ライフサイエンスコーパス: N-acetyltransferase

1 ated from serotonin by AANAT (arylalkylamine N-acetyltransferase).

2 minoazobenzene-4'-sulfonic acid by arylamine N-acetyltransferase.

3 d by the need for large amounts of arylamine N-acetyltransferase.

4 ounds were tested against purified serotonin N-acetyltransferase.

5 e 1 and Serratia marcescens aminoglycoside 3-N-acetyltransferase.

6 ransferase activity active site on serotonin N-acetyltransferase.

7 tly attached leader peptides and a GNAT-type N-acetyltransferase.

8 polyamine bound in an allosteric site of an N-acetyltransferase.

9 ficant impact on the activities of arylamine N-acetyltransferase.

10 AT as a member of the GCN5-related family of N-acetyltransferases.

11 isubstrate analogs with other aminoglycoside N-acetyltransferases.

12 adopt a fold similar to that of GCN5-related N-acetyltransferases.

13 he defining member of a large superfamily of N-acetyltransferases.

14 n all domains of life that is carried out by N-acetyltransferases.

15 alogous to motifs A, B and D, found in other N-acetyltransferases.

16 s homologous to several microbial antibiotic N-acetyltransferases.

17 otein shows similarity to a diverse group of N-acetyltransferases.

18 nprecedented C-terminal domain homologous to N-acetyltransferases.

19 We found that the enzyme arylalkylamine N-acetyltransferase 1 (AANAT1) is expressed by Drosophil

20 y catalyzed by a vesicular pool of a-tubulin N-acetyltransferase 1 (Atat1), promotes the recruitment

21 pression of HBP enzyme glucosamine-phosphate N-acetyltransferase 1 (GNPNAT1) is found to be significa

22 Two different isoforms of this protein, N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (

23 Arylamine N-acetyltransferase 1 (NAT1) is a drug-metabolizing enzy

24 Arylamine N-acetyltransferase 1 (NAT1) is a phase II xenobiotic-me

25 Human arylamine N-acetyltransferase 1 (NAT1), a polymorphic xenobiotic m

26 ng single-nucleotide polymorphisms (SNPs) in N-acetyltransferase 1 (NAT1), NAT2, and epoxide hydrolas

27 Human arylamine N-acetyltransferase 1 (NAT1), present in all tissues, is

28 The latter was catalyzed by N-acetyltransferase 1 alone as normal human epidermal ke

29 s as selective inhibitors of human arylamine N-acetyltransferase 1 and mouse arylamine N-acetyltransf

30 There is growing evidence that arylamine N-acetyltransferase 1 has an important cellular role in

31 ferase M1, glutathione-S-transferase T1, and N-acetyltransferases 1 and 2.

32 microtubule acetylating agent, alpha-tubulin-N-acetyltransferase-1 (alpha-TAT1), remain obscure.

33 Currently there is much interest in the N-acetyltransferase-1 (NAT1) genetic polymorphism and it

34 abilities of brain metastasis and identified N-acetyltransferase 10 (NAT10) as a driver of brain meta

35 N-acetyltransferase 10 (NAT10) is an N(4)-acetylcytidine

36 ine (ac(4)C) is deposited on diverse RNAs by N-acetyltransferase 10 (NAT10), a protein with high biol

37 Here, we show that ac4C and N-acetyltransferase 10 (NAT10), the enzyme that adds ac4

38 A notable example is N-acetyltransferase 10 (NAT10), which is responsible for

39 melatonin due to mutation of arylalkylamine N-acetyltransferase 2 (aanat2) to show that melatonin is

40 ne 6 (TMPRSS6), transferrin receptor (TFR2), N-acetyltransferase 2 (arylamine N-acetyltransferase) (N

41 The presence of a nonsynonymous variant of N-acetyltransferase 2 (NAT2) [rs1208 (803A>G, K268R)] wa

42 For isoniazid, mutations in the N-acetyltransferase 2 (NAT2) gene explain >88% of pharma

43 cleotide polymorphism in the human arylamine N-acetyltransferase 2 (Nat2) gene has recently been iden

44 A role for the N-acetyltransferase 2 (NAT2) genetic polymorphism in can

45 N-acetyltransferase 2 (NAT2) is the only known locus inf

46 Mutations in N-acetyltransferase 2 (NAT2), a highly polymorphic enzym

47 is protein, N-acetyltransferase 1 (NAT1) and N-acetyltransferase 2 (NAT2), are expressed in human hep

48 and 259 control subjects were genotyped for N-acetyltransferase 2 (NAT2), which codes for a polymorp

49 Conclusions: Dosing of isoniazid based on N-acetyltransferase 2 acetylator status may help patient

50 hA-mutated isolates in slow and intermediate N-acetyltransferase 2 acetylators, respectively.

51 ion between the slow acetylator genotype for N-acetyltransferase 2 and familial PD.

52 ne N-acetyltransferase 1 and mouse arylamine N-acetyltransferase 2 are described.

53 The slow acetylator frequency for N-acetyltransferase 2 for sporadic PD was between that f

54 The N-acetyltransferase 2 gene (NAT2) product is an enzyme i

55 We found that N-acetyltransferase 2 gene (NAT2) slow acetylator status

56 We also investigated N-acetyltransferase 2 in 100 blood samples from patients

57 Phenotypically slow acetylators (N-acetyltransferase 2 index <0.37) had an odds ratio of

58 ulosis (drug sensitive and inhA mutated) and N-acetyltransferase 2 status.

59 The slow acetylator genotype for N-acetyltransferase 2 was more common in the familial PD

60 phenotyped for cytochrome P4501A2 (CYP1A2), N-acetyltransferase 2, and sulfotransferase 1A1 enzyme a

61 ome P-4501A2 (CYP1A2), xanthine oxidase, and N-acetyltransferase 2--by measuring levels of caffeine m

62 ermal keratinocytes did not express mRNA for N-acetyltransferase 2.

63 ase, glutathione transferases M1 and T1, and N-acetyltransferase 2.

64 haplotyping of 11 SNPs within exon 2 of the N-acetyltransferase-2 (NAT2) gene, which expresses an im

65 N-acetyltransferase-2 (NAT2) is an important enzyme that

66 SNPs in the NAT2 (N-acetyltransferase-2) gene explain the majority of inte

67 NAT8L (N-acetyltransferase 8-like) catalyzes the formation of N

68 by constitutive genetic disruption of Nat8l (N-acetyltransferase-8 like) permits normal CNS myelinati

69 ch encodes the neuronal NAA-synthetic enzyme N-acetyltransferase-8-like.

70 lly by methionine aminopeptidase (MetAP) and N-acetyltransferase A (NatA), respectively(1).

71 Serotonin N-acetyltransferase, a member of the GNAT acetyltransfer

72 0- to 100-fold increases in pineal serotonin N-acetyltransferase (AA-NAT) activity.

73 old rhythm in the activity of arylalkylamine N-acetyltransferase (AA-NAT; EC 2.3.1.87) controls the r

74 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase [AA-NAT]).

75 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT, HGMW-approved symbol AANAT;

76 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AA-NAT; EC 2.3.1.87), the penultima

77 The aminoglycoside 3-N-acetyltransferase AAC(3)-IV from Escherichia coli exhi

78 The 2'-N-acetyltransferase [AAC(2')-Ia] in Providencia stuartii

79 ovidencia stuartii contains a chromosomal 2'-N-acetyltransferase [AAC(2')-Ia] involved in the O acety

80 The chromosomally encoded aminoglycoside N-acetyltransferase, AAC(2')-Ic, of Mycobacterium tuberc

81 the chromosomally encoded aminoglycoside 6'-N-acetyltransferase, AAC(6')-Iy, of Salmonella enterica

82 cits in enzymatic activity of arylalkylamine N-acetyltransferase (AANAT) and N-acetylserotonin O-meth

83 Arylalkylamine N-acetyltransferase (AANAT) catalyzes the N-acetylation

84 Arylalkylamine N-acetyltransferase (aaNAT) catalyzes the transacetylati

85 Serotonin N-acetyltransferase (AANAT) controls the daily rhythm in

86 hormone melatonin, is catalyzed by serotonin N-acetyltransferase (AANAT) in a reaction requiring acet

87 Arylalkylamine N-acetyltransferase (AANAT) is the penultimate and key r

88 neurons of melatonin-deficient aralkylamine N-acetyltransferase (AANAT) knockout mice.

89 inding sites in the 3"-UTR of arylalkylamine N-acetyltransferase (Aanat) mRNA, the penultimate enzyme

90 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase (AANAT)) is a critical enzyme in the

91 s for tryptophan hydroxylase, arylalkylamine N-acetyltransferase (AANAT), and hydroxyindole-O-methylt

92 regulated by the activity of arylalkylamine N-acetyltransferase (AANAT), the penultimate enzyme in t

93 otonin in the pineal gland by arylalkylamine N-acetyltransferase (AANAT), the penultimate enzyme in t

94 synthesized from serotonin by arylalkylamine N-acetyltransferase (AANAT), which is predominantly expr

95 melatonin-synthesizing enzyme arylalkylamine N-acetyltransferase (AANAT).

96 yme in melatonin synthesis is arylalkylamine N-acetyltransferase (AANAT).

97 erotonin N-acetyltransferase [arylalkylamine N-acetyltransferase (AANAT)] is a key circadian rhythm e

98 Arylalkylamine N-acetyltransferase (AANAT, serotonin N-acetyltransferas

99 nzyme in melatonin synthesis, arylalkylamine N-acetyltransferase (AANAT; serotonin N-acetyltransferas

100 After overexpression of arylalkylamine N-acetyltransferase (AANAT; the enzyme regulating melato

101 aluated the (1) expression of arylalkylamine N-acetyltransferase (AANAT; the rate-limiting enzyme for

102 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) in the pineal gland control

103 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) is a member of the GCN5 N-ac

104 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT) mRNA in the chicken pineal g

105 rylalkylamine N-acetyltransferase (serotonin N-acetyltransferase, AANAT, EC ) is the penultimate enzy

106 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT, EC 2.3.1.87) is the first en

107 erotonin N-acetyltransferase (arylalkylamine N-acetyltransferase, AANAT, EC 2.3.1.87) is the penultim

108 tyltransferase (also known as arylalkylamine N-acetyltransferase; AANAT) bound to a potent bisubstrat

109 mRNA level of arylalkylamine-N-acetyltransferase (AANAT2), a key enzyme of melatonin

110 This binding activates N-acetyltransferase activity in the C-terminal GCN5-rela

111 While in metazoa, NAA50 has N-acetyltransferase activity, yeast NAA50 is catalytical

112 Agmatine N-acetyltransferase (AgmNAT) catalyzes the formation of

113 The structure of serotonin N-acetyltransferase (also known as arylalkylamine N-acet

114 Serotonin N-acetyltransferase, also called the melatonin rhythm en

115 , to identify inhibitors targeting aspartate N-acetyltransferase (ANAT), a promising target for the t

116 lex structure with those of 14-3-3:serotonin N-acetyltransferase and 14-3-3:heat shock protein beta-6

117 romycin or OPP in cells expressing puromycin N-acetyltransferase and detection of translation in othe

118 protein, which turns on the transcription of N-acetyltransferase and inducible cAMP early repressor,

119 ction of recombinant chicken liver arylamine N-acetyltransferase and optimization of its use in minia

120 to this previously uncharacterized family of N-acetyltransferases and also provide a molecular framew

121 a member of the superfamily of GCN5-related N-acetyltransferases and catalyzes the covalent attachme

122 beta1-AR-driven increase in cAMP, serotonin N-acetyltransferase, and melatonin production.

123 ynthase, homospermidine synthase, spermidine N-acetyltransferase, and N-acetylspermidine amidohydrola

124 andidate tumor suppressor, Charlatan, and an N-acetyltransferase, ARD1.

125 gulatory systems that control arylalkylamine N-acetyltransferase are a circadian clock and environmen

126 Bisubstrate analogs for the aminoglycoside N-acetyltransferases are nanomolar inhibitors of Enteroc

127 Here, we show that the N-acetyltransferase arrest-defect 1 protein (ARD1) funct

128 Serotonin N-acetyltransferase (arylalkylamine N-ace-tyltransferase

129 ated by changes in the activity of serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase

130 Serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase

131 Serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase,

132 Large changes in the activity of serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase,

133 The abundance of serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase,

134 Serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase,

135 Serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase,

136 rcadian changes in the activity of serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase,

137 Serotonin N-acetyltransferase (arylalkylamine N-acetyltransferase,

138 Serotonin N-acetyltransferase [arylalkylamine N-acetyltransferase

139 ne for the NAA biosynthetic enzyme aspartate N-acetyltransferase (Asp-NAT).

140 thetase (BACS) and bile acid-CoA: amino acid N-acetyltransferase (BAT) are induced by FXR in rat live

141 in its biosynthesis is catalyzed by PerB, an N-acetyltransferase belonging to the left-handed beta-he

142 eins belonging to the bacterial GCN5-related N-acetyltransferase (bGNAT) superfamily acetylate the ep

143 (GNAT), Serratia marcescens aminoglycoside 3-N-acetyltransferase, bound to coenzyme A (CoA) has been

144 in is similar to those of other GCN5-related N-acetyltransferases but the carboxy-terminal domain is

145 y used mammalian selection marker, puromycin N-acetyltransferase, can be repurposed for cell-specific

146 mical analyses indicate that PaiA is a novel N-acetyltransferase capable of acetylating both spermidi

147 hibition is suggested to involve a serotonin N-acetyltransferase-catalyzed alkylation reaction betwee

148 eficiency of acetyl-CoA: alpha-glucosaminide N-acetyltransferase causes lysosomal accumulation of hep

149 functions as the noncatalytic subunit of the N-acetyltransferase complex B (NatB) to maintain the num

150 Arylalkylamine N-acetyltransferase controls daily changes in melatonin

151 acterized circadian rhythm enzyme, serotonin N-acetyltransferase, displayed significant FRET, indicat

152 oxal phosphate binding domain is fused to an N-acetyltransferase domain related to the general contro

153 rase activity in the C-terminal GCN5-related N-acetyltransferase domain, which is required for GlcNAc

154 lamine N-acetyltransferase (AANAT, serotonin N-acetyltransferase, EC ) plays a unique transduction ro

155 lamine N-acetyltransferase (AANAT; serotonin N-acetyltransferase, EC ).

156 Cat and is activated by the WhiB7-dependent N-acetyltransferase Eis2 in a prodrug fashion to generat

157 d the N-terminal domain of an aminoglycoside N-acetyltransferase, encoded by a plasmid-borne antibiot

158 Spermidine N-acetyltransferase, encoded by the gene speG, catalyzes

159 ed an additional gene copy of apolipoprotein N-acetyltransferase enzyme (Lnt)-rich Escherichia coli s

160 ion is introduced by bacterial Gcn-5-related N-acetyltransferase enzymes and can be removed by bacter

161 ns that show no sequence conservation within N-acetyltransferase enzymes, is implicated by cross-spec

162 his is the first structure of a Gcn5-related N-acetyltransferase family member with demonstrated acti

163 50 and NHERF1) and NAT9, a new member of the N-acetyltransferase family.

164 KAT2A) is a member of the GNAT (Gcn5-related N-acetyltransferase) family of HATs.

165 ed that the two enzymes share a Gcn5-related N-acetyltransferase fold but differ in their respective

166 pite the established function as a bona fide N-acetyltransferase, FrbF shows no sequence similarity t

167 GAT is an N-acetyltransferase from Bacillus licheniformis that was

168 We have solved the structure of arylamine N-acetyltransferase from M. smegmatis at a resolution of

169 ins at least one tumour suppressor gene, the N-acetyltransferase functions of Fus-2 may be relevant t

170 Consistent with other N-acetyltransferases, Fus-2 localizes to the cytoplasm,

171 and discovered enzymes exhibiting glyphosate N-acetyltransferase (GAT) activity.

172 expression of 3OST2 in the night pineals on N-acetyltransferase gene expression and melatonin produc

173 laspartate (NAA) is synthesized by aspartate N-acetyltransferase (gene: Nat8l) from acetyl-coenzyme A

174 emical evidence that glucosamine 6-phosphate N-acetyltransferase (Gna1), a key enzyme in this pathway

175 e best characterized are the Gcn5-containing N-acetyltransferase (GNAT) complexes.

176 A central GCN5-related N-acetyltransferase (GNAT) domain bears bifunctional dec

177 MEC-17 core adopts a canonical Gcn5-related N-acetyltransferase (GNAT) fold that is decorated with e

178 a bilobed protein containing a GCN5-related N-acetyltransferase (GNAT) fold, and this crystalline be

179 ltransferase, AANAT) is a member of the GCN5 N-acetyltransferase (GNAT) superfamily and catalyzes the

180 The Gcn5-related N-acetyltransferase (GNAT) superfamily is a large group

181 eron, a divergent member of the Gcn5-related N-acetyltransferase (GNAT) superfamily of enzymes whose

182 Hpa2 is a member of the Gcn5-related N-acetyltransferase (GNAT) superfamily, a family of enzy

183 AcuA protein is a member of the Gcn5-related N-acetyltransferase (GNAT) superfamily, the AcuC protein

184 ce similarity to any member of the GCN5-like N-acetyltransferase (GNAT) superfamily.

185 X-ray structure of a canonical GCN5-related N-acetyltransferase (GNAT), Serratia marcescens aminogly

186 named here as HqbA), a putative Gcn5-related N-acetyltransferase (GNAT), was previously identified as

187 gradation, and YhbS, a putative GCN5-related N-acetyltransferase (GNAT).

188 ylation reactions belong to the Gcn5-related N-acetyltransferase (GNAT; PF00583) family, named after

189 eled by a downregulation of the GCN5-related N-acetyltransferases (GNAT) p300/CBP-associated factor a

190 GCN5-type N-acetyltransferases (GNATs) are enzymes that catalyse t

191 ral control non-repressible 5 (GCN5)-related N-acetyltransferases (GNATs) catalyse the acetylation of

192 Gcn5-related N-acetyltransferases (GNATs), named after their founding

193 me is a member of the GCN5-related family of N-acetyltransferases (GNATs), which share four conserved

194 with the coenzyme-bound forms of the related N-acetyltransferases, HAT1 (yeast histone acetyltransfer

195 Histone N-acetyltransferases (HATs) are a group of enzymes which

196 -unrelated human heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT) support a similar transmemb

197 Heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT), a resident of the lysosoma

198 paran sulfate acetyl-CoA:alpha-glucosaminide N-acetyltransferase (HGSNAT), which are potentially trea

199 membrane enzyme heparan-alpha-glucosaminide N-acetyltransferase (HGSNAT).

200 omoters of pineal-selective enzymes, such as N-acetyltransferase, hydroxyindole-O-methyl transferase,

201 in A in the active site of aminoglycoside 6'-N-acetyltransferase-Ii [AAC-(6')-Ii].

202 The results suggest that leptin activates a N-acetyltransferase in POMC neurons, leading to increase

203 h for genes involved in regulation of the 2'-N-acetyltransferase in Providencia stuartii, a mini-Tn5C

204 Normal induction of spermidine/spermine N-acetyltransferase in Q19 lines regulating back-convers

205 rapidly induced the enzymatic activity of a N-acetyltransferase in the hypothalamus of mice.

206 nd l-valine was afforded by two GCN5-related N-acetyltransferases in a tRNA-dependent manner.

207 mation, and presence of functional polyamine N-acetyltransferases in S. aureus and E. faecalis repres

208 structure among the microbial and eukaryotic N-acetyltransferases in the region corresponding to the

209 A shares recognizable sequence homology with N-acetyltransferases, including those that can acetylate

210 tructurally conserved among a superfamily of N-acetyltransferases, including yeast histone acetyltran

211 Comparison with related N-acetyltransferases indicates a conserved structural fr

212 eficiency of acetyl-CoA: alpha-glucosaminide N-acetyltransferase involved in the lysosomal catabolism

213 Arylalkylamine N-acetyltransferase is also expressed in the retina, whe

214 Serotonin N-acetyltransferase is the enzyme responsible for the di

215 cs mediated by regioselective aminoglycoside N-acetyltransferases is the predominant cause of bacteri

216 -dependent phosphorylation of arylalkylamine N-acetyltransferase, leading to formation of a regulator

217 erved glutamate residue seen in Gcn5-related N-acetyltransferase-like acyltransferases.

218 A different enzyme from arylalkylamine N-acetyltransferase mediated this reaction, as this gene

219 In serotonin N-acetyltransferase, motif A adopts an alpha/beta confor

220 , and glutathione S-transferase (GST) M1 and N-acetyltransferase (NAT) 2 polymorphisms that may influ

221 One such enzyme is homologous to arylamine N-acetyltransferase (NAT) and has been identified in Fus

222 ns of two pineal-specific enzymes: serotonin N-acetyltransferase (NAT) and hydroxyindole-O-methyltran

223 ns, an amino acid kinase (AAK) domain and an N-acetyltransferase (NAT) domain connected through a 10-

224 like fold but lacking kinase activity and an N-acetyltransferase (NAT) domain homologous to other GCN

225 Arylamine N-acetyltransferase (NAT) enzymes are widespread in natu

226 nogenic heterocyclic amines are activated by N-acetyltransferase (NAT) enzymes, encoded by NAT1 and N

227 The activity of pineal serotonin N-acetyltransferase (NAT) exhibits a large circadian rhy

228 The dominant N-acetyltransferase (Nat) in Arabidopsis (Arabidopsis th

229 bolism of benzidine and N-acetylbenzidine by N-acetyltransferase (NAT) NAT1 and NAT2.

230 s feature ultrathin films containing DNA and N-acetyltransferase (NAT) on pyrolytic graphite (PG) ele

231 tivated by mycobacterial and human arylamine N-acetyltransferase (NAT).

232 phate farnesyltransferase (FDFT1), arylamine N-acetyltransferase (NAT-1), lipoprotein lipase (LPL), a

233 Human N-acetyltransferases (NAT; EC 2.3.1.5) catalyze the N-ac

234 Arylamine N:-acetyltransferase (NAT) was first identified as the i

235 droxylation followed by O-acetylation by the N-acetyltransferases NAT1 and NAT2.

236 Arylamine N-acetyltransferases (NAT1 and NAT2) acetylate and detox

237 ion followed by phase II O-esterification by N-acetyltransferase (NAT2) are generally regarded as act

238 The enzymes cytochrome P4501A2 (CYP1A2) and N-acetyltransferase (NAT2) are principally implicated in

239 tor (TFR2), N-acetyltransferase 2 (arylamine N-acetyltransferase) (NAT2), ABO blood group (ABO), and

240 Arylamine N -acetyltransferases (NATs) catalyse the acetylation fr

241 Arylamine N-acetyltransferases (NATs) are a homologous family of e

242 Arylamine N-acetyltransferases (NATs) are cytosolic enzymes that c

243 Arylamine N-acetyltransferases (NATs) catalyze an acetyl group tra

244 Arylamine N-acetyltransferases (NATs) catalyze an acetyl group tra

245 Arylamine N-acetyltransferases (NATs) catalyze the acetylation of

246 ect of apocynin on the activity of arylamine N-acetyltransferases (NATs) in excised liver samples was

247 otein modification mediated enzymatically by N-acetyltransferases (NATs) that impacts bacterial patho

248 Arylamine N-acetyltransferases (NATs), a class of xenobiotic-metab

249 amino moiety of many proteins is modified by N-acetyltransferases (NATs).

250 Arylamine N-acetyltransferases (NATs; E.C 2.3.1.5) N-acetylate ary

251 Although previously characterized as the N-acetyltransferase of S5, our data indicate that RimJ,

252 conserved domain corresponding to a putative N-acetyltransferase or thioltransferase catalytic site.

253 activities of a C4''-transaminase (Pam), a 4-N-acetyltransferase (Pdi), a UDP-hydrolase (Phy), an enz

254 zymatic activity in vitro, this GCN5-related N-acetyltransferase region is critical for the solubilit

255 with a previously unidentified GCN5-related N-acetyltransferase region.

256 l control non-derepressible 5 (GCN5)-related N-acetyltransferase regions.

257 4,6-dehydratase, an aminotransferase, and an N-acetyltransferase, respectively, which would be requir

258 Arylalkylamine N-acetyltransferase (serotonin N-acetyltransferase, AANA

259 lies lacking one such enzyme, arylalkylamine N-acetyltransferase, show increased rest after rest depr

260 The spermidine N-acetyltransferase SpeG is a dodecameric enzyme that ca

261 We show that spermidine/spermine N-acetyltransferase (SSAT) homologues encoded by S. aure

262 SmAAT (Serratia marcescens aminoglycoside 3-N-acetyltransferase), suggests the mode of substrate bin

263 structural similarity to other Gcn5-related N-acetyltransferase superfamily members.

264 ution and found that PaiA is a member of the N-acetyltransferase superfamily of enzymes.

265 ures have a common fold core of GCN5-related N-acetyltransferase superfamily proteins, along with a u

266 amily 9, isoform 3 regulatory factor), NAT9 (N-acetyltransferase superfamily), and RAPTOR (rapamycin

267 icant similarity of Nut1 to the GCN5-related N-acetyltransferase superfamily.

268 side chains by maturases of the GCN5-related N-acetyltransferase superfamily.

269 c structure for a member of the Gcn5-related N-acetyltransferase superfamily.

270 It is a member of the GNAT (GCN-5-related N-acetyltransferase) superfamily of enzymes, which catal

271 T) and is a member of the GNAT (GCN5 related N-acetyltransferases) superfamily.

272 n contrast, diverse phages encode spermidine N-acetyltransferase that can sequester spermidine into i

273 ation is on the enzyme QdtC, a CoA-dependent N-acetyltransferase that catalyzes the last step in the

274 eptors on pinealocytes activate aralkylamine N-acetyltransferase that converts 5-hydroxytryptamine (5

275 One of these, referred to as WlbB, is an N-acetyltransferase that converts UDP-2-acetamido-3-amin

276 lic mobile element (ACME) encoding a Spm/Spd N-acetyltransferase that is necessary and sufficient for

277 regulation patterns of 3OST2 with serotonin N-acetyltransferase, the enzyme controlling the melatoni

278 d pineal-specific transcription of serotonin N-acetyltransferase, the rate-limiting enzyme in melaton

279 g histone acetyltransferases, aminoglycoside N-acetyltransferases, thioesterases, and enzymes involve

280 When applied to N-acetyltransferases, this reveals sequence and structur

281 w that AtaT2 is the first GNAT (Gcn5-related N-acetyltransferase) toxin that specifically targets cha

282 ponses, photic suppression of arylalkylamine-N-acetyltransferase transcript, and acute suppression of

283 cAMP early repressor, the major inhibitor of N-acetyltransferase transcription.

284 a precursor (triA), macrocyclase (triC), and N-acetyltransferase (triT).

285 y, isoniazid acetylator status determined by N-acetyltransferase type 2 genotype was associated with

286 Gram-negatives is usually mediated by the 6'-N-acetyltransferase type Ib [AAC(6')-Ib], which catalyze

287 a enterica aac(6')-Iy-encoded aminoglycoside N-acetyltransferase, we demonstrate that a series of bis

288 ly annotated as an aminoalkylphosphonic acid N-acetyltransferase which is able to acetylate a range o

289 Arylamine N-acetyltransferases which acetylate and inactivate ison

290 rium tuberculosis possess a single arylamine N-acetyltransferase whose gene is predicted to occur wit

291 zymes, such as epoxide hydrolase, glyphosate N-acetyltransferase, xylanase and phosphotriesterase, in