ライフサイエンスコーパス: Mycobacterium leprae

1 logy with Mn-superoxide dismutase of MAC and Mycobacterium leprae.

2 tro, monocytes produced IL-18 in response to Mycobacterium leprae.

3 associated with active cellular immunity to Mycobacterium leprae.

4 man pathogens Mycobacterium tuberculosis and Mycobacterium leprae.

5 atients, who have potent T cell responses to Mycobacterium leprae.

6 e-rich antigens found in M. tuberculosis and Mycobacterium leprae.

7 libraries of Mycobacterium tuberculosis and Mycobacterium leprae.

8 to be Mycobacterium lepromatosis instead of Mycobacterium leprae.

9 cells by an intracellular bacterial pathogen Mycobacterium leprae.

10 predicted for Mycobacterium tuberculosis and Mycobacterium leprae.

11 ux pump in all sequenced mycobacteria except Mycobacterium leprae.

12 eprosy, an intracellular infection caused by Mycobacterium leprae.

13 in Mexico, wild armadillos are infected with Mycobacterium leprae.

14 disease caused by the intracellular pathogen Mycobacterium leprae.

15 Leprosy is caused by infection with Mycobacterium leprae.

16 gy and immune responses that fail to control Mycobacterium leprae.

17 ses including infection with leprosy-causing Mycobacterium leprae.

18 proteins are conserved within the genome of Mycobacterium leprae.

19 h the type of immune response mounted toward Mycobacterium leprae.

20 cellular parasites Rickettsia prowazekii and Mycobacterium leprae.

21 aired mitogenesis in response to antigens of Mycobacterium leprae.

22 open reading frame in a homologous operon in Mycobacterium leprae (11-12% identity).

23 ising the N-terminal portion of the putative Mycobacterium leprae 19-kDa lipoprotein, triggered an in

24 The 10-kDa protein Ag of Mycobacterium leprae, a human GroES hsp10 cognate, is a

25 Mycobacterium leprae, a major human pathogen, grows poor

26 egments revealed significant divergence from Mycobacterium leprae, a well-known cause of leprosy, tha

27 possible to distinguish different strains of Mycobacterium leprae according to their genetic sequence

28 Of these, 2 had dapsone-resistant Mycobacterium leprae and 1 of these patients also had ri

29 /nu) mice were infected in the footpads with Mycobacterium leprae and fed a linoleic acid-free diet.

30 ns is largely determined by host immunity to Mycobacterium leprae and is a model for immunoregulation

31 ther mycobacterial species tested, including Mycobacterium leprae and Mycobacterium avium.

32 Comparison of ancient and modern genomes of Mycobacterium leprae and Mycobacterium tuberculosis give

33 overall) and is 50% identical to FAP of both Mycobacterium leprae and Mycobacterium tuberculosis.

34 cross-reactivity of ESAT6 and CFP10 between Mycobacterium leprae and Mycobacterium tuberculosis.

35 of the S. coelicolor subunit and those from Mycobacterium leprae and Mycoplasma genitalium.

36 een shown to recognize specifically LAM from Mycobacterium leprae and not from M. tuberculosis Erdman

37 lar bacterial pathogens in humans, including Mycobacterium leprae and Salmonella enterica serovar Typ

38 lysis to identify genes that are specific to Mycobacterium leprae and tested both recombinant protein

39 gated the role of TLRs in the recognition of Mycobacterium leprae and the significance of TLR2Arg(677

40 Sputum PCR testing revealed Mycobacterium leprae, and a fine-needle aspirate of the

41 tions in codon 53 or 55 of the folP1 gene of Mycobacterium leprae, and definitive evidence linking th

42 hese species and in Mycobacterium bovis BCG, Mycobacterium leprae, and Mycobacterium fortuitum.

43 Several Mycobacterium tuberculosis strains, Mycobacterium leprae, and other mycobacterial pathogens

44 ll wall layer of Mycobacterium tuberculosis, Mycobacterium leprae, and several opportunistic mycobact

45 Fractionated Mycobacterium leprae antigens containing cell wall prote

46 We recently identified several Mycobacterium leprae antigens that stimulate gamma inter

47 Long SSRs in Mycobacterium leprae are mostly associated with pseudoge

48 resistance surveillance and strain typing of Mycobacterium leprae are necessary to investigate ongoin

49 plied to the obligate intracellular organism Mycobacterium leprae because of the difficulty of obtain

50 or/interleukin-10 ratio when stimulated with Mycobacterium leprae but not with lipopolysaccharide or

51 ctional homology of the Nramp homologue from Mycobacterium leprae by using a yeast complementation as

52 Mycobacterium leprae, by infecting Schwann cells, contri

53 Mycobacterium leprae causes leprosy and is unique among

54 rkers to induce cellular immune responses to Mycobacterium leprae: CD1a mediates the presentation of

55 lenge in animal models, for efficacy against Mycobacterium leprae challenge in a murine model of lepr

56 Leprosy, caused by Mycobacterium leprae continues to afflict millions.

57 The crystal structure of the Mycobacterium leprae cpn10 (Ml-cpn10) oligomer has been

58 ng pathogen-associated molecular patterns of Mycobacterium leprae, cytokine release by innate immune

59 sis and then therapeutically vaccinated with Mycobacterium leprae-derived hsp65 DNA develop severe gr

60 Mycobacterium leprae DNA was detected through quantitati

61 xperimental leprosy, both low- and high-dose Mycobacterium leprae foot pad (FP) infections were evalu

62 ple sequence repeats, or microsatellites, in Mycobacterium leprae from patients living in and around

63 NA sequence analysis of cosmid L373 from the Mycobacterium leprae genome, an open reading frame of 1.

64 odel for the accretion of pseudogenes in the Mycobacterium leprae genome, triggered by the loss of di

65 n in animals and cultures, the cell walls of Mycobacterium leprae grown in armadillos was characteriz

66 A DNA vaccine encoding the hsp60 molecule of Mycobacterium leprae has previously been shown to protec

67 Mycobacterium leprae has the capacity to invade the peri

68 ifloxacin, and assessed the potential of the Mycobacterium leprae heat shock protein-65 DNA vaccine t

69 The sequence of the Mycobacterium leprae homologue of CFP-10 shows only 40%

70 The sequence of the Mycobacterium leprae homologue of ESAT-6 shows only 36%

71 A Mycobacterium leprae homologue of mysB and mtu sigB was

72 We previously showed that Mycobacterium leprae HSP65 prevented development of airw

73 loped an in vitro model to study the fate of Mycobacterium leprae in a LL lesion, with and without im

74 gle nucleotide polymorphism (SNP) typing for Mycobacterium leprae in biopsied skin lesion samples.

75 unit of the phenolic glycolipid-1 (PGL-1) of Mycobacterium leprae in determining the bacterial predil

76 f IL-12Rbeta2 on T cells was up-regulated by Mycobacterium leprae in tuberculoid but not in lepromato

77 antimicrobial activity against the pathogen Mycobacterium leprae in vitro.

78 ctivate T cells that recognize the pathogen, Mycobacterium leprae, in a langerin-dependent manner.

79 , with the exception of the peptidoglycan of Mycobacterium leprae, in which glycine replaces the L-al

80 Primary transmission of drug-resistant Mycobacterium leprae, including a rifampicin-resistant s

81 e degenerate genome of the leprosy bacillus, Mycobacterium leprae, indicating that non-essential func

82 In vitro, Mycobacterium leprae induced IL-15 secretion from periph

83 -lep lesions, hsa-mir-21, was upregulated in Mycobacterium leprae-infected monocytes.

84 Herein, a global gene expression profile of Mycobacterium leprae-infected primary human Schwann cell

85 How Mycobacterium leprae infection causes demyelination to m

86 Early diagnosis of Mycobacterium leprae infection should therefore be empha

87 Mycobacterium leprae infection was evaluated in interfer

88 Nerve damage is the hallmark of Mycobacterium leprae infection, which results from M. le

89 esulting in disabilities as a consequence of Mycobacterium leprae infection.

90 the molecular basis of the neural tropism of Mycobacterium leprae is attributable to the specific bin

91 To understand how the immune response to Mycobacterium leprae is regulated, human dendritic cells

92 Mycobacterium leprae is the noncultivable pathogen of le

93 role played by apoptosis in host response to Mycobacterium leprae is unclear.

94 rosy, a chronic infectious disease caused by Mycobacterium leprae, is prevalent in India, where about

95 1990s, transmission of the causative agent, Mycobacterium leprae, is still occurring, and new cases

96 In the peptidoglycan of Mycobacterium leprae, L-alanine of the side chain is rep

97 matory cytokines by ENL PBMCs in response to Mycobacterium leprae lysate.

98 atis and like Mycobacterium tuberculosis and Mycobacterium leprae, M. marinum was shown to possess a

99 d two other crystal structures for RuvA from Mycobacterium leprae (MleRuvA) and EcoRuvA showed that i

100 smegmatis with the homologous sequences from Mycobacterium leprae, Mycobacterium bovis, and Mycobacte

101 of leprosy, attributed to early invasion by Mycobacterium leprae of Schwann cells related to unmyeli

102 wing exposure to Mycobacterium tuberculosis, Mycobacterium leprae or Mycobacterium avium is correlate

103 Leprosy, caused by infection with Mycobacterium leprae or the recently discovered Mycobact

104 cognize lipid Ags from the leprosy pathogen, Mycobacterium leprae, or the related species, Mycobacter

105 terium tuberculosis, Mycobacterium bovis, or Mycobacterium leprae; or in the non-mycobacterial Actino

106 Accordingly, comparative bioinformatics and Mycobacterium leprae protein microarrays were applied to

107 d demyelination and axonal injury induced by Mycobacterium leprae provides a model for elucidating th

108 n to both CD1b- and MHC class II-restricted, Mycobacterium leprae-reactive T cells derived from lepro

109 We identified three CD4+ Mycobacterium leprae-reactive, CD1-restricted T cell lin

110 riation by neutron scattering was applied to Mycobacterium leprae RuvA (MleRuvA), a synthetic analogu

111 The Mycobacterium leprae RuvA homologue (MlRuvA) was over-ex

112 ilarity to the enzyme from cyanobacteria and Mycobacterium leprae, similarity to the conserved transa

113 d lateral flow assays (LFA) for detection of Mycobacterium leprae-specific antibodies: the visual imm

114 To identify Mycobacterium leprae-specific human T-cell epitopes, whi

115 Mycobacterium leprae specifically bound to alpha-DG only

116 In response to Mycobacterium leprae stimulation, IFN-gamma differential

117 treatment with five different microbial hsp (Mycobacterium leprae, Streptococcus pneumoniae, Helicoba

118 reased incidence of leprosy, suggesting that Mycobacterium leprae subverts the TLR system as a mechan

119 conserved in Mycobacterium tuberculosis and Mycobacterium leprae, suggesting that regulation of DNA

120 In disease due to Mycobacterium leprae, Th2 cells predominate in tissue le

121 to investigate the molecular epidemiology of Mycobacterium leprae, the causative agent of leprosy, du

122 Mycobacterium leprae, the causative agent of leprosy, is

123 tect leprosy and to stop the transmission of Mycobacterium leprae, the causative bacillus of the dise

124 Mycobacterium leprae, the causative organism of leprosy,

125 wann cell response to long-term infection of Mycobacterium leprae, the causative organism of leprosy,

126 Mycobacterium leprae, the causative organism of leprosy,

127 hown to serve as a Schwann cell receptor for Mycobacterium leprae, the causative organism of leprosy.

128 ates, as with the worldwide dissemination of Mycobacterium leprae, the cause of leprosy.

129 Infection of peripheral nerve by Mycobacterium leprae, the histopathological hallmark of

130 ing treatment of monocytes with IFN-beta and Mycobacterium leprae, the intracellular bacterium that c

131 Mycobacterium leprae, the intracellular etiological agen

132 tools for the differentiation of isolates of Mycobacterium leprae, the organism that causes leprosy,

133 ng characteristics of the causative bacillus Mycobacterium leprae: the long incubation period, limite

134 xide stress response in enteric bacteria) in Mycobacterium leprae, this gene is inactive in all strai

135 six new proteins isolated from in vivo-grown Mycobacterium leprae, three of which correspond to produ

136 idermal LCs presented nonpeptide antigens of Mycobacterium leprae to T cell clones derived from a lep

137 the species-specific phenolic glycolipid of Mycobacterium leprae triggers uptake into Schwann cells

138 DNA from Mycobacterium leprae was amplified from all nine skeleto

139 idoglycan from in vivo-derived noncultivable Mycobacterium leprae was assumed to possess the basic st

140 otide sequence of 1.5 Mb of genomic DNA from Mycobacterium leprae was determined using computer-assis

141 PBMC of tuberculoid patients stimulated with Mycobacterium leprae was partially inhibited by mAbs to

142 ganization of TrxR and Trx has been found in Mycobacterium leprae, where TrxR and Trx are encoded by

143 Mycobacterium leprae, which causes leprosy, grows optima

144 f human leprosy, yet it is not clear whether Mycobacterium leprae, which has a distinct MDP structure

145 exican patient, and compared it with that of Mycobacterium leprae, which has undergone extensive redu

146 sy is a chronic infectious disease caused by Mycobacterium leprae, which primarily infects macrophage

147 me sequences of certain pathogenic bacteria (Mycobacterium leprae, Yersinia pestis and Rickettsia pro