides approximately the same HIV inciden
142 0.0005) from 2.5 (+/-0.3) to 1.2 (+/-0.4) in MMC and from 2.6 (+/-0.2) to 1.4 (+/-0.3) in OLO group,
146 nce after incubation of the DNA-biosensor in MMC solution for a known time was used as indication of
152 rms of cytokine production, we found that in MMCs and BMMCs, which are poor producers of TLR-induced
154 phenotype of constitutive CTMCs and induced MMCs in trachea and large airways in antigen-sensitized
155 in the proximal bronchi, whereas the induced MMCs express only four proteases, mMCP-1, -2, -6, and -7
156 graft was more effective than intraoperative MMC in minimizing pterygium recurrence at the 10-year fo
161 tion in the inter-sample correlation matrix, MMC is able to produce gene coexpressions that are not i
164 (CCR) with fluorouracil (FU) plus mitomycin (MMC) decreased colostomy failure (CF) when compared with
167 across US adults from 2015 to 2030: national MMCs and national F&V price reductions of 10% and 30%.
168 equitable proportional effects.Both national MMCs and price-reduction policies could reduce US CVD mo
170 ents in which multiple copulations occurred, MMC and PMC, had offspring with significantly higher egg
172 dothelial counts after the administration of MMC during surgery, the clinical significance of this fi
173 In rats, intraperitoneal administration of MMC induced PVOD, as demonstrated by pulmonary hypertens
178 ere is good evidence of the effectiveness of MMC when used intraoperatively as prophylaxis against ha
181 vivo studies demonstrating the formation of MMC-DNA adducts, we chose to investigate alternative nuc
186 New findings regarding the penetration of MMC to the endothelium and into the aqueous humor may le
187 stions about the long-term safety profile of MMC, especially with regard to decreased keratocyte and
191 understanding of pathological progression of MMC is mandatory for appropriate treatment to be rendere
193 (MMC) that correlates with delayed repair of MMC-induced chromosomal DNA damage monitored by pulsed-f
194 surveyed in this report support the role of MMC as an adjunctive treatment in surface ablation proce
198 here, this would support further scale-up of MMC and ART for HIV prevention in sub-Saharan Africa.
201 Thus, the T-cell-dependent induction of MMCs in trachea, large bronchi, and small intestine prov
202 rrent topical application of either AgNPs or MMC was performed on 14 pigmented Dutch Belted rabbits.
206 welve of 47 patients (25.5%) in the original MMC group and 2 of 29 patients (6.9%) in the LCAU group
210 or differences in baseline diets, CVD rates, MMC coverage, MMC duration, and declining effects over t
212 us ortholog of CCNO also resulted in reduced MMC and centriole numbers in embryonic epidermal cells.
213 inking an inherited human disease to reduced MMC generation due to a defect in centriole amplificatio
216 er, our data indicate that TGF-beta1 rescues MMC from serum deprivation-induced apoptosis via inducti
217 Due to a lack of evidence for significant MMC activation in the nucleus and for in vivo studies de
219 tment strategies including NSAIDs, steroids, MMC and corneal transplants have shown tremendous succes
220 /neo)Atm(-/-) double mutants showed striking MMC hypersensitivity, consistent with a model in which M
221 ial cell adhesion molecule (EpCAM) targeting MMC-immunoconjugate was prepared and dual-labeled with (
222 rrosive nature, the Mg(CB11H12)2/tetraglyme (MMC/G4) electrolyte system permits standardized methods
225 of adult offspring were higher for PMC than MMC females, showing that polyandrous mating enhances th
227 l-shift and binding assays demonstrated that MMC rapidly decreased the transcript levels of 18S ribos
229 ll proliferation and apoptosis revealed that MMC treatment caused severe damage in highly replicating
231 ngs and gastrointestinal motility during the MMC is largely unknown, however, as is its ability to st
233 C-induced DSBs, but is not released from the MMC-induced DNA lesions, resulting in a defect in homolo
236 ar blebs without oozing were recorded in the MMC group and 2 (10%) in the OLO group, without intergro
237 an ECD was 2,39 2 +/- 342 cells/mm(2) in the MMC group and 2,390 +/- 388 cells/mm(2) in the LCAU grou
239 ent study, 76 of the 114 patients (47 in the MMC group, 29 in the LCAU group) were contacted, whereas
244 s is warranted as well as application of the MMC dual labeling approach with other monoclonal antibod
245 d receptor pharmacology and suggest that the MMC scaffold is a useful tool for the development of dua
246 aline phosphatase was then conjugated to the MMC surface through biotin-streptavidin interactions.
254 Their lymphoblasts were hypersensitive to MMC and MMC-induced monoubiquitination of FANCD2 was imp
258 e role of the 9-1-1 complex in responding to MMC was partially ATR-independent, as a HUS1 mutant that
262 patients treated consecutively with topical MMC (0.4 mg/mL), interferon alpha-2b (1 million units/mL
266 ensitivity, consistent with a model in which MMC exposure in the context of Hus1 dysfunction results
267 both groups at 24 months: 38.4 +/- 7.6% with MMC and 56.2 +/- 7.9% with CM (mean +/- standard error,
268 population soon after surface ablation with MMC, with a decrease in the stromal bed compensated init
270 , and 1,102 healthy women, was analyzed with MMC algorithm and cross validation to identify an optima
271 tric trabeculectomy technique augmented with MMC is an effective procedure in the management of glauc
277 tion, same-site trabeculectomy revision with MMC should be considered as a viable option to achieve r
279 d in patients undergoing trabeculectomy with MMC and in those undergoing Baerveldt implantation durin
280 Tube-shunt surgery and trabeculectomy with MMC are both viable surgical options for managing glauco
282 laucoma medications than trabeculectomy with MMC during the first 2 years of the study, but medical t
286 h tube-shunt surgery and trabeculectomy with MMC produced intraocular pressure (IOP) reduction to the
287 were more frequent after trabeculectomy with MMC relative to tube-shunt surgery, but both procedures
294 ompared with previous topical treatment with MMC (with or without surgery; 29.6 +/- 4.7 months; P = .
296 iversal Hugoniot of fluid metals (UHFM) with MMC at sufficiently extreme pressures and temperatures.
297 riod, stratified by age, sex, and race.A 1-y MMC in 2015 would increase the average national F&V cons
299 25,800 (95% UI 24,300-28,500) DPPs for a 1-y MMC, or the approximately 31,000 (95% UI 26,800-35,300)
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