1 e development of new antimalarials targeting
N-myristoyltransferase.
2 if (M)GXXX(S/T/A) in a reaction catalyzed by
N-myristoyltransferase.
3 and NMT-2 comprise two distinct families of
N-myristoyltransferases.
4 s N-myristoylation of AMPKbeta by the type-I
N-myristoyltransferase 1 (NMT1).
5 somal tethering of AMPK due to deficiency of
N-myristoyltransferase 1 (NMT1).
6 e set to further explore the significance of
N-myristoyltransferase-
1 (NMT1) and TIMM17A expression i
7 N-myristoyltransferase-
1 (NMT1) catalyzes protein myrist
8 related with the catalytic efficiency of the
N-myristoyltransferase acting at the N terminus of the T
9 lso increased in nmt1-181 yeast with reduced
N-myristoyltransferase activity.
10 n of both proteins was attempted using human
N-myristoyltransferase and [(3)H]myristoyl-CoA.
11 AtCPK5 was a substrate for plant
N-myristoyltransferase and myristoylation was prevented
12 ium falciparum acetyl-coenzyme A synthetase,
N-myristoyltransferase,
and the cyclic guanosine monopho
13 Our studies validate T. brucei
N-myristoyltransferase as a promising therapeutic target
14 Northern and Western blot analyses plus
N-myristoyltransferase assays showed that Nmt is normall
15 t on N-terminal myristoylation of MA by host
N-myristoyltransferase enzymes (NMTs), which recognize a
16 gulates the N-myristoylation of proteins via
N-myristoyltransferase enzymes (NMTs).
17 enzymes with conserved binding sites, namely
N-myristoyltransferase from two different organisms, was
18 elopment, likely because it is the principal
N-myristoyltransferase in early embryogenesis.
19 pharmacological properties, but we find that
N-myristoyltransferase inhibitors (NMTi) phenocopy COPI
20 hored proteome with selective small-molecule
N-myristoyltransferase inhibitors.
21 MyristoylCoA:protein
N-myristoyltransferase is a member of the superfamily of
22 We demonstrate that
N-myristoyltransferase is an essential and chemically tr
23 Inhibition of this target-T. brucei
N-myristoyltransferase-
leads to rapid killing of trypano
24 The trypanosomatids possess a single
N-myristoyltransferase (
NMT) and multiple palmitoyl acyl
25 MyristoylCoA:protein
N-myristoyltransferase (
Nmt) attaches myristate to the N
26 N-myristoyltransferase (
NMT) attaches the fatty acid myr
27 The promising drug target
N-myristoyltransferase (
NMT) catalyses an essential prot
28 N-Myristoyltransferase (
NMT) catalyses the attachment of
29 N-Myristoyltransferase (
NMT) catalyzes the cotranslation
30 MyristoylCoA:protein
N-myristoyltransferase (
NMT) covalently attaches the 14-
31 Because cancer cells often have increased
N-myristoyltransferase (
NMT) expression, NMTs were propo
32 mics combined with potent and specific human
N-myristoyltransferase (
NMT) inhibition.
33 N-myristoyltransferase (
NMT) is a promising antimalarial
34 N-Myristoyltransferase (
NMT) is a prospective drug targe
35 d to determine whether myristoyl-CoA:protein
N-myristoyltransferase (
Nmt) is a target for development
36 N-Myristoyltransferase (
NMT) is an attractive antiprotoz
37 N-Myristoyltransferase (
NMT) is an essential eukaryotic
38 N-myristoyltransferase (
NMT) is an essential eukaryotic
39 The enzyme
N-myristoyltransferase (
NMT) is an essential protein, wh
40 N-Myristoyltransferase (
NMT) represents a promising drug
41 N-Myristoyltransferase (
NMT) represents a promising drug
42 cans produces a single myristoyl-CoA:protein
N-myristoyltransferase (
Nmt) that is essential for its v
43 N-Myristoyltransferase (
NMT) transfers myristate to an a
44 Inhibitors of Leishmania
N-myristoyltransferase (
NMT), a potential target for the
45 Design of inhibitors for
N-myristoyltransferase (
NMT), an enzyme responsible for
46 N-Myristoyltransferase (
NMT), an enzyme ubiquitous and e
47 alyzed by myristoyl-coenzyme A (CoA):protein
N-myristoyltransferase (
NMT), an enzyme ubiquitous in eu
48 Protein N-myristoylation is catalysed by
N-myristoyltransferase (
NMT), an essential and druggable
49 oylation is catalyzed by an enzyme activity,
N-myristoyltransferase (
NMT), which transfers myristic a
50 atalyzed by the enzyme myristoyl-CoA:protein
N-myristoyltransferase (
NMT).
51 MyristoylCoA:protein
N-myristoyltransferase (
Nmt, EC 2.3.1.97), a member of t
52 ctivity by blockade of myristoylCoA: protein
N-myristoyltransferase (
NMT; EC 2.1.3.97).
53 N-myristoyltransferases (
NMT) catalyze co- or posttransl
54 EGR2 is N-myristoylated by
N-myristoyltransferase NMT1 at 22 degrees C, which is im
55 d pharmacologic evidence that inhibiting the
N-myristoyltransferase NMT1 suppresses cell-cycle progre
56 myristoylation enzymes, involving one or two
N-myristoyltransferases (
NMT1 and NMT2), among which NMT
57 ccharomyces cerevisiae myristoyl-CoA:protein
N-myristoyltransferase (
Nmt1p) is an essential 455-resid
58 accharomyces cerevisiae myristoylCoA:protein
N-myristoyltransferase (
Nmt1p) is an essential enzyme th
59 MyristoylCoA:protein
N-myristoyltransferase (
Nmt1p) is an essential enzyme wh
60 the essential enzyme, myristoyl-CoA:protein
N-myristoyltransferase (
Nmt1p).
61 N-myristoyltransferases (
NMTs) cotranslationally transfe
62 can be catalyzed during protein synthesis by
N-myristoyltransferases (
NMTs), and its dysregulation ha
63 This reaction is catalyzed by
N-myristoyltransferases (
NMTs), which transfer myristate
64 lly, coexpression of a K7,9A-Fyn mutant with
N-myristoyltransferase restored myristoylation, membrane
65 n results from retinal enrichment of unusual
N-myristoyltransferase substrates.
66 Trypanosoma brucei
N-myristoyltransferase (
TbNMT) is an attractive therapeu
67 This reaction is catalyzed by a
N-myristoyltransferase that uses myristoyl-coenzyme A as
68 The method uses the eukaryotic enzyme
N-myristoyltransferase to modify the N-terminus of the p
69 One such putative target is the enzyme
N-myristoyltransferase,
which catalyses the attachment o
70 clinical stage pharmacological inhibitors of
N-myristoyltransferases,
which reduce tumor growth in xe
71 By co-expressing yeast
N-myristoyltransferase with an elastin-like polypeptide