ライフサイエンスコーパス: MRP

1 MRP obtained by ultrasound exhibited 1,1-diphenyl-2-picr

2 MRP RNA is an abundant, essential noncoding RNA whose fu

3 MRP-1 binds to both HSP90 and HSP70, although only inhib

4 MRP-1 inhibition as well as knockdown trapped nuclear GS

5 MRP-1 is also expressed in mitochondria, and we have exa

6 MRP-14(-/-) recipients also had significantly more lymph

7 MRP-4 localizes to endocytic compartments and its levels

8 MRP-8/14 in saliva might be a potential diagnostic param

9 MRP-8/14 levels were documented with receiver operating

10 MRPs exhibited low PV, p-anisidine and inhibited the for

11 MRPs showed higher PRS and RP than BHA.

12 e multidrug resistance-associated protein 1 (MRP-1) in Ewing's sarcoma (ES) predicts poor outcome.

13 otein (P-gp), multidrug resistant protein 1 (MRP-1), B-cell lymphoma (BCL-2) and other targets that a

14 Multidrug resistance-associated protein-1 (MRP-1), an active GSSG efflux mechanism, showed 2-fold i

15 g resistance ABC transporters MDR-1 (Pgp-1), MRP-1, and BCRP-1.

16 .2, P<0.001) and myeloid-related protein-14 (MRP-14; odds ratio 3.3, P=0.002).

17 ance (PDR) genes, while P. sojae contains 20 MRP and 49 PDR genes.

18 We observed that MRP-14 and MRP-8/MRP-14 heterodimers (S100A8/A9) are expressed in and sec

19 latelets, purified MRP-14, or purified MRP-8/MRP-14 heterodimers into Mrp14(-)/(-) mice decreased the

20 calgranulin A/calgranulin B oligomer, MRP-8/MRP-14 oligomer) chelates a number of first-row transiti

21 protectin (CP, S100A8/S100A9 oligomer, MRP-8/MRP-14 oligomer) is an abundant host-defense protein tha

22 Here, we show that a mesodermal ABCC (MRP) transporter is necessary for endodermal gut morphog

23 rs of the multidrug resistance protein (ABCC/MRP), and the organic anion-transporting polypeptide pro

24 The active MRP fraction (16.1g/L) completely inhibited the growth o

25 ion of a proteinaceous multi-repeat adhesin (MRP) required for binding to the host plant.

26 ded with the increase (p<0.05) in BI for all MRPs.

27 De novo generation of H2O2 by an MRP fraction, extracted from a ribose/lysine Maillard re

28 We observed that MRP-14 and MRP-8/MRP-14 heterodimers (S100A8/A9) are expressed in a

29 ived MRP-14(-/-) DCs infected with MRP-8 and MRP-14 retroviral vectors showed significantly decreased

30 iated drug efflux and that CFTR channels and MRP pumps utilize similar allosteric mechanisms for coup

31 ice doubly deficient in apolipoprotein E and MRP-8/14 complexes had attenuation in atherosclerotic le

32 Alternatively, combined PRCP(gt/gt) and MRP-14(-/-) mice were protected from wire injury with le

33 methylation levels correlated with hsCRP and MRP 8/14 levels and with apnea-hypopnea index (AHI), BMI

34 rgy barrier to both CFTR channel opening and MRP-mediated drug efflux and that CFTR channels and MRP

35 s of the human endoribonucleases RNase P and MRP.

36 the function and organization of RNase P and MRP.

37 Augmented import of RNase P, 5S rRNA, and MRP RNAs depended on PNPASE expression and PNPASE-import

38 Myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) are members of the S100 family of calciu

39 myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) form MRP-8/14 heterodimers (S100A8/A9, c

40 han RNase P, via interactions with Snm1p and MRP RNA.

41 uated vascular inflammation in wild-type and MRP-14-deficient (MRP-14(-/-)) mice that lack MRP-8/14 c

42 art and B6 recipients) in wild-type (WT) and MRP-14(-/-) recipients.

43 Consumption of the assayed MRPs did not affect the hepatic antioxidant defence whil

44 led these TAM bodies for temporal asymmetric MRP bodies.

45 The average MRP concentration in summer exceeds that winter by facto

46 ely to the prevention of cAMP efflux because MRP inactivation is also associated with reduced cAMP de

47 The negative correlations between MRP and DO is marked (r = -0.89).

48 significant associations were found between MRP inhibitor exposure and abnormal protein, glucose, or

49 Associations were observed between MRP inhibitor exposure and eGFR declines of >10 mL/min (

50 et (containing negligible amounts of biscuit MRP).

51 Therefore, the biscuit MRP functional claims could be demonstrated by an in viv

52 purified MRP-14 into mice deficient for both MRP-14 and CD36 failed to reduce carotid occlusion times

53 nitoring the concentration of free and bound MRPs in low lactose milk during shelf life.

54 nzyme reduced the formation of protein-bound MRPs down to 79% after six days at 37 degrees C.

55 identified a regulatory module activated by MRP-1, a regulator of BETL differentiation and function.

56 kat and Raji cell lines expressed comparable MRP and OATP/SLCO (organic anion-transporting polypeptid

57 d, and then analyzed for acrylamide content, MRPs absorbance, pH, color, antioxidant capacity, antiba

58 Control ATPase-defective MRP mutants could not be rescued by this mechanism.

59 lammation in wild-type and MRP-14-deficient (MRP-14(-/-)) mice that lack MRP-8/14 complexes with expe

60 Proximity ligand assay demonstrated MRP-1 and YB-1 binding.

61 Bone marrow-derived MRP-14(-/-) DCs infected with MRP-8 and MRP-14 retrovira

62 ter injury, indicating that platelet-derived MRP-14 directly regulates thrombosis.

63 Results showed that dietary MRP reduced the food efficiency, increased the antioxida

64 onserved with the thermodynamically distinct MRPs.

65 xpressed from four Drosophila genes, Dscam1, MRP, Mhc, and Rdl.

66 and, despite little sequence homology, each MRP subunit exhibits the same "Whirly" transcription-fac

67 ed MRP loci loses this activity, and ectopic MRP RNA expression restores cleavage activity.

68 e RNP isolated from cells with CRISPR-edited MRP loci loses this activity, and ectopic MRP RNA expres

69 f import and assembly of the nucleus-encoded MRPs into ribosomes.

70 e-mediated knockdown of the endoribonuclease MRP did not result in a clear defect in ITS1 processing.

71 (cells per lymph node: 23.7+/-0.7x10(5) for MRP-14(-/-) versus 6.0+/-0.2x10(5) for WT; P<0.0001).

72 Mutations in the genomic locus for MRP RNA cause pleiotropic human diseases, including cart

73 times, indicating that CD36 is required for MRP-14-dependent thrombosis.

74 y artery disease; however, a causal role for MRP-14 in acute coronary syndromes has not been establis

75 ndicating a previously unrecognized role for MRP-14 in immune cell biology.

76 in (MRP)-8 (S100A8) and MRP-14 (S100A9) form MRP-8/14 heterodimers (S100A8/A9, calprotectin) that reg

77 indicating that these cells lack functional MRPs at the plasma membrane.

78 Three hundred twenty-one patients had MRP inhibitor exposure, ranging from 0.02 to 120 mean DD

79 YB-1 and Ape/Ref-1 were responsible for high MRP-1 expression in EOMA.

80 ments that are defined by small volume, high MRP activity, limited PDE activity, and limited exchange

81 t the mito-specific extensions in homologous MRPs generally are involved in inter-MRP contacts and in

82 o-specific MRPs and extensions of homologous MRPs are situated on the peripheral regions, they also c

83 However, MRP-4 is also present in oocytes and early embryos, and

84 nome editing to disrupt the endogenous human MRP RNA locus, thereby attaining what has eluded RNAi an

85 A hyperactive MRP-1 system for GSSG efflux acts as a critical survival

86 nts with acute coronary syndromes identified MRP-14 as a novel predictor of myocardial infarction.

87 to reduced degradation by PDEs and identify MRP-dependent transport mechanisms as novel regulators o

88 orthern blots, and RNA sequencing-implicates MRP RNA in pre-rRNA processing.

89 survival averaged 5.9+/-2.9 weeks (n=10) in MRP-14(-/-) recipients compared with >12 weeks (n=15; P<

90 o weeks after transplantation, allografts in MRP-14(-/-) recipients had significantly higher parenchy

91 Compared with WT recipients, allografts in MRP-14(-/-) recipients had significantly increased T-cel

92 d dry-heating time, TOTOX values of SDASO in MRP-derived microcapsules were 29-87% lower than that of

93 ific amino acid extensions and insertions in MRPs that are homologous to bacterial ribosomal proteins

94 lipid body (LB)-associated proteins included MRP-14, potentially involved in arachidonate transport,

95 Compared with healthy individuals, MRP-8/14 levels were significantly higher in both the sa

96 ity at concentrations widely used to inhibit MRPs.

97 After femoral artery wire injury, MRP-14(-/-) mice had significant reductions in leukocyte

98 Instead, MRP concentrations significantly increase with increasin

99 ologous MRPs generally are involved in inter-MRP contacts and in contacts with mito-specific MRPs, su

100 R indicated the predominance of intermediate MRPs, such as the Schiff base compounds.

101 g reporter gene transiently transfected into MRP-poor MCF7/WT cells, we verified that the LNO(2) mixt

102 sediments at a different fraction from known MRP RNA-containing complexes, the MRP ribonucleoprotein

103 RP-14-deficient (MRP-14(-/-)) mice that lack MRP-8/14 complexes with experimental arterial injury, va

104 t rejection using MRP-14(-/-) mice that lack MRP-8/14 complexes.

105 ing gain of function (GOF) mutants of a long MRP in yeast (Ycf1p cadmium transporter), a short yeast

106 Home cooking conditions leading to low MRP generation and pleasant colours were obtained and co

107 Boiling in water caused very low MRP formation.

108 S100 calcium-modulated protein family member MRP-14 (also known as S100A9) is elevated in platelets f

109 Mitochondrial MRP-1 is glycosylated and localized to the outer mitocho

110 The effect of disrupting mitochondrial MRP-1-dependent efflux activity on the cytotoxic effect

111 Disruption of mitochondrial MRP-1-dependent efflux significantly increases the cytot

112 ime, we have demonstrated that mitochondrial MRP-1 is expressed in the outer mitochondrial membrane a

113 ime, we have demonstrated that mitochondrial MRP-1 is expressed in the outer mitochondrial membrane a

114 The presence of model MRPs in the diet, especially melanoidins, led to a signi

115 se, asparagine and chitosan mixture had more MRPs compared to other mixtures.

116 signaling predict that selective ablation of MRP-dependent cAMP efflux per se does not affect bulk cy

117 The absence of MRP-14 markedly increased T-cell activation and exacerba

118 in some cells because of the accumulation of MRP-4 in lysosomes rather than the loss of CUP-5 per se.

119 water); HT-B diet (containing high amount of MRP derived from biscuits) and LT-B diet (containing neg

120 ean cumulative defined daily doses (DDDs) of MRP inhibitors (NSAIDs, PDE5-i, salicylates, dipyridamol

121 nd serum were collected for the detection of MRP-8/14 and calcium levels.

122 These findings suggest that the effects of MRP inactivation on intracellular cAMP levels reported p

123 The effects of MRP inhibitors on the estimated glomerular filtration ra

124 RNAi and RNase H experiments: elimination of MRP RNA in the majority of cells.

125 ibition of HSP90beta decreases expression of MRP-1 in the mitochondria.

126 demonstrated that elevated plasma levels of MRP-8/14 heterodimer predict increased risk of first and

127 Plasma levels of MRP-8/14 heterodimer were higher in STEMI patients (17.0

128 ecreted MRP, with an altered localization of MRP observed in an ECA3265 mutant background.

129 xamined the submitochondrial localization of MRP-1 and investigated the mechanism of MRP-1 transport

130 Localization of MRP-1 to the outer mitochondrial membrane by the chapero

131 The mitochondrial localization of MRP-1 was examined in ES cell lines by differential cent

132 Moreover, genetic manipulation of MRP expression results in concomitant changes in PDE act

133 n of MRP-1 and investigated the mechanism of MRP-1 transport and role of this organelle in the respon

134 rRNA imbalance is achieved through rescue of MRP RNA levels by ectopic expression.

135 ory mediator, the pathophysiological role of MRP-8/14 complexes in cardiovascular disease is incomple

136 This study investigated the role of MRP-8/14 in cardiac allograft rejection using MRP-14(-/-

137 uch binding enabled the nuclear targeting of MRP-1 in EOMA in a leptomycin-B-sensitive manner.

138 n must be paid to the overall consumption of MRPs from different sources in a conventional diet, due

139 ltrasound treatment resulted in formation of MRPs with all tested carbohydrates.

140 armacological and/or genetic inactivation of MRPs has been shown to augment intracellular cAMP signal

141 V and inhibition of TBARS similar to that of MRPs.

142 gomer, calgranulin A/calgranulin B oligomer, MRP-8/MRP-14 oligomer) chelates a number of first-row tr

143 an calprotectin (CP, S100A8/S100A9 oligomer, MRP-8/MRP-14 oligomer) is an abundant host-defense prote

144 With DPPH, only MRPs at 121 degrees C exhibited higher AA than BHA.

145 factors affecting the molybdate reactive P (MRP) in these waters were analyzed using the data of the

146 r evidence of a conserved eukaryotic RNase P/MRP architecture and provide a strong basis for studies

147 versally found in all enzymes of the RNase P/MRP family, as well as with a phylogenetically conserved

148 ion of the eukaryotic enzymes of the RNase P/MRP family.

149 revisiae RNase MRP in a complex with RNase P/MRP proteins Pop6 and Pop7 solved to 2.7 A.

150 xisting data for the yeast and human RNase P/MRP systems enables confident identification of Pop1p, P

151 rotein-binding domain in the RNAs of RNase P/MRP.

152 ganization of the P3 RNA domains in RNases P/MRP and possible functions of the P3 domains and protein

153 ally distinct RNPs, telomerase, and RNases P/MRP from unrelated progenitor RNAs.

154 The eukaryotic RNases P/MRP have acquired an essential helix-loop-helix protein-

155 pe, in other words mutation rate plasticity (MRP), can be caused by stress or ageing.

156 pathway of thrombosis that involves platelet MRP-14 and CD36 and suggest that targeting MRP-14 has po

157 observation.The movement-related potential (MRP), investigated as intracortical low-frequency LFP ac

158 reactions with allo-endothelial cell-primed MRP-14(-/-) DCs resulted in significantly higher antigen

159 Ovalbumin-primed MRP-14(-/-) DCs augmented proliferation of OT-II (ovalbu

160 RNase mitochondrial RNA processing (MRP) is an essential ribonucleoprotein endoribonuclease

161 RNase mitochondrial RNA processing (MRP) is an essential, evolutionarily conserved endoribon

162 PNC components mitochondrial RNA-processing (MRP) RNA, pyrimidine tract-binding protein (PTB), and CU

163 hip between increased prooxidant production, MRPs, and HCV has not been investigated.

164 he generation of Maillard reaction products (MRP) in beef was investigated.

165 e anti-oxidative Maillard reaction products (MRP) which was used to encapsulate stearidonic acid soyb

166 n acrylamide and Maillard reaction products (MRPs) (>52.6%), respectively.

167 otic activity of Maillard reaction products (MRPs) derived from biscuits were investigated in Wistar

168 ommonly consumed Maillard reaction products (MRPs) from the glucose-lysine system.

169 of protein bound Maillard reaction products (MRPs) is still a challenge in food chemistry.

170 Maillard reaction products (MRPs) show antimicrobial activity that is at least parti

171 ls and poorer in Maillard reaction products (MRPs) than were GPE200 extracts.

172 Formation of Maillard reaction products (MRPs) was monitored by mass spectrometry, spectrophotome

173 ing capacity and Maillard reaction products (MRPs) were determined in ginger cakes after storage and

174 al properties of Maillard reaction products (MRPs) were investigated in a food model system.

175 Maillard reaction products (MRPs) were prepared from aqueous ribose-lysine (RL) and

176 The effect of Maillard reaction products (MRPs), formed during the production of dark malts, on th

177 the formation of Maillard reaction products (MRPs), protein hydrolysates and glycated compounds.

178 in colour of the Maillard reaction products (MRPs), were recorded.

179 formation of the Maillard reaction products (MRPs).

180 and multidrug-resistance-associated protein (MRP) 2 and 3 eliminate toxic compounds from tissues and

181 man multidrug-resistance associated protein (MRP) 2, and Mrp2 knockout mice displayed increased vinor

182 n a multidrug resistance-associated protein (MRP) ATP-binding cassette (ABC) transporter that is expr

183 and multidrug resistance-associated protein (MRP) families.

184 22 multidrug resistance-associated protein (MRP) genes and 49 pleiotropic drug resistance (PDR) gene

185 ant multidrug resistance-associated protein (MRP) subfamily ATP-binding cassette transporters are abl

186 ses multidrug resistance-associated protein (MRP)-overexpressing teniposide-resistant T-cell lymphoma

187 of multidrug resistance-associated protein (MRP)4 (ABCC4) in their luminal efflux in the kidney.

188 findings; hsCRP and myeloid-related protein (MRP) 8/14 levels were also assayed.

189 role of S100A8/A9 [myeloid-related protein (MRP) 8/14, calprotectin] in promoting glomerulonephritis

190 Myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) are members of the S

191 um-binding proteins myeloid-related protein (MRP)-8 (S100A8) and MRP-14 (S100A9) form MRP-8/14 hetero

192 ate calcium-binding myeloid-related protein (MRP)-8/14 in the saliva and serum of individuals with pe

193 The alarmins myeloid-related protein (MRP)8 and MRP14 are the most prevalent cytoplasmic prote

194 Multidrug resistance protein (MRP)-4 localizes to the gut granule membrane, consistent

195 identified mitochondrial ribosomal protein (MRP)L14 as the specific interacting protein partner of C

196 P], multidrug resistance-associated protein [MRP] 2) were unchanged at messenger RNA or protein level

197 he multidrug resistance-associated proteins (MRPs/ABCC) are responsible for this GSH release.

198 Myeloid-related proteins (MRPs) 8 and 14 are cytosolic proteins secreted from myel

199 metabolites, multidrug-resistance proteins (MRPs) extrude the second-messenger cAMP from various cel

200 tentials, and multidrug resistance proteins (MRPs) MRP4 and MRP5 contribute to cyclic nucleotide effl

201 xporters (the multidrug resistance proteins (MRPs)) and a unique ATP-gated ion channel (cystic fibros

202 ong and short multidrug resistance proteins (MRPs), and an ATP-gated anion channel, the cystic fibros

203 regulation of multidrug resistance proteins (MRPs).

204 genome and mitochondrial ribosomal proteins (MRPs) that are encoded by nuclear genes and imported int

205 ge mass of mitochondrial ribosomal proteins (MRPs), including large mito-specific amino acid extensio

206 Several prototypical MRP inhibitors block PDE activity at concentrations wide

207 Furthermore, affinity-purified MRP ribonucleoprotein (RNP) from HeLa cells cleaves the

208 In contrast, infusion of purified MRP-14 into mice deficient for both MRP-14 and CD36 fail

209 f WT platelets, purified MRP-14, or purified MRP-8/MRP-14 heterodimers into Mrp14(-)/(-) mice decreas

210 Infusion of WT platelets, purified MRP-14, or purified MRP-8/MRP-14 heterodimers into Mrp14

211 s II(-/-) hosts and of B6 WT hosts receiving MRP-14(-/-) DCs had significantly augmented inflammatory

212 Ribonuclease MRP is an endonuclease, related to RNase P, which functi

213 A3 and to the RNA component of ribonuclease MRP, which cleaves site A3.

214 RNase MRP has established roles in multiple pathways including

215 RNase MRP is a ribonucleoprotein with a large catalytic RNA mo

216 Ribonuclease P (RNase P) and RNase MRP are closely related ribonucleoprotein enzymes, which

217 ng we show that eukaryotic RNase P and RNase MRP have a modular architecture, where proteins stabiliz

218 The structures of RNase P and RNase MRP have not yet been solved, so it is unclear how the p

219 teins, known components of RNase P and RNase MRP, bind to yeast telomerase RNA and are essential cons

220 reatest difference between RNase P and RNase MRP, highlighting the importance of the adaptation of th

221 trate and the Saccharomyces cerevisiae RNase MRP holoenzyme.

222 A domain from Saccharomyces cerevisiae RNase MRP in a complex with RNase P/MRP proteins Pop6 and Pop7

223 In Saccharomyces cerevisiae, RNase MRP comprises an RNA subunit and ten proteins.

224 s a role for the host endoribonuclease RNase MRP in viral RNA degradation and recombination.

225 ving rise to a closely related enzyme, RNase MRP, which has similar components but has evolved to hav

226 Thus, a role for RNase MRP in human pre-rRNA processing is established.

227 d several new potential substrates for RNase MRP including a cell cycle-regulated transcript, CTS1; t

228 precursors, as well as some mRNAs, for RNase MRP.

229 In addition, we found RNase MRP to be involved in the regulation of the Ty1 transpos

230 o RNase MRP, and demonstrate that four RNase MRP protein components, all shared with RNase P, interac

231 ever, after the initiation of mitosis, RNase MRP localizes throughout the entire nucleus and in a sin

232 To identify novel RNase MRP substrates, we utilized RNA immunoprecipitation and

233 ons for the structural organization of RNase MRP and the roles of its components are discussed.

234 ults reinforce and broaden the role of RNase MRP in cell cycle regulation and help to identify new ro

235 gene, coding for the RNA component of RNase MRP, lead to reduced production of the endoribonucleolyt

236 in eukaryotes: snRNA, snoRNA, RNase P, RNase MRP, Y RNA or telomerase RNA.

237 f interactions between a photoreactive RNase MRP substrate and the Saccharomyces cerevisiae RNase MRP

238 d TBSV RNA, suggesting that in plants, RNase MRP is involved in TBSV RNA degradation.

239 vidual subunits with the P3 arm of the RNase MRP RNA is revealed to be negligible whereas the 1:1 Rpp

240 lly found in daughter cells, where the RNase MRP substrate, CLB2 mRNA, localizes.

241 n of SNM1, encoding a component of the RNase MRP, and a temperature-sensitive mutation in the NME1 ge

242 conserved RNA region that is unique to RNase MRP, and demonstrate that four RNase MRP protein compone

243 umably associating preferentially with RNase MRP, rather than RNase P, via interactions with Snm1p an

244 fy RNA that physically associates with RNase MRP.

245 so show that the highly purified yeast RNase MRP cleaves the TBSV RNA in vitro, resulting in TBSV RNA

246 Ribonuclease (RNase) MRP is a ubiquitous and essential site-specific eukaryot

247 Salivary MRP-8/14 levels correlated significantly with the presen

248 A high diagnostic potential of salivary MRP-8/14 was detected for periodontitis (ROC = 0.86).

249 d that ECA3270 and ECA3271 regulate secreted MRP levels by increasing and decreasing, respectively, t

250 We show that c-di-GMP regulates secreted MRP levels in Pba1043 through the action of two genes en

251 ays an important role in regulating secreted MRP, with an altered localization of MRP observed in an

252 Correlations between salivary and serum MRP-8/14 levels and clinical parameters, bacteria, and c

253 ition to their role in the ribosome, several MRPs have auxiliary functions or have been implicated in

254 Suppressing the homologous soybean MRP gene also generated low-phytic-acid seed, suggesting

255 Although most of the mito-specific MRPs and extensions of homologous MRPs are situated on t

256 55S mitoribosome reveals that mito-specific MRPs of both the SSU and LSU are involved directly in th

257 contacts and in contacts with mito-specific MRPs, suggesting a stepwise evolution of the current arc

258 proteins and an additional 35 mito-specific MRPs.

259 the interesting findings for these specific MRPs, attention must be paid to the overall consumption

260 t MRP-14 and CD36 and suggest that targeting MRP-14 has potential for treating atherothrombotic disor

261 t with their potency in inhibiting PDEs than MRPs.

262 ution localization analyses demonstrate that MRP RNA, CUGBP, and PTB colocalize at the PNC as a retic

263 This study demonstrates that MRP-8/14 broadly regulates vascular inflammation and con

264 Our results indicate that MRP-14 regulates B7 molecule expression and reduces anti

265 sion compared with controls, indicating that MRP-8/14 regulates B7-costimulatory molecule expression.

266 We observed that MRP-14 and MRP-8/MRP-14 heterodimers (S100A8/A9) are exp

267 The MRP concentrations are geographically unrelated to erosi

268 Although the MRP was detected only during dynamic periods of the task

269 TTI-237 was not recognized by the MRP or MXR transporters.

270 from known MRP RNA-containing complexes, the MRP ribonucleoprotein ribozyme and human telomerase reve

271 The genes encoding the MRP and the T1SS are tightly linked to genes encoding se

272 f the legacy P in the sediments explains the MRP concentrations which are most pronounced at low DO c

273 lasma membrane, and these cells exported the MRP substrate calcein.

274 e, and probenecid, supporting a role for the MRP transporters in this process.

275 d substantial information about grasp in the MRP corroborating its suitability for brain-machine inte

276 o the highly basic beta sheet surface of the MRP complex via nonspecific, electrostatic contacts.

277 re subunits in addition to components of the MRP complex.

278 The dendritic cells (DCs) of the MRP-14(-/-) recipients of bm12 hearts expressed signific

279 e protein 4 (MRP4; ABCC4) is a member of the MRP/ATP-binding cassette family serving as a transmembra

280 p35 and Cfd1 are prototypical members of the MRP/Nbp35 class of iron-sulfur (FeS) cluster scaffolds t

281 indings support a working model in which the MRP RNA-protein complex becomes nucleated at the PNC in

282 It was shown that the MRPs derived from electro-activated whey at a concentrat

283 This cytotoxicity could be related to their MRPs content.

284 This MRP is genetically switchable, dependent on the quorum-s

285 Thus, MRPs can be considered as active ingredients for antimic

286 Concomitant incidental exposure to MRP inhibitors and TDF did not result in major additiona

287 Exposure to MRP inhibitors was associated with an additional mean eG

288 her ABC transporter that acts in parallel to MRP-4 for the formation of birefringent material in the

289 identified a mutation in the ABC transporter MRP-4 that rescues the degradation defect and the corres

290 ance-associated protein efflux-transporters (MRPs) in the renal proximal tubule could enhance this un

291 RP-8/14 in cardiac allograft rejection using MRP-14(-/-) mice that lack MRP-8/14 complexes.

292 this type, the Arabidopsis thaliana vacuolar MRP, AtMRP1 (AtABCC1), and its functional equivalent(s)

293 that produces thrombohemorrhagic vasculitis, MRP-14(-/-) mice had significant reductions in neutrophi

294 Whether MRP-1 is chaperoned by heat shock proteins (HSPs) was in

295 Beyond its serving as a risk marker, whether MRP-8/14 participates directly in vascular inflammation

296 Six protein subunits interact directly with MRP RNA and four with pre-rRNA.

297 marrow-derived MRP-14(-/-) DCs infected with MRP-8 and MRP-14 retroviral vectors showed significantly

298 lso rescued defective drug export by a yeast MRP (Yor1p) with ATP binding defects in its NBDs.

299 t (Ycf1p cadmium transporter), a short yeast MRP (Yor1p oligomycin exporter), and human CFTR channels

300 ons rescued ATP binding mutants of the yeast MRPs and CFTR by increasing ATP sensitivity.