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1 N-Acylphosphatidylethanolamine phospholipase D (NAPE-PLD
2 N-AS then acetylates serine 565 (S565) of COX2, and the
3 N-protein condenses with specific RNA genomic elements u
4 CTX-OCT-Alg had a negligible release in 0.1 N HCl, while the CTX-OCT was completely released after 3
5 n the water column ranged between 0 and 1287 N m(-3) and in the sediment from 239 to 13 331 N kg(-1).
6 only (1) H-(15) N dipolar couplings and (15) N chemical shifts have been routinely assessed in orient
10 side chain fast time-scale dynamics and (15)N backbone fast time-scale dynamics are fully consistent
11 e flux of other labeled tracers (such as (15)N-tracers) in any metabolite detectable by LC-MS/MS and
12 nambiguously assigned using (1)H, (13)C, (15)N, (29)Si, and (1)H DOSY NMR as well as X-ray diffractio
13 e high variability in bulk collagen delta(15)N values observed among cave bears in Romania reflects n
15 le isotope analyses (delta(13)C and delta(15)N) indicated that the elephants were not from deep rainf
18 ted muOR bound to the morphine and D-Ala(2), N-MePhe(4), Gly-ol]-enkephalin (DAMGO) nonbiased agonist
20 ed a remarkable sensitivity of 2.9 x 10(-24) N m Hz(-1/2) at millikelvin temperatures in a dilution r
21 t-principle calculations based on typical 2D N-doped carbon/RuMo nanoalloys heterostructures demonstr
22 te material by coupling DMASnBr(3) to g-C(3) N(4) , taking advantage from the combination of their op
29 mated cranial impact forces to be up to 3400 N during ramming, and prior finite element modeling stud
30 but inhibited by increased drought (-30.4%), N deposition (-31.0%), and combinations of available mul
33 those who screened positive for PTSD (7.9%, N = 42), all had co-morbid depression and/or anxiety.
34 ct conformers at cryogenic temperatures in a N(2) matrix, and subsequent narrow-band near-infrared (N
35 ot elongation is associated with aboveground N content and that overexpression of DWF1 significantly
36 replicated in African Americans from ACCORD (N = 585, P = 0.02) and in external cohorts (ACCORD-BP, O
38 for the activation of 4-methylbutyric acid (N-debenzoyl-N-(2-methylbutyryl)taxol side chain), TmAAE1
40 ition using an equivalent mixture of 4-amino-N,N,N-trimethylanilinium and 4-aminobenzenesulfonate.
41 te differential expression of aminopeptidase N and other midgut genes in an insect host, diamondback
43 We show here that the strongly amphipathic N-terminal helix of CPn0678 mediates binding to phosphol
46 d has switched its coordination mode from an N(2) S(2) (4-) cavity holding a single metal, to a binuc
47 y and functionally modular, consisting of an N-terminal effector domain (NTD) and a C-terminal regula
50 ST2 by 4% (95% CI: 1% to 7%; p = 0.002), and N-terminal propeptide of collagen III by 3% (95% CI: 0%
51 The warming-induced rise in soil CH(4) and N(2) O emissions (1.84 Pg CO(2) -equivalent/year) could
53 microsites that produce or consume CH(4) and N(2) O, such that a range of microsites occurs with both
54 were then easily converted into N-alkyl and N-acyl analogues (RX, NaHCO(3)/DMF/100 degrees C) in hig
58 n (up to 20 transgenes) for increasing C and N flows with the purpose of increasing tomato fruit yiel
59 ble condensation between CBT derivatives and N-terminal cysteine residues has been established as a b
63 rate that antibodies from patients with anti-N-methyl-d-aspartate receptor (NMDAR) encephalitis alter
69 access, near-UV-emitting linearly extended B,N-doped heptacene with high thermal stability is designe
70 r selective formation of bromo-substituted B,N,B-benzo[4]helicenes 2 a/2 b via intramolecular borylat
72 of effect in the second brain tissue (BA25, N = 60) from the same individuals and in two independent
73 arkably mild conditions (25 degrees C, 1 bar N(2)O), together with high turnover numbers (TON, up to
76 tum >11 mm) and elevated cardiac biomarkers (N-terminal pro-B-type natriuretic peptide [>40 pg/mL] or
77 This is the first research reporting boiled N. nouchali rhizome as an ideal food material to manage
82 irogenic phosphinite moiety was performed by N -> O phosphinyl migration of aminophosphines borane by
84 a translation factor directly upregulated by N-MYC, is itself a strong predictor of poor clinical out
85 posed faster via the isomer (C(6)H(4), O)(C, N, Ph) formed by P-stereomutation involving a M(B2) perm
86 atomically embedded into an in situ formed C-N network, yielding a stable compound insensitive to O(2
88 echanism allows access to both traditional C-N adducts at room temperature as well as a large range o
90 trains postnatally exposed to the carcinogen N-ethyl-N-nitrosourea developed PTMCs, which closely res
91 olds have been enantio- and chemoselectively N-oxidized using an aspartic acid containing peptide cat
94 sease-mutations cluster within the conserved N-Lip and C-Lip regions that are separated by 500-residu
96 ose with callous-unemotional traits (DBD+CU, N=198) and without callous-unemotional traits (DBD only,
97 puts and outputs to demonstrate that current N removal by US wetlands (about 860 +/- 160 kilotonnes o
98 undergo a new rearrangement to cyanopyridine N-imide 40 with an activation energy of 43 kcal/mol.
100 f CBFbeta counteracted the interference of D/N Vif mutants with A3G degradation by wild-type Vif.
102 eloping youths (N=693) and youths with DBDs (N=995), subdivided into those with callous-unemotional t
103 irmed to be the Vi monomer both de-O- and de-N-acetylated by mono- and bidimensional Nuclear Magnetic
104 DspB has increased catalytic activity on de-N-acetylated PNAG oligosaccharides, but the molecular ba
105 ivation of 4-methylbutyric acid (N-debenzoyl-N-(2-methylbutyryl)taxol side chain), TmAAE15 as a highl
107 Individuals with a primary PTSD diagnosis (N = 66) participated in a randomized clinical trial of p
108 d lack information about the receptor distal N-termini, despite the importance of the latter in signa
111 ostnatally exposed to the carcinogen N-ethyl-N-nitrosourea developed PTMCs, which closely resembled t
113 ocycle prevents the formation of a linear Fe-N(2)-Fe unit and leads to orbital interactions that are
114 angstrom X-ray crystal structure of the FigC N-citrylornithine decarboxylase reveals how the larger s
115 eved using rhodium(II) carbenes derived from N-sulfonyltriazoles and aryldiazoacetates as carbene pre
117 WV G(N) is different from other bunyavirus G(N) proteins, they all share similar domain connectivity
120 the expression of the tumor suppressor gene N-myc downstream-regulated gene 1 (NDRG1) in MCPyV gene-
123 emperatures have a profound impact on global N cycling processes with implications of a positive feed
124 , confirming the generality of the Ni(II) -> N(IV) protocol, either in the presence of bipyridine, or
125 atous visual field loss was "detected" if >= N(theta) clusters had deteriorated with p < p(Cluster),
126 ge number of self-reported Native Hawaiians (N = 3693) a functionally important, Polynesian-specific
127 zer of MEILB2 by binding to an alpha-helical N-terminus of MEILB2 and preventing MEILB2 self-associat
129 quinone analogue 2-heptyl-4-hydroxyquinoline-N-oxide inhibited C. thermarum NDH-2 activity, and its p
130 week with high-frequency MST (i.e., 100 Hz) (N = 24), medium frequency MST (i.e., 60 or 50 Hz) (N = 2
131 ), medium frequency MST (i.e., 60 or 50 Hz) (N = 26), or low-frequency MST (i.e., 25 Hz MST) (N = 36)
132 mprised exclusively of single-atom Fe(1)(II)-N(4) sites via in-temperature X-ray absorption spectrosc
134 that in addition to antigenicity, changes in N-linked glycosylation sites can alter other properties
138 with nitrogen fertilizer exhibited increased N(2)O production, by 74 times in mineral soil and 2 time
141 ine oxalates were then easily converted into N-alkyl and N-acyl analogues (RX, NaHCO(3)/DMF/100 degre
142 eterostructures demonstrate that introducing N and Mo atoms into C and Ru lattices, respectively, tri
143 derivatives olefinated through the isolated (N, O)(Ph, C(6)H(4), C) oxaphosphetanes (Channel A), wher
145 e among innate immune sensors because of its N-terminal Zalpha1 and Zalpha2 domains, which bind to nu
147 or NEMO in the activation of oncogenic c-Jun N-terminal kinase (JNK) signaling, induced by the latent
150 ary T4, right colon), biological features (K/N-RAS status), and response to chemotherapy (Response Ev
153 performance of an ensemble of QDCs of length N (N-QDCs) to assess the robustness of QDCs as a practic
158 to the monosaccharides l-fucose, d-mannose, N-acetylglucosamine, N-acetylgalactosamine, and galactos
163 formance of an ensemble of QDCs of length N (N-QDCs) to assess the robustness of QDCs as a practical
165 amyloid (A), tau (T), and neurodegeneration (N) status as required by recent biomarker classification
168 se gases nitrous oxide (N(2)O) and nitrogen (N(2)) in arable soils include high nitrate, moisture and
169 ically limiting nutrients, such as nitrogen (N) and phosphorus (P), which can reduce grassland divers
175 itu formation and photoinduced activation of N-chloroamines to give aminium radicals that enable effi
177 n enzyme responsible for the biosynthesis of N-acylethanolamines (NAEs), a family of bioactive lipid
178 tudies have reported the characterization of N-glycans in rodent brains, but there is a lack of spati
181 able to study the spatiotemporal dynamics of N(2) production due to denitrification in riparian groun
184 data and 5-kilometre grid-scale estimates of N inputs and outputs to demonstrate that current N remov
187 he degree to which variation in magnitude of N balance across irrigated maize fields in the US Corn B
190 sion preferentially blocked proliferation of N-Myc overexpressing cells, when glutamine levels were r
191 ing (ChIP-seq) was used to assess a range of N-terminal posttranscriptional modifications (marks) to
192 sed on 852 observations from 158 studies) of N fixation across three types of ecosystems with differe
193 toplasmic and nuclear protein by transfer of N-acetylglucosamine (O-GlcNAc) to serine and threonine h
194 orks operating in the glandular trichomes of N. tabacum are of pivotal significance to be undertaken.
195 sults provide a mechanistic understanding of N(2)O production in eukaryotic phototrophs and represent
196 ane depolarization blocks cellular uptake of N-acylethanolamides-lipoprotein-borne Hh pathway inhibit
197 of functional groups, providing a variety of N-H pyrroles in good yields and with high regioselectivi
198 l we sequentially enrolled 1.5-45 year-olds (N=148) into four age-descending groups, randomized 2:1 t
203 roduction of greenhouse gases nitrous oxide (N(2)O) and nitrogen (N(2)) in arable soils include high
204 g a diabetes centre in the UAE.Participants (N = 973) with different weight and glucose tolerance cat
206 slices with nociceptin/orphanin FQ peptide (N/OFQ; 500 nM), an endogenous opioid-like peptide, norma
208 n that the rate constants of the phthalimide-N-oxyl radicals' self-decay with different electron-with
212 ides a sustainable alternative for preparing N,O-biaryl compounds that are widely used as ligands and
213 rculating IL6 (interleukin-6) and NT-proBNP (N terminal pro B-type natriuretic peptide) levels were e
214 ng sulfide as an electron donor will promote N(2) O and ammonium production, which is generally not d
216 e Ab responses to different areas on protein N and S and showed that the IgM, A, and G Ab responses a
218 over the nighttime O(2) consumption rate (R(N)) in mature leaves of Arabidopsis (Arabidopsis thalian
221 m from recycled human urine; once recovered, N and P can be redirected to fertilizer production.
222 appropriate SOFs applied were able to reduce N(2)O production and maintain greater nitrate-N levels i
223 or acute inhibition of the Arp2/3 regulator, N-WASP, which is associated with enhanced signaling, inc
224 ombine the CsgG nanopore with the 35-residue N-terminal region of its extracellular interaction partn
225 e specifically, we show that acidic residues N-terminal to the substrate pTyr in EGFR and HER2 mediat
226 ide variety of transformations (acylation, S(N)Ar, silylation, solvolysis, Pd catalyzed C-S cross-cou
227 of nucleophilic substitution of hydrogen (S(N)(H)) was first applied for the direct modification of
228 onal group swap) results from a cascade of S(N)Ar reactions, which are facilitated by azidoazomethine
230 c preference of PH(2)(-) is steered to the S(N)2 reaction channel (less-destabilizing activation stra
231 electrophiles follow a hitherto unexplored S(N)2 pathway for the reaction with large transition state
233 FIDs, achieving a further increase in the S/N ratio and more effective denoising also on the transie
237 r treatment of depression (discovery sample, N=30; active replication sample, N=81; sham replication
240 (n = 206) and 1 collection of blood samples (N = 1132) of MDD cases and controls, we used epigenomic
242 his study, we identify the vesicular soluble N-ethylmaleimide-sensitive factor attachment protein rec
243 table compounds often with chemically stable N-N bonds but which are thermodynamically unstable in th
244 erein reported a series of novel substituted N-(4-amino-2-chlorophenyl)-5-chloro-2-hydroxybenzamide a
246 sically stable SACs on traditional supports (N-doped carbon, metal oxides, etc.) remains a formidable
247 e), together accounting for 72% of synthetic N fertilizer-induced NH(3) emissions from croplands in t
248 ere female) were classified into 8 A+/-/T+/-/N+/- categories according to the abnormal (+)/normal (-)
251 domain (RBD) and those directed against the N-terminal domain (NTD), indicating that both of these r
253 alidated the interaction between hTR and the N (6)-methyladenosine (m(6)A) demethylase ALKBH5 and sho
254 cetylates serine 565 (S565) of COX2, and the N-AS-acetylated COX2 induces the production of specializ
255 O-glycopeptides modified exclusively at the N-terminus would enable O-glycoproteomic methods to rely
256 s, synthetic binding proteins, that bind the N-terminal four-helix bundle (4HB) "killer" domain and n
257 se in clusters of polar residues at both the N and C termini, and deletion of up to 11 C-terminal res
258 ered the disordered region that connects the N- and C-terminal halves in many eukaryotic ABC transpor
262 We further explored its application in the N-glycan profile of a biotherapeutic monoclonal antibody
263 ified hemi- and heterozygous variants in the N-terminal domain of the A isoform of FHF2 (FHF2A).
265 trong triple bond and the nonpolarity of the N(2) molecule pose thermodynamic and kinetic challenges
266 Here we present the first analysis of the N- and O- and glycosphingolipid-glycans from total human
267 Accordingly, deletion or depletion of the N-end rule pathway ubiquitin E3 ligases in NatB mutants
268 activities involved in the synthesis of the N-glycan of the viral major capsid protein in PBCV-1 and
269 onal CI arising from the inactivation of the N-module subunits due to attrition caused by its constan
271 effects on the RNA-unwinding activity of the N-terminal cassette, with one configuration enhancing an
273 structural modeling have suggested that the N-terminal myristoylation signal and the C-terminal FXXF
274 etween mixing and freezing, we find that the N-terminal portion of M13 converts from a conformational
276 ngs of C-type lectin-like domains, where the N-terminal cysteine-rich and fibronectin domains reside
277 rin homology (PH) domains interacts with the N-terminal region comprising ARL8- and kinesin-1-binding
279 dogenous compounds, including IBC, thiamine, N(1)-methylnicotinamide (1-NMN), creatinine, carnitine,
280 gradation of target mRNAs, mediated by three N-terminal Repression Domains (RDs), which are unique to
281 MS) is an important tool for high-throughput N-glycan profiling and, upon use of tandem MS, for struc
284 2) administered intravaginally (10 mug/d) to N. gonorrhoeae-colonized mice were equally efficacious.
288 her things, the production of trimethylamine N-oxide, a proinflammatory compound associated with card
289 Wu and colleagues report that trimethylamine N-oxide (TMAO), an intestinal microbiome-dependent metab
290 ts freshness status in comparison to the TVB-N and TVC method which takes many hours to complete invo
293 nism by which the intrinsically unstructured N-terminal translocation domain (IUTD) of the endonuclea
295 with the broadly neutralizing antibody VRC01-N using a highly reproducible humanized mouse model.
297 njugation of 2-cyanobenzothiazole (CBT) with N-terminal cysteines (NCys) typically gives a luciferin
298 tion of small amounts of the Ru complex with N-oxide ligands can significantly activate single-site R
300 were compared: typically developing youths (N=693) and youths with DBDs (N=995), subdivided into tho