ライフサイエンスコーパス: MOCA

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1 MOCA accumulates during neuronal differentiation, and it

2 MOCA can also be used in terrestrial settings for on-sit

3 MOCA can use the perchlorate present in the Martian soil

4 MOCA colocalizes with N-cadherin and actin in areas of c

5 MOCA increases the accumulation of adherens junction pro

6 MOCA is associated with Alzheimer's disease tangles and

7 MOCA is designed as a small, lightweight, low-power inst

8 en associated with gamma-secretase activity, MOCA may be involved in the regulation of beta-amyloid p

9 Modifier of cell adhesion (MOCA) is a member of the dedicator of cytokinesis 180 fa

10 Modifier of cell adhesion (MOCA) is a presenilin binding protein that functions as

11 e Organization of Combinatorial Alterations (MOCA), to partially address these challenges.

12 e organization of combinatorial alterations (MOCA), we defined a novel biliary vesicle miR-based pane

13 designated the Mars Organic Carbon Analyzer (MOCA).

14 The phenotypic changes caused by MOCA are due to an acceleration in the rate of intracell

15 In contrast, MOCA does not lower the secretion of amyloid precursor-l

16 nd beta-catenin, whereas reducing endogenous MOCA expression lowers cell-cell aggregation and N-cadhe

17 Furthermore, MOCA deficiency causes an alteration in the actin cytosk

18 The dystrophic axons found in MOCA-deficient mice are associated with abnormal aggrega

19 cell adhesion is a downstream consequence of MOCA-directed APP catabolism.

20 The effect of MOCA expression on the secretion of APP and cellular adh

21 ole in APP metabolism and that the effect of MOCA on APP secretion and cell adhesion is a downstream

22 Here we show that the expression of MOCA decreases both APP and amyloid beta-peptide secreti

23 The loss of MOCA in mice leads to axonal degeneration and causes sen

24 Modifier of cell adhesion protein (MOCA; previously called presenilin [PS] binding protein)

25 Through a series of proof-of-concept tests, MOCA is shown to oxidize a variety of low-molecular-weig

26 We conclude that MOCA regulates N-cadherin-mediated cell-cell adhesion an

27 It is concluded that MOCA plays a major role in APP metabolism and that the e

28 These findings demonstrate that MOCA is required for maintaining the functional integrit

29 Here, we report that MOCA modulates cell-cell adhesion and morphology.

30 ed by proteasome inhibitors, suggesting that MOCA directs nascent APP to proteasomes for destruction.

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