コーパス検索結果 (1語後でソート)
通し番号をクリックするとPubMedの該当ページを表示します
3 uman monoclonal antibody that binds to human mucosal addressin cell adhesion molecule-1 (MAdCAM-1) to
5 nza HA and GPI-anchored CCL28 as antigen and mucosal adjuvant, respectively, when immunized intranasa
7 on-obese diabetic (NOD) mouse model reported mucosal administration of T1D-related autoantigens [proi
10 ved mast cells were used as "surrogates" for mucosal and connective tissue mast cells, respectively,
13 ggests abnormal macrophage switching in both mucosal and luminal areas of COPD patients, that strongl
15 ase in expression of CCL27, one of the major mucosal and skin cytokines, was found that correlated wi
16 complex interplay of the epithelial barrier, mucosal and systemic immune response, route of exposure,
19 pitope specificities, locations (systemic or mucosal), and effector functions of antibodies elicited
20 th were assessed including periodontal, oral mucosal, and caries status in Eastern Finland from 2014
22 respective of not significantly boosting the mucosal antibody response, it augmented the frequency of
23 -anchored CCL28 induces significantly higher mucosal antibody responses, involved in providing long-t
24 Analysis revealed that all animals exhibited mucosal antigen-specific IgG and IgA with the IgA respon
29 tially affected NK, NKT (invariant NKT), and mucosal-associated invariant T cell populations in a dos
30 ng to significantly increased frequencies of mucosal-associated invariant T cells 6 mo postinfection.
31 iboflavin- and folate-related metabolites to mucosal-associated invariant T cells, but it is unknown
32 ntranasal vaccines, which deliver antigen to mucosal-associated lymphoid tissue and aim to elicit pro
33 nflammation is associated with low levels of mucosal ATP, highlighting the importance of mitochondria
35 y CD8(+) T cells could impair the intestinal mucosal barrier already in the seronegative phase of acu
36 ighlight research trends at this distinctive mucosal barrier and identify crucial gaps in our current
37 signaling events activated by a compromised mucosal barrier and provide a novel in vivo screening pl
38 nce between these signaling pathways and key mucosal barrier components in regulating colon tumorigen
39 The cytokine IL-22 plays a critical role in mucosal barrier defense, but the mechanisms that promote
44 composition of the fecal microbiota, reduced mucosal barrier function, and altered epithelial prolife
47 functions of IELs in the maintenance of the mucosal barrier integrity, as well as how dysregulated I
48 untered by Shigella upon its crossing of the mucosal barrier, are also mainly targeted by injection-o
49 re, we show that loss of PGANT4 disrupts the mucosal barrier, resulting in epithelial expression of t
51 l transepithelial migration utilizing airway mucosal barriers differentiated from primary human airwa
54 nd postintervention stool samples and rectal mucosal biopsies were collected and used to quantify cal
55 healthy subjects); 232 fecal samples and 59 mucosal biopsy samples were collected and analyzed by 16
56 r an acute response (luminal obstruction and mucosal blanching); 2 other patients had a delayed wheal
57 ycle immunodeficiency virus, followed by two mucosal boosts with either recombinant adenovirus (rAd)
59 d as yet unresolved, question is whether the mucosal bottleneck selects for viruses with increased tr
61 To dissect the role of neutrophils during mucosal candidiasis, we took advantage of a new, transpa
65 g HIV and had increased numbers of activated mucosal CD4(+) T cells compared to those with Lactobacil
67 In vivo, poly(I.C)-induced neutrophilia and mucosal chemokine production are blocked by a small-mole
68 ha-defective strains attained high levels of mucosal colonization but failed to induce robust vaginal
69 erienced severe disease, including increased mucosal colonization by C. rodentium, prolonged pathogen
70 anisms required for GBS to transition from a mucosal commensal lifestyle to bloodstream invasion, we
76 roperties in parallel with analysis of local mucosal cytokine responses induced by nasal allergen exp
78 ing MCs were associated with the severity of mucosal damage, and their numbers were increased in pati
81 duced increases in gut permeability, colonic mucosal destruction, and colonic IL-1beta expression.
82 paranasal sinuses was performed to look for mucosal disease of the paranasal sinuses, drainage pathw
85 1 in the ileum, those lacking Mdr1 displayed mucosal dysfunction and induced Crohn's disease-like ile
87 anisms underlying disease progression on all mucosal epithelia, including those in the mouth, lungs,
90 co-culture system consisting of a polarized mucosal epithelium and human neutrophils can provide a v
91 barrier, including increased permeability of mucosal epithelium and reduced production of important a
92 -ILK-dependent inflammatory signaling in the mucosal epithelium can be therapeutically targeted by th
93 amily, was used to infect equine respiratory mucosal explants and primary equine respiratory epitheli
96 those with colon-only CD based on increased mucosal expression of genes that mediate type 2 and type
97 th Crohn's disease and leprosy and implicate mucosal factors and the innate immune response to microb
98 at the modified preserved nasal and lacrimal mucosal flap technique in EES-DCR for treating PANDO is
101 fficient technique facilitating ocular, oral mucosal, gastrointestinal, ungual and vaginal drug admin
104 re present in 16.3% of patients with IBD and mucosal healing (15.4% of patients with CD, 17.4% with U
107 n this cutoff, 36.2% of patients with IBD in mucosal healing have increased intestinal permeability.
108 ures of inflammatory bowel disease, complete mucosal healing occurs in fewer than 50% of patients.
109 eability in patients with symptomatic IBD in mucosal healing vs patients with asymptomatic IBD in muc
111 oing bowel symptoms in patients with IBD and mucosal healing with 95.2% sensitivity and 97.6% specifi
112 stinal permeability in patients with IBD and mucosal healing, we associated impaired intestinal perme
114 t; at day 0, after reinstitution of gingival/mucosal health; at days 7, 14, and 21, during stent-medi
116 ese gut bacteria, fungi, and viruses mediate mucosal homeostasis via their composite genes (metagenom
120 esolution of inflammation and contributes to mucosal host defense of the nasopharyngeal niche, a rese
124 o define type 2 inflammation based on airway mucosal IL-13-driven gene expression and how this relate
127 ry 'dipstick' tests to assess non-accessible mucosal immune development and identify early precursors
129 es, avidities, and functions of systemic and mucosal immune responses elicited by a vaccine regimen c
134 malian gastrointestinal tract and associated mucosal immune system harbor a large repertoire of metab
135 ternal environment; however, the role of the mucosal immune system in chronic lung diseases is incomp
140 ation promotes competent innate and acquired mucosal immune systems, epithelial renewal, barrier inte
141 than inactivated vaccines by eliciting local mucosal immunity and systemic B cell- and T cell-mediate
144 ent for IgA nephropathy targeting intestinal mucosal immunity upstream of disease manifestation.
145 nature of antipneumococcal antibody-mediated mucosal immunity while informing vaccine development.
149 malonate, phenylacetylglycine, alanine) and mucosal immunoglobulin (IgM) and cytokine (IL-10, IL-4)
150 ssed the impact of the genital microbiota on mucosal immunology in ACB women and microbiome-HSV-2 int
154 (grade 3 acne [n=1] and intolerable grade 2 mucosal inflammation [n=1]); hence, doses of 200 mg and
155 During Salmonella-induced gastroenteritis, mucosal inflammation creates a niche that favors the exp
156 r study of the role of RNASET2 in regulating mucosal inflammation may lead to development of novel th
158 Allergic rhinitis (AR) is characterized by mucosal inflammation, driven by activated immune cells.
159 r a specific parasite protein that increases mucosal inflammation, expands our knowledge of host-para
160 environment in pathological processes, like mucosal inflammation, preneoplasia, and neoplasia, altho
167 -10 was rapidly induced following intestinal mucosal injury and was required for optimal intestinal m
168 histologic evidence of significant duodenal mucosal injury, latiglutenase did not improve histologic
172 superficial wounds in the colon and impaired mucosal innate immune responses against C. rodentium inf
173 activity arising from acid-sensitive general mucosal innervation by comparing acid-evoked c-Fos in wi
174 iceptors, suggesting that trigeminal general mucosal innervation carries information about acids in t
175 l and glossopharyngeal nerves, while general mucosal innervation is carried by the trigeminal and glo
176 We observe that EMT silences protective mucosal interferon (IFN)-I and III production associated
178 erently in SI; Mf3 formed a dense network in mucosal lamina propria, whereas Mf4 was enriched in subm
180 part of the host diet, lining the intestinal mucosal layer, and decorating the surface of other micro
181 aniasis (LCL), which heals spontaneously, or mucosal leishmaniasis (ML), characterized by chronic and
182 of teeth, dental plaque, or detectable oral mucosal lesions and PD risk, although there was a sugges
183 points were the change in the mean number of mucosal lesions and the number of subjects with large er
184 t role of C. difficile flagella in eliciting mucosal lesions as long as the toxins exert their action
185 estive association with Candida-related oral mucosal lesions in males (hazard ratio = 1.56, 95% CI: 0
186 Active EPIT significantly reduced gastric mucosal lesions induced by PPE oral intake (macroscopic
187 ramural nodules, continuous or discontinuous mucosal lining and cholelithiasis may indicate XGC rathe
191 ng a transparent juvenile zebrafish to model mucosal lung infection and show that C. albicans and P.
194 lone, and although the activity was lower in mucosal melanoma, the safety profile was similar between
198 ucoadhesion between polymeric substances and mucosal membranes, widely exploited in the pharmaceutics
201 The 10% CP dietary treatment damaged ileal mucosal morphology, and decreased the expression of biom
202 binant gluten-targeting proteases, to reduce mucosal morphometric measures in biopsy specimens from p
207 cted to be a valuable model for the study of mucosal papillomavirus disease, progression, and host im
215 termine if the same macaques maintained high mucosal plasma cell frequencies postinfection and if thi
216 l and contrast the potential contribution of mucosal plasma cells to mediate protection at sites of i
219 hypothesis that smoking increases bronchial mucosal production of IL-17A which acts on bronchial epi
221 Bone marrow (BM) chimera mice revealed that mucosal repair depended on TNF production by BM-derived
225 LC-DG and its PB attenuate the inflammatory mucosal response in an ex-vivo organ culture model of PI
228 is a risk of Zika virus transmission via the mucosal route, but that the risk posed by oral secretion
229 e exposed white-tailed deer to CWD prions by mucosal routes and performed serial necropsies to assess
230 LC2 numbers significantly increased in nasal mucosal samples and decreased in blood at the time of CO
232 type 17 immune response (IL17A and IL23) in mucosal samples from patients with UC compared with pati
236 tivation of Vgamma9/Vdelta2 T cells promoted mucosal secretion of IL-22 and ICOSL/TNF-alpha-dependent
241 ymphocytes and T cell subsets in lymphoid or mucosal sites did not vary with clinical state, and was
242 es but developed persistent infection at the mucosal sites including those of the anogenital region a
244 whereas it arises in internal body surfaces (mucosal sites) and on the hands and feet (acral sites) i
245 id arthritis (RA), immunological triggers at mucosal sites, such as the gut microbiota, may promote a
246 to play an important role in host defense at mucosal sites, where it prevents invasion of pathogens b
248 may be to promote immune cell persistence at mucosal sites.Our study identifies a new regulator of IF
249 chenoid esophagitis may cause ulceration and mucosal sloughing severe enough to result in massive upp
250 rity of lesions were found in the pharyngeal mucosal space (n=16) with squamous cell carcinoma being
252 tionship between secretory IgA (SIgA) on the mucosal surface of small airways and parameters of infla
253 role in protective immunity to infection at mucosal surface, but also mediate pathology in certain a
254 ave long been implicated in virulence at the mucosal surface, including contributions to colonization
255 a protein vaccine formulation to the vaginal mucosal surface, we used a novel vaginal ring device com
258 defined by an increased ability to adhere to mucosal surfaces and a decreased ability to cause diseas
259 s way readily discriminate between different mucosal surfaces and display the ability to characterize
260 ical degradation in the harsh environment of mucosal surfaces and enzymes of host or microbial origin
266 trillions of microorganisms inhabiting human mucosal surfaces participate intricately in local homeos
267 is important for homeostasis in organs with mucosal surfaces that interface with the external enviro
268 tal zoonosis acquired by contact of skin and mucosal surfaces with soil and water contaminated with i
269 mbers of the microbiomes found on nearly all mucosal surfaces, and interest is growing in understandi
270 establish tolerance, prevent inflammation at mucosal surfaces, and regulate immunopathology during in
273 t of Tr1 cells in various organs, and in the mucosal system during parasitic and viral infections.
277 ntibody blocking of HIV-1 acquisition within mucosal tissue may prove critical to effective vaccine d
279 respective study drug was injected into the mucosal tissue surrounding the surgical site prior to su
281 t distribution, maturation, and migration in mucosal tissues (lungs, intestines), associated lymph no
282 with decreased expression in peripheral and mucosal tissues and DNA hypermethylation in CD patients
283 ld (M) cells are epithelial cells present in mucosal tissues and specialized for the capture of lumin
284 knockout not only decreased Cdc42 levels in mucosal tissues, but it also inhibited repair of damaged
285 immunoregulatory lectin widely expressed in mucosal tissues, contributes to Y. enterocolitica pathog
286 n-specific CD8(+) T cells that accumulate in mucosal tissues, including the female genital and respir
291 h a reduced gut microbiota diversity and low mucosal total IgA levels in infancy have been associated
292 tralizing antibodies (nnAbs) may also impact mucosal transmission events through Fc-gamma receptor (F
294 sease Activity Index (CDAI) of 220-450, with mucosal ulcers in the ileum or colon, or both, and a Cro
295 These findings highlight the efficacy of mucosal vaccination via this attenuated strain and will
298 tertiary lymphoid organs present within the mucosal wall, along with other lymphatic diseases, such
WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。