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1 MS/MS evaluation of a set of randomly selected 210 metab
2 mparable with what obtained with multiple 1D MS/MS experiments targeted on each individual component
4 , the amount of information obtained with 2D MS was comparable with what obtained with multiple 1D MS
8 vra cells show the highest rhythmicity among MS neurons and fire with short burst duration (median, 3
10 experimental allergic encephalomyelitis (an MS animal model), and the disease suppression depended o
15 S by sex, year of birth, age/vital status at MS diagnosis, and region of residence (county), resultin
16 However, the former requires desalting to be MS-compatible, and the latter requires fraction pooling
17 tructures of the compounds were confirmed by MS, FTIR &(1)H NMR; and their properties were characteri
18 onstrated that covalent labeling followed by MS markedly increased the predictive power of the integr
20 ped using large-scale bottom-up proteomic CE-MS data (5% ( approximately 0.8M) acetic acid as backgro
21 rbon fiber ionization mass spectrometry (CFI-MS), which uses a carbon fiber bundle as the ion source,
24 etection- tandem mass spectrometry (HPLC-DAD-MS/MS) identified 29 phenolics belonging to phenolic aci
25 the first time, this study reports a ddHRMS/MS method capable of complementing existing quantitative
31 -catenin signaling in CNS vessels during EAE/MS partially restores functional BBB integrity and limit
32 er and the SCNPs can be well ionized via ESI MS, and the strong covalent cross-links are stable durin
35 equimolar concentration library, the CaR-ESI-MS assay identified 100% of ligands with affinities >500
40 ectrospray ionization mass spectrometry (ESI-MS) assay and model membranes of defined composition, to
41 ectrospray ionization mass spectrometry (ESI-MS) in native conditions to study the influence of modif
42 ray ionization tandem mass spectrometry (ESI-MS/MS) method has been developed for the identification
43 al (COSY, NOESY, DOSY) NMR spectroscopy, ESI-MS, ion-mobility mass spectrometry (IM-MS), AFM, and TEM
44 ted using the DRILL interface coupled to ESI-MS along with an improved limit of detection (10-fold en
45 betacyanins were identified by HPLC-DAD-ESI/MS(n), 23 and 15 new compounds being described in yellow
48 A quantitative evaluation of the LC-FAIMS-MS method was performed giving limits of detection in th
49 tures detected in human urine using LC-FAIMS-MS was increased approximately threefold compared to LC-
50 romatography and mass spectrometry (LC-FAIMS-MS) is shown to enhance peak capacity for omics applicat
52 s accomplished in blood using time-of-flight MS with perfluoro coated Si-GLAD SALDI, by comparison to
54 nternational diagnostic imaging criteria for MS are not necessarily helpful in distinguishing these t
55 nd therefore could be a treatment option for MS, because it combines features of immunomodulation wit
57 reate internal tryptic peptide standards for MS as well as an intact protein bearing multiple linear
66 Gas Chromatography - Mass Spectrometery (GC-MS) together with (13)C stable isotope-labelled glucose
67 Gas chromatography-mass spectrometry (GC-MS) and liquid chromatography-tandem mass spectrometry (
68 ust gas chromatography-mass spectrometry (GC-MS) method for the simultaneous determination of propane
69 ing gas chromatography mass spectrometry (GC-MS), we identified compounds typically associated with p
70 chromatography-tandem mass spectrometry (GC-MS/MS) for GC-amenable pesticides; (ii) hydrophilic inte
73 mpositions (C, H, N, O, S), Py-GC/FID, Py-GC/MS and SEM imaging reveal extensive degradation of the w
76 on time to the scan duty cycle but generates MS/MS spectra rich in b/y-type and c/z(*)-type product i
77 rategy due to the reproducibility of the gum MS profile, even in the presence of other organic and in
81 en/deuterium exchange mass spectrometry (HDX-MS) in the protein therapeutic field is undisputed; howe
82 en/deuterium-exchange mass spectrometry (HDX-MS) provides detailed insight into the structural dynami
83 en/deuterium exchange mass spectrometry (HDX-MS), fast photochemical oxidation of proteins (FPOP), al
86 romatography-tandem mass spectrometry (HILIC-MS/MS) for polar pesticides, and; (iii) reversed-phase l
89 mprises methanol extraction followed by HPLC-MS analysis, and was able to identify 14 fungus secondar
91 hromatography-tandem mass spectrometry (HPLC-MS/MS) method with multiple reaction monitoring (MRM) mo
92 scular to jugular vein were assessed by HPLC/MS/MS, and retention of the fat depot was monitored by M
97 ded myoglobin analyzed using conventional HX-MS, 97% coverage of the myoglobin sequence was still obt
98 its utility, we applied the correction to HX-MS excipient screening data collected for a pharmaceutic
99 have applied this fragment-based hyphenated MS technology to oligosaccharide standards and to de nov
100 r and I using the MIC method followed by ICP-MS determination were 0.039 and 0.015mugg(-1), respectiv
102 o the development of this method, all LA-ICP-MS analyses of glacier ice involved a single element per
105 s Spectrometry (ICP-MS), single-particle-ICP-MS (sp-ICP-MS), Transmission Electron Microscopy (TEM),
107 ely coupled plasma mass-spectrometry (SP-ICP-MS) was used for the first time with a prototype data ac
108 try (ICP-MS), single-particle-ICP-MS (sp-ICP-MS), Transmission Electron Microscopy (TEM), Analytical
110 tively coupled plasma mass spectrometry (ICP-MS), amino acid analysis, and spectroscopy (ATR-IR, Rama
111 tively Coupled Plasma Mass Spectrometry (ICP-MS), single-particle-ICP-MS (sp-ICP-MS), Transmission El
112 yclotron resonance mass spectrometry (FT-ICR MS) and quantify DOM photochemical activity using probe
114 yclotron Resonance-Mass Spectrometry (FT-ICR-MS), which delivered the molecular formulae and ion inte
115 ting from ion mobility-mass spectrometry (IM-MS) experiments provide a promising orthogonal dimension
121 how smoking affects blood DNA methylation in MS patients, by assaying genome-wide DNA methylation and
124 sition was significantly over-represented in MS compared to control cases in all compartments studied
126 ersity of Notre Dame in South Bend, Indiana (MS), and finally Georgetown University, in Washington, D
127 njection of the HuR small-molecule inhibitor MS-444 in AOM/DSS mice, a model of IBD and inflammatory
139 , and specific binding assessment using a LC-MS/MS "cold tracer" method, we have identified 8 (PF-064
140 ecame the targets in the development of a LC-MS/MS method which underwent a rigorous in-house validat
143 Integration of RNA-seq data from TCGA and LC-MS/MS proteomics from WS revealed an upregulation of ext
145 ADG), rumen fluid metabolomic analysis by LC-MS and multivariate/univariate statistical analysis were
149 total of 2565 proteins was identified by LC-MS/MS analysis (q-value </= 0.01) that accounted for 64%
150 1-dehydrocorticosterone) were measured by LC-MS/MS in maternal and cord plasma from 259 Caucasian wom
153 Variation between this and a conventional LC-MS/MS method using authentic standards for calibration w
154 emcitabine treatment using iTRAQ labeling LC-MS/MS, because it was featured with the advantages of st
155 gh resolution MS (LC-HRMS), LC-tandem MS (LC-MS/MS) and nuclear magnetic resonance (NMR) spectroscopy
159 liquid chromatography-mass spectrometry (LC-MS) and gas chromatography-MS (GC-MS) data relative to l
160 liquid chromatography-mass spectrometry (LC-MS) for biomarker determination using ProGastrin Releasi
161 liquid chromatography-mass spectrometry (LC-MS) method to separate and quantify R- and S-9-PAHSA, an
162 liquid chromatography-mass spectrometry (LC-MS)-based detection of BPDE-N(2)-dG in BaP-treated roden
163 liquid-chromatography-mass spectrometry (LC-MS)-based metabolomics analysis of human biospecimens ha
164 chromatography tandem mass spectrometry (LC-MS/MS) was used for collection, identification, and quan
165 chromatography-tandem mass spectrometry (LC-MS/MS) were used to quantify volatile and ionic PFASs, r
167 chromatography-tandem mass spectrometry (LC-MS/MS), (13)C6-metabolites were radiocalibrated by their
173 eased approximately threefold compared to LC-MS alone due to a combination of the reduction of chemic
176 observed directly in human samples using LC-MS techniques, even though sophisticated methodologies h
178 liquid chromatography-mass spectrometry (LC/MS) techniques to investigate the role of glucose during
180 degrees C for 60min were identified using LC/MS and LC-MS/MS following monodimensional electrophoresi
181 Importantly, we show quantitatively with LC/MS analytics that the intracellular cargo release is con
182 The results were in highly agreement with LC/MS/MS which verified our method is extremely accurate.
185 , endo-beta-galactosidase coupled with MALDI-MS allowed these two epitopes, for the first time, to be
189 g for the investigation of mechanosensitive (MS) ion channels, since they are highly sensitive to the
190 d methodology employed the negative ion mode MS, included 44 authentic whiskies from diverse brands a
192 ffect on labeled proteome analysis by nanoLC-MS(2), and demonstrate proof-of-principle applications o
194 pectrometer, enabling high-resolution native MS analysis of 0.8- to 2.3-MDa prokaryotic 30S, 50S and
195 ffinity constant was determined using native MS, revealing a nearly eightfold enhancement in dimeriza
200 sis whereby the variability in the course of MS is driven by the very same pathogenic mechanisms resp
201 e and was elevated in cerebrospinal fluid of MS patients during relapse compared with specimens acqui
202 We conclude that nuclear localization of MS is a unique feature of respiratory yeasts such as P.
206 1-year increase in age at menarche, risk of MS was reduced by 13% (hazard ratio = 0.87, 95% confiden
207 omarker discovery studies, while the role of MS in translating biomarker candidates to clinical diagn
208 ound for zebrafish (Danio rerio), the use of MS-222 and benzocaine also appears to induce avoidance b
211 bolites were investigated by LC/ESI-Orbitrap-MS in urine and finger nails collected from a Norwegian
212 ctivity underlie cognitive dysfunction in PP-MS, and that CLs possibly play a role in variability and
214 emitting MS [RRMS], 17 secondary progressive MS [SPMS], and 40 primary progressive MS [PPMS]) from C1
217 lic compounds were identified by LC-PDA-QTOF/MS and quantified by UPLC-PDA-FL, as 26 anthocyanins, 9
221 V-1 (AC), 47 HAM/TSP, 74 relapsing-remitting MS [RRMS], 17 secondary progressive MS [SPMS], and 40 pr
224 combination of HPLC-PDA, LC-high resolution MS (LC-HRMS), LC-tandem MS (LC-MS/MS) and nuclear magnet
226 uantitative proteomics using high-resolution MS acquisition on the Orbitrap Elite and Orbitrap Fusion
227 were successfully quantified, and the SALDI-MS results obtained on the desalted serum sample spots s
232 lar clinical features to multiple sclerosis (MS), but the international diagnostic imaging criteria f
233 e demyelinating disorder multiple sclerosis (MS), contributes to axonal dysfunction and neurodegenera
235 2A in an animal model of multiple sclerosis (MS), we administered blocking antibody to CLEC12A that s
240 iquid chromatography (LC)-mass spectrometry (MS) for the determination of their pharmacokinetic prope
241 alytical methods based on mass spectrometry (MS) have been successfully applied in biomarker discover
243 -somatropin); (ii) native mass spectrometry (MS) offered in-depth information, a substitution degree
247 Despite the ubiquity of mass spectrometry (MS), data processing tools can be surprisingly limited.
249 cids, here we used modern mass spectrometry (MS)-based techniques to separate and sequence de novo pr
252 ins lymphoid aggregates, called milky spots (MSs), that contribute to peritoneal immunity by collecti
253 ld be taken out and analyzed by direct spray MS of the biosensor chip to confirm the identity of DON.
255 , LC-high resolution MS (LC-HRMS), LC-tandem MS (LC-MS/MS) and nuclear magnetic resonance (NMR) spect
256 of cold-ion spectroscopy coupled with tandem MS may render this the key technology to unravel complex
258 uantified in rumen and plasma using targeted MS to validate and evaluate the simple combination of me
263 ction of antifungal resistance, although the MS-AFST assay performed at 3 h of the in vitro antifunga
264 that platelets and Meg-01 cells express the MS cation channel Piezo1, which may contribute to Ca(2+)
266 nant analysis (PLSDA), were performed on the MS and Raman spectral data, along with a variety of spec
267 rom either source had the same effect on the MS-CPET rate constants, and a combined Bronsted plot of
268 d for PSI was lower, and the distance to the MS orifice over which spray could be obtained was larger
270 TLC-MS of selected zones, eluted via the TLC-MS Interface into MS, confirmed the identity of coumarin
271 spray ionization (PSI) technique coupled to MS might overcome these steps by direct analysis of comp
272 We propose that targeted delivery of GD1a to MS lesions may act as a potential novel molecular tool t
273 ites, while specificity and NPV of MALDI-TOF MS for males were significantly higher than those for fe
274 demonstrate the value of this new MALDI-TOF MS method as an analytical tool for the identification o
275 S intervention included: real-time MALDI-TOF MS pharmacist notification and prospective AMS provider
276 rption ionization-time of flight (MALDI-TOF) MS organism identification and automated-system-based an
278 e-of-flight mass spectrometry (LAESI-IMS-TOF-MS) was used for the analysis of synthetic polymers and
281 zation time-of-flight mass spectrometry (TOF-MS) allows the detection of thousands of compounds.
288 hat enzyme-free heat treatment prior to UPLC-MS/MS analysis gives better sensitivity and reduces chro
290 id [PCA] and urocanic acid [UCA]) using UPLC-MS/MS, transepidermal water loss (TEWL) and epidermal pH
292 mechanical tunneling, multistructural VTST (MS-VTST), multi-path VTST (MP-VTST), both reaction-path
293 hin the source zone to better assess whether MS can serve as a proxy for monitoring HC contamination
294 DL may reflect core mechanisms through which MS components develop and progress in parallel with insu
296 ive TH1/TH17CM cells expand in patients with MS and promote relapses after bystander recruitment to t
300 matched individually with 10 people without MS by sex, year of birth, age/vital status at MS diagnos
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