1 e development of new antimalarials targeting
N-myristoyltransferase.
2 if (M)GXXX(S/T/A) in a reaction catalyzed by
N-myristoyltransferase.
3 and NMT-2 comprise two distinct families of
N-myristoyltransferases.
4 s N-myristoylation of AMPKbeta by the type-I
N-myristoyltransferase 1 (NMT1).
5 related with the catalytic efficiency of the
N-myristoyltransferase acting at the N terminus of the T
6 lso increased in nmt1-181 yeast with reduced
N-myristoyltransferase activity.
7 n of both proteins was attempted using human
N-myristoyltransferase and [(3)H]myristoyl-CoA.
8 AtCPK5 was a substrate for plant
N-myristoyltransferase and myristoylation was prevented
9 Our studies validate T. brucei
N-myristoyltransferase as a promising therapeutic target
10 Northern and Western blot analyses plus
N-myristoyltransferase assays showed that Nmt is normall
11 elopment, likely because it is the principal
N-myristoyltransferase in early embryogenesis.
12 hored proteome with selective small-molecule
N-myristoyltransferase inhibitors.
13 MyristoylCoA:protein
N-myristoyltransferase is a member of the superfamily of
14 We demonstrate that
N-myristoyltransferase is an essential and chemically tr
15 Inhibition of this target-T. brucei
N-myristoyltransferase-
leads to rapid killing of trypano
16 The trypanosomatids possess a single
N-myristoyltransferase (
NMT) and multiple palmitoyl acyl
17 MyristoylCoA:protein
N-myristoyltransferase (
Nmt) attaches myristate to the N
18 N-Myristoyltransferase (
NMT) catalyses the attachment of
19 N-Myristoyltransferase (
NMT) catalyzes the cotranslation
20 MyristoylCoA:protein
N-myristoyltransferase (
NMT) covalently attaches the 14-
21 mics combined with potent and specific human
N-myristoyltransferase (
NMT) inhibition.
22 N-Myristoyltransferase (
NMT) is a prospective drug targe
23 d to determine whether myristoyl-CoA:protein
N-myristoyltransferase (
Nmt) is a target for development
24 N-Myristoyltransferase (
NMT) is an attractive antiprotoz
25 N-Myristoyltransferase (
NMT) is an essential eukaryotic
26 N-Myristoyltransferase (
NMT) represents a promising drug
27 N-Myristoyltransferase (
NMT) represents a promising drug
28 cans produces a single myristoyl-CoA:protein
N-myristoyltransferase (
Nmt) that is essential for its v
29 N-Myristoyltransferase (
NMT) transfers myristate to an a
30 Inhibitors of Leishmania
N-myristoyltransferase (
NMT), a potential target for the
31 Design of inhibitors for
N-myristoyltransferase (
NMT), an enzyme responsible for
32 alyzed by myristoyl-coenzyme A (CoA):protein
N-myristoyltransferase (
NMT), an enzyme ubiquitous in eu
33 Protein N-myristoylation is catalysed by
N-myristoyltransferase (
NMT), an essential and druggable
34 oylation is catalyzed by an enzyme activity,
N-myristoyltransferase (
NMT), which transfers myristic a
35 atalyzed by the enzyme myristoyl-CoA:protein
N-myristoyltransferase (
NMT).
36 MyristoylCoA:protein
N-myristoyltransferase (
Nmt, EC 2.3.1.97), a member of t
37 ctivity by blockade of myristoylCoA: protein
N-myristoyltransferase (
NMT; EC 2.1.3.97).
38 N-myristoyltransferases (
NMT) catalyze co- or posttransl
39 d pharmacologic evidence that inhibiting the
N-myristoyltransferase NMT1 suppresses cell-cycle progre
40 myristoylation enzymes, involving one or two
N-myristoyltransferases (
NMT1 and NMT2), among which NMT
41 ccharomyces cerevisiae myristoyl-CoA:protein
N-myristoyltransferase (
Nmt1p) is an essential 455-resid
42 accharomyces cerevisiae myristoylCoA:protein
N-myristoyltransferase (
Nmt1p) is an essential enzyme th
43 MyristoylCoA:protein
N-myristoyltransferase (
Nmt1p) is an essential enzyme wh
44 the essential enzyme, myristoyl-CoA:protein
N-myristoyltransferase (
Nmt1p).
45 This reaction is catalyzed by
N-myristoyltransferases (
NMTs), which transfer myristate
46 lly, coexpression of a K7,9A-Fyn mutant with
N-myristoyltransferase restored myristoylation, membrane
47 n results from retinal enrichment of unusual
N-myristoyltransferase substrates.
48 Trypanosoma brucei
N-myristoyltransferase (
TbNMT) is an attractive therapeu
49 This reaction is catalyzed by a
N-myristoyltransferase that uses myristoyl-coenzyme A as
50 The method uses the eukaryotic enzyme
N-myristoyltransferase to modify the N-terminus of the p
51 One such putative target is the enzyme
N-myristoyltransferase,
which catalyses the attachment o
52 By co-expressing yeast
N-myristoyltransferase with an elastin-like polypeptide