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1 MPI already offers superb contrast and extraordinary sen
2 MPI and beta coefficients were significantly increased i
3 MPI appears to be a valid plaque-scoring system that ass
4 MPI assessed by tissue Doppler imaging M-mode is a simpl
5 MPI directly detects the intense magnetization of iron-o
6 MPI however is not related to the estimated neural excit
7 MPI hydrolysates may have potential for use as dietary i
8 MPI is safe, noninvasive and offers superb sensitivity,
9 MPI provided independent prognostic information in a mul
10 MPI uses magnetic nanoparticle contrast agents that are
11 MPI using CZT SPECT cameras and quantitative gated SPECT
12 hology at 6 MPI (P = 0.01), with a HAI at 11 MPI (P = 0.8) similar to that of H. pylori-infected mice
13 developed more severe gastric pathology at 6 MPI (P = 0.01), with a HAI at 11 MPI (P = 0.8) similar t
14 MPI classified as inappropriate, an abnormal MPI failed to predict major adverse cardiac events, alth
15 MPI (n = 51) than in patients with abnormal MPI (1.61 [interquartile range (IQR), 1.33-2.03] vs. 1.2
16 ere were 23 remaining patients with abnormal MPI (16 having moderate to severe perfusion defect size)
22 difficult to compare detection limits across MPI publications we propose guidelines to improve the co
27 n (compared with CICDA) of active CD with an MPI threshold of 24 video intensity (VI) (sensitivity, 9
37 d Clinic Institutional Review Board-approved MPI database, we identified consecutive patients without
44 d heterozygous mutations of PMM2 (PMM2-CDG), MPI (MPI-CDG), ALG3 (ALG3-CDG), ALG12 (ALG12-CDG), DPAGT
46 whole-heart MRCA integration into a 1.5T CMR-MPI/LGE protocol for the detection of functionally signi
47 est probability underwent CMR (including CMR-MPI, MRCA, and LGE) and x-ray invasive coronary angiogra
48 formances of MRCA, CMR-MPI/LGE, and MRCA+CMR-MPI/LGE integration were determined having XA+fractional
50 acy of a comprehensive 1.5-T stress-rest CMR-MPI/LGE protocol at a cost of longer scanning times.
52 uantification of MFR in (13)N-ammonia PET/CT MPI provides a substantial added diagnostic value for de
54 of possible excitation strategies by current MPI hardware that only does sinusoidal drive waveforms a
56 o determine the feasibility of very low dose MPI by exploring the minimal count level in the myocardi
61 st pain who were candidates for stress-first MPI underwent injection of approximately 185 MBq (5 mCi)
65 developed a systems theoretic framework for MPI called x-space MPI, which has already dramatically i
67 iron oxide nanoparticle tracers required for MPI are also used in MRI, and some are already approved
71 ) patients who had CCTA and 32 (16%) who had MPI underwent cardiac catheterization within 1 year.
72 however, mothers who are at risk for having MPI-CDG children and who consume mannose during pregnanc
73 differ in their splice acceptor sites; human MPI is translated into a polyglutamine tract associated
77 f phosphomannose isomerase-deficient CDG-Ib (MPI-CDG) cells and complementation with PMM2 in PMM2-def
78 al disorder of glycosylation (CDG), type Ib (MPI-CDG or CDG-Ib) have mutations in phosphomannose isom
80 y which MPI loss induces p53, and identifies MPI as a novel regulator of p53 and Warburg metabolism.
81 76; boys without konzo p=0.0224) and KABC-II MPI performance at 2-year follow-up and 4-year follow-up
82 4-year follow-up, the difference in KABC-II MPI score between boys or girls with or without konzo wa
84 demonstrate that Magnetic Particle Imaging (MPI) enables monitoring of cellular grafts with high con
88 ng method, called Magnetic Particle Imaging (MPI), to replace X-ray and CT iodinated angiography, esp
89 mography (PET) myocardial perfusion imaging (MPI) and the improved classification of risk in a large
90 CTA) and SPECT myocardial perfusion imaging (MPI) are complementary imaging techniques to assess coro
91 ne stress-rest myocardial perfusion imaging (MPI) by (99m)Tc-tetrofosmin CZT SPECT and (13)N-ammonia
92 forming stress myocardial perfusion imaging (MPI) for intermediate- to high-risk patients presenting
94 ng rest-stress myocardial perfusion imaging (MPI) in the evaluation of acute low-risk chest pain.
95 esonance (CMR) myocardial perfusion imaging (MPI) is a state-of-the-art noninvasive modality for dete
97 mography (PET) myocardial perfusion imaging (MPI) offers technical benefits compared with single phot
98 Radionuclide myocardial perfusion imaging (MPI) plays a vital role in the evaluation and management
99 t (82)Rubidium myocardial perfusion imaging (MPI) positron emission tomography (PET) and CAC scan.
100 Although SPECT myocardial perfusion imaging (MPI) provides valuable information about patients with c
101 icle for SPECT myocardial perfusion imaging (MPI) quantification often requires manual adjustment, wh
102 CT, to acquire myocardial perfusion imaging (MPI) studies in a quarter of the time (12 s/view) of the
103 graphy (SPECT) myocardial perfusion imaging (MPI) underwent a comprehensive cardiac computed tomograp
104 he accuracy of myocardial perfusion imaging (MPI) using cadmium-zinc-telluride (CZT) SPECT cameras fo
105 ection (AC) of myocardial perfusion imaging (MPI) with a virtual unenhanced cardiac CT scan synthesiz
106 Hybrid PET myocardial perfusion imaging (MPI) with CT allows the incorporation of coronary artery
107 an adjunct to myocardial perfusion imaging (MPI) with SPECT for cardiac risk stratification before n
109 eria (AUC) for myocardial perfusion imaging (MPI) with SPECT on the estimated lifetime attributable r
110 mography (PET) myocardial perfusion imaging (MPI) with Tc-99m single-photon emission computed tomogra
111 ostic value of myocardial perfusion imaging (MPI) with the cadmium-zinc-telluride (CZT) SPECT camera
112 graphy (SPECT)-myocardial perfusion imaging (MPI), a technique that is a mainstay of risk assessment
113 oses for SPECT myocardial perfusion imaging (MPI), but the exact limits for lowering doses have not b
126 al value as part of a CMR protocol including MPI and late gadolinium enhancement (LGE) is not well es
127 n of L1 expression correlates with increased MPI defects, FOA, oocyte aneuploidy, and embryonic letha
128 filling (E/A), myocardial performance index (MPI) and aortic stiffness (pulse wave velocity; PWV) wer
130 index termed the microvessel pericyte index (MPI), a measure of permeability in the blood-brain barri
131 aims to develop a new marginal plaque index (MPI) and to assess its validity and treatment sensitivit
132 t the Global Multidimensional Poverty Index (MPI) at a finest spatial granularity and coverage of 552
133 =0.0424) and on the Mental Processing Index (MPI; p=0.0111) assessments at 2-year follow-up, but girl
135 electrical hearing, multipulse integration (MPI) describes the rate at which detection threshold dec
136 ves to determine the maximum peak intensity (MPI) and wash-in slope coefficient (beta) and evaluated
137 MbFe(IV)O by a myofibrillar protein isolate (MPI) from pork resulted in kMPI=2.2 +/- 0.1 x 10(4)M(-1)
138 g hydrolysis of bovine milk protein isolate (MPI) with Neutrase 0.8L, yielding 15 hydrolysates (H1-H1
139 physical stability of milk protein isolate (MPI)-carbohydrate nutritional beverages containing 8.5%
140 ciated role for Mannose phosphate isomerase (MPI) as a metabolic enzyme required to maintain Warburg
141 have mutations in phosphomannose isomerase (MPI) that impair glycosylation and lead to stunted growt
142 om glucose through phosphomannose isomerase (MPI, Fru-6-P <--> Man-6-P) whose deficiency causes a con
148 erozygous mutations of PMM2 (PMM2-CDG), MPI (MPI-CDG), ALG3 (ALG3-CDG), ALG12 (ALG12-CDG), DPAGT1 (DP
153 one third of those with events had a normal MPI, indicating a need for improved risk stratification.
156 MPR index was higher in patients with normal MPI (n = 51) than in patients with abnormal MPI (1.61 [i
160 , negative predictive value, and accuracy of MPI for detecting significant CAD were 79%, 80%, 91%, 59
163 o determine whether the combined analysis of MPI and CAC could improve the diagnostic accuracy of PET
171 (AC) improved the diagnostic performance of MPI, using coronary angiography as a reference standard.
177 death, increased with increasing tertile of MPI, being approximately 3 times as high for the third t
178 d 2000s, concerns about inappropriate use of MPI and imaging-related radiation exposure increased.
179 tudy was to evaluate the prognostic value of MPI performed with a CZT SPECT camera in a large cohort
180 tent with a key role for the Cys residues on MPI as targets for haem protein-mediated oxidation.
181 vements include a new workflow optimization, MPI-parallelization and fast backbone angle sampling bas
182 characterize magnetic particles and optimize MPI drive waveforms for in vitro biosensing and in vivo
183 uated the added diagnostic value of MFR over MPI alone as assessed with (13)N-ammonia and PET/CT to p
186 could improve the diagnostic accuracy of PET MPI in detection of obstructive coronary artery disease
187 ent and severity of ischemia and scar on PET MPI provided powerful and incremental risk estimates of
188 In a meta-analysis of 11,862 patients, PET MPI demonstrated a higher sensitivity for coronary arter
189 y) without prior CAD, referred to (82)Rb PET MPI followed by invasive coronary angiography performed
193 atment sensitivity was observed for proximal MPI measures in study 1, whereas study 2 showed largest
195 erwent clinically indicated (99m)Tc-setamibi MPI were categorized into appropriate/uncertain (n = 823
196 timulus level function would predict shallow MPI since the amount of current reduction necessary to c
200 s theoretic framework for MPI called x-space MPI, which has already dramatically improved the speed a
204 Conversely, in patients with abnormal SPECT MPI findings, a CACS of 1,314 or more confers an added v
207 Integrated analysis of cardiac CTA and SPECT MPI using the SMARTVis system results in an improved dia
208 ic patients who underwent both CTA and SPECT MPI within a 90-d period were included in our study; 7 o
212 agnostic value of a software-based CTA/SPECT MPI image fusion system over conventional side-by-side a
213 on of absolute MBF index values by CZT SPECT MPI with (99m)Tc-tetrofosmin is technically feasible, al
215 117 studies, including 108 evaluating SPECT MPI, 4 evaluating PET MPI, and 5 evaluating both modalit
216 d rest (5 min; 1,024 +/- 153 MBq) fast SPECT MPI attenuation corrected (AC) by CT and same-day corona
217 d rest (5 min; 1,024 +/- 153 MBq) fast SPECT MPI attenuation corrected (AC) by CT and same-day corona
218 ecutive patients who were referred for SPECT MPI for preoperative cardiac risk assessment before elec
220 cal effects of low-dose radiation from SPECT MPI, we measured the activation of the DNA damage respon
221 mography myocardial perfusion imaging (SPECT MPI) has improved the diagnosis and risk stratification
224 ts and the minimum acquisition time in SPECT MPI using an IQ SPECT protocol, while preserving diagnos
228 egration and combined visualization of SPECT MPI and CTA data may facilitate correlation of myocardia
229 The levels of clinical agreement of SPECT MPI corrected with standard versus virtual unenhanced CT
231 sitivity and specificity of PET and/or SPECT MPI with coronary angiography as the reference standard
234 rpiridaz F 18 was safe and superior to SPECT MPI for image quality, interpretative certainty, and ove
235 -photon emission computed tomography (SPECT) MPI with regard to image quality, interpretative certain
236 photon emission computed tomography (SPECT) MPI, but there has been no systematic comparison of thei
237 Notably, the frequency of abnormal SPECT-MPI is now very low among exercising patients without ty
238 omputed tomography perfusion (CTP) and SPECT-MPI, but the value of resting CTP (rCTP) in acute chest
240 ninferior discriminatory value to CCTA/SPECT-MPI (area under the curve, 0.88 versus 0.90; P=0.64) usi
242 ified on the basis of the 2009 AUC for SPECT-MPI into an appropriate or uncertain appropriateness gro
243 mography-myocardial perfusion imaging (SPECT-MPI) has high predictive value for acute coronary syndro
244 performed for appropriate indications, SPECT-MPI continues to demonstrate high prognostic value.
245 Similarly, the prevalence of ischemic SPECT-MPI declined, from 29.6% to 5.0% (p < 0.001), as did the
249 nt predictor of myocardial ischemia on SPECT-MPI in the presence of stenosis (>/=50% on CTA), with a
250 a subgroup undergoing late rest/stress SPECT-MPI (n=81), CCTA/rCTP had noninferior discriminatory val
251 and compared early rCTP to late stress SPECT-MPI in patients with CAD presenting with suspicion of AC
253 ly than exercise to be associated with SPECT-MPI abnormality (odds ratio: 1.43, 95% confidence interv
255 e compute system using the industry-standard MPI protocol, and no specialised hardware is required.
261 -sestamibi exercise or adenosine rest-stress MPI for clinical indications using a cadmium-zinc-tellur
262 y and specificity of PET versus SPECT stress MPI for >/=50% stenosis of any epicardial coronary arter
263 years; 55% female) who had undergone stress MPI for syncope; 659 patients (94%) had normal perfusion
264 coronary artery disease who underwent stress MPI between 2006 and 2012 for diagnostic workup of synco
266 e second aim was to test the hypothesis that MPI is related to the slope of the psychometric function
270 value of the cardiac time intervals and the MPI assessed by color tissue Doppler imaging M-mode thro
276 Blocking of the protein thiol groups on the MPI by N-ethylmaleimide (NEM) markedly reduced this rate
277 esses of some plant extracts relative to the MPI thiol concentration should afford significant protec
278 el version is implemented in ANSI C with the MPI library (a standardized and portable parallel enviro
279 The added value of MFR as an adjunct to MPI for predicting CAD (luminal narrowing >/= 50%) was e
280 study suggested that AC should be applied to MPI to improve the diagnosis of CAD, especially the spec
281 a cutoff of less than 2.0 for global MFR to MPI findings improved the values to 96% (P < 0.005), 80%
283 s and radiation doses of patients undergoing MPI on an HE-SPECT camera using an ultra-low-dose stress
284 suspected coronary artery disease underwent MPI using a CZT SPECT camera, as well as cine and delaye
285 ltaneously, we demonstrate the first untuned MPI spectrometer/relaxometer with unprecedented 400 kHz
286 eability in the blood-brain barrier, we used MPI in a hybrid physiologically-based pharmacokinetic (P
291 ose directly from exogenous mannose, whereas MPI-deficient CDG fibroblasts with reduced glucose flux
292 work provides mechanistic evidence by which MPI loss induces p53, and identifies MPI as a novel regu
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