ライフサイエンスコーパス: MST

1 MST kinases are emerging as key signaling molecules that

2 MST-312 also inhibited the replication of HSV-2 and a re

3 MST-312 treatment reduced the number of cells displaying

4 MSTd neurons also show significant correlations with per

5 CSE and 3-MST are expressed in the human microvasculature.

6 CSE and 3-MST were expressed in all skin samples.

7 CSE and 3-MST were quantified in forearm skin samples from 5 healt

8 drial H(2)S-producing pathway, governed by 3-MST, complements and balances the bioenergetic role of K

9 SiRNA silencing of 3-MST reduced basal bioenergetic parameters and prevented

10 zyme 3-mercaptopyruvate sulfurtransferase (3-MST) stimulated mitochondrial H(2)S production and enhan

11 and 3-mercaptopyruvate sulfurtransferase (3-MST), in comparison to adjacent lung tissue.

12 and 3-mercaptopyruvate sulphurtransferase (3-MST), which endogenously produce hydrogen sulphide (H2 S

13 Most (70%) MSTd neurons were disparity selective with monotonic tun

14 The core of the pathway consists of a MST and LATS family kinase cascade that ultimately phosp

15 h varying hydrogeological properties using a MST toolbox containing two bacteriophage groups (phage i

16 d, because mammalian Tao-1 similarly affects MST kinases.

17 ly different than the renal transplant alone MST (85 days, p = 0.46), with histopathology documenting

18 c to evaluate the reliability of alternative MST solutions, we discover that they encompass a wide ra

19 hnique to estimate the number of alternative MSTs for a data set and find that multiple MSTs exist fo

20 the number and configurations of alternative MSTs, and allows identification of the most credible MST

21 roximates a multiplicative interaction among MST inputs.

22 hether recurrent, competitive dynamics among MSTd neurons that serve to reduce uncertainty about head

23 Cells are first grouped into clusters and an MST is then constructed to connect cluster centers.

24 s branch point transform chorismate using an MST enzyme.

25 e new "gold standard" approach for analyzing MSTs for molecular epidemiology so that this generally u

26 We find BIBR-1532 (2) and MST-312 (5) inhibit only human telomerase, whereas beta-

27 ms of division location, cleavage angle, and MST distance, as well as fiber orientation and dynamics.

28 al role of these models in dosing of ECT and MST.

29 native to empirical ST titration for ECT and MST.

30 , and frontomedial electrode placements) and MST (round coil on vertex) in nonhuman primates.

31 on of >/=60% protein needs after surgery and MST scores were independent predictors of LOS.

32 al model of primate visual areas V1, MT, and MSTd based on that of Layton, Mingolla, and Browning tha

33 ost proximal to the vestibular periphery and MSTd being most distal.

34 the survival using depleting IgG2a antibody (MST=18) was similar to that using WT FR70.

35 ull hypothesis is rejected and second, apply MST-based tests to these pathways to select those that s

36 ies that exceeded those seen in cortex (area MSTd) under identical conditions.

37 ng) to show that population activity in area MSTd predicts the dependence of heading thresholds on re

38 slation were mostly opposite, unlike in area MSTd where roughly equal proportions of neurons have vis

39 on by recording from neurons in macaque area MSTd that integrate visual and vestibular cues regarding

40 pulation activity of neurons in macaque area MSTd.

41 ex [including medial superior temporal area (MST), fundus of superior temporal area (FST), and dorsal

42 (MT), and the medial-superior temporal area (MST).

43 vision of the medial superior temporal area (MSTd) and the ventral intraparietal area (VIP), have bee

44 corded dorsal medial superior temporal area (MSTd) cortical neuronal responses to the visual motion a

45 umans, dorsal medial superior temporal area (MSTd) has been implicated in heading perception.

46 The dorsal medial superior temporal area (MSTd) in the extrastriate visual cortex is thought to pl

47 tuning in the medial superior temporal area (MSTd) is approximately head centered.

48 ement, dorsal medial superior temporal area (MSTd) neurons represent their current heading direction.

49 nd the dorsal medial superior temporal area (MSTd) of macaques.

50 in the dorsal medial superior temporal area (MSTd) of the macaque visual cortex.

51 t, unlike the medial superior temporal area (MSTd) where optic flow tuning typically dominates or the

52 gions, dorsal medial superior temporal area (MSTd), ventral intraparietal area (VIP), and visual post

53 ), and dorsal medial superior temporal area (MSTd).

54 Similar to areas MSTd and VIP, the population of V6 neurons was best able

55 However, unlike areas MSTd and VIP, V6 neurons are almost universally unrespon

56 Area V6 is interconnected with areas MSTd and VIP, allowing for the possibility that V6 also

57 can induce seizures with E-field as focal as MST, although these electrode and coil configurations af

58 and those predicted by ideal models such as MST.

59 lamblia were detected in sewage, as well as MST markers and resistance genes to aminoglycosides, bet

60 To overcome these issues, a community-based MST method has been developed.

61 These results suggest that a community-based MST method may be another useful tool for determining so

62 e a fecal library to perform community-based MST.

63 target populations required for marker-based MST occur around the globe.

64 Clustering cells before MST construction reduces the complexity of the tree spac

65 lly adjusted models, the interaction between MST status and sex was significant in the 30-day and 1-y

66 Our results support a causal link between MSTd neurons and multisensory heading perception but sug

67 de, consistent with the idea that biological MSTd might be well equipped to efficiently encode variou

68 r length-scaling exponents than predicted by MST due to an evolutionary tradeoff between fire escape

69 The kinetics of H2S production by MST from 3-MP was studied at pH 7.4 in the presence of v

70 transsynaptic networks that are targeted by MST for optimal therapeutic response.

71 dicate that sulphide generated by CSE or CAT/MST or from thiosulphate is unlikely to contribute to O2

72 ase/mercaptopyruvate sulphurtransferase (CAT/MST) pathway caused an increase in HPV similar to that o

73 sue growth and homeostasis through a central MST-LATS kinase cascade.

74 lateral ECT (25%) was comparable to cap coil MST (23%), demonstrating that ECT with a low current amp

75 onducted in North London, England, comparing MST with usual services provided by two youth offending

76 In contrast, MSTd neurons show reference frames between head and eye

77 (MST=18.5 days) and rAAV-K-treated controls (MST=19 days).

78 n-specific phages (detected using a low-cost MST method) in municipal wastewaters (MW) and assesses w

79 The Salvador adaptor protein couples MST kinases to the LATS kinases to form the hippo pathwa

80 d allows identification of the most credible MST or MSTs by using a bootstrapping metric.

81 fter the development of severe renal damage (MST after proteinuria onset was 12.5 weeks versus 4 week

82 om an unplanned change in heading direction, MSTd shifts toward representing the goal location.

83 STN 20 mg/kg nor CsA 20 mg/kg was effective (MST 6 days [n=2] and 7 days [n=5], respectively).

84 versible inhibitor of the telomerase enzyme, MST-312, to investigate telomerase activity during HSV i

85 tion was hampered by variable ratios of FIB, MST markers, and pathogens measured in seawater and in g

86 al predictions from the three models we find MST predictions are most consistent with our observed al

87 ation focality by 40-53% for ECT and 26% for MST, supporting amplitude individualization as a means o

88 major physiological persulfide acceptor for MST.

89 However, although serving as an adaptor for MST and LATS, Salvador can also bind RASSF1A.

90 CT and 37.4% of maximum device amplitude for MST).

91 human and a ruminant-specific qPCR assay for MST in a drinking water source.

92 llows us to propose a detailed mechanism for MST in which an Asp-His-Ser catalytic triad is positione

93 Further investigation into the mechanism for MST-312 is warranted and may provide novel targets for H

94 higher among those who screened positive for MST compared with those who screened negative (30-day: a

95 Positive response to screen for MST administered in VHA facilities.

96 A positive screen for MST was independently associated with postdeployment hom

97 A positive screen for MST was significantly and independently associated with

98 Among veterans with a positive screen for MST, rates of homelessness were 1.6% within 30 days, 4.4

99 sness among males with a positive screen for MST.

100 Moreover, our data from MST analysis have pointed to positive binding cooperativ

101 sistent with a mixture of contributions from MSTd and other areas with vestibular-dominant tuning for

102 ted with PIVC, and receives projections from MSTd.

103 Furthermore, MST-312 treatment inhibited virus replication, as measur

104 We devised a Global MST Enrichment (GME) kit to enrich and nextgen sequence

105 genetically with another D. discoideum Hippo/MST homolog, KrsA, but the two genes are not functionall

106 These studies show that Hippo/MST proteins, like the tumor suppressor PTEN and oncogen

107 However, MST revealed correlations between FIB and gull source tr

108 expressed, purified, and crystallized human MST in the presence of the substrate 3-mercaptopyruvate

109 In human MST and putative VIP, multivoxel pattern analysis permit

110 l)]tris(2,4,6-trimethylbenzenesulfonam ido, [MST](3-).

111 to prepare the Co(II)/Ca(II) complex [Co(II)MST(mu-OH(2))Ca(II) subset15-crown-5(OH(2))](+) ([Co(II)

112 I)MST](-) to form the five-coordinate [Co(II)MST(OH(2))](-) complex that was used to prepare the Co(I

113 [Co(II)MST(OH(2))](-) was oxidized to form [Co(III)MST(OH(2))]

114 Water binds to [Co(II)MST](-) to form the five-coordinate [Co(II)MST(OH(2))](-

115 lso synthesized from the oxidation of [Co(II)MST](-) with iodosylbenzene (PhIO) in the presence of Ca

116 H(2))] that was further converted to [Co(III)MST(mu-OH)Ca(II) subset15-crown-5](+) ([Co(III)(mu-OH)Ca

117 )MST(OH(2))](-) was oxidized to form [Co(III)MST(OH(2))] that was further converted to [Co(III)MST(mu

118 In MST analysis, children with ASD showed a significant low

119 gions; 25%-30% of cells in MT and 40%-60% in MST are pattern direction selective.

120 examined in relation to overnight changes in MST performance.

121 gional applicability of enterococci hosts in MST application and highlights the significance of multi

122 ST was more variable in ECT than in MST.

123 long complex trajectories, and that cells in MSTd are specifically tuned to extract complex trajector

124 um of observed cells (radial to circular) in MSTd can simultaneously code curvature and heading acros

125 n dominance in PIVC to velocity dominance in MSTd.

126 ses overall, but was substantially larger in MSTd than PIVC or VIP.

127 MSTd based on the hypothesis that neurons in MSTd efficiently encode the continuum of large-field ret

128 fact that vestibular heading preferences in MSTd are more weakly clustered than visual preferences a

129 f peak directional tuning, with responses in MSTd typically being delayed by 100-150 ms relative to r

130 representation of visual heading signals in MSTd, but contrasts sharply with the body-centered repre

131 head position gain fields were strongest in MSTd and weakest in PIVC.

132 c flow selectivity in VIP was weaker than in MSTd but stronger than in VPS.

133 nses in VIP was significantly faster than in MSTd, whereas timing of optic flow responses did not dif

134 bular responses were stronger in VPS than in MSTd.

135 w responses in VPS were weaker than those in MSTd, whereas vestibular responses were stronger in VPS

136 However, tuning in MSTd neurons primarily reflects sensory inputs, whereas

137 resentation, unlike visual heading tuning in MSTd, which is approximately eye centered.

138 in VPS, intermediate in VIP, and weakest in MSTd.

139 ta demonstrate that the telomerase inhibitor MST-312 suppressed HSV replication at multiple steps of

140 ter large bilateral muscimol injections into MSTd.

141 s of STN (7 or 2 mg/kg) with CsA (20 mg/kg), MST was more than 100 (n=3) and 22 days (n=2), respectiv

142 of the upstream mammalian STE20-like kinase (MST) proteins.

143 Among our six implementations, KScons MST-MP (which uses the multiple structure alignment prio

144 Over the CASP10 and CASP11 sets, KScons MST-MP performs better than the leading methods using on

145 is of recall and precision finds that KScons MST-MP improves accuracy not only by improving identific

146 e often contradictory findings about macaque MSTd, and offers a biologically plausible account of a w

147 we describe a computational model of macaque MSTd based on the hypothesis that neurons in MSTd effici

148 The mammalian MST kinase family, which is related to the Hippo kinase

149 We show that many MSTd neurons exhibit the diagnostic form of cross-modal

150 The model (1) relies on two mechanisms (MST-MT feedback and disinhibition of opponent motion sig

151 ated rejection in primed, uninoculated mice (MST=12 days).

152 known repeat regions called microsatellites (MST).

153 includes recurrent interactions among model MSTd neurons.

154 At the population level, model MSTd accurately predicts eye velocity and heading using

155 nd IPd), superior temporal sulcus (areas MT, MST, FST, V4t, and IPa), inferotemporal region (areas TE

156 MT/MST responded to sound in congenitally blind adults, but

157 th neuronal recordings from macaque areas MT/MST.

158 d reduced functional connectivity between MT/MST and other visual regions.

159 /MST development, we used fMRI to compare MT/MST function in congenitally blind, late-blind, and sigh

160 The middle temporal complex (MT/MST) is a brain region specialized for the perception of

161 To test for a sensitive period in MT/MST development, we used fMRI to compare MT/MST function

162 itive period for visual specialization in MT/MST.

163 so suggests that the auditory response of MT/MST is selective for motion.

164 ack projections from prefrontal cortex to MT/MST.

165 e MSTs for a data set and find that multiple MSTs exist for each case in our survey.

166 A subpopulation of multisensory MSTd cells with congruent visual and vestibular heading

167 Moreover, the presence of 20 muM to 100 muM MST-312 during infection led to a 2.5- to 5.5-log10 decr

168 double the rates of veterans with a negative MST screen (0.7%, 1.8%, and 4.3%, respectively).

169 detects in evaluating the performance of new MST host strains.

170 0 days; P = 0.03), and from BALB/c into NOD (MST: 12.0 vs. 5.5 days; P = 0.003).

171 .0 days; P = 0.004), from NOD.SCID into NOD (MST: 23.5 vs. 14.0 days; P = 0.03), and from BALB/c into

172 A novel MST method for superfast examination of enzyme kinetics

173 ed before initiation and after completion of MST using the Scale for Suicide Ideation (SSI).

174 After completion of MST, patients had a mean SSI score of 4.2 (6.3) (pre-pos

175 The contribution of MST versus the other two H2S generators, cystathionine b

176 6), but more expensive including the cost of MST, although not significantly so ( pound5,687 versus p

177 n of suicidal ideation following a course of MST.

178 cs are not used to assess the credibility of MST estimations.

179 A cost-offset evaluation of MST based on data from a randomised controlled trial con

180 essed within 1 week before the initiation of MST treatment using the TMS-EEG measures of cortical inh

181 ling approach improves the interpretation of MST data, especially when fecal pollution from the same

182 ed to evaluate and verify the performance of MST assays and, therefore, to identify important sources

183 Sensitivity (percentage true positives) of MST results in sewage and animal waste samples (21-33%)

184 he KOS1.1 strain of HSV-1 in the presence of MST-312.

185 nt in the RASSF pathway is the regulation of MST kinases, which are main effectors of RASSF-induced a

186 used it to probe the complex selectivity of MST neurons.

187 The crystal structure of MST reveals a mixture of the product complex containing

188 In support of MST, after fire, forest structure appears to approximate

189 were part of an open-label clinical trial of MST treatment.

190 se properties might simply be a byproduct of MSTd neurons performing dimensionality reduction on thei

191 selectivity, might simply be a byproduct of MSTd neurons performing dimensionality reduction on thei

192 del challenges the view that the function of MSTd is heading estimation, based on our analysis we cla

193 However, the majority of MSTd neurons respond optimally to spiral patterns, rathe

194 te neurophysiological response properties of MSTd cells, such as 3D translation and rotation selectiv

195 he often nonintuitive response properties of MSTd neurons; (2) suggest that response properties, such

196 By measuring responses of MSTd neurons in two male rhesus monkeys and by applying

197 disparity selectivity and heading tuning of MSTd and VIP cells using random-dot stimuli.

198 ifficult to evaluate because many studies on MST have been conducted at high pH and have used varied

199 lses delivered through the ECT electrodes or MST coil.

200 s identification of the most credible MST or MSTs by using a bootstrapping metric.

201 Overall, MST data enabled management action despite an inability

202 ctivation techniques to artificially perturb MSTd activity while monitoring behavioral performance.

203 Each unit increase in preoperative MST score predicted longer LOSs of 2.5 d (95% CI: 1.5, 3

204 suppressor binds and activates proapoptotic MST kinases.

205 ver, STN 20 mg/kg and CsA 20 mg/kg prolonged MST to more than 100 days (n=5).

206 ged in mice treated with the early protocol (MST = 48 days), but most were rejected by d100.

207 Here, we survey published MSTs previously used to infer microbial population struc

208 ed assays appear to be suitable quantitative MST tools beyond the regional level while the targeted h

209 n factor to compensate the partially relaxed MST experiments, thus allowing measurement of enzyme kin

210 top-down spatial location signals, reshaping MSTd's response properties through task-dependent intera

211 i) presenting a single, arbitrarily selected MST illustrates only one of potentially many equally opt

212 One-third of disparity-selective MSTd cells reversed their depth preference for opposite

213 ing IgG1 antibody was significantly shorter (MST=14 days), whereas the survival using depleting IgG2a

214 Mercaptopyruvate sulfurtransferase (MST) is a source of endogenous H2S, a gaseous signaling

215 We aimed to develop a novel superfast MST method that can accurately quantify ATP production r

216 d on the finger-tapping motor sequence task (MST) at bedtime and tested the following morning.

217 Neurons in the medial superior temporal (MST) area of the primate visual cortex respond selective

218 (MT) area and the medial superior temporal (MST) area: two neighboring extrastriate cortical areas o

219 ed from the dorsal medial superior temporal (MSTd) and ventral intraparietal (VIP) areas of monkeys d

220 rons in the dorsal medial superior temporal (MSTd) and ventral intraparietal (VIP) areas of the macaq

221 rved in the dorsal medial superior temporal (MSTd) and ventral intraparietal areas.

222 l subregion of the medial superior temporal (MSTd) area of the macaque respond to large, complex patt

223 that a variety of medial superior temporal (MSTd) neural response properties could be derived from M

224 ed secondary K skin grafts in the long term (MST>100 days) compared to accelerated rejection in prime

225 ed higher speeds and nearer disparities than MSTd cells.

226 simulated and for gene expression data that MST-based tests discriminate well against shift and scal

227 Together, these findings demonstrate that MST-312 interferes with the HSV life cycle.

228 In our simulation study, we demonstrate that MST-based tests have power that is for many settings com

229 Additionally, we determined that MST-312 has the largest impact on viral events that take

230 orted in this study support the finding that MST+YOT has scope for cost-savings when compared to YOT

231 Recent research suggests that MST may be a determinant in several factors associated w

232 We conclude that MSTd responses are not rigidly linked to specific stimul

233 However, ample evidence suggests that MSTd neurons exhibit a continuum of visual response sele

234 The MST enzymes (menaquinone, siderophore, and tryptophan bi

235 The MST treatments were administered under general anesthesi

236 The MST+YOT group were significantly cheaper in terms of YOT

237 assessed whether low protein intakes and the MST score were predictive of LOS.Total protein intakes w

238 merase and lyase activities performed by the MST enzymes are functionally conserved.

239 ident in both groups, but were higher in the MST+YOT group.

240 chemical data proved the plausibility of the MST findings.

241 horylation, promoting an active state of the MST kinases and favoring induction of apoptosis.

242 ese results underscore the importance of the MST screen as a clinically important marker of reintegra

243 failed to show overnight improvement on the MST and differed significantly from control participants

244 predicted less overnight improvement on the MST.

245 At 18-month follow-up, the MST+YOT group cost less in terms of criminal activity (

246 rmed intramolecular hydrogen bonds with the [MST](3-) ligand.

247 Metabolic scaling theory (MST) posits that the scaling exponents among plant heigh

248 potheses regarding metabolic scaling theory (MST), C recovery and biodiversity.

249 nt scaling models (Metabolic Scaling Theory (MST), Geometric Similarity, and Stress Similarity) in sa

250 Magnetic seizure therapy (MST) induces a weaker and more focal electric field than

251 Magnetic seizure therapy (MST) is a novel therapeutic option for treatment-resista

252 frontomedial) and magnetic seizure therapy (MST) with cap coil on vertex.

253 seizures, as with magnetic seizure therapy (MST), or modifications to ECT.

254 demonstrate that microscale thermophoresis (MST) is a valuable method for screening for ligands and

255 oring (QCM-D) and microscale thermophoresis (MST) we have been able to determine DHFR-TS binding kine

256 resonance (SPR), microscale thermophoresis (MST), and theoretical models for determining the thermod

257 proximately 11:30 PM Mountain Standard Time (MST) on Friday, February 14, 2014.

258 grafts with increased median survival time (MST) more than 169 days compared to uninoculated (MST=18

259 nanogels increased the median survival time (MST) of lupus-prone NZB/W F1 mice by 3 months with proph

260 mg/kg twice daily, the median survival time (MST) was 27 days (n=4).

261 cceptance: the BMT/renal mean survival time (MST, 76 days) was not significantly different than the r

262 rom BALB/c into C57BL/6 (mean survival time [MST]: 16.5 vs. 12.0 days; P = 0.004), from NOD.SCID into

263 d with untreated mice (median survival time [MST]=10 days).

264 aged 11-17 years, were randomly allocated to MST+YOT (n = 56) or YOT alone (n = 52).

265 We instead propose a systematic approach to MST estimation that bases analyses on the optimal comput

266 vertheless, there are significant caveats to MST algorithms that have been largely ignored in molecul

267 By comparison to MSTd, VIP contains fewer disparity-selective neurons (41

268 inated by vestibular signals, in contrast to MSTd, where optic flow tuning typically dominates.

269 erms of vestibular processing, but distal to MSTd in terms of optic flow processing.

270 findings suggest that VIP may be proximal to MSTd in terms of vestibular processing but hierarchicall

271 ese findings suggest that VPS is proximal to MSTd in terms of vestibular processing, but distal to MS

272 lar processing but hierarchically similar to MSTd in terms of optic flow processing.

273 increased substantially from PIVC to VIP to MSTd.

274 ed preoperative Malnutrition Screening Tool (MST) score, 3-d food records, postoperative nausea, LOS,

275 The microbial source tracking (MST) approach presented here provides a framework for fu

276 tigation included microbial source tracking (MST) for human, gull, and canine fecal sources, monitori

277 assays for microbial fecal source tracking (MST) have been developed and evaluated in recent years.

278 oped and used for microbial source tracking (MST) in environmental waters.

279 teria, protozoa), microbial source tracking (MST) markers, and antibiotic resistance genes was tested

280 entation of microbial fecal source tracking (MST) methods in drinking water management is limited by

281 FIB) and emerging microbial source tracking (MST) methods may indicate the presence and even the like

282 s are employed in microbial source tracking (MST) studies globally, however little is known regarding

283 ation provided by microbial source tracking (MST) to map hot spots (i.e., likely sources) of fecal co

284 d sewage-specific microbial source tracking (MST) tools using enterococci bacteriophages and evaluate

285 Quantitative Microbial Source Tracking (MST) was employed from 2012 to 2015 to inventory sources

286 Current microbial source-tracking (MST) methods, employed to determine sources of fecal con

287 ivision, termed mitotic somal translocation (MST).

288 Military sexual trauma (MST) is associated with adverse physical and mental heal

289 uses a cluster-based minimum spanning tree (MST) approach to order cells.

290 Type I error rates of minimum-spanning tree (MST)-based non-parametric multivariate tests with severa

291 ary graph, as well as minimum spanning tree (MST).

292 Minimum spanning trees (MSTs) are frequently used in molecular epidemiology rese

293 cation by the micellar selectivity triangle (MST).

294 ping (MLST) and multispacer sequence typing (MST).

295 more than 169 days compared to uninoculated (MST=18.5 days) and rAAV-K-treated controls (MST=19 days)

296 W F1 mice by 3 months with prophylactic use (MST was 50 weeks versus 38 weeks without treatment), and

297 aches to studying population structure using MSTs are inadequate.

298 model, islet survival was prolonged as well (MST: muMT = 32.5 vs. WT = 14 days; P = 0.002).

299 ons where observations are inconsistent with MST we find that departure from theory corresponds with

300 require a direct interaction of RASSF1A with MST kinases or the activation of the hippo pathway.