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1 ng either the entire L11 protein or just the N-terminal portion.
2 -binding domain was situated in the flexible N-terminal portion.
3 in with the virion components located in the N-terminal portion.
4 as a putative DNA helicase is encoded by the N-terminal portion.
5 mbrane NRG isoforms with this CRD within the N-terminal portion.
6 inding, one on the C-terminal and one on the N-terminal portion.
7 the presence of STIM1 and the conserved Orai N-terminal portion.
8 tion of the p21 core protein and lacking the N-terminal portion.
10 ptually subdividing 1 into three regions: an N-terminal portion, a central statine-containing core, a
12 with truncated Prx1 proteins showed that the N-terminal portion and the homeodomain of Prx1 were nece
13 of proteins containing the PDZ domain in the N-terminal portion and the LIM domain in the C-terminal
14 ly targeted to the nucleus by signals in its N-terminal portion, and the full-length protein accumula
16 ernal leader could function even if the most N-terminal portion contained negative charges in the fir
17 osed of two subdomains, a largely disordered N-terminal portion containing three known phosphorylatio
18 raged 55 +/- 2%, suggesting that the missing N-terminal portion contains most of the alpha-helical st
20 nce of a VHS (Vps27p/Hrs/Stam) domain in the N-terminal portion followed by a GAT (GGA and Tom) domai
21 the levels of cellular LRP and releases its N-terminal portion in the extracellular milieu while the
22 MD simulations suggested that the remaining N-terminal portion in the non-functional Orai1 N-truncat
23 two sets of constructs were created in which N-terminal portions (including either VRI-IV or only VRI
25 alone revealed low deuteration levels in the N-terminal portion, indicating that this region containe
26 cytoplasmic tail, PKD1(115-226), but not the N-terminal portion, induced a large, Ca(2+)-permeable ca
27 portion is essential for clipping, while the N-terminal portion is sufficient for DSB end-resection.
28 c(y) revealed that its signal sequence-like N-terminal portion is uncleaved; hence, it is anchored t
30 al analyses it is shown that domain C of the N-terminal portion, located adjacent to the helicase cat
31 n in muscle and adipose tissues and that its N-terminal portion may be critical for APPL1 function.
32 either in small proteins, or it makes up the N-terminal portion of a larger protein, usually a protei
33 of our peptide sequences and represented the N-terminal portion of a protein containing a signal pept
35 of AHR transactivation by AHRR involves the N-terminal portion of AHRR; does not involve competition
38 rt of the binding pocket that recognizes the N-terminal portion of alpha-factor and is involved in th
39 erminal tail (residues 1-9), followed by the N-terminal portion of alpha-helix 1 (residues Cys-11, Gl
45 d region (sigma(70) NCR) and a region in the N-terminal portion of beta' that appears to functionally
46 study, we used a monoclonal antibody to the N-terminal portion of beta-APP to examine how the immuno
49 es and a conserved hydrophobic region in the N-terminal portion of BovK sensor domain were important
52 -C/EBP-epsilon antibodies raised against the N-terminal portion of C/EBP-epsilon (amino acids 1 to 11
53 BPepsilon and fusion proteins containing the N-terminal portion of C/EBPepsilon, whereas PIASxalpha w
54 The complete HelX protein and the soluble N-terminal portion of Ccl2 (called Ccl2*) were overprodu
56 olypeptide of 24-25 kDa corresponding to the N-terminal portion of D1 that is unstable and appears to
58 nd that mu1 autocleavage is regulated by the N-terminal portion of delta, which forms an alpha-helica
62 precursors demonstrated that the lack of the N-terminal portion of FE65, which includes part of the f
63 n-bond stabilised secondary structure in the N-terminal portion of fH module 16, and the number and t
66 around the fluorescein, suggesting that the N-terminal portion of galanin, which constitutes the bin
68 MAbs (including H6 and 37S) reacted with the N-terminal portion of gH between amino acids 19 and 276.
69 a series of chimeric peptides combining the N-terminal portion of GLP-1 or Ex-4 and the C-terminal s
70 mbinant vaccinia viruses expressing only the N-terminal portion of gp160, containing P18 but not HP53
71 One neurovirulence determinant mapped to the N-terminal portion of gp7O, which contains the VRA and V
73 the STAT1 interaction domain resides in the N-terminal portion of HCV core (amino acids [aa] 1 to 23
74 oligomers in vitro and in vivo and that the N-terminal portion of HDAC3 is necessary for this proper
75 g site together with five differences in the N-terminal portion of helix I conferred S-mephenytoin 4'
76 1, the C-terminal portion of helix-2 and the N-terminal portion of helix-3, bounded by the intramolec
77 rkness, indicating that the COP1-interacting N-terminal portion of HFR1 is essential for COP1-mediate
79 the three-dimensional structure of a 22-kDa N-terminal portion of human eIF2alpha by x-ray diffracti
80 a protein shares sequencesimilarity with the N-terminal portion of human PCAF that is involved in bin
81 AT1aR replaced the HK of BKB2R, leaving the N-terminal portion of IC1 without a positively charged r
82 t two overlapping regions within the central N-terminal portion of ICP0 (residues 212 to 311) promote
83 n region I, termed Phos 1, which lies in the N-terminal portion of ICP0, impairs the E3 ubiquitin (Ub
85 or binding to GC-rich sequences and that the N-terminal portion of ICP27 is highly flexible in struct
86 er, our results suggest a model in which the N-terminal portion of ICP27 mediates a nonessential acti
88 is of IE1 regulatory domains, the M1 to T266 N-terminal portion of IE1 was subdivided (on the basis o
90 e describe a refined model of the alpha(IIb) N-terminal portion of integrin alpha(IIb)beta(3) obtaine
92 s T-antigen binding was localized within the N-terminal portion of IRS-1 molecule, and the binding wa
93 lice variants which encode proteins with the N-terminal portion of K-bZIP but lacking the C-terminal
98 erved amino acid residues indicated that the N-terminal portion of LasR is required for multimerizati
99 ate that a fusion protein of the ACD and the N-terminal portion of lethal factor from Bacillus anthra
101 d and positively charged residues within the N-terminal portion of MA constitute the membrane-binding
102 LS (FUS) and the related gene EWS encode the N-terminal portion of many fusion oncoproteins involved
103 o an unanticipated trans-acting role for the N-terminal portion of matrix in the formation of stable
104 110 kDa extracellular protein represents the N-terminal portion of mature Hap (designated Haps).
105 ex reveals that 3A6 primarily recognizes the N-terminal portion of MBP, in contrast with antimicrobia
107 d the interacting regions were mapped to the N-terminal portion of menin and amino acids 43 to 171 of
114 tion occurs on the cytoplasmically localized N-terminal portion of NDR1 and that this interaction is
117 izes to the nucleus and that a region in the N-terminal portion of Notch(IC), not the six ankyrin rep
118 rmal tissues, the two antibodies against the N-terminal portion of NPM labeled the cytoplasm of neopl
119 of which recognize, by Western blotting, the N-terminal portion of NPM present in the NPM-ALK fusion
121 al locus is inhibited in cells producing the N-terminal portion of Nuc from a multicopy plasmid.
123 encing, while protease p48, derived from the N-terminal portion of ORF B, is required for viral RNA r
125 The p50 protein is incorporated within the N-terminal portion of p105 and is a unique product of pr
126 utant Cdc37 gene products indicated that the N-terminal portion of p50(cdc37) interacted with immatur
134 al assembly domain (the M domain) within the N-terminal portion of Pr55Gag mediates the interaction o
135 ing epitopes located within the unstructured N-terminal portion of PrP(C) and those recognizing epito
137 overall data support the hypothesis that the N-terminal portion of PTH is alpha-helical when bound to
138 N-terminal cleavage fragment shows that the N-terminal portion of Rad9 localizes in the cytosol, bin
141 5 weakens the direct association between the N-terminal portion of RbC (RbC(N)) and the marked-box do
143 - or C-terminal deletions, we found that the N-terminal portion of RepA is required for recognition.
144 all of which are prenylated, as well as the N-terminal portion of retinitis pigmentosa GTPase regula
147 ction with a 75-kD protein (p75) required an N-terminal portion of RPS2 that is smaller than the regi
149 lowing cleavage by the unknown protease, the N-terminal portion of RsiV requires further processing,
150 ocation has 752 amino acids and contains the N-terminal portion of RUNX1 (also known as AML1, CBFalph
153 have determined the crystal structure of the N-terminal portion of SHARPIN, which adopts the highly c
157 show that the coiled-coil region within the N-terminal portion of SS4 is involved in both processes.
161 ionic interactions was found to connect the N-terminal portion of the 8th helix to the nearby NPXXY
164 D/H polymorphism at residue 216 falls in the N-terminal portion of the AAA+ domain near the sensor 1
165 y, WH2 shares structural similarity with the N-terminal portion of the actin monomer-sequestering thy
166 rypsin-resistant peptide did not include the N-terminal portion of the AhR against which the antibody
170 ibe a small set of amino acid sites from the N-terminal portion of the basic helix-loop-helix (bHLH)
171 The most pronounced difference is in the N-terminal portion of the beta4-beta5 loop, which is str
173 CBR inhibitors target a crevice between the N-terminal portion of the bridge helix and a surrounding
174 n appendage domain that is inserted into the N-terminal portion of the catalytic domain, and a C-term
176 nt from Asn1 to Ala7 (denoted domain 1), the N-terminal portion of the collagen domain from Gly8 to G
177 gion or interchain disulfide linkage; 2) the N-terminal portion of the collagen-like domain is requir
178 o species, reveal that the EGF motif and the N-terminal portion of the cytoplasmic domain are importa
181 hydrophobic groove, which interacts with the N-terminal portion of the divergent IQ1 and IQ2 motifs.
183 genous protein that is highly related to the N-terminal portion of the FeLV envelope protein, which i
184 he CD44-binding site is localized within the N-terminal portion of the fibrin beta chains, including
186 p120, and molecular dynamics showed that the N-terminal portion of the fusion peptide can be solvent-
187 cell-cell fusion mechanism and show that the N-terminal portion of the gH cytotail is critical for th
188 op participates in communication between the N-terminal portion of the helicase and the C-terminal ca
190 e papain-like protease p29, derived from the N-terminal portion of the hypovirus CHV1-EP713-encoded o
191 n M3R dimer that was cross-linked within the N-terminal portion of the i3 loop (264C) was functionall
193 Q2N antibodies, directed against a conserved N-terminal portion of the KCNQ2 polypeptide, to localize
195 esidue 19, contribute to the capacity of the N-terminal portion of the ligand to interact with the ju
199 uggest that the delta subunit N terminus and N-terminal portion of the M1 domain are, at least in par
200 respect to amino acid residue charge in the N-terminal portion of the mature protein has occurred re
202 we determined the solution structure of the N-terminal portion of the MCM complex from the archaeon
205 ect ovarian Sf9 cells induced to express the N-terminal portion of the molecule form MT-rich processe
206 nic interactions, localized primarily in the N-terminal portion of the molecule, enhance the stabilit
207 pterin aldolase function is expressed as the N-terminal portion of the multifunctional folic acid syn
208 of the Rel homology domain (RHD) within the N-terminal portion of the NF-kappa B 1 protein is requir
209 , which normally generates p50, degrades the N-terminal portion of the NF-kappa B 1 protein when the
211 encode one methyltransferase, located at the N-terminal portion of the NS5 protein, to catalyze both
212 st two-hybrid system indicated that only the N-terminal portion of the p-55 domain is required for p-
215 , in which the Bpa residue is located in the N-terminal portion of the peptide, was used to define fu
216 rther assess the functional relevance of the N-terminal portion of the perforin molecule in its lytic
220 38), Cys(48), Cys(70), and Cys(72)] with the N-terminal portion of the potyvirus-encoded helper compo
222 om the membrane bilayer, suggesting that the N-terminal portion of the presequence is essential for m
223 ation of a fusion protein (PF-MC) made up of N-terminal portion of the protease inhibitor Trappin-2 (
224 onstrate that despite massive changes in the N-terminal portion of the protein and in the DNA upstrea
226 eral SHANK3 missense mutations affecting the N-terminal portion of the protein by expression of wild-
228 region of Rgt1 physically interacts with the N-terminal portion of the protein that includes the DNA-
230 gnal and was secreted by the T4SS, while the N-terminal portion of the protein was not secreted.
231 n Methanothermobacter thermautotrophicus the N-terminal portion of the protein was shown to be involv
232 Substitution of leucine for Lys-61 in the N-terminal portion of the protein, however, abolished th
233 requires the Acidic blob (AB) region in the N-terminal portion of the protein, indicating that the A
234 on sites of ICP27 appeared to cluster in the N-terminal portion of the protein, such that a frameshif
236 r the archaeal protein it was shown that the N-terminal portion of the protein, which is composed of
242 nist, a synthetic lipopeptide comprising the N-terminal portion of the putative Mycobacterium leprae
245 ently developed a shortened CFTR missing the N-terminal portion of the R domain (residues 708-759, CF
246 on interaction with vitronectin, whereas the N-terminal portion of the reactive loop does not experie
248 8)] is further divided into N-terminal [RS1: N-terminal portion of the RS domain (residues 198-227)]
249 RPK1 has been shown to polyphosphorylate the N-terminal portion of the RS domain (RS1) of the SR prot
251 ion of a short stretch of amino acids in the N-terminal portion of the RS domain of ASF/SF2 while Clk
253 ct E36 cells, whereas vectors containing the N-terminal portion of the SSAV SU protein and C-terminal
254 transmembrane domain 5 (TM5) and within the N-terminal portion of the third intracellular loop (i3 l
257 es and limited proteolysis revealed that the N-terminal portion of the unassembled subunit is meta-st
258 raised against a repetitive sequence in the N-terminal portion of the WND molecule detects an additi
259 breakdown was inhibited by TIMP-1 or by the N-terminal portion of TIMP-3, although FGF-2 did not aff
260 ) binds to ssRNA, our studies imply that the N-terminal portion of TLR7 triggers a yet to be identifi
261 e compatible with involvement in vivo of the N-terminal portion of troponin I in enhancing force prod
262 1 and a CD36 agonist antibody but not by the N-terminal portion of TSP1, suggesting that CD36 or a re
263 howed that the complete TUSP protein and the N-terminal portion of TUSP are localized in the cytoplas
264 either the C-terminal portion of UCR1 or the N-terminal portion of UCR2 abolishes dimerization of PDE
265 coimmunoprecipitation assay to show that the N-terminal portion of UL9 can indeed directly interact w
273 t a characterization of the structure of the N-terminal portion of yeast Sac1, containing the conserv
274 A interaction are mapped, revealing that the N-terminal portion of YY1 (amino acids 1-300) and the DN
276 e yeast two-hybrid system indicates that the N-terminal portions of cotton fiber GhCesA1 and GhCesA2
278 Kinetic and NMR studies thus reveal that the N-terminal portions of FXIII AP (28-37) (V34 and V34L) a
284 en fluorescent protein (GFP)- or FLAG-tagged N-terminal portions of the Htt protein containing either
285 S. pneumoniae ClpXP in vivo, even though the N-terminal portions of the tags differ significantly bet
289 ll-down assay suggests an association of the N-terminal portion (Phe(120)-Phe(187)) of the D2 loop wi
294 r membrane protein with a long extracellular N-terminal portion that bears several ligand-binding dom
295 hatase activity and a proteolytically labile N-terminal portion that functions to enhance the affinit
297 partite architecture consisting of a soluble N-terminal portion (TprC(N)), presumably periplasmic and
299 zed by a conserved tripartite motif in their N-terminal portion which comprises a canonical RING doma
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