ライフサイエンスコーパス: MT

1 (MT) CH4 or 2.72 Gigatonnes (Gt) CO2 -eq (1 MT = 10(12) g, 1 Gt = 10(15) g) from ruminant livestock,

2 rotein isoforms with three (3R) or four (4R) MT binding repeats.

3 lserotonin (NAS), and 5-methoxytryptamine (5-MT).

4 ide synthetases have the same C1-A1-T1-C2-A2-MT-T2a-T2b-C3 domain organization.

5 tip, resulting in the formation of aberrant MT loops.

6 Those randomised to additional MT underwent thrombectomy using any Conformite Europeene

7 nificance of MT, we exogenously administered MT-I after cerebral I/RI and found that it produced neur

8 etriever or MT with a stent retriever alone (MT group).

9 Rab11A RE transport primarily along MT; therefore, investigation of the role of MT in vRNA a

10 IPs) that respond to signaling cues to alter MT behavior.

11 (designated AUG) including AUG8, which is an MT-associated protein (MAP).

12 coding gene evolution-D6Ertd527e-in which an MT LTR provided a promoter and the 5' exon with a functi

13 chanism by which WHAMM coordinates actin and MT networks, the two major cytoskeletal systems involved

14 ly enhancing the effects of KT diffusion and MT pivoting.

15 WQ-IDL and MT-WQ-IDL were also more effective than WQ in blocking H

16 r MT-WQ, the conjugated peptides, WQ-IDL and MT-WQ-IDL, showed much more potent activities than WQ an

17 the analysis, 160 (55.0%) underwent IVT and MT (mean [SD] age, 67 [13] years; 97 female [60.6%]), an

18 lasminogen activator followed by MT (IVT and MT group) with the use of a stent retriever or MT with a

19 more often in patients who received IVT and MT vs MT alone (27% vs 14%, P = .006).

20 was normal as assayed by in vitro kinase and MT phosphopeptide mapping.

21 l relationship between tubulin structure and MT stability.

22 vidence that the relationship between V1 and MT activity is nonlinear and is well described by divisi

23 es the weights of connections between V1 and MT than by a mechanism that modulates responses in eithe

24 not evoke spiking responses in areas V4 and MT during memory, the gain of visual responses in these

25 tein interaction between viral particles and MTs.

26 ) coordination to amyloidogenic proteins and MTs, and their redox properties in generation and/or sil

27 erage, higher velocities between antialigned MTs than tetrameric motors.

28 The gene coding for middle T antigen (MT) is the murine polyomavirus oncogene most responsible

29 Middle T antigen (MT), the principal oncoprotein of murine polyomavirus, t

30 serve neural information processing in area MT and other cortical areas.SIGNIFICANCE STATEMENT Propa

31 pression, whereas unisensory neurons in area MT do not.

32 tory influences in the middle temporal area (MT) of the macaque visual cortex, using electrophysiolog

33 M's MT-binding motif (MBM) assembling around MTs using cryo-electron microscopy and verified it with

34 She1 regulates dynein activity along astral MTs and directs spindle movements toward the bud cell.

35 between the MTs, the cytoplasm-filled astral MTs behave like a porous medium, with its permeability d

36 In addition to localizing to astral MTs, She1 also targets to the spindle, but its role on t

37 rs and move unidirectionally on the attached MT.

38 Because MT localization is a hallmark of most IQD family members

39 the transport of individual MTs, or because MTs translocate forward in bulk is unclear.

40 guided by fractional flow reserve with best MT in patients with stable coronary artery disease to as

41 a pronounced cationic dynamics in PPy-bonded MT piezosensors despite of the undoped-PPy preference fo

42 we investigate the role of TPX2 in branching MT nucleation.

43 perty necessary for TPX2 to induce branching MT nucleation is contained within newly identified gamma

44 may activate gamma-TuRC to promote branching MT nucleation.

45 TPX2 to gamma-TuRC intact, whereas branching MT nucleation is abolished, suggesting that TPX2 may act

46 h human tau expression restored MT bundling, MT penetration into the growth cone periphery and close

47 ctivator would be delayed by 12 minutes, but MT would be performed 91 minutes sooner if patients were

48 ith tissue plasminogen activator followed by MT (IVT and MT group) with the use of a stent retriever

49 the crystal structure of the 6-HB formed by MT-WQ-IDL and N46 and found that, besides the N-terminal

50 organization of the MT array is regulated by MT-associated proteins (MAPs), which include a subset of

51 IQD proteins in Arabidopsis altered cellular MT orientation, cell shape, and organ morphology.

52 ion into the growth cone periphery and close MT apposition to actin filaments in filopodia.

53 lexibly to serious challenges of compromised MT-dependent MT nucleation to complete mitosis and cytok

54 ce elastic light scattering (RELS) confirmed MT swelling/shrinking, ion dynamics, and osmotic water t

55 Consistently, MT and spindle length regulators were identified in EML1

56 and establish a role for APC in coordinating MTs and actin at FAs to direct cell migration.

57 essential role in microtubule (MT)-dependent MT nucleation by recruiting the gamma-tubulin complex to

58 rious challenges of compromised MT-dependent MT nucleation to complete mitosis and cytokinesis.

59 In particular, KT-derived MTs play important roles both by making a significant co

60 ecifically from KTs, we show that KT-derived MTs shorten the half-life of noncaptured KTs from 48-49

61 Wnt5a gradients, likely due to disorganized MTs that failed to extend into the peripheral domain and

62 RNA colocalization is dependent upon dynamic MT filaments.

63 odimers, and co-assemble into the endogenous MT lattice.

64 , prospective clinical trials that evaluated MT for AIS (Solitaire With the Intention for Thrombectom

65 n disease-mimicking dhc-1 alleles, excessive MT growth and collapse occur at the dendrite tip, result

66 e is critical for MT binding and facilitates MT nucleation.

67 Our results identify that MCAK promotes fast MT growth speeds in ECs cultured on compliant 2D ECMs bu

68 ary clinical outcomes significantly favoured MT (absolute difference in mRS 0-2 of 22% and adjusted O

69 l that this interaction mode is critical for MT binding and facilitates MT nucleation.

70 ly to EB1 and that Tau competes with EB1 for MT binding.

71 However, a function for MT nucleation from the NE in nuclear positioning has not

72 While interactions with and functions for MT motor proteins are well characterized and extensively

73 other centrosomal proteins, is required for MT nucleation from the NE.

74 ng from non-cell-autonomous requirements for MTs in regulating proliferation, differentiation, and ti

75 ion are two examples of insights coming from MT.

76 channels in CA3 and Zn(2+) mobilization from MT-III predominating in CA1.

77 in which tau acetylation disengages tau from MTs and also promotes tau aggregation.

78 ubule (MT) nucleation at the Golgi generates MT network asymmetry in motile vertebrate cells.

79 the MT cytoskeleton and identify loss of Glu-MTs and RNA mislocalization as common outcomes of ALS pa

80 nchymal stem cells (MSCs) derived from human MT in the pathogenesis of bone outgrowth.

81 of TBA-7 led to the formation of hyperstable MTs and the generation of ectopic neurites; the lack of

82 tween sensorineural disease and anomalies in MT behavior and describe a syndromic LCA unrelated to ci

83 the MAP65-3 gene lead to serious defects in MT organization in the phragmoplast and cause failures i

84 mma1 (PLCgamma1) have all been implicated in MT transformation.

85 T patterns, which point to a role of IQDs in MT organization and dynamics.

86 n their cytotoxic concentrations observed in MT-2 cells.

87 g may contribute partly to bone outgrowth in MT, as mediated by enhanced MSC-driven osteogenic differ

88 rostimulation in V1 paired with recording in MT to provide causal evidence that the relationship betw

89 rowing ends, which has a fundamental role in MT polymerisation.

90 r data confirm the predictions of the SSN in MT, suggesting that the SSN computations might be a gene

91 ion dynamics, and osmotic water transfer in MTs, as well as the effects of exposure to a drug valino

92 which map to the exterior surface, increase MT stability, and cause ectopic neurite growth.

93 howed that netrin-1 differentially increased MT dynamics in the GC with more MT growth in the distal

94 tip of the axon, the transport of individual MTs, or because MTs translocate forward in bulk is uncle

95 ies, Dia1 and Dia2 facilitated HIV-1-induced MT stabilization and the intracellular motility of virus

96 Mechanistically, cold-induced MT depolymerization experiments demonstrated a hyper-sta

97 A and vRNA segments in the absence of intact MT filaments, we analyzed the three-dimensional spatial

98 rsuit is consistent with a short integration MT subpopulation.

99 stabilization of both mitotic and interphase MTs.

100 In cells, She1 stabilizes interpolar MTs, preventing spindle deformations during movement, an

101 Several domains of TPX2 contribute to its MT-binding and bundling activities.

102 lin through a small peptide motif within its MT-binding domain.

103 /Cdk1 activity and that MYPT1 destabilizes k-MT attachments by negatively regulating Plk1 at kinetoch

104 ise regulation of kinetochore microtubule (k-MT) attachment stability.

105 atous polyposis coli (APC), which is a known MT-associated protein, directly nucleates actin assembly

106 by inhibiting the correction of erroneous KT-MT interactions.

107 bers, we quantitatively analyzed GFP-labeled MT arrays in Nicotiana benthamiana cells transiently exp

108 to investigate the effects of cross-linking MT plus ends and F-actin in Drosophila melanogaster S2 c

109 She1 binds and cross-links MTs via a C-terminal MT-binding site.

110 es of short MTs and the immobility of longer MTs.

111 f short MTs and increased mobility of longer MTs.

112 gated ion channel: normal mechanotransducer (MT) channels at the tips of the stereocilia, activated b

113 ning through recruitment of Akap450-mediated MT nucleation activity to the NE.

114 y at residues K280/K281 impairs tau-mediated MT stabilization, and enhances the formation of fibrilla

115 he role of membrane-type metalloproteinases (MT-MMPs) in excitatory synaptogenesis.

116 the transcriptome, we found metallothionein (MT, particularly MT-I) transcripts were dramatically up-

117 The methyltransferase (MT) domain of Tv6-931 can perform two consecutive alpha-

118 Eml1, a microtubule (MT)-associated protein of the EMAP family, is impaired i

119 reorganization of the actin and microtubule (MT) cytoskeletons.

120 cts on actin microfilaments and microtubule (MT) organization across the cell cytosol.

121 ontrolling actin nucleation and microtubule (MT) stabilization to facilitate processes such as cell p

122 protein-protein interactions at microtubule (MT) growing ends, which has a fundamental role in MT pol

123 ganizing centers (MTOCs) direct microtubule (MT) organization to exert diverse cell-type-specific fun

124 polarity sorting" mechanism for microtubule (MT) organization in developing axons.

125 plex plays an essential role in microtubule (MT)-dependent MT nucleation by recruiting the gamma-tubu

126 stead on its ability to inhibit microtubule (MT) dynamics.

127 Noncentrosomal microtubule (MT) nucleation at the Golgi generates MT network asymmet

128 a critical regulator of nuclear microtubule (MT) dynamics in the budding yeast Saccharomyces cerevisi

129 Modulation of microtubule (MT) dynamics is a key event of cytoskeleton remodeling i

130 A number of microtubule (MT)-stabilizing agents (MSAs) have demonstrated or predi

131 alpha2 knockdown also perturbed microtubule (MT) organization by considerable down-regulation of MT p

132 tight coordination between the microtubule (MT) and actin cytoskeletons, but the mechanisms underlyi

133 that it rotates relative to the microtubule (MT) while walking.

134 Microtubules (MTs) are key cellular effectors of neuronal displacement

135 Microtubules (MTs) form a rapidly adaptable network of filaments that

136 rt (IFT), ferrying cargo along microtubules (MTs) toward the tips of cilia.

137 and its two associated astral microtubules (MTs).

138 Ciliary microtubules (MTs) are extensively decorated with post-translational m

139 he mitotic spindle consists of microtubules (MTs), which are nucleated by the gamma-tubulin ring comp

140 nse, confined mixture of rigid microtubules (MTs) and active springs that have arms that cross-link n

141 uronal protein that stabilizes microtubules (MTs), but the mechanism of this activity remains poorly

142 py confirmed that MHV-A59 used microtubules (MTs) as a conduit to reach the cell surface and restrict

143 These may influence interphase and mitotic MT mechanisms and indeed, centrosome and primary cilia w

144 In the "heterogeneous Golgi" model, MT nucleation is dramatically up-regulated at discrete a

145 d we show that smooth eye movements modulate MT responses in a systematic, temporally precise, and di

146 ly increased MT dynamics in the GC with more MT growth in the distal than the proximal region of the

147 s that have arms that cross-link neighboring MT pairs and move unidirectionally on the attached MT.

148 dentify functional significance for neuronal MT stability and suggest a mechanism for cellular dysfun

149 Neuronal MTs are highly static, yet the mechanisms and functional

150 -tubulin complex to MT walls to generate new MTs [1].

151 birth, appearing 2 days earlier than normal MT channels, and being down-regulated with the emergence

152 of Piezo2-null mice, even though the normal MT current persists.

153 lopment, but it does not underlie the normal MT current.

154 fficient to recruit gamma-TuRCs and nucleate MTs.

155 DP tubulin has little impact on the observed MT stabilization.

156 ion analyses of the simultaneous activity of MT and LIP during individual decisions.

157 s cytoskeletal stability and the activity of MT-associated proteins such as kinesins.

158 erminal MT hook tail, the IDL tail anchor of MT-WQ-IDL also binds with the shallow hydrophobic pocket

159 However, using knock-out animals (of MT-III and vesicular Zn(2+) transporter, ZnT3) and chann

160 We suggest that cell-specific control of MT glutamylation may be a conserved mechanism to special

161 This indicates that disruption of MT dynamics interferes with neurite outgrowth, not by di

162 Some theories on the etiology of MT have been postulated, such as genetic factors, mastic

163 ion in vivo and highlights the importance of MT flexibility in N-C coupling and neuronal-branching re

164 ation in cytoplasmic foci was independent of MT.

165 otoxicity and demonstrate that inhibition of MT dynamics and accumulation of PTMs are driving factors

166 This reveals a new mode of MT regulation in response to changing gaseous biofilm mi

167 developed dimer-scale computational model of MT dynamics.

168 nality mechanosensing-mediated regulation of MT growth dynamics through a myosin-II-dependent signali

169 gement uncouples MCAK-mediated regulation of MT growth persistence from myosin-II-mediated regulation

170 anization by considerable down-regulation of MT polymerization via changes in the spatiotemporal expr

171 In this study, we analyze responses of MT neurons as a function of both retinal velocity and di

172 his study is the first to assess the role of MT in influenza virus replication in human bronchial air

173 ation was performed to determine the role of MT in the assembly of multiple vRNA segments.

174 We explored the role of MT in vRNA assembly and replication by using multiple IA

175 MT; therefore, investigation of the role of MT in vRNA assembly is warranted.

176 Our results describing the role of MT in vRNA transport and assembly expand upon previous s

177 e systems, we provide evidence for a role of MT nucleation from the NE on nuclear spreading in myotub

178 Finally, to confirm the significance of MT, we exogenously administered MT-I after cerebral I/RI

179 rowth, not by disrupting the net assembly of MTs at the growth cone, but rather because it alters the

180 Specifically, detyrosination of MTs facilitates an interaction with intermediate filamen

181 vide a working model of direct modulation of MTs by guidance cues in growth cone navigation but also

182 ity decreasing with increasing the number of MTs.

183 models, including the pushing or pulling of MTs at the cortex and the pulling of MTs by cytoplasmica

184 ling of MTs at the cortex and the pulling of MTs by cytoplasmically bound force generators.

185 tron microscopy (cryo-EM) reconstructions of MTs stabilized by the taxane-site binders Taxol and zamp

186 that power the bulk forward translocation of MTs.

187 potential impact of these Tau activities on MT stabilization, we incorporated them into our previous

188 y-trial variability in LIP did not depend on MT activity.

189 ing activities have a much greater effect on MT stability than do longitudinal crosslinking activitie

190 s were genetically separable from effects on MT stabilization.

191 to examine the effects of MCAK expression on MT growth dynamics and EC branching morphology.

192 wed for many viruses, this review focuses on MT filaments themselves.

193 It was also concentrated on MTs in the spindle midzone and the phragmoplast.

194 Altering the dynamics of actin or MT polymerization, for example, is a common strategy emp

195 group) with the use of a stent retriever or MT with a stent retriever alone (MT group).

196 -Leu) to the C terminus of CHR peptide WQ or MT-WQ, the conjugated peptides, WQ-IDL and MT-WQ-IDL, sh

197 we identified more than 800 LTRs from ORR1, MT, MT2, and MLT families, which resemble mobile gene-re

198 ored dynein pool interacts with plus-end-out MTs to stabilize MTs and allow efficient retrograde tran

199 , we found metallothionein (MT, particularly MT-I) transcripts were dramatically up-regulated.

200 As brain-penetrant MT-stabilizing agents have proven effective against tau-

201 d with acentrosomal spindle and phragmoplast MT arrays in patterns indistinguishable from those of th

202 formation of elongated bipolar phragmoplast MT arrays in the mutant.

203 increased straightness of newly polymerized MTs, and structural modeling data suggest a conformation

204 uncovered that MTs nucleate from preexisting MTs within the mitotic spindle, which requires the prote

205 ts Stu2 to budding yeast KTs, which promotes MT generation there.

206 calization and thereby contributes to proper MT cytoskeletal organization in interphase and mitosis.

207 LIP responses recapitulated MT early weighting and contained a choice-dependent buil

208 that in patients with acute stroke receiving MT, success should be redefined as achieving a mTICI 3 s

209 interdimer interfaces, significantly reduce MT stability, and cause severe neurite growth defects; a

210 f core pericentriolar proteins that regulate MT assembly at centrosomes.

211 As pathogenic cargos, viruses require MTs to transport to and from their intracellular sites o

212 periments with human tau expression restored MT bundling, MT penetration into the growth cone periphe

213 uit to reach the cell surface and restricted MT-mediated Cx43 delivery to the cell membrane.

214 ells recapitulates all aspects of reversible MT depolymerization and transient formation of +TIPs bar

215 ucted a high-resolution structure of WHAMM's MT-binding motif (MBM) assembling around MTs using cryo-

216 r will produce disordered transport of short MTs and increased mobility of longer MTs.

217 explanation for the frequent pauses of short MTs and the immobility of longer MTs.

218 We further show MT depolymerization within biofilms is regulated by the

219 Most hospitals do not have on-site MT facilities, and most patients need to be transferred

220 tured on compliant 2D ECMs but promotes slow MT growth speeds in ECs cultured on compliant 3D ECMs, a

221 f the two MTs, produce large polarity-sorted MT clusters, whereas tetrameric motors, with motile arms

222 ng GFP-IQD fusions and observed IQD-specific MT patterns, which point to a role of IQDs in MT organiz

223 AM with polymerized TUBB3, a neuron-specific MT subunit in the brain, is required for netrin-1-mediat

224 The core SPOP(MT);MYC(High) transcriptomic response, defined by the ov

225 We propose SPOP(MT)-induced stabilization of c-MYC protein as a novel me

226 nse, defined by the overlap between the SPOP(MT) and c-MYC transcriptomic programmes, was also associ

227 transcription factor and that without SrbA, MTs are maintained as biofilms form.

228 interacts with plus-end-out MTs to stabilize MTs and allow efficient retrograde transport.

229 e molecular mechanism of how TPX2 stimulates MT assembly remains unknown because structural informati

230 he stepping mechanisms of other well-studied MT motors, because it is characterized by constant small

231 We developed a genetic toolkit to study MT dynamics and function in diverse cells.

232 This raises the possibility of targeting MT dynamics in the design of new therapeutic agents.

233 Numbers of missing teeth (MT) were also recorded.

234 from the motion-processing medial temporal (MT) area of anesthetized male marmosets.

235 on-making, responses in the middle temporal (MT) and lateral intraparietal (LIP) areas appear to map

236 and neural activity in the middle temporal (MT) area of the macaque monkey to study the neural mecha

237 1 binds and cross-links MTs via a C-terminal MT-binding site.

238 d N46 and found that, besides the N-terminal MT hook tail, the IDL tail anchor of MT-WQ-IDL also bind

239 Using TRE-EB1-GFP mice, we found that MT dynamics are strongly suppressed in differentiated ke

240 es represent a clear proof of principle that MT-Hec1-interacting compounds may represent novel powerf

241 We first show that MT dynamics are perturbed in mutant progenitor cells in

242 Recent studies also suggest that MT dynamics in the adult brain function in the essential

243 Recently, it was uncovered that MTs nucleate from preexisting MTs within the mitotic spi

244 The MT-associated protein She1 regulates dynein activity alo

245 g pattern observed as dynein moves along the MT.

246 kinesin-dependent mechanism controlling the MT cytoskeleton and identify loss of Glu-MTs and RNA mis

247 ihood that KIF3AB motors dissociate from the MT, resulting in transport by KIF17 motors alone, unencu

248 required to dislodge the motor head from the MT, to show that nearly three-quarters of the step occur

249 ng domain to MT plus ends and cross-link the MT and F-actin networks.

250 The dynamic behavior and organization of the MT array is regulated by MT-associated proteins (MAPs),

251 the spatial organization and dynamics of the MT array, mediated by virus- or host-induced changes to

252 ability to rearrange the architecture of the MT cytoskeleton.

253 nly to mass changes in the lower part of the MT film, penetrated by the acoustic wave, is able to det

254 o independently regulate the dynamics of the MT tip and the stability of the lattice.

255 ns by creating a coarse-grained model of the MT-kinesin complex, which reproduces the measured stall

256 een retrograde and anterograde forces on the MT, providing an explanation for the frequent pauses of

257 cally infected with HTLV-1, particularly the MT-2 cell line, which harbors truncated proviruses and e

258 s to the mitochondrial surface, recruits the MT nucleator gamma-tubulin ring complex (gamma-TuRC), an

259 n-seam) contacts by which it regularizes the MT lattice.

260 C1 proximal kinase Sch9/S6K1 to regulate the MT polymerase Stu2/XMAP215.

261 a conceptual model where Tau stabilizes the MT lattice by strengthening lateral interactions between

262 ure of a central region of TPX2 bound to the MT surface.

263 nd temporal cortical visual areas within the MT complex.

264 st, we show that, because of HIs between the MTs, the cytoplasm-filled astral MTs behave like a porou

265 clitaxel or nocodazole due to changes in the MTs network.

266 Therefore, MT glutamylation, as part of the tubulin code, controls

267 These MT-interacting elements overlap with the binding site of

268 These MTs suppress Rho activation, nonmuscle myosin II bipolar

269 keletons, but the mechanisms underlying this MT-actin cross talk have remained poorly understood.

270 ith amplitude titrations of motor threshold (MT) and seizure threshold (ST) in four nonhuman primates

271 ular treatment with mechanical thrombectomy (MT) is beneficial for patients with acute stroke sufferi

272 s (IVT) followed by mechanical thrombectomy (MT) is recommended to treat acute ischemic stroke (AIS)

273 sion of EB1 (end-binding protein 1), a +TIP (MT plus-end tracking protein).

274 ediated by virus- or host-induced changes to MT regulatory proteins, not only play a central role in

275 n by recruiting the gamma-tubulin complex to MT walls to generate new MTs [1].

276 porally recruit an F-actin binding domain to MT plus ends and cross-link the MT and F-actin networks.

277 4 emissions in 2014 was 97.1 million tonnes (MT) CH4 or 2.72 Gigatonnes (Gt) CO2 -eq (1 MT = 10(12) g

278 CPs) that exhibit biased localization toward MT minus ends.

279 We show that SxIP-iLID can track MT plus ends and recruit tgRFP-SspB upon blue light acti

280 rs, with a motile arm on only one of the two MTs, produce large polarity-sorted MT clusters, whereas

281 are routinely expanded in mesenchymal-type (MT) conditions, we previously showed that they acquire b

282 ) is of added benefit in patients undergoing MT.

283 7 female [60.6%]), and 131 (45.0%) underwent MT alone (mean [SD] age, 69 [12] years; 71 [55.7%] femal

284 mitochondrial unfolded protein response (UPR(MT)).

285 resistance to chronic malfunction of the UPR(MT) Given the increasingly recognized role of mitochondr

286 of mitochondrial signaling in which the UPR(MT) pathway, under disease-associated, context-specific

287 d ATFS-1-associated dysregulation of the UPR(MT) synergistically potentiate dopaminergic neurotoxicit

288 variants have the capacity to induce the UPR(MT), but also that coexpression of alphaS and ATFS-1-ass

289 to show that the attention dependence of V1-MT correlations is better explained by a mechanism in wh

290 ng the V247fs mutation (V247fs-WT and V247fs-MT), and iPSC line in which the V247fs mutation was corr

291 by CRISPR/Cas9-based genome editing (V247fs-MT-correction).

292 her IFC or an active control region (area V5/MT).

293 often in patients who received IVT and MT vs MT alone (27% vs 14%, P = .006).

294 and is economically attractive compared with MT alone in patients with stable coronary artery disease

295 st-effectiveness ratio for PCI compared with MT was $17 300 per quality-adjusted life-year at 2 years

296 onto theoretically defined quantities, with MT representing instantaneous motion evidence and LIP re

297 ith anterior circulation stroke treated with MT and achieving a final mTICI score 2b or 3.

298 sis used data from 291 patients treated with MT included in 2 large, multicenter, prospective clinica

299 formation about the interaction of TPX2 with MTs is lacking.

300 Yeast MTs were not observed to undergo compaction at the inter