ライフサイエンスコーパス: MRP-1

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1 MRP-1 binds to both HSP90 and HSP70, although only inhib

2 MRP-1 inhibition as well as knockdown trapped nuclear GS

3 MRP-1 is also expressed in mitochondria, and we have exa

4 e multidrug resistance-associated protein 1 (MRP-1) in Ewing's sarcoma (ES) predicts poor outcome.

5 otein (P-gp), multidrug resistant protein 1 (MRP-1), B-cell lymphoma (BCL-2) and other targets that a

6 n (P-gp) and multidrug-resistance protein-1 (MRP-1) are adenosine triphosphate-binding cassette prote

7 terestingly, multidrug resistance protein-1 (MRP-1) expression, but not MDR-1 (p-glycoprotein), was o

8 Multidrug resistance-associated protein-1 (MRP-1), an active GSSG efflux mechanism, showed 2-fold i

9 g resistance ABC transporters MDR-1 (Pgp-1), MRP-1, and BCRP-1.

10 lated proteins, such as BCRP-1, MGMT, MDR-1, MRP-1 and MRP-3, after TRP-2 transfection.

11 -1; MCT 1 and 2; OAT1; Oatp1; mdr 1a and 1b; MRP 1 and 5; beta-alanine, system L and system y+L amino

12 dentified three chemokines, MCP-1, MCP-3 and MRP-1, which are negatively regulated by BCL-6 in macrop

13 (IIIB) genome, cells overexpressing P-gp and MRP-1 expressed similar amounts of HIV protein.

14 identified a regulatory module activated by MRP-1, a regulator of BETL differentiation and function.

15 uctive infection by P-gp and augmentation by MRP-1 occur predominantly at a preintegration step but a

16 In contrast, MRP-1 was not preferentially found in GEM domains.

17 Proximity ligand assay demonstrated MRP-1 and YB-1 binding.

18 YB-1 and Ape/Ref-1 were responsible for high MRP-1 expression in EOMA.

19 A hyperactive MRP-1 system for GSSG efflux acts as a critical survival

20 Mitochondrial MRP-1 is glycosylated and localized to the outer mitocho

21 The effect of disrupting mitochondrial MRP-1-dependent efflux activity on the cytotoxic effect

22 Disruption of mitochondrial MRP-1-dependent efflux significantly increases the cytot

23 ime, we have demonstrated that mitochondrial MRP-1 is expressed in the outer mitochondrial membrane a

24 ime, we have demonstrated that mitochondrial MRP-1 is expressed in the outer mitochondrial membrane a

25 d by a verapamil-inhibitable, non-MDR-1, non-MRP-1 transporter whose function or expression may be in

26 ibition of HSP90beta decreases expression of MRP-1 in the mitochondria.

27 Inhibition of MRP-1 expression via siRNA was observed to synergistical

28 Selective inhibitors of MRP-1 and P-gp partially reversed the effect of these tr

29 xamined the submitochondrial localization of MRP-1 and investigated the mechanism of MRP-1 transport

30 Localization of MRP-1 to the outer mitochondrial membrane by the chapero

31 The mitochondrial localization of MRP-1 was examined in ES cell lines by differential cent

32 n of MRP-1 and investigated the mechanism of MRP-1 transport and role of this organelle in the respon

33 atic carcinomas through the up-regulation of MRP-1.

34 uch binding enabled the nuclear targeting of MRP-1 in EOMA in a leptomycin-B-sensitive manner.

35 at least 50-fold in CEM cells overexpressing MRP-1, compared with control CEM cells.

36 g a multidrug resistance-associated protein (MRP-1).

37 Thus, MRP-1 regulates DC migration to lymph nodes, apparently

38 Whether MRP-1 is chaperoned by heat shock proteins (HSPs) was in

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