ライフサイエンスコーパス: N-acetylglucosamine

1 osidic linkages of N-acetylgalactosamine and N-acetylglucosamine.

2 etic reactions involving uridine diphosphate N-acetylglucosamine.

3 e (OGT) modifies intracellular proteins with N-acetylglucosamine.

4 nnose, alpha-glucose, beta-glucose, and beta-N-acetylglucosamine.

5 or instantaneous reaction with substrate UDP-N-acetylglucosamine.

6 o increased binding capacity of ficolin-2 to N-acetylglucosamine.

7 glucosamine (neosamine) series prepared from N-acetylglucosamine.

8 as well as UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine.

9 , lipoprotein YceK, toxin HicA, or MurA (UDP-N-acetylglucosamine 1-carboxyvinyltransferase) suppresse

10 iotic identified two signaling muropeptides (N-acetylglucosamine-1,6-anhydro-N-acetylmuramyl pentapep

11 UDP-GlcNAc biosynthesis, converting UTP and N-acetylglucosamine-1-phosphate (GlcNAc-1P) to UDP-GlcNA

12 Eight N-acetylglucosamine-1-phosphate and N-acetylgalactosamin

13 onstruction of a defined mutation in the UDP-N-acetylglucosamine-1-phosphate transferase gene, wecA,

14 onstruction of a defined mutation in the UDP-N-acetylglucosamine-1-phosphate transferase gene, wecA,

15 ical and chemoenzymatic syntheses relying on N-acetylglucosamine-1-phosphate uridylyltransferase (Glm

16 in the mammalian transmembrane glycoprotein N-acetylglucosamine-1-phosphodiester alpha-N-acetylgluco

17 UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (GlcNAc-1-phosp

18 beta subunits of UDP-GlcNAc:lysosomal enzyme N-acetylglucosamine-1-phosphotransferase (phosphotransfe

19 The Golgi-resident N-acetylglucosamine-1-phosphotransferase (PT) complex is

20 ngineered to carry a mutation in the Gnptab (N-acetylglucosamine-1-phosphotransferase subunits alpha/

21 lysosomal storage disorder caused by loss of N-acetylglucosamine-1-phosphotransferase, which tags lys

22 -phosphate uridylyltransferase (galU), a UDP-N-acetylglucosamine 2-epimerase (wecB) and a UDP-N-acety

23 e protein with key enzymatic activities, UDP-N-acetylglucosamine 2-epimerase and N-acetylmannosamine

24 Using UDP-N-acetylglucosamine 2-epimerase/N-acetylmannosamine kina

25 the key enzyme of sialic acid biosynthesis, N-acetylglucosamine 2-epimerase/N-acetylmannosamine kina

26 d paucimannosylation (mannose(1-3)fucose(0-1)N-acetylglucosamine(2)Asn).

27 hesis of sialic acid is the bifunctional UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kina

28 acetylmannosamine kinase (MNK) domain of UDP-N-acetylglucosamine-2-epimerase/N-acetylmannosamine kina

29 ate (UDP)-sugar donors, UDP-4-deoxy-4-fluoro-N-acetylglucosamine (4FGlcNAc) and UDP-4-deoxy-4-fluoro-

30 Sulf1 codes for an N-acetylglucosamine 6-O-endosulfatase, an enzyme that sp

31 Mice deficient in N-acetylglucosamine-6-O-sulfotransferase-1 (GlcNAc6ST-1)

32 nuclear cells and identified 2 autoantigens, N-acetylglucosamine-6-sulfatase (GNS) and filamin A (FLN

33 Uridine diphospho-N-acetylglucosamine, a product of the hexosamine synthet

34 UDP-N-acetylglucosamine acyltransferase (LpxA) and UDP-3-O-(

35 UDP-N-acetylglucosamine acyltransferase (LpxA) and UDP-3-O-(

36 rease of the structures containing bisecting N-acetylglucosamine along with bi- and trisialylated tri

37 ent resulting in IgG molecules with only one N-acetylglucosamine and a fucose residue was fully able

38 en the C6 and C1 hydroxyl groups of mannose, N-acetylglucosamine and glucose respectively.

39 C in a ligand-free form, in complex with the N-acetylglucosamine and N-acetylgalactosamine products o

40 These structures showed N-acetylglucosamine and N-acetylgalactosamine to be reco

41 in to catalyze the in vitro incorporation of N-acetylglucosamine and N-acetylgalactosamine to oligosa

42 ration-dependent manner and was inhibited by N-acetylglucosamine and N-acetylgalactosamine.

43 typical M. xanthus lipids, fucose, mannose, N-acetylglucosamine and N-acetylgalactoseamine carbohydr

44 ure glycosylation form, with high amounts of N-acetylglucosamine and sialic acid.

45 all producing an identical polymer from UDP-N-acetylglucosamine and UDP-glucuronic acid.

46 nT2 able to utilize both uridine diphosphate N-acetylglucosamine and uridine diphosphate N-acetylgala

47 ng cell wall precursors, UDP-Glucose and UDP-N-acetylglucosamine are efficiently used to initiate tra

48 tone O-GlcNAcylation (O-GlcNAc=O-linked beta-N-acetylglucosamine) are largely unexplored.

49 use cytoplasmic UDP-glucuronic acid and UDP-N-acetylglucosamine as substrates.

50 f successive coupled enzyme assays using UDP-n-acetylglucosamine as the initial sugar substrate.

51 Similar to alginate and poly-beta-1,6 N-acetylglucosamine, bacterial cellulose is implicated i

52 nsfer of GalNAc to the simple sugar acceptor N-acetylglucosamine-beta-p-nitrophenol (GlcNAcbeta-pNP)

53 l trisaccharide [N-acetylgalactosamine-beta3-N-acetylglucosamine-beta4-(phosphate-6-)mannose] is requ

54 ty to the GalFuc-binding lectin CGL2 and the N-acetylglucosamine-binding lectin XCL, the mutant was r

55 flagellar and type III secretion systems and N-acetylglucosamine-binding protein GpbA while inducing

56 smembrane protein, as well as spermidine and N-acetylglucosamine biosynthesis, all contribute to sura

57 mutation using both the UDP-glucose and UDP-N-acetylglucosamine bound structures of the wild-type pr

58 eptor endocytosis and signaling by promoting N-acetylglucosamine branching of Asn (N)-linked glycans.

59 n of uridyldiphospho-3-O-(R-hydroxydecanoyl)-N-acetylglucosamine by the enzyme LpxC.

60 A fluoro-tagged N-acetylglucosamine-capped glycolipid that can form lipi

61 l for receptor function, and elongation with N-acetylglucosamine, catalyzed by members of the Fringe

62 Inhibition of hexokinase by N-acetylglucosamine causes its dissociation from mitocho

63 measured by the incorporation of the [(14)C]N-acetylglucosamine cell wall precursor.

64 f et al. (2016) report that detection of the N-acetylglucosamine component of peptidoglycan by the gl

65 hile the UT-A1 in lipid rafts was the mature N-acetylglucosamine-containing form, as detected by whea

66 ains confer recognitional specificity toward N-acetylglucosamine-containing signaling molecules, such

67 Exposure to bacteria or their N-acetylglucosamine-containing surface polysaccharides,

68 inhibitor of UDP-3-O-(R-3-hydroxymyristoyl)-N-acetylglucosamine deacetylase (LpxC) in Gram-negative

69 s made of repeating N-acetylmuramic acid and N-acetylglucosamine disaccharides cross-linked by pentap

70 iosynthetic pathway (HBSP) that produces UDP-N-acetylglucosamine for O-linked N-acetylglucosamine mod

71 OGT catalyses the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine (UDP-Gl

72 the pools of UDP-glucose, UDP-galactose, UDP-N-acetylglucosamine, GDP-mannose, and GDP-fucose in Plas

73 nthase 1-3 (HAS1-3) isoenzymes that transfer N-acetylglucosamine (GlcNAc) and glucuronic acid (GlcUA)

74 t sugar-aromatic interactions, with glucose, N-acetylglucosamine (GlcNAc) and mannose in between.

75 oglycan (PGN) consists of repeating units of N-acetylglucosamine (GlcNAc) and N-acetylmuramic acid (M

76 tion of nucleocytoplasmic proteins with beta-N-acetylglucosamine (GlcNAc) and regulates numerous biol

77 in particular with higher levels of beta-1,6-N-acetylglucosamine (GlcNAc) branched N-glycans.

78 tion is altered by deleting two Bdellovibrio N-acetylglucosamine (GlcNAc) deacetylases, one of which

79 The sugar N-acetylglucosamine (GlcNAc) enhances N-glycan branching

80 N-acetylglucosamine (GlcNAc) exists ubiquitously as a co

81 diate addition and removal, respectively, of N-acetylglucosamine (GlcNAc) from intracellular protein

82 O-GlcNAc transferase (OGT), which transfers N-acetylglucosamine (GlcNAc) from the nucleotide sugar d

83 ow outstanding affinities for derivatives of N-acetylglucosamine (GlcNAc) in aqueous solution.

84 e (OGT) mediates post-translational O-linked N-acetylglucosamine (GlcNAc) modification.

85 iously that varphi11 requires alpha- or beta-N-acetylglucosamine (GlcNAc) moieties on cell wall teich

86 erase that mediates the O-linked addition of N-acetylglucosamine (GlcNAc) moieties to Ser and Thr res

87 c proteins via O-linked addition of a single N-acetylglucosamine (GlcNAc) moiety.

88 described here, is attached to the remaining N-acetylglucosamine (GlcNAc) of IgG, using a mutant endo

89 To study the effect of short N-acetylglucosamine (GlcNAc) oligosaccharides on the phy

90 Dynamic cycling of N-Acetylglucosamine (GlcNAc) on serine and threonine res

91 wide variety of substrates which contain an N-acetylglucosamine (GlcNAc) residue to act as an 'accep

92 -translationally modified by adding O-linked N-acetylglucosamine (GlcNAc) residue to serine or threon

93 modules recognize polysaccharides containing N-acetylglucosamine (GlcNAc) residues including peptidog

94 e reducing end glucose of CPS and the beta-D-N-acetylglucosamine (GlcNAc) residues of peptidoglycan (

95 Chitin, a homopolymer of beta1,4-linked N-acetylglucosamine (GlcNAc) residues, is a key componen

96 polyrhamnose backbone with an immunodominant N-acetylglucosamine (GlcNAc) side chain, which is the ba

97 and consists of a polyrhamnose polymer, with N-acetylglucosamine (GlcNAc) side chains, which is an es

98 N-acetylglucosamine (GlcNAc) stimulates important signal

99 MX regulates formation of N-acetylglucosamine (GlcNAc) terminated N-glycans that p

100 f core-2 O-glycan branch through addition of N-acetylglucosamine (GlcNAc) to a core-1 O-glycan struct

101 tic Fringe) and MFNG (Manic Fringe) transfer N-acetylglucosamine (GlcNAc) to O-fucose attached to EGF

102 The transfer of N-acetylglucosamine (GlcNAc) to Ser or Thr in cytoplasmi

103 modifies protein function by attaching beta-N-acetylglucosamine (GlcNAc) to serine and threonine res

104 ations of PgaB show a binding preference for N-acetylglucosamine (GlcNAc) to the N-terminal domain an

105 O-linked N-acetylglucosamine (GlcNAc) transferase (OGT) is the on

106 Here, we show that O-linked N-acetylglucosamine (GlcNAc) transferase (OGT), an enzym

107 functional homologue of the Candida albicans N-acetylglucosamine (GlcNAc) transporter NGT1, and repre

108 rce for glycolysis and chitobiose to produce N-acetylglucosamine (GlcNAc), a key component of the bac

109 cribed to contain the sugars rhamnose (Rha), N-acetylglucosamine (GlcNAc), galactose (Gal), xylose (X

110 Various stimuli, including N-acetylglucosamine (GlcNAc), induce the fungal pathogen

111 nthesis of a tetra-antennary glycan that has N-acetylglucosamine (GlcNAc), N-acetyllactosamine (LacNA

112 ementation of culture media with uridine and N-acetylglucosamine (GlcNAc), precursors for the hexosam

113 ranslational modification with O-linked beta-N-acetylglucosamine (GlcNAc), promoted apoptosis through

114 em to form hyphae in response to the inducer N-acetylglucosamine (GlcNAc), suggesting that a basal le

115 n death domain-containing host proteins with N-acetylglucosamine (GlcNAc), thereby blocking extrinsic

116 nary glycan [A3(2,4,2) type] terminated with N-acetylglucosamine (GlcNAc), which is generated by N-ac

117 from the cheaper and commercially available N-acetylglucosamine (GlcNAc).

118 s are mainly composed of virally synthesized N-acetylglucosamine (GlcNAc).

119 r results of many cysteine residues bound to N-acetylglucosamine (GlcNAc).

120 lin, demonstrating that the 6-O-sulfation of N-acetylglucosamine (GlcNAc-6-O-sulfation) is highly con

121 N-glycan precursor [glucose(Glc)](3)(Man)(9)[N-acetylglucosamine(GlcNAc)](2).

122 -1 is functionally modified by O-linked beta-N-acetylglucosamine glycosylation (O-GlcNAcylation).

123 on is the presence of a nonreducing terminal N-acetylglucosamine; however, this residue is normally a

124 osamine transferase (OGT), and O-linked beta-N-acetylglucosamine hydrolase in control and IPAH cells

125 erial cells as demonstrated by inhibition of N-acetylglucosamine incorporation into polymeric cell wa

126 In H. jecorina-produced HjCel3A, a single N-acetylglucosamine is present at both sites, whereas in

127 Also, N-acetylglucosamine is selectively oxidized at C3.

128 Chitin, a biopolymer of N-acetylglucosamine, is abundant in invertebrates and fu

129 sion of chitin, a beta-1,4 linked polymer of N-acetylglucosamine, is of major interest in areas varyi

130 Specificity studies with human N-acetylglucosamine kinase and hexokinase IV indicated a

131 izes residues that are already modified with N-acetylglucosamine, likely by converting into a relaxed

132 O-linked N-acetylglucosamine linkage (O-GlcNAcylation) to serine

133 phosphate-N-acetylmuramic acid(pentapeptide)-N-acetylglucosamine (lipid II), which is readily accessi

134 s for a unique phosphotransferase system and N-acetylglucosamine metabolism suggests an important eco

135 roduces UDP-N-acetylglucosamine for O-linked N-acetylglucosamine modification (O-GlcNAcylation) of pr

136 ated by cAMP (EPAC), involving also O-linked N-acetylglucosamine modification downstream of the hexos

137 MCs resulted in reduced global O-linked beta-N-acetylglucosamine modification levels and abrogated PA

138 We measured the levels of O-linked beta-N-acetylglucosamine modification, O-linked beta-N-acetyl

139 biosynthetic pathway, which allows O-linked N-acetylglucosamine modifications of proteins.

140 the addition of the phosphothreonine to the N-acetylglucosamine moiety and CD0243 transfers the meth

141 trongest interactions are established by the N-acetylglucosamine moiety in the central region of the

142 composed of N-acetylmuramic acid-(beta-1,4)-N-acetylglucosamine (MurNAc-GlcNAc) disaccharides associ

143 ing amino sugars [i.e., N-acetylmuramic acid-N-acetylglucosamine (MurNAc-GlcNAc)] from attached pepti

144 he enzymes phosphomannomutase (PMM), phospho-N-acetylglucosamine mutase (PAGM) and phosphoglucomutase

145 ins was reduced by selective inactivation of N-acetylglucosamine N-deacetylase-N-sulfotransferase (Nd

146 g uniform responses (d-lactose, d-galactose, N-acetylglucosamine, N-acetylneuraminic acid), 'all-or-n

147 motility, decreased chemotactic responses to N-acetylglucosamine (NAG) and attenuated ability to diss

148 ing azides and alkynes were installed on tri-N-acetylglucosamine (NAG)3, a PG mimic, as well as PG is

149 tional addition and removal of O-linked beta-N-acetylglucosamine (O-GlcNAc) also occurs on serine res

150 e signaling pathway, terminating in O-linked-N-acetylglucosamine (O-GlcNAc) cycling, is a key sensor

151 O-linked beta-N-acetylglucosamine (O-GlcNAc) glycosylation is a regula

152 ation controlled by the enzyme O-linked-beta-N-acetylglucosamine (O-GlcNAc) glycosyltransferase as co

153 lear and cytosolic proteins by O-linked beta-N-acetylglucosamine (O-GlcNAc) has been shown to play an

154 O-Linked beta-N-acetylglucosamine (O-GlcNAc) is a carbohydrate post-tr

155 O-linked N-acetylglucosamine (O-GlcNAc) is a post-translational m

156 O-Linked beta-N-acetylglucosamine (O-GlcNAc) is a post-translational m

157 slational protein modification O-linked beta-N-acetylglucosamine (O-GlcNAc) is a proposed nutrient se

158 O-linked N-acetylglucosamine (O-GlcNAc) is a reversible posttrans

159 O-linked beta-N-acetylglucosamine (O-GlcNAc) is a reversible posttrans

160 Glycosylation with O-linked beta-N-acetylglucosamine (O-GlcNAc) is one of the protein gly

161 Cellular O-linked N-acetylglucosamine (O-GlcNAc) levels are modulated by t

162 O-Linked beta-N-acetylglucosamine (O-GlcNAc) modification found on the

163 We studied O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of contracti

164 O-linked beta-N-acetylglucosamine (O-GlcNAc) modification of cytoplasm

165 refute the hypothesis of extensive O-linked N-acetylglucosamine (O-GlcNAc) modification of endogenou

166 Although the O-linked N-acetylglucosamine (O-GlcNAc) modification of the RNA p

167 O-linked N-acetylglucosamine (O-GlcNAc) modifications regulate th

168 show that Oct1 is modified by O-linked beta-N-acetylglucosamine (O-GlcNAc) moieties.

169 is study, we show that TAB1 is modified with N-acetylglucosamine (O-GlcNAc) on a single site, Ser395.

170 posttranslational addition of O-linked beta-N-acetylglucosamine (O-GlcNAc) on intracellular proteins

171 Dynamic cycling of O-linked beta-N-acetylglucosamine (O-GlcNAc) on nucleocytoplasmic prot

172 Evidence suggests that the O-linked N-acetylglucosamine (O-GlcNAc) posttranslational modific

173 this study, we demonstrate that the O-linked N-acetylglucosamine (O-GlcNAc) processing enzymes, O-Glc

174 ost-translational modification O-linked beta-N-acetylglucosamine (O-GlcNAc) regulates thousands of nu

175 cess of interest is the addition of O-linked N-acetylglucosamine (O-GlcNAc) residues onto nuclear and

176 is the covalent addition of an O-linked beta-N-acetylglucosamine (O-GlcNAc) sugar moiety to hydroxyl

177 ined, in part, by the attachment of O-linked N-acetylglucosamine (O-GlcNAc) to proteins (O-GlcNAcylat

178 are reversibly glycosylated by O-linked beta-N-acetylglucosamine (O-GlcNAc) to regulate their functio

179 slational addition of a single O-linked beta-N-acetylglucosamine (O-GlcNAc) to serine or threonine re

180 post-translational addition of O-linked beta-N-acetylglucosamine (O-GlcNAc) to various nuclear and cy

181 O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) is an e

182 Here we demonstrate that O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) is requ

183 The nutrient sensor O-linked-beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) modifie

184 N-Acetylglucosamine (O-GlcNAc) transferase (OGT) regulat

185 how that DELLAs are modified by the O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT) SECRET

186 amine biosynthesis pathway and O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT) to pote

187 t TET2 and TET3 associate with O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT), an enz

188 We identifed O-linked-N-acetylglucosamine (O-GlcNAc) transferase (OGT), an X-l

189 AMPK directly phosphorylates O-linked beta-N-acetylglucosamine (O-GlcNAc) transferase (OGT).

190 ent-responsive glycosyltransferase, O-linked N-acetylglucosamine (O-GlcNAc) transferase (OGT).

191 We demonstrate that O-linked N-acetylglucosamine (O-GlcNAc), a post-translational mod

192 One such signal, O-linked beta-N-acetylglucosamine (O-GlcNAc), is an essential post-tra

193 ugh a modification in the amount of O-linked N-acetylglucosamine (O-GlcNAc)-modified proteins and in

194 covalent modification of CaMKII by O-linked N-acetylglucosamine (O-GlcNAc).

195 osolic and nuclear proteins by O-linked beta-N-acetylglucosamine (O-GlcNAc).

196 proteins by monosaccharides of O-linked beta-N-acetylglucosamine (O-GlcNAc).

197 nuclear and cytoplasmic protein by O-linked N-acetylglucosamine (O-GlcNAc).

198 ion of serine/threonine residues by O-linked N-acetylglucosamine (O-GlcNAc).

199 al modification of proteins by O-linked beta-N-acetylglucosamine (O-GlcNAcylation) is a key metabolic

200 lity and protein glycosylation with O-linked N-acetylglucosamine (O-GlcNAcylation) on HA and chondroi

201 al modification of proteins with beta-linked N-acetylglucosamine (O-GlcNAcylation) via overexpression

202 creased modification of proteins by O-linked N-acetylglucosamine (O-GlcNAcylation).

203 ride beta-N-acetylmuramic acid, (1-->4)-beta-N-acetylglucosamine of staphylococcal peptidoglycan.

204 etween the aromatic side chain and the first N-acetylglucosamine of the glycan.

205 ylation, sialylation, and level of bisecting N-acetylglucosamine of the IgG glycans.

206 tify the pattern of O-glycosylation (21 mono-N-acetylglucosamines) of its AST domain.

207 lammatory and stress responses, and O-linked N-acetylglucosamine (OGN) transferase (OGT), an enzyme t

208 the reaction of free MurA and substrate UDP-N-acetylglucosamine or isomer UDP-N-acetylgalactosamine.

209 o hydrolyze the beta-linkages joining either N-acetylglucosamine or N-acetylgalactosamine to a wide v

210 O-Linked beta-N-acetylglucosamine, or O-GlcNAc, is a dynamic post-tran

211 substrates (a mix of substrates, glutamine, N-acetylglucosamine, or pyruvate) revealed contrasting c

212 eous route of infection due to poly-beta-1,6-N-acetylglucosamine overproduction.

213 nally predicted putative miR-185 targets UDP-N-acetylglucosamine-peptide N-acetylglucosaminyltransfer

214 tact O antigen, a capsule mutant, and a poly-N-acetylglucosamine (PGA) mutant.

215 olysaccharide intercellular adhesin, or poly N-acetylglucosamine (PIA/PNAG).

216 Poly-N-acetylglucosamine (PNAG) is a major component of the S

217 e conserved cell surface polysaccharide poly-N-acetylglucosamine (PNAG) were effective at mediating r

218 , encoding the biosynthesis of poly-beta-1,6-N-acetylglucosamine (PNAG), a major biofilm matrix compo

219 ne isolate and found to be negative for poly-N-acetylglucosamine (PNAG)-like material by immunoblot a

220 roadly expressed microbial carbohydrate poly-N-acetylglucosamine (PNAG).

221 Two intracellular enzymes, UDP-N-acetylglucosamine-polypeptide beta-N-acetylglucosaminy

222 rase O-GlcNAc transferase (uridine diphospho-N-acetylglucosamine:polypeptide beta-N-acetylaminyltrans

223 UDP-N-acetylglucosamine pyrophosphorylase (UAP) is the final

224 mmy codes for the single UDP-N-acetylglucosamine pyrophosphorylase in Drosophila, and

225 2-FGFR1c2 can tolerate an HS chain having an N-acetylglucosamine residue at its non-reducing end.

226 hed to the proximal (reducing-terminal) core N-acetylglucosamine residue of N-glycans by beta1,4-link

227 calpha1,3 moiety attached to the distal core N-acetylglucosamine residue was detected.

228 matode glycan cores, specifically the distal N-acetylglucosamine residue; this result is in accordanc

229 N-glycan structure of seven mannosyl and two N-acetylglucosamine residues (Man7GlcNAc2) on misfolded

230 a linear tetrasaccharide that contained two N-acetylglucosamine residues and a free OH group gave tw

231 f Cnm and strongly suggested the presence of N-acetylglucosamine residues attached to Cnm.

232 olves the attachment of single beta-O-linked N-acetylglucosamine residues to serine and threonine res

233 bonds between N-acetylmuramic acid (NAM) and N-acetylglucosamine residues with concomitant formation

234 3-O-fucosyl or 6-O-sulfo substituents in the N-acetylglucosamine residues.

235 illus niger in deglycosylated and Asn-linked N-acetylglucosamine-stub forms reveal a 10(2/3)-turn par

236 r magnetic resonance and shown to contain an N-acetylglucosamine substituted with a phosphorylated N-

237 ble for the selective phosphorylation of the N-acetylglucosamine sugar in a teicoplanin A2-2 derivati

238 s dynamically modified with an O-linked beta-N-acetylglucosamine sugar in response to hypoxia.

239 The enzymatic addition of a single beta-D-N-acetylglucosamine sugar molecule on serine and/or thre

240 ation consisting of the addition of a single N-acetylglucosamine sugar to serine and threonine residu

241 evated post-translational addition of beta-D-N-acetylglucosamine sugars to nuclear and cytoplasmic pr

242 Evidently, hexosamine pathway activation or N-acetylglucosamine supplementation induces distinct pro

243 h control of HmsHFRS-dependent poly-beta-1,6-N-acetylglucosamine synthesis.

244 The dynamic cycling of N-acetylglucosamine (termed O-GlcNAcylation) on serine o

245 esidue is in closer proximity (7.6 A) to the N-acetylglucosamine than the two other sugar rings prese

246 Chitin is a polymer of N-acetylglucosamine that is abundant and widely found in

247 lammasome activation is caused by release of N-acetylglucosamine that is detected in the cytosol by t

248 lytic itineraries for other sugars; for beta-N-acetylglucosamine, the key N-acetyl arm confounds the

249 These results demonstrate that glucose and N-acetylglucosamine, the most readily available chiral b

250 seK3, which is essential for the transfer of N-acetylglucosamine to arginine residues (arginine-GlcNA

251 Sf-GNT-I transferred N-acetylglucosamine to Man(5)GlcNAc(2), Man(3)GlcNAc(2),

252 Sf-GNT-II only transferred N-acetylglucosamine to Man(alpha1-6)[GlcNAc(beta1-2)Man(

253 acetylmannosamine kinase that transforms UDP-N-acetylglucosamine to N-acetylmannosamine (ManNAc) foll

254 Fringe enzymes add N-acetylglucosamine to O-fucose and modify Notch signali

255 -BP1 is also subject to covalent addition of N-acetylglucosamine to Ser or Thr residues (O-GlcNAcylat

256 ne such modification is addition of O-linked N-acetylglucosamine to serine or threonine residues, kno

257 modification involving the O-linkage of beta-N-acetylglucosamine to serine/threonine residues of memb

258 Addition of the N-glycan precursor N-acetylglucosamine to the growth medium slows aging in

259 functions as a ligase that adds the terminal N-acetylglucosamine to the lipooligosaccharide core of Y

260 The essential mammalian enzyme O-linked beta-N-acetylglucosamine transferase (O-GlcNAc transferase, h

261 s involved in cell metabolism: O-linked beta-N-acetylglucosamine transferase (OGT) and isocitrate deh

262 O-Linked N-acetylglucosamine transferase (OGT) catalyzes O-GlcNAc

263 O-Linked beta-N-acetylglucosamine transferase (OGT) is an essential hu

264 O-linked N-acetylglucosamine transferase (OGT) is found in all me

265 tumors from colon tumor cells with O-linked N-acetylglucosamine transferase (OGT) knockdown grew sig

266 cetylglucosamine modification, O-linked beta-N-acetylglucosamine transferase (OGT), and O-linked beta

267 ts with host cell factor-1 (HCF-1), O-linked N-acetylglucosamine transferase (OGT), and the polycomb

268 dues in proteins by the enzyme O-linked beta-N-acetylglucosamine transferase (OGT), whereas the enzym

269 ces an essential substrate for O-linked beta-N-acetylglucosamine transferase (OGT), which glycosylate

270 is a putative serine and threonine O-linked N-acetylglucosamine transferase (OGT).

271 C also interacts with the O-GlcNAc (O-linked N-acetylglucosamine) transferase SPINDLY required for pr

272 GOLPH3 supports incorporation of both core 2 N-acetylglucosamine-transferase 1 and alpha-2,6-sialyltr

273 to control the Golgi localization of core 2 N-acetylglucosamine-transferase 1.

274 that EXTL2 exhibited much stronger in vitro N-acetylglucosamine-transferase activity related to elon

275 SLC35A3 is considered the main UDP-N-acetylglucosamine transporter (NGT) in mammals.

276 galactose transporter (UGT; SLC35A2) and UDP-N-acetylglucosamine transporter (NGT; SLC35A3) form hete

277 65000) as an ER-localized facilitator of UDP-N-acetylglucosamine (UDP-GlcNAc) and UDP-N-acetylgalacto

278 re we show that TpeL preferably utilizes UDP-N-acetylglucosamine (UDP-GlcNAc) as a sugar donor.

279 exosamine biosynthetic pathway, increase UDP-N-acetylglucosamine (UDP-GlcNAc) availability, and lead

280 d thatlymphostatin binds uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc) but not UDP-glucose (UD

281 pathway (HBP) generates uridine diphosphate N-acetylglucosamine (UDP-GlcNAc) for glycan synthesis an

282 The sugar nucleotide UDP-N-acetylglucosamine (UDP-GlcNAc) is an essential metabol

283 Uridine 5'-diphosphate-N-acetylglucosamine (UDP-GlcNAc) is the donor sugar subs

284 The HBP end product UDP-N-acetylglucosamine (UDP-GlcNAc) is used in enzymatic po

285 rikingly, addition of the HBP metabolite UDP-N-acetylglucosamine (UDP-GlcNAc) to CRPC-like cells sign

286 the transfer of N-acetylglucosamine from UDP-N-acetylglucosamine (UDP-GlcNAc) to serines and threonin

287 intracellular levels of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc), a key precursor of Lac

288 tamine are precursors of uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), a substrate for cellul

289 -biosynthesis precursor, uridine diphosphate N-acetylglucosamine (UDP-GlcNAc), was monitored by recor

290 In complex with the cosubstrate UDP-N-acetylglucosamine (UDP-GlcNAc),O-linked-GlcNAc transfe

291 thway (HBP), to increase uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

292 ules UDP-glucuronic acid (UDP-GlcUA) and UDP-N-acetylglucosamine (UDP-GlcNAc).

293 talyzes the formation of uridine diphosphate-N-acetylglucosamine (UDP-GlcNAc).

294 DP-glucuronic acid, and UGT3 enzymes use UDP-N-acetylglucosamine, UDP-glucose, and UDP-xylose to conj

295 el, ChiA variants with weaker binding of the N-acetylglucosamine unit either in substrate-binding sit

296 t core alpha1,3-fucosylation of the proximal N-acetylglucosamine was abolished, the degree of galacto

297 nities for uncharged substrates (glucose and N-acetylglucosamine) were also enhanced, despite competi

298 step in the synthesis of uridine diphosphate N-acetylglucosamine, which is required for the biosynthe

299 version of UDP-N-acetylgalactosamine and UDP-N-acetylglucosamine while the bacterial enzyme cannot.

300 y beta4 addition of N-acetylgalactosamine to N-acetylglucosamine with formation of the N,N-diacetylla