ライフサイエンスコーパス: N-terminal region

1 cent segment (positions 61-67) in the FLIL33 N-terminal region.

2 tremely transient helices are present in the N-terminal region.

3 Lhcb1 and Lhcb2 can be phosphorylated in the N-terminal region.

4 ike domain at the C terminus and an extended N-terminal region.

5 hanges of negatively charged residues of the N-terminal region.

6 ssociated with conformational changes in the N-terminal region.

7 ly by the presence of a unique extracellular N-terminal region.

8 rom the presence of an acidic residue at its N-terminal region.

9 rimental evidence of O-linked glycans in the N-terminal region.

10 binding protein C (cMyBP-C), focusing on the N-terminal region.

11 tructure of a stable domain (CHD4-N) in this N-terminal region.

12 activity, and a functionally uncharacterized N-terminal region.

13 clease domain, but instead binds to the EsaD N-terminal region.

14 es against Plasmodium should include the CSP N-terminal region.

15 yte-binding domains were mapped within their N-terminal regions.

16 comprising a long multidomain extracellular N-terminal region, 11 transmembrane regions, and a short

17 ects the nucleus to the cytoskeleton via its N-terminal region [5-7].

18 , we determined the crystal structure of the N-terminal region (599-627) of the catalytic subunit Swr

19 beta8.1, 8.2(+) immune T cells recognize the N-terminal region (aa 41-152) of dense granule protein 6

20 Here, we report that the E1A N-terminal region also interacted with the cellular prot

21 P1BP3 to chromatin depends on both its C and N terminal regions and is affected by the cell cycle and

22 The DeltaN-LKB1 protein lacks the N-terminal region and a portion of the kinase domain.

23 onal analysis suggests the involvement of an N-terminal region and a proximal C-terminal region that

24 d of two monomers that each contain a folded N-terminal region and an intrinsically disordered C-term

25 Because the N-terminal region and first transmembrane domain of the

26 tional ensembles of the partially disordered N-terminal region and interhelical loop.

27 Hsc70 dynamically associated with the N-terminal region and Rac1 GEF domain of Trio.

28 these nuclear structures is mediated by the N-terminal region and requires prion-like activity.

29 ed form higher-order oligomers through their N-terminal region and that the same AT-rich site is reco

30 The results show that the N-terminal region and the C-terminal unstructured loop u

31 two structured regions of Raptor: one in the N-terminal region and the other in the C-terminal region

32 midinic (AP) site processing, one within the N-terminal region and the second within the C-terminal d

33 tions in GNPTAB uncovered amino acids in the N-terminal region and within the DMAP domain involved in

34 AF-1 is localized in the N-terminal region, and AF-2 is distributed in the C-term

35 2/26) were recurrent mutations affecting the N-terminal region, and another 38.5% (10/26) affected th

36 ective groups of hnRNP proteins, through its N-terminal region, and directly regulates pre-mRNA splic

37 changes that affect the solvent exposure of N-terminal region, and hence the redox sensitivity of th

38 molecular rationale for the function of the N-terminal region, and support the idea that Cerberus co

39 so cleaved to a truncated peptide within its N-terminal region (Arg(289) downward arrowLys(290)).

40 itinating activity, revealing a role for the N-terminal region as a regulatory module in the control

41 f-mediated cleavage mechanism, featuring the N-terminal region as an anchor for at least one of the D

42 i activation required not only the conserved N-terminal region but also permissive communication of t

43 0, 39, 47, and 57, that are clustered in the N-terminal region but not at lysines in the oligomerizat

44 a protein that may be cleaved in vivo at the N-terminal region by neutrophil proteases including elas

45 same time to control the flexibility of the N-terminal region by the disulfide bond formed between c

46 Thus, the variable N-terminal region can define the spectrum of viruses inh

47 linear extension of the filament, while the N-terminal region can serve as a branch-point.

48 ased rates of MT polymerization, whereas the N-terminal region cannot bind to MT plus ends but can ac

49 One class of mutants defined an RssB N-terminal region close to the phosphorylation site and

50 is the presence of two conserved regions: an N-terminal region codifying for signal peptide and a C-t

51 allographic structure of the Arabidopsis TPL N-terminal region comprising the LisH and CTLH (C-termin

52 We also show that the N-terminal region, conserved across all group 4 LEA prot

53 und to involve conformational changes in the N-terminal region consistent with a central role of this

54 the C-terminal region rather than the nearby N-terminal region, consistent with an allosteric effect

55 e, which encodes the previously undiscovered N-terminal region consisting of PHD and HMG domains and

56 he three-dimensional structure of the Xyn10C N-terminal region, containing the xylan-binding CBM22-1-

57 Here, we demonstrate that this N-terminal region contains a ubiquitin (Ub)-associated (

58 t that phosphorylation of HIP1 by RTKs in an N-terminal region contributes to the promotion of cellul

59 on of Ser-66 in the intrinsically disordered N-terminal region decreases the interaction strength wit

60 In a truncated form of GRK1 lacking the N-terminal region (DeltaN-GRK1), peptides that directly

61 We confirm that the N-terminal region directly inhibits the kinase activity

62 Mutations in the whirlin N-terminal region disrupted FL-whirlin isoform in the in

63 rthermore, we found that deletion of the F1L N-terminal region does not impede F1L antiapoptotic acti

64 by leucine-rich repeats (LRRs) and having an N-terminal region enriched in alternating lysine and glu

65 nd the gelatin-binding domains of the 70-kDa N-terminal region (FN70K).

66 ball and tether, consisting of a disordered N-terminal region followed by a compact globular C-termi

67 shows that AGR2 consists of an unstructured N-terminal region followed by a thioredoxin fold.

68 The primate betaherpesvirus conserved N-terminal region from aa 1 to 71 is sufficient to fully

69 CYP1A2, containing the N-terminal regions from CYP1A1, no longer localized in o

70 and release the processed Nrf1 (lacking its N-terminal region) from the ER, which allows it to enter

71 When not phosphorylated, this N-terminal region functions as an autoinhibitory domain

72 ene transcription, whereas FLASH through its N-terminal region functions in 3' end processing of hist

73 ngement of RNA-binding sites, although these N-terminal regions have only limited sequence conservati

74 f leucine-rich repeats domain also binds the N-terminal region, highlighting a possible mechanism for

75 munodominant B cell epitope derived from the N-terminal region I and to repeat sequences representing

76 Nase R, whereas the Walker B motif is in its N-terminal region implying that the two parts of the pro

77 to regulate DNA-damage responses through its N-terminal region in a poly(ADP-ribose) polymerase-depen

78 demonstrate that the established role of the N-terminal region in dimerization is not conserved; inst

79 how that three phosphorylated residues in an N-terminal region in Mtrm are required for Mtrm::Polo bi

80 er are partially understood, the role of the N-terminal region in the metazoan replicative mtDNA heli

81 Gelsolin fragments encompassing N-terminal regions in polypeptides of different molecula

82 The N-terminal region inserts into the lipid bilayer and app

83 folded side of the main barrier in which the N-terminal region is disordered.

84 site-directed mutagenesis, we show that the N-terminal region is essential for ADP-ribosylating acti

85 ed chromatin-stimulated ATPase activity, the N-terminal region is required for ATP-dependent chromati

86 Ku70/80 and DNA, further supporting that the N-terminal region is required for binding to the Ku-DNA

87 A highly conserved N-terminal region is required to bind dynein and kinesin

88 the NS2/NS3 junction, NS2, primarily via its N-terminal region, is also involved in virion morphogene

89 conserved membrane-proximal amino-terminal (N-terminal) region, is distinct from other lipid-activat

90 pper-dependent conformational changes in the N-terminal region lead to hyperphosphorylation at C-term

91 While loss of the N-terminal region leads to enhanced chromatin-stimulated

92 he best-scoring receptor structures have the N-terminal region lid region bound in a helical conforma

93 channel that otherwise binds ppGpp, and its N-terminal region, like the coiled-coil tip of DksA, eng

94 alyses over the N terminus revealed that the N-terminal region may also harbor a subfamily recognitio

95 Collectively, the results show the N-terminal region mediates the interaction between DNA-P

96 Results show that the N-terminal region needs to be inserted in the lipid memb

97 CaBP1 binds via its C lobe to the cytosolic N-terminal region (NT; residues 1-604) of InsP3R1.

98 Notably, an extended N-terminal region (NTR) consisting of 11 amino acids was

99 not a component of mature fibrils, the PMEL N-terminal region (NTR) is essential for their formation

100 e of an auto-regulatory motif, AutoN, in the N-terminal region (NTR) of ISWI, indicating that AutoN d

101 In contrast, the N-terminal region (NTR) of PARP-1 is over 500 residues a

102 kinetic techniques to show that the myosin-I N-terminal region (NTR) plays a critical role in tuning

103 ure shows the stalk region and the essential N-terminal region (NTR) previously unseen in our DNA unb

104 revealed that PA2588 has a novel fold at the N-terminal region (NTR), and its C-terminal HTH (helix-t

105 ed that DHX29 comprises a unique 534-aa-long N-terminal region (NTR), central catalytic RecA1/RecA2 d

106 ), a central Trp-Gly-Arg (WGR) domain and an N-terminal region (NTR).

107 ly spliced isoforms, differing only in their N-terminal regions (NTRs).

108 at serine 8 causes structural changes in the N-terminal region of Abeta aggregates in favor of less c

109 and other biological events that involve the N-terminal region of Abeta aggregates.

110 ough sequential truncation, we show that the N-terminal region of Abeta contributes to the enhanced f

111 modeling revealed that two residues near the N-terminal region of alpha-helix 1 in GPPrP might mediat

112 Moreover, we showed that the N-terminal region of alpha-syn is important for PLK2-med

113 Glycation affected primarily the N-terminal region of alpha-synuclein, reducing membrane

114 ions to refine structure and topology of the N-terminal region of alphaS bound to the surface of syna

115 shift perturbation analysis reveals that the N-terminal region of an MHV N SR-rich linker peptide (re

116 Surprisingly, the N-terminal region of Asl is not required for centriole d

117 ATXN7L3B shares 74% identity with the N-terminal region of ATXN7L3, but the functions of ATXN7

118 B0238, which specifically interacts with the N-terminal region of BB0323.

119 h ankyrin repeats (ANK) 1, 6, and 7, and the N-terminal region of Bcl-3.

120 The N-terminal region of BubR1 binds to both Cdc20 and Mad2,

121 Arf3p binds directly to the N-terminal region of Bud2p and promotes its GAP activity

122 Interestingly, the N-terminal region of C16 is predicted to have a PHD2-lik

123 by binding of the Hsp90 middle domain to an N-terminal region of Caenorhabditis elegans Cdc37 (CeCdc

124 These results define the N-terminal region of CAV1 as the critical ubiquitin conj

125 g the MCP-1 mutants showed that the sulfated N-terminal region of CCR2 binds to the same region (N-lo

126 eriments, sulfated peptides derived from the N-terminal region of CCR2 bound to both the monomeric an

127 We further identified a conserved N-terminal region of CDH23-C that binds to the CKK domai

128 We also show that the N-terminal region of CHD2, which contains tandem chromod

129 We also show that the N-terminal region of CHD4, although not CHD4-N alone, is

130 fy a cluster of phosphorylation sites in the N-terminal region of Crb2(53BP1) that mediate interactio

131 t a structural description of the Fn binding N-terminal region of CshA, derived from a combination of

132 ational analysis predicted that the extended N-terminal region of CYP144A1-FLV is largely unstructure

133 The N-terminal region of DNA-binding domain of STAT3 is resp

134 compared with DNA-PKcs, suggesting that the N-terminal region of DNA-PKcs keeps basal activity low.

135 ion at Y102 disrupts the helical fold of the N-terminal region of E2 and its interaction with key cel

136 re we show that the intrinsically disordered N-terminal region of E7 from high-risk HPV16 binds the T

137 We show that the N-terminal region of E9, which has sparse contacts with

138 In this study, we discovered that the N-terminal region of Efb (Efb-N) promotes platelet bindi

139 e non-synonymous substitution (A120G) in the N-terminal region of eIF2Bbeta was responsible for the T

140 the C terminus of Evasin-1, but through the N-terminal region of Evasin-4.

141 le played by a stretch of 17 residues in the N-terminal region of EZH2, we call the activation loop,

142 t Lsm11, in addition to interacting with the N-terminal region of FLASH, also contacts the C-terminal

143 Thus, the N-terminal region of FMDV 3D that acts as a nuclear loca

144 action between recombinant Mzt1/Tam4 and the N-terminal region of GCP3(Alp6).

145 The N-terminal region of GPR107 is critical for its biologic

146 l characterization of the previously unknown N-terminal region of HAI-1, we provide new insight into

147 ne "HIP1 phosphorylation motif" (HPM) in the N-terminal region of HIP1 that is required for phosphory

148 tation experiments, we demonstrated that the N-terminal region of HNF6 was responsible for its inhibi

149 An N-terminal region of HopK1 shares similarity with the co

150 Here, we present the structure of the N-terminal region of human BCAP and show that it possess

151 -L in the endoplasmic reticulum (ER) via the N-terminal region of human invariant chain p33, with or

152 to be important for biological activity: the N-terminal region of human neuropeptide Y (NPY1-9, Tyr(1

153 e rate of amyloid formation, even though the N-terminal region of IAPP is believed to be flexible in

154 During early mitosis, the N-terminal region of INCENP forms a three-helix bundle w

155 The N-terminal region of LANA binds histones H2A and H2B to

156 enolase activity, indicating that an intact N-terminal region of LOS2 is critical for catalysis.

157 munoprecipitated the recombinantly expressed N-terminal region of LRP2.

158 We show that the N-terminal region of MBNL1, containing its four CCCH zin

159 the interaction domain with Mec3 within the N-terminal region of Mcm10 and demonstrate that its trun

160 TFAM tethers the N-terminal region of mtRNAP to recruit the polymerase to

161 sharp contrast, recombinant proteins of the N-terminal region of MUC5B (D1-D2-D'-D3 domains, NT5B),

162 id binding domain (residues 343 to 391), the N-terminal region of MuV P (residues 1 to 194) could als

163 These results show that the N-terminal region of MyBP-C stabilizes the ON state of t

164 h muscle cells through direct binding to the N-terminal region of myocardin.

165 The N-terminal region of Ndfip1 binds to UbcH7, whereas the

166 The Hck SH2 domains impinge on the N-terminal region of Nef to stabilize a dimer conformati

167 shallow pocket adjacent to the groove in the N-terminal region of NHR trimer as a new drug target, an

168 ion is mediated by the J domain of Hsp40 and N-terminal region of NP.

169 Difference densities suggest that the N-terminal region of NS1 forms globular lobes that media

170 ffected RNA replication, indicating that the N-terminal region of NS2 is not required for NS2-3 proce

171 the SHFV PLP1s cleaving at sites within the N-terminal region of nsp1beta were produced in the in vi

172 ion between Nup50 and a region in the unique N-terminal region of Nup153 is critical for the nuclear

173 Yeast two-hybrid assay revealed that the N-terminal region of p44, instead of the traditional WD4

174 Cosedimentation studies show that the N-terminal region of PakB (residues 1-70) binds directly

175 alysis suggested at least one epitope on the N-terminal region of PEDV/TGEV N protein that contribute

176 Endophilin B2 directly binds the N-terminal region of plectin 1 via Src homology 3-mediat

177 structure of the complex between PcrH and an N-terminal region of PopB (residues 51-59), which reveal

178 interacts directly with pUL96; however, the N-terminal region of pp150 and the C-terminal region of

179 The N-terminal region of prion protein (residues 23-90) is r

180 1 cleaved eight amino acid residues from the N-terminal region of Prx1 inside the matrix, without int

181 y binding to polar residues in the conserved N-terminal region of PulG, we propose that PulM acts as

182 Truncation of the N-terminal region of PylS eliminated detectable tRNA(Pyl

183 Our results reveal that the N-terminal region of rabbit cytochrome-P4502B4, that is

184 terestingly, a hybrid protein containing the N-terminal region of Rad54, responsible for Rad51 intera

185 ere, we provide evidence suggesting that the N-terminal region of Rdh54 is not necessary for the resp

186 The 76 amino acid N-terminal region of Ref is positively charged (25/76 am

187 The putative role of the N-terminal region of rhodopsin-like 7 transmembrane biog

188 The N-terminal region of RTA is required for the reduction o

189 The long N-terminal region of RTN3 contains several newly identif

190 Scc2 binds to Scc1 through an N-terminal region of Scc1 that overlaps with its Pds5-bi

191 her demonstrate that this sequence-divergent N-terminal region of SCINs is both functionally importan

192 an artificial fusion substrate in which the N-terminal region of securin was linked to an APC/C core

193 The N-terminal region of simian hemorrhagic fever virus (SHF

194 We demonstrated that the glycine-rich N-terminal region of SPS is crucial for the SelA-tRNA(Se

195 Expression of the N-terminal region of SS4 alone did not alter the ss4 mut

196 Interestingly, the N-terminal region of SS4 alone or when fused to GS confe

197 ted versions of SS4 and a fusion between the N-terminal region of SS4 and GS in the Arabidopsis ss4 m

198 The N-terminal region of SS4 is unique among SS isoforms and

199 Remarkably, fusion of the N-terminal region of SS4 to A. tumefaciens GS restored t

200 ion mutants, we further demonstrate that the N-terminal region of TALEs is required for the initial n

201 y polyglutamine (polyQ) expansion within the N-terminal region of the ataxin-7 protein, a known subun

202 f SH2D5 and an NxxF motif located within the N-terminal region of the breakpoint cluster region.

203 ever, addition of dynactin together with the N-terminal region of the cargo adaptor BICD2 (BICD2N) gi

204 between the PTEN C-tail and a segment in the N-terminal region of the catalytic domain.

205 ssed in eukaryotic cells, the TMH-containing N-terminal region of the CbuD1884 protein trafficked to

206 e observed that HCV1, a bNAb recognizing the N-terminal region of the CD81bs, bound a soluble E2 core

207 utational analyses further indicate that the N-terminal region of the CenH3 alpha2 helix is sufficien

208 me families revealed two insertions into the N-terminal region of the CYP125 family (residues 58-67 a

209 ear localization signal (NLS) located at the N-terminal region of the foot-and-mouth disease viral po

210 The N-terminal region of the foot-and-mouth disease virus (F

211 ts the conformational space available in the N-terminal region of the fragment.

212 GMZ2 is a hybrid protein consisting of the N-terminal region of the glutamate-rich protein fused in

213 When bound by m66, the N-terminal region of the gp41 MPER adopts a conformation

214 nonneutralizing CD4-induced epitopes in the N-terminal region of the HIV-1 gp120 (A32-like epitopes)

215 d we identified a distinct domain within the N-terminal region of the HSP-16.48 protein that specifie

216 riggered by a polyglutamine expansion in the N-terminal region of the huntingtin (HTT) protein.

217 r caused by a polyglutamine expansion in the N-terminal region of the huntingtin protein (N17).

218 The N-terminal region of the longer encoded peptide directs

219 ntibodies reported thus far to recognize the N-terminal region of the membrane-proximal external regi

220 any of these sera reacted to epitopes in the N-terminal region of the molecule.

221 dent metalloprotease now shown to cleave the N-terminal region of the MUC2 mucin at two specific site

222 An N-terminal region of the PCSK9 prodomain (amino acids 31

223 by a polyglutamine (polyQ) expansion in the N-terminal region of the protein huntingtin (HTT).

224 Moreover, only the N-terminal region of the protein, which does not contain

225 rts this activity even in the absence of the N-terminal region of the protein.

226 sted to occur via the product binding to the N-terminal region of the protein.

227 ons of SP3 required sequences located in the N-terminal region of the protein.

228 in cultured cells, primarily mediated by the N-terminal region of the protein.

229 o, mediated by the coiled-coil domain at the N-terminal region of the protein.

230 in the RNA-binding motif 2 interact with the N-terminal region of the RS domain (RS1).

231 The Abbott RealTime HBV assay targets the N-terminal region of the S gene.

232 tudy, we found that a 197-aa deletion in the N-terminal region of the S protein did not alter virus (

233 is enhanced by the presence of the unfolded N-terminal region of the sequence and by destabilization

234 o characterise the mechano-sensitive compact N-terminal region of the talin rod, and show that the th

235 critical for the inhibitory function of the N-terminal region of the V protein.

236 ctedly, we found that Munc18c recognizes the N-terminal region of the vesicle-rooted SNARE, whereas M

237 istinct root mean square fluctuations in the N-terminal region of the Vik1 MHD that connects it to Ka

238 es in the juxtaposition of the less ordered, N-terminal region of their capsid proteins, VP1/2/3.

239 which could be an effect of the much shorter N-terminal region of this protein.

240 An unstructured N-terminal region of Tim10 is necessary and sufficient t

241 PrS-YjhX specifically interacts with the N-terminal region of TopA (TopA67) but not full-TopA in

242 ecific monoclonal antibodies, targetting the N-terminal region of tropomyosin, must therefore be deve

243 tudies, we identified a critical role of the N-terminal region of UBXD1 (UBXD1-N).

244 The epitope was localized to the N-terminal region of vimentin for all vimentin-reactive

245 The N-terminal region of vIRF-1 interacts directly with memb

246 he in vivo assembled particles involving the N-terminal region of VP1.

247 In addition, we show that the N-terminal region of WNK1 binds to the UV radiation resi

248 linked polyubiquitination at a lysine in the N-terminal region of YFV NS5.

249 The N-terminal regions of Amot proteins contain a conserved

250 itions to elucidate the role of the flexible N-terminal regions of H3 and H4 histones.

251 ng the presence of RNA structures within the N-terminal regions of its coding sequences.

252 cal and exhibits similar architecture to the N-terminal regions of other non-conductive type IVa pili

253 Antibodies to the N-terminal regions of the IT4var09 PfEMP1 variant (NTS-D

254 uman LDL receptor (LB2) demonstrated two key N-terminal regions of the module that were able to rescu

255 Here we demonstrate that the N-terminal regions of these two proteins form a platform

256 oplast localized, indicating that the shared N-terminal regions of these type-III effectors represent

257 mponent of the peripheral stalk binds to the N-terminal regions of two alpha-subunits.

258 Viral fusion peptides are short N-terminal regions of type-1 viral fusion proteins that

259 redictions in the C-terminal, but not in the N-terminal, region of Hhat.

260 The N-terminal region ofSdGluc5_26A protrudes into the activ

261 with RORs through either its 28 amino acids N-terminal region or its C-terminal prospero-like domain

262 Although the extended transmembrane Orai N-terminal region (Orai1 amino acids 73-91; Orai3 amino

263 inding ELISAs with N-terminal mutants and an N-terminal region peptide confirmed that this region is

264 ese results confirm the influential roles of N-terminal region (positions 7 and 8) and the loop 40-60

265 inds and stabilizes Ku80 at DSBs through its N-terminal region, promotes precise DSB rejoining, and i

266 naling, differences and are conferred by the N-terminal regions rather than the C-terminal signaling

267 h cMyBP-C antibody against the actin-binding N-terminal region reduced ADP sensitivity, indicative of

268 CalpA generates Cactus fragments lacking an N-terminal region required for Toll responsiveness.

269 rotein is composed of a largely unstructured N-terminal region (residues 1-71) and a well-folded C-te

270 CaBP4 contains an unstructured N-terminal region (residues 1-99) and four EF-hands in t

271 ight binding interaction with LcrV while the N-terminal region (residues 7-51) shows weaker interacti

272 Recurrent mutations in the N-terminal region resulted in diminished T24 phosphoryla

273 Deletion of this N-terminal region results in a 30-fold loss in affinity.

274 ing CyRPA and RIPR, and contains a conserved N-terminal region (RH5Nt) of unknown function that is cl

275 ic domain is surrounded by an O-glycosylated N-terminal region rich in Ala, Ser, and Thr (AST domain)

276 C) has a highly disordered conformation, its N-terminal region shows resonance broadening consistent

277 osine A3 receptor (A3AR) having an identical N-terminal region shows similar biological profiles to T

278 he formation of an AcAS-Cu(I) complex at the N-terminal region stabilizes local conformations with al

279 s CH1 to bind actin aided by an unstructured N-terminal region that becomes alpha-helical upon bindin

280 of troponin I (cTnI) has a unique 31-residue N-terminal region that binds cardiac troponin C (cTnC) t

281 ubiquitin E3 ligase activity, located in an N-terminal region that is not strictly required for the

282 ends on the presence of a basic unstructured N-terminal region that tethers SpaI to the membrane.

283 igher homology in the C-terminal AD than the N-terminal region, the difference in stability is derive

284 nally sulfated on tyrosine residues in their N-terminal regions, the initial site of binding to chemo

285 human FLASH can be directly joined with its N-terminal region through alternative splicing.

286 es refolding of the short, unstructured MDM2 N-terminal region to achieve its high affinity.

287 se, yet two-state folding and binding of the N-terminal region to the p53 receptor site.

288 hoGAP domain, induces strong binding of that N-terminal region to the RhoGAP domain, converting DLC1

289 kappaB activation by vFLIP only requires the N-terminal region up to the transition between the regis

290 Solution analysis of the F1L N-terminal regions using small angle x-ray scattering in

291 Wapl contains a flexible, variable N-terminal region (Wapl-N) and a conserved C-terminal do

292 In desensitization experiments, the N-terminal region was dispensable for AnxA1-induced FPR2

293 e from the proline-glutamine-rich repetitive N-terminal region was identified as the immunodominant I

294 aved the MUC2 C-terminal region, whereas the N-terminal region was unaffected.

295 In the N-terminal region we previously identified a 14 amino ac

296 downstream at noncanonical sites within the N-terminal region, whereas lower-molecular-weight LANA1(

297 imic mutant Y4E/Y31E of the 45-residue ACTN4 N-terminal region, which can inhibit actin binding by la

298 cid motif, WDXNWD, located within the unique N-terminal region, which is required for assembly of PGA

299 has RNA methyltransferase activities at its N-terminal region, which is responsible for capping the

300 tions, an extended 38-amino acid-long unique N-terminal region with still unknown functions.