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1 ontains an additional alpha-helix in a novel N-terminal extension.
2 ntiholin, S107, which differs by its Met-Lys N-terminal extension.
3 gth chains the groove is likely filled by an N-terminal extension.
4 sses a novel first exon that encodes a 51 aa N-terminal extension.
5 from restricted removal of the cTnI-specific N-terminal extension.
6 der of the pilus, with the assistance of the N-terminal extension.
7 hile RGS4-3 encodes a 302 aa protein with an N-terminal extension.
8 immunoglobulin-like fold (pilin body) and an N-terminal extension.
9 weakly stimulates motor domains without the N-terminal extension.
10 , a variant of TUC-4a that includes a unique N-terminal extension.
11 w ionic strength upon addition of this extra N-terminal extension.
12 obed the protein-protein interactions of the N-terminal extension.
13 be sensitive to the nature of the protruding N-terminal extension.
14 mally stabilized form of Mcl1 due to a 13-aa N-terminal extension.
15 odulates the actin binding properties of the N-terminal extension.
16 rel domain connected to a positively charged N-terminal extension.
17 interaction domains located at their unique N-terminal extension.
18 y unobserved HXH motif located in its unique N-terminal extension.
19 ke region and a approximately 400 amino acid N-terminal extension.
20 motif, but it also carries an arginine-rich N-terminal extension.
21 d MCM2 are unusual in having long and unique N-terminal extensions.
22 structure with structurally uncharacterised N-terminal extensions.
23 h contain the DNA binding domain and various N-terminal extensions.
24 RPs) contain a C-terminal RFamide but unique N-terminal extensions.
25 with DNA to analyse functional roles of the N-terminal extensions.
26 ic of other L23a family members and a unique N-terminal extension, absent from Saccharomyces cerevisi
27 g the HB-EGF membrane anchor, but lacking an N-terminal extension, activated EGFR during their transi
31 These and other results suggest that the N-terminal extension alters the accessibility of the sig
32 site of interaction of Mal3 with Tea2 is the N-terminal extension, although a weaker interaction is a
33 the channels include a 71 amino acid CLH-3a N-terminal extension and a 270 amino acid extension of t
36 ed in the KE-rich region at the start of the N-terminal extension and appears to mediate ATP-independ
37 -24 (also PKA sites) in the cardiac-specific N-terminal extension and at Thr-144, a unique residue in
38 ric Mdv1-Fis1 complex that contains both the N-terminal extension and coiled-coil regions of Mdv1.
39 Surprisingly, the commonly cited V2-specific N-terminal extension and cysteines were found to be disp
43 ecular autoinhibitory mechanism involving an N-terminal extension and phosphorylation of tyrosine res
44 verall architectural topology; however, each N-terminal extension and pilin body has specific functio
45 e intrasubunit interactions between the cTnI N-terminal extension and the cTnI inhibitory peptide, wh
46 ating intramolecular interaction between the N-terminal extension and the inhibitory region of cTnI.
47 ity to the intrinsic effects of Motif 3, the N-terminal extension and their synergistic effect, and (
48 up I intron binding surface that includes an N-terminal extension and two small insertions (insertion
49 on those of bacterial TyrRSs, except for an N-terminal extension and two small insertions not found
50 eptides from ERAAP-deficient cells contained N-terminal extensions and had a different molecular comp
51 These new compstatin peptides contain polar N-terminal extensions and non-natural amino acid substit
53 ), a histidine-tagged analogue containing an N-terminal extension, and five different terminus-trunca
54 interactions are lost after exit of the VP1 N-terminal extension, and that the RNA also interacts wi
55 ly of bacteria that contain MetAPs with such N-terminal extensions, and we classify these as MetAP ty
57 pe of a truncated form of DrDps1 without the N-terminal extensions appears as a dodecameric sphere, c
58 tor domain only or the motor domain plus the N-terminal extension are monomeric, whereas a construct
60 H16 that makes specific contacts with the S4 N-terminal extension, as well as a right-angle motif bet
64 ements of the zinc finger as well as a short N-terminal extension but is restricted to the switch and
66 ates the ATPase of constructs containing the N-terminal extension by decreasing the K0.5(MT) for stim
67 in vitro motility assay, suggesting that the N-terminal extension can act in a modular manner to incr
68 presence of calcium nor deletion of the MTIP N-terminal extension changed the speed of actin movement
71 lumen are synthesized in the cytosol with an N-terminal extension consisting of transient signals for
74 bacterial orthologs, plant UreGs possess an N-terminal extension containing a His- and Asp/Glu-rich
80 escued null or control (Dmlc2(+)), truncated N-terminal extension (Dmlc2(Delta2-46)), disrupted myosi
81 e is not sufficient for cytotoxicity and the N-terminal extension does not affect the conformation of
82 HK97, T5 encodes the scaffold function as an N-terminal extension (-domain) to the major head protein
83 nzymes, however, TgVP1 contains a 74-residue N-terminal extension encompassing a 42-residue N-termina
87 eal a 'budded' PH domain fold, possessing an N-terminal extension forming an integral part of the ove
88 aturally occurring 12-amino acid hydrophilic N-terminal extension found on s2 VacA blocks vacuolating
89 gondii lacks this type of translocator, the N-terminal extension from the Plasmodium falciparum sequ
90 rge spacer insert domain and a portion of an N-terminal extension function cooperatively to increase
91 cardiac stress to remove the unique cardiac N-terminal extension functions to improve cardiac contra
94 show that the native signal peptide, or any N-terminal extension, has an inhibitory effect on SplB.
96 on of an invariant asparagine residue in the N-terminal extension, however, restored cotranslational
97 ting evidence as to the functions of the BNP N-terminal extension; however, this has never been asses
98 led oxidation of Fe(2+), and possess a short N-terminal extension implicated in stabilizing cellular
99 ers of the ABCC subfamily, Ycf1p contains an N-terminal extension in addition to its ABC "core" domai
100 rough the ASTS USP7 binding motif within its N-terminal extension in an identical manner with other k
104 especially the role of the cardiac specific N-terminal extension in modulating actomyosin interactio
107 consensus sequence, and participation of the N-terminal extension in the formation of the substrate-b
110 Analysis of Trx h9 revealed a 17-amino acid N-terminal extension in which the second Gly (Gly(2)) an
111 ewly identified role of the ferritin subunit N-terminal extensions in gating Fe(2+) exit from the cyt
113 presentation of peptide precursors with long N-terminal extensions in TPPII gene-trapped embryonic fi
117 . smegmatis but included an eight amino acid N-terminal extension involving a different start codon.
118 Previous structural studies showed that the N-terminal extension is disordered in the absence of DNA
120 revented virus recovery, suggesting that the N-terminal extension is essential for virus viability.
121 Hydrodynamic analysis indicates that the N-terminal extension is in a highly extended conformatio
122 ding that the coding sequence for the entire N-terminal extension is omitted from the plasmid, transf
124 he molecules of the crystal, part of the RLC N-terminal extension is seen in atomic detail and forms
126 of available databases shows that the unique N-terminal extension is shared by multiple insect lineag
127 ed protein alpha-synuclein with a 10-residue N-terminal extension is shown to form a stable tetramer
128 2 ubiquitin conjugation enzyme with a unique N-terminal extension, is a novel USP7-interacting protei
129 ar-encoded as their precursors containing an N-terminal extension known as the transit peptide (TP).
130 activity of the protease precursor), and the N-terminal extension makes transient intra- and intersub
133 The active site at the interface of the N-terminal extension, methyltransferase, and beta-barrel
134 st other Ras family members, ARHI has a long N-terminal extension, modest GTPase activity, and consti
135 Additionally, the effect of one of the L3 N-terminal extension mutants on the interaction between
138 dgd1-1 mutant of Arabidopsis in fusion with N-terminal extensions (NDGD1 and NDGD2) targeting to the
139 Most strikingly, deletion of ARHI's unique N-terminal extension nearly abolished its inhibitory eff
140 that phosphorylation of Ser-251 in the Ycf1p N-terminal extension negatively regulates activity.
142 ted using specific primers with deletions of N-terminal extension (NT) (named betaA3-NT), N-terminal
143 nts of betaA3-crystallin were generated: (i) N-terminal extension (NTE) 21 amino acids (betaA3[21] mu
144 erminal localization module, organized in an N-terminal extension (NTE) and a tetratricopeptide repea
147 replaced with a beta-strand formed from the N-terminal extension (Nte) of an incoming pilus subunit
148 Here we demonstrate that the unstructured N-terminal extension (NTE) of ClpS enters the ClpA proce
149 aracterized by a approximately 32 amino acid N-terminal extension (NTE), the function of which remain
150 ransporters is the presence of a hydrophobic N-terminal extension (NTE), whose function is not clearl
153 binding and autophosphorylation, but has an N-terminal extension of 370 aa, lacking homology with an
154 catalytically active construct, including an N-terminal extension of 60 residues prior to the kinase
155 rocessed wild-type protein, which carries an N-terminal extension of 84 amino acids in the form of it
156 se that new gene overlaps generally arise by N-terminal extension of a downstream gene, creating a no
159 maltase with known structure and exhibits an N-terminal extension of about 140 residues, in contrast
161 change, occurring at the usher, in which the N-terminal extension of an incoming subunit completes th
162 nslated regions were noncanonical and led to N-terminal extension of annotated proteins or translatio
163 an thymidylate synthase (TS) enzymes have an N-terminal extension of approximately 27 amino acids tha
164 ion (ECF) sigma factor PvdS but possesses an N-terminal extension of approximately 29 amino acids tha
165 llins were modified by removal of either the N-terminal extension of betaA3 (rbetaA3Ntr) or betaB2 (r
168 Overall, our results demonstrate that the N-terminal extension of BNP is essential to virus viabil
170 covered phosphorylation sites located in the N-terminal extension of cardiac troponin I (S4, S5, Y25)
173 These findings indicate that removal of the N-terminal extension of cTnI via restricted proteolysis
178 nd proline-rich ligands, we suggest that the N-terminal extension of ELC interacts with actin and mod
181 our data support that the mRNA encoding the N-terminal extension of hcArgRS has the capacity of inde
182 the DNA-binding domain of GAL4 fused to the N-terminal extension of HDAC5 and the VP16 transcription
184 taining filaments, the DFRXXL motifs and the N-terminal extension of long MLCK confer high affinity b
188 donor strand exchange mechanism in which the N-terminal extension of one subunit replaces the chapero
194 the myristoylated capsid protein VP4 and the N-terminal extension of the capsid protein VP1, both of
195 orthologues of Zta suggest that a conserved N-terminal extension of the consensus B-ZIP domain is re
196 he SH3 domain facilitates the binding of the N-terminal extension of the essential light chain isofor
198 nsect cells is multiply phosphorylated on an N-terminal extension of the protein that contains a high
200 domains of TnC, providing evidence that the N-terminal extension of TnI interacts with the N-termina
201 additional E2-E3 interaction mediated by the N-terminal extension of UbcH10 regulates APC activity.
202 degradation by polypeptides that include the N-terminal extension of VP1 and capsid protein VP4.
203 ggregation kinetics of Abeta42 variants with N-terminal extensions of 5-40 residues, and transmission
204 and indicated that truncation occurs within N-terminal extensions of beta-crystallins during lens ma
206 of a set of conserved serine residues in the N-terminal extensions of class II HDACs creates binding
211 EF loop of VP2, the GH loop of VP3, and the N-terminal extensions of VP1 and VP2, which, in retrospe
213 ucleotide exchange activity requires a novel N-terminal extension on the DH domain that is predicted
215 ha is soluble, either phosphorylation of its N-terminal extension or DNA binding promotes the formati
216 trate that L27 variants with an un-cleavable N-terminal extension, or lacking the extension (pre-clea
217 N-terminal extension (NT) (named betaA3-NT), N-terminal extension plus motif I (named betaA3-NT + I),
218 xtension plus motif I (named betaA3-NT + I), N-terminal extension plus motifs I and II (named betaA3-
219 ning dimers, tetramers and octamers, but the N-terminal extension present in IncC1 favours nucleotide
220 efining a subtilisin-like fold with a unique N-terminal extension previously proposed to function as
221 of human PDE3A1 at a PKA site in its unique N-terminal extension promotes its incorporation into SER
222 -ray scattering (SAXS) results show that the N-terminal extensions protrude from the spherical shell
223 e new subunits were dictated by the specific N-terminal extension provided and were consistent with t
228 antibody directed against the alpha-subunit N-terminal extension region or by deletion of the N-term
230 nuclear localization of BNP, with the entire N-terminal extension required for this to function effic
231 cal PTP domain (residues 44-339) and a short N-terminal extension (residues 1-43) that functions to d
232 l (betaalpha)6-barrel fold with a disordered N-terminal extension (residues 45-74) and a partially or
233 nsion of this peptide has little effect, but N-terminal extension results in higher maximal velocity
235 including a short C-terminal tail and a long N-terminal extension rich in prolines, alanines, and lys
236 E. coli or spinach counterparts, containing N-terminal extensions (S2 and S5) or insertion sequence
237 at Cul3 interaction is dependent on a unique N-terminal extension sequence that packs against the 3-b
238 the structure uncovers a unique role for the N-terminal extension sequence, which stabilizes helix al
239 lls, with a lysine in the non-ubiquitin-like N-terminal extension serving as the major SUMO-SUMO bran
241 nscriptional regulators and also contains an N-terminal extension similar to the Ni(2+)-binding C-ter
242 duced after radiation damage and contains an N-terminal extension similar to those of proteins involv
244 st likely due to cellular recognition by the N-terminal extension, since the intrinsic activity of th
245 during autoactivation at higher pH contained N-terminal extensions (starting at 6 and 14 amino acid r
246 ra crassa MMM1, which naturally lacks a long N-terminal extension, substituted for loss of Mmm1p in b
247 ophobic cleft while two other helices and an N-terminal extension target a discrete surface formed la
248 v1 has a modular structure, consisting of an N-terminal extension that binds Fis1, a central coiled c
249 approximately 150 amino acids as well as an N-terminal extension that consists of two carbohydrate b
250 I isoforms, cardiac troponin I (cTnI) has an N-terminal extension that contains phosphorylation sites
251 troponin I (cTnI) isoform contains a unique N-terminal extension that functions to modulate activati
252 transcription, the Ton box is preceded by an N-terminal extension that interacts with the inner-membr
253 ns an evolutionarily conserved 50-amino-acid N-terminal extension that is absent from the NP of influ
254 C-terminal domain found in RecA, but have an N-terminal extension that is absent in the RecA protein.
255 e only identified mutation within its unique N-terminal extension that is associated with hypertrophi
256 resembles a classical signal peptide plus an N-terminal extension that is conserved in other autotran
257 reus and other Firmicutes is encoded with an N-terminal extension that is not present in most Gram-ne
258 unit protein L27 is encoded with a conserved N-terminal extension that is removed to expose residues
259 inactive mini-precursor with a four-residue N-terminal extension that mimics the transframe region p
260 family members, the neuronal protein has an N-terminal extension that shares characteristics of yeas
261 D contains an approximately 170-residue-long N-terminal extension that structurally mimics a dimer-di
262 find that TatA in Prov. stuartii has a short N-terminal extension that was atypical of TatA proteins
265 c structural elements (a beta hairpin and an N-terminal extension) that contribute to its substrate s
266 e nuclear localization signal (NLS) in their N-terminal extension, the 18-kDa FGF-2 does not contain
267 ith the exception of a unique 129-amino acid N-terminal extension, the ACH2 protein is 17-36% identic
268 letion constructs were prepared in which the N-terminal extension, the C-terminal extension or both e
269 include a zinc-binding site and a hook-like N-terminal extension, the latter representing a hallmark
270 pFurH134Y), which represent mutations in the N-terminal extension, the regulatory metal binding site
271 As the NP of influenza A virus lacks this N-terminal extension, these viruses may have evolved sep
272 o process viral peptides with C-terminal and N-terminal extensions through their proteasomal and cyto
273 cific E2-E3 interface and regulation via its N-terminal extension to limit APC activity for substrate
276 ted data reveal the relative position of the N-terminal extensions to the dodecameric sphere in solut
277 s to the trimming of peptides with very long N-terminal extensions, TPPII is not essential for genera
279 diminished power output parameters with the N-terminal extension truncation and phosphorylation site
281 f both N- and C-terminal tails, but only the N-terminal extension undergoes mechanical removal, there
284 In this study, pilus subunits in which the N-terminal extension was either deleted or swapped with
286 ted by proteolytic processing and lacked the N-terminal extension was unable to bind fibrinogen.
287 C) and the physiological significance of its N-terminal extension, we generated transgenic (Tg) mice
288 nuclein construct that contains a 10-residue N-terminal extension, which forms multimers when isolate
289 DFRXXL motifs and six Ig-like modules in an N-terminal extension, which may confer unique binding pr
290 conserved among bacteria containing the L27 N-terminal extension, which performs post-translational
292 f actomyosin, through the interaction of its N-terminal extension with actin and its C-terminal lobe
294 fide transporter, CcdA, which all display an N-terminal extension with respect to their bacterial cou
295 locating within the protein, or swapping its N-terminal extension with that of other subunits altered
297 Saccharomyces cerevisiae ProRS possesses an N-terminal extension with weak homology to a bacterial-s
298 s, which we named AtRibF1 and AtRibF2, carry N-terminal extensions with characteristics of organellar
299 to 5-FCLs of other organisms but containing N-terminal extensions with the features of mitochondrial
300 ble tolerance for accommodating the fly L23a N-terminal extension within the structure of the yeast r
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