ライフサイエンスコーパス: MVR

1 MVR and receptor saturation both occur at some high p sy

2 MVR blade treatment across 170.0 +/- 14.1 degrees of TM

3 MVR consequently represents a widespread mechanism that

4 MVR data suggest that mouse minisatellites mutate mainly

5 MVR determines the temporal and spatial dispersion of tr

6 MVR may be an appropriate strategy for children <5 years

7 MVR or MV repair after previous CABG is associated with

8 MVR permits small presynaptic voltage changes to elicit

9 MVR typing could, therefore, improve the ascertainment o

10 MVR typing of rare-length alleles indicates that they ar

11 MVR typing of the common alleles a1, a2, a3, and a4 show

12 MVR via conventional sternotomy has been an established

13 MVR was initially identified at specialized synapses but

14 MVR was performed 176 times on 139 patients.

15 MVR, however, is preferred for select patients.

16 MVR-calibrated measurements of allele length yield rare

17 n additional reoperation: 4 received CABG, 2 MVR, and 2 MV repair.

18 There were 33 AVR (5.4%) and 38 MVR (7.9%) hospital deaths.

19 alve replacement) (35, 0.9%), AVR (231, 6%), MVR (41, 1.06%), CABG + others (95, 2.46%), and others (

20 re were 46 patients identified (37 MVP and 9 MVR).

21 y in 370 patients undergoing VR (249 AVR, 93 MVR, 28 DVR).

22 19 patients with an EF < or = 30% received a MVR using an undersized nonflexible complete ring.

23 l valve deterioration of bioprosthesis after MVR is higher than after AVR; after AVR, homografts and

24 th chronic MR before and 10 to 14 days after MVR.

25 The decline in EF after MVR for chronic MR is traditionally thought to be a cons

26 r AVR, and postoperative renal failure after MVR.

27 Significant limitation of function after MVR is uncommon.

28 Early mortality after MVR can be predicted on the basis of diagnosis and the s

29 survival was 95 +/- 1%; when mortality after MVR is included, 7-year survival was 83 +/- 6%.

30 thesis (66% vs. 79%, p = 0.02) but not after MVR.

31 after repair was better than survival after MVR for both PL-MVP (at 15 years, 41+/-5% versus 31+/-6%

32 All MVR and control patients underwent ablation under therap

33 P = .022) and MVR/SVP (66.2 +/- 12.4%, P = .017) groups than the MVR/N

34 was lower in the repair (1.8%, P = .046) and MVR/SVP (1.5%.

35 ion was BMVP in 64 patients, SMVP in 33, and MVR in 11.

36 Mortality after AVR and MVR is high at 10 to 15 years because of the associated

37 greater with bioprosthesis, both for AVR and MVR, and occurred at a much higher rate in those aged <6

38 pect to age (P = .002) and in the repair and MVR/SVP groups with respect to NYHA functional class and

39 odds ratio, 0.27, P < .05) and of repair and MVR/SVP on overall mortality (hazard ratios, 0.43, P < .

40 after either the sham procedure or anterior MVR; however, after posterior chordal-sparing MVR, theta

41 As MVR increases the likelihood of postsynaptic receptor sa

42 Operative mortality rates for AVR, MVR, combined CABG/AVR and combined CABG/ MVR were 4.00%

43 a mechanism by which a combination of basal MVR and low receptor saturation allow the presynaptic ac

44 These data can assist in choosing between MVR and alternative palliative strategies.

45 ortic valve replacement) (228, 5.9%), CABG + MVR (mitral valve replacement) (35, 0.9%), AVR (231, 6%)

46 R, MVR, combined CABG/AVR and combined CABG/ MVR were 4.00%, 6.04%, 6.80% and 13.29%, respectively.

47 ad CABG/mitral repair versus 56 who had CABG/MVR with preservation of the subvalvular apparatus.

48 ter CABG with mitral valve replacement (CABG/MVR).

49 t no valve replacement (n = 6), conventional MVR with chordal excision (n = 7), or chordal-sparing MV

50 After conventional MVR, baseline theta max fell by 66% to 81% in the antero

51 ular-ventricular integrity with conventional MVR reduced regional LV systolic torsion in the anterior

52 within an active zone is coordinated during MVR.

53 arious methods of chorda preservation during MVR to assess their impact on left ventricular systolic

54 We examined MVR at a ribbon synapse in a retinal slice preparation u

55 patients having smaller prostheses at first MVR (18.7+/-0.8 mm versus 22.4+/-3.6 mm, P=0.017).

56 (age <2 years and prosthesis <20 mm at first MVR) had an OR=46.3 compared with low-risk patients (age

57 or=2 years and prosthesis >or=20 mm at first MVR) over similar follow-up intervals.

58 sthesis survival was predicted only by first MVR age: odds ratio (OR) 7.7 (95% confidence interval [C

59 sis survival can be predicted based on first MVR age and prosthesis size.

60 had second MVR, prosthesis sizes were: first MVR 19+/-2 mm and second MVR 22+/-3 mm, and their body w

61 he 73 who did not have a second MVR on first-MVR demographic and perioperative variables.

62 Using first-MVR weight-matched controls, body weight increased simil

63 l LV torsional deformation acutely following MVR with and without chordal preservation.

64 Predictors of TE following MVR/DVR were raised mean platelet volume (4.0), raised f

65 0.001 for AVR and 44% vs. 4%, p = 0.0001 for MVR), and in patients > or =65 years after AVR, primary

66 years, 20+/-5% for repair versus 23+/-5% for MVR; P=0.4) or separately in PL-MVP (P=0.3) or AL-MVP (P

67 rial survival rates, 84% for AVR and 80% for MVR at 5 years, were not affected by VAI.

68 patients > or =60 to 65 years of age and for MVR in patients > or =65 to 70 years of age; in younger

69 Unadjusted operative mortality for MVR only was 5.60% for blacks versus 6.18% for whites (O

70 nd June 2001, 1,195 consecutive patients had MVR with ring annuloplasty.

71 However, MVR should be considered for high-risk patients and thos

72 Initial MVR and younger age were associated with worse survival.

73 Complications after initial MVR included heart block requiring pacemaker (16%), endo

74 , which included 102 survivors after initial MVR, was analyzed.

75 ority of deaths occurred early after initial MVR, with little late attrition despite repeat MVR and c

76 an interval of 4.8+/-3.8 years after initial MVR.

77 Age at initial MVR was 1.9+/-1.4 years.

78 ality was 4.7% overall and 1.4% for isolated MVR (1.1% for minimally invasive surgery vs. 1.6% for co

79 using minisatellite variant repeat mapping (MVR) by PCR to gain insight into allelic diversity and t

80 l dual-blade device; (2) microvitreoretinal (MVR) blade; and (3) Trabectome.

81 icant morphological predictors necessitating MVR were found.

82 y (a) morphological predictors necessitating MVR, and (b) predictors of future reoperation within the

83 At last follow-up, 82.7% of MVR patients had their arrhythmia controlled (69.1% not

84 over an extended period, but the dynamics of MVR at ribbon synapses is unknown.

85 n the synaptic cleft, a result indicative of MVR, and suggests that MVR can be modified by long-term

86 h current solutions and clinical outcomes of MVR with mitral valve allograft.

87 We find that the presence of MVR and receptor saturation at this synapse alters the c

88 These findings indicate that late results of MVR after minimally invasive surgery and after anterior

89 xible" patients required a repeat operation, MVR (1), and 2 patients required a transplant.

90 dels were developed: one for isolated AVR or MVR and one for CABG plus AVR or CABG plus MVR.

91 ications: prolonged ventilation after AVR or MVR, postoperative stay >14 days after AVR or MVR, reope

92 VR, postoperative stay >14 days after AVR or MVR, reoperation for bleeding after AVR, and postoperati

93 atients undergoing CABG combined with AVR or MVR.

94 ep sternal wound infection for either AVR or MVR.

95 en race and operative mortality after AVR or MVR.

96 redictor of operative mortality after AVR or MVR; however, black race was associated with an increase

97 of operative mortality after isolated AVR or MVR; however, there is evidence of an association betwee

98 f those patients who underwent either MVP or MVR between January 1, 1988, and December 31, 1998, for

99 ation rate was not different after repair or MVR overall (at 19 years, 20+/-5% for repair versus 23+/

100 free from failure of biventricular repair or MVR was 79% at 1 month and 55% at 5 years, with worse ou

101 scularization alone, mitral valve repair, or MVR.

102 minisatellite variant repeat mapping by PCR (MVR-PCR), which determines the distribution of variant r

103 A minisatellite variant repeat PCR (MVR-PCR) system gives Y-specific DNA codes, with a virtu

104 on >30% were randomized to receive CABG plus MVR (34 patients) or CABG only (39 patients).

105 of peak oxygen consumption in the CABG plus MVR group compared with the CABG group (3.3 mL/kg/min ve

106 in the secondary end points in the CABG plus MVR group compared with the CABG group: left ventricular

107 ps: 3% and 9%, respectively in the CABG plus MVR group, versus 3% (P=1.00) and 5% (P=0.66), respectiv

108 stay duration were greater in the CABG plus MVR group.

109 r MVR and one for CABG plus AVR or CABG plus MVR.

110 t closure and recovery from anesthesia, post-MVR data were acquired.

111 eformation (theta max) did not fall from pre-MVR values in the baseline state after the sham procedur

112 fluoroscopic marker images were obtained pre-MVR in the baseline state and with inotropic stimulation

113 eplacement without subvalvular preservation (MVR/NoSVP).

114 d replacement with subvalvular preservation (MVR/SVP), and 318 had replacement without subvalvular pr

115 ents undergoing mitral valve reconstruction (MVR) with either a flexible or nonflexible complete ring

116 ave a high degree of multivesicular release (MVR) in the absence of postsynaptic receptor saturation.

117 possibility is that multivesicular release (MVR) is determined by the instantaneous release probabil

118 Pronounced multivesicular release (MVR) occurs at the ribbon synapses of sensory neurones t

119 from univesicular to multivesicular release (MVR) when two Ca channels/AZ open at potentials above th

120 equency stimulation, multivesicular release (MVR), or asynchronous release can each activate NMDARs.

121 several vesicles, or multivesicular release (MVR), represents a simple mechanism to overcome the intr

122 ther it can increase multivesicular release (MVR).

123 vidual release site [multivesicular release (MVR)] and whether fusion of a single vesicle leads to re

124 f multiple vesicles (multivesicular release; MVR) from single active zones occurs at some central syn

125 The role of mitral valve repair (MVR) during coronary artery bypass grafting (CABG) in pa

126 R, with little late attrition despite repeat MVR and chronic anticoagulation.

127 nvestigated by Minisatellite Variant Repeat (MVR) analysis in a sample of >100 autochthonous individu

128 region using a minisatellite variant repeat (MVR)-PCR approach.

129 Using minisatellite variant repeat ("MVR") mapping, and compound haplotypes composed of the m

130 med in 46 patients (58%) and MV replacement (MVR) in 34.

131 placement (AVR) or mitral valve replacement (MVR) and from 43,463 patients undergoing CABG combined w

132 placement (AVR) or mitral valve replacement (MVR) at 13 VA medical centers were randomized to receive

133 atients undergoing mitral valve replacement (MVR) for chronic MR.

134 Mitral valve replacement (MVR) has a high mortality and morbidity.

135 al excision during mitral valve replacement (MVR) impairs left ventricular (LV) systolic function, bu

136 initial mechanical mitral valve replacement (MVR) in children <5 years of age are poorly defined.

137 s after prosthetic mitral valve replacement (MVR) in children aged <5 years are ill-defined and gener

138 nd to discuss when mitral valve replacement (MVR) may be favored over mitral valve repair.

139 ) and 482 isolated mitral valve replacement (MVR) operations with the St Jude Medical valve were stud

140 Early attempts at mitral valve replacement (MVR) with mitral valve allograft were unsuccessful mainl

141 ave suggested that mitral valve replacement (MVR) with sparing of the subvalvular apparatus had compa

142 plasty (SMVP), and mitral valve replacement (MVR), although the optimal therapeutic strategy is uncle

143 patients requiring mitral valve replacement (MVR), mechanical prostheses (MPs) have been reported to

144 ; the alternative, mitral valve replacement (MVR), necessitates commitment to future valve replacemen

145 ts with mechanical mitral valve replacement (MVR).

146 red after elective mitral valve replacement (MVR).

147 placement (AVR) or mitral valve replacement (MVR).

148 terioration (SVD) (mitral valve replacement [MVR] > AVR) and, therefore, for replacement of the PHV.

149 ue to MVP (679 repairs and 238 replacements [MVRs]) was performed between 1980 and 1995.

150 Myocardial vascular resistance (MVR) increased with increasing triglyceride levels (r=0.

151 F-MLI synapses but, while some showed robust MVR with increased release probability, most were limite

152 ctors for having a second MVR, the 29 second MVR survivors were compared with the 73 who did not have

153 Twenty-nine survivors had undergone a second MVR at an interval of 4.8+/-3.8 years after initial MVR.

154 mpared with the 73 who did not have a second MVR on first-MVR demographic and perioperative variables

155 y for patients <2 years old who had a second MVR versus those who did not.

156 To identify risk factors for having a second MVR, the 29 second MVR survivors were compared with the

157 s sizes were: first MVR 19+/-2 mm and second MVR 22+/-3 mm, and their body weight increased from 7.4+

158 is an increment in prosthesis size at second MVR, suggesting continued annular growth.

159 Reasons for second MVR were prosthetic valve stenosis 24 (83%), thrombosis

160 comparable regardless of the need for second MVR.

161 For those who had second MVR, prosthesis sizes were: first MVR 19+/-2 mm and seco

162 dren <5 years old despite the risk of second MVR in the youngest patients in whom the smallest prosth

163 however, differed significantly, with second MVR patients having smaller prostheses at first MVR (18.

164 ng with repeat 7, characteristic "signature" MVR patterns emerge for each common allele.

165 Sham operation and anterior chordal-sparing MVR did not affect regional LV torsion; however, loss of

166 Posterior chordal-sparing MVR impaired torsion only after calcium administration.

167 , and the chordae tendineac, chordal-sparing MVR is popular.

168 ure or anterior or posterior chordal-sparing MVR procedure (P > or = .10).

169 chordal excision (n = 7), or chordal-sparing MVR with preservation of the posterior leaflet and reatt

170 VR; however, after posterior chordal-sparing MVR, theta max fell in the lateral, posterior, and poste

171 ctive zones occurs at some central synapses, MVR is not thought to require coordination among release

172 ese results suggest that at PF-MLI synapses, MVR occurs under control conditions and is increased whe

173 when Pr is elevated by facilitation and that MVR may be a phenomenon common to many synapses througho

174 Based on these data, it is clear that MVR mapping is a very useful tool for the analysis of zo

175 These findings establish that MVR and postsynaptic receptor saturation can influence t

176 Furthermore, we show that MVR may occur under baseline physiological conditions, a

177 We suggest that MVR occurs at SC-CA1 synapses when Pr is elevated by fac

178 result indicative of MVR, and suggests that MVR can be modified by long-term plasticity.

179 The MVR blade exhibited minimal removal of TM and obvious in

180 P = NS) groups than the MVR/NoSVP group (5.0%).

181 P (66.2 +/- 12.4%, P = .017) groups than the MVR/NoSVP group (63.5 +/- 3.4%).

182 of complete heart block was noted within the MVR group (37.5%).

183 d complete mitral annuloplasty ring as their MVR procedure.

184 Of patients who did not undergo MVR or repeat CBC, 8% were in New York Heart Association

185 In elderly patients undergoing MVR, actuarial analysis overestimates the 10-year risk o

186 outcomes in infants and patients undergoing MVR, but has improved in our more recent experience.

187 eedom from VD in elderly patients undergoing MVR.

188 nts were subclassified into those undergoing MVR with chordal preservation (group Ia) and those under

189 preservation (group Ia) and those undergoing MVR with chordal transection (group Ib).

190 04 patients > or = 70 years of age underwent MVR at our institution.

191 lack and 46,249 white patients who underwent MVR alone or AVR alone from 1999 through 2002.

192 nsory synapses overcome this problem and use MVR to encode signals of widely varying intensities.

193 Using MVR-PCR, 20 to 25 repeats at the 5' end of the VNTR can

194 three different retinal synapses to utilize MVR.

195 eservation of the subvalvular apparatus with MVR has a theoretical advantage in terms of ventricular

196 tion techniques are used in combination with MVR.

197 ue to MVP, mitral valve repair compared with MVR provides improved very long-term survival after surg

198 oved left ventricular function compared with MVR.

199 Patients with MVR had larger atria (p < 0.0001), lower left ventricula

200 he role of ablative therapy in patients with MVR is not yet established, with safety concerns and ver

201 cember 2008, we followed up 81 patients with MVR undergoing first-time AF ablation (compared with 162

202 ation is feasible and safe for patients with MVR.

203 7-year event-free survival (survival without MVR or repeat CBC) was 80 +/- 4%, 77 +/- 4%, 65 +/- 6%,