ライフサイエンスコーパス: NA

1 NA efficiently induces repeat contractions in HD patient

2 NA injections in HD mouse striatum reduce mutant HTT pro

3 NA-AION eyes with ODD were termed "ODD-AION"; those with

4 NA-induced contractions depend on active expansions driv

5 e other hand, we found that the remaining 26 NA substitutions were susceptible to at least one or mor

6 Of the 72 NA substitutions, 19 conferred resistance to LAN, which

7 examinations were recorded: 14% CAAP and 86% NA-LRI.

8 which included most HA (H1 to H14) and all 9 NA subtypes.

9 eparation and promotes PrP fibrillation in a NA structure and concentration-dependent manner.

10 romatic amino acids and nucleic acids (AAA + NA), tryptophan residues, nicotinamide adenine dinucleot

11 d glutamate efflux in the nucleus accumbens (NA) core during the reinstatement of cocaine-seeking.

12 e, used within the fastest and most accurate NA method for temporal networks: DynaWAVE.

13 that nicotinamide (NAM) and nicotinic acid (NA) modulate macrophage function to restrict M. tubercul

14 ysiological concentration of nicotinic acid (NA).

15 criminate even a few copies of nucleic acid (NA) and species-specific NA sequences, NAATs have become

16 lification of the cMET gene, a nucleic acid (NA) biomarker for lung cancer, and complete an ultrafast

17 nostics, single- and multiplex nucleic acid (NA) detection, with the potential to discriminate mutate

18 Currently, nucleic acid (NA) purification remains time-consuming and labor-intens

19 ess of fundamental and applied nucleic acid (NA) research depends on NA purity, but obtaining pure NA

20 However, nucleic acid (NA) sample preparation preceding dNAAT is generally labo

21 Nucleic acid (NA)-based treatments hold great potential to combat outb

22 Nucleic acids (NA) isolated from biopsy specimens had HIV quantified an

23 Naphthenic acids (NAs) are carboxylic acids naturally occurring in crude o

24 ted water (OSPW), of which naphthenic acids (NAs) are one of the main persistent toxicants.

25 Distinguishing between naphthenic acids (NAs) associated with oil sands process-affected water (O

26 Naphthenic acids (NAs) constitute one of the toxic components of the produ

27 evidence supports the role of nucleic acids (NAs) in assisting this conversion.

28 behavioral tests after SA or normal active (NA; 12:12 L:D) photoperiod exposure during gestation and

29 to record cardiac rhythm and nerve activity (NA) from the left stellate ganglion (SNA), left cardiac

30 matrices without the need for any additional NA or protein components.

31 hesion can be identified: nascent adhesions (NAs), focal complexes, and focal adhesions, ranked here

32 p (OS; Bisco, Inc.), or a negative adhesive (NA) control and subjected to 24-h storage in water, ther

33 how that human monoclonal antibodies against NA induced by vaccination and infection can be very broa

34 loma (MM) after treatment with novel agents (NA) such as thalidomide, bortezomib, and lenalidomide ma

35 MM initiated with either novel agents alone (NA), chemotherapy combined with novel agents (CCNA), or

36 city, N-linked glycosylation sites can alter NA enzymatic stability and the NA amount in virions.IMPO

37 These findings suggest that although NA-LRIs are usually not considered pneumococcal, many ca

38 These findings suggest that although NA-LRIs are usually not considered pneumococcal, many ca

39 inental stock groups (CSG) in North America (NA) and Southern Europe (SE) over the period 1971-2014.

40 ailable genomic sequences of North American (NA)-type PRRSVs (n = 355, including 138 PRRSV genomes se

41 volutionary dynamics between North American (NA)-type PRRSVs in China and in the United States.

42 Neuralgic amyotrophy (NA), also known as Parsonage-Turner syndrome, is charact

43 study the effect of supplementation with an NA gradient on the recovery of B. thailandensis persiste

44 rent antivirals, notably nucleoside analogs (NAs), exert their effect by incorporation into viral gen

45 Prophylaxis with nucleos(t)ide analogue (NA) is recommended to prevent hepatitis B virus (HBV) re

46 atients on long-term nucleos(t)ide analogue (NA) therapy; cohort B: 23 antibodies against hepatitis B

47 h LC-CR related to separate NA-dependent and NA-independent factors).

48 utant virus possessing both the NA-F144C and NA-T342A mutations was isolated from both the lung and t

49 euraminidase (NA)-like protein (NA-F144C and NA-T342A, N2 numbering) that increased the virus titers

50 erly tuned balance of the kinetics of HA and NA activities for viral entry to and release from the ho

51 we showed that the induction of both HA and NA antibodies after infection is influenced by age and s

52 The induction of both HA and NA antibodies in these cohorts was influenced by age and

53 munological memory in the dynamics of HA and NA antibody responses.

54 The reassortant virus with the HA and NA from the chicken virus, where mutations in functional

55 A(H7N9) influenza virus by balancing HA and NA functions, shedding light on an alternative approach

56 3' terminal packaging signals of the HA and NA genomic segments, which contain the RNA promoters, we

57 , we compared the antibody profile to HA and NA in two naturally infected human cohorts in Auckland,

58 identified mutations in the PB1, NP, HA, and NA virus proteins that were highly conserved in the poul

59 the AD(-)PA(+) group from the AD(+)PA(+) and NA groups.

60 cy of sporadic mutations in the PB2, PA, and NA segments.

61 c (Zn) and other metals in higher plants and NA-chelated Fe is highly bioavailable in vitro.

62 he virus circulated in turkeys (HA S141P and NA S416G) and later in chickens (HA M66I, L322Q), showed

63 rived peptides, NA(181-190) (SGPDNGAVAV) and NA(181-191) (SGPDNGAVAVL), are completely overlapping wi

64 relationship between [(11)C]PBR28 signal and NA was assessed first with regression analyses against B

65 e infected animals, whereas the NA-T342A and NA-F144C/T342A mutant viruses were detected in the nasal

66 o differences were seen between NA-FLU-v and NA-placebo.

67 rmed infections in adults, pre-existing anti-NA antibody levels >=40 were associated with a 69% (95%

68 extension induced significantly higher anti-NA IgG responses (characterized by increased in vitro an

69 asonal vaccines, however, poorly induce anti-NA antibodies, partly because of the immunodominance of

70 Preexisting anti-NA antibody titers were most predictive of reduced influ

71 seasonal vaccines do not elicit strong anti-NA responses-in part due to the immunodominance of the H

72 Our results suggest that anti-NA antibodies play a large role in reducing influenza il

73 red" viruses significantly enhances the anti-NA antibody response compared to vaccination with unmodi

74 Food and Drug Administration-approved NA inhibitors enhance anti-stem-based Fc-dependent immun

75 iruses (AIVs) carrying resistance-associated NA substitutions.

76 was mainly caused by amino acid mutations at NA residues 245, 247 (S245N/S247T; introducing an N-link

77 port a compound, naphthyridine-azaquinolone (NA), that specifically binds slipped-CAG DNA intermediat

78 No differences were seen between NA-FLU-v and NA-placebo.

79 e possibility of therapeutic synergy between NA inhibitors and anti-stem mAb treatment in humans.

80 s, there was significant variability between NA types.

81 tients despite marked HBV-DNA suppression by NA.

82 tients despite marked HBV DNA suppression by NA.

83 n (LLPS) and if this process is modulated by NAs.

84 CAAP, NA-LRI, and CXR examination visit rates declined by 49%,

85 We assessed CAAP, NA-LRI and overall rates of visits with chest radiograph

86 We assessed CAAP, NA-LRIs, and overall visits with chest radiograph (CXR)

87 We calculated CAAP, NA-LRI, and CXR examinations annual incidences from 2004

88 ent DM in a large North American HIV cohort (NA-ACCORD).

89 a role for glial activation in pain-comorbid NA, identifying in neuroinflammation a potential therape

90 % CI, 12 months to not available/computable [NA]) for gPALB2 and 6.3 months (90% CI, 4.4 months to NA

91 By further re-concentrating NAs and performing polymerase chain reaction (PCR) in a

92 ractable organics (AEOs) fraction containing NAs in the subsurface near an oil sands tailings pond.

93 N immunogenicity of nucleic acid-containing (NA-containing) amyloid fibrils in the periphery.

94 The resulting eluent contains NAs and carryover of extraction buffers.

95 Here, we review key anti-CoV NA-based technologies, including antisense oligonucleoti

96 The frequency of detected NAs in the samples varied between 14 and 44 isomer group

97 orms a base-exchange reaction with the donor NA group deriving from NAAD, produced by newly described

98 l for any future vaccines aimed at eliciting NA immunity.IMPORTANCE Data on the immunologic responses

99 ctivated ISG-expressing microglia enveloping NA-containing neuritic plaques in postmortem brains of p

100 By examining NAs from 2009 pandemic-like H1N1 viruses, we traced the

101 we examined the association of pre-existing NA, hemagglutination inhibiting, and HA stalk antibody l

102 Coordinated Regional Downscaling Experiment (NA-CORDEX) run at three spatial resolutions.

103 body repertoire is broadened by the extended NA and includes additional ADCC-active antibodies.

104 ll volumes of reagents commonly employed for NA extraction and purification.

105 l diagnostic tool to distinguish A-AION from NA-AION.

106 abrador Sea/Grand Banks for populations from NA, 26% and 24% of variance is captured by SST and PP, r

107 ed in WT mouse brain challenged with generic NA-containing amyloid fibrils.

108 he H5N1-R1 and H5N1-R2 viruses contained HA, NA, and M genes from the A(H5N1) clade 2.3.2.1a viruses

109 ccination efforts have focused mainly on HA, NA-based immunity has been shown to reduce disease sever

110 ceptor binding and subsequently balancing HA-NA functions.

111 d for both whole genomes and concatenated HA/NA sequences.

112 area without loss of avidity or disrupted HA/NA interactions showed significantly reduced NI activity

113 the highest proportion of mixed and rare HA/NA combinations, indicating increased opportunity for re

114 break clusters in a hospital setting than HA/NA sequencing.

115 animals, and their inhibitory effects on IAV NA and HA activities and on bacterial sialidases (neuram

116 nd O-acetyl-modified Sia; however, while IAV NAs were inhibited by Neu5Gc and O-acetyl modifications,

117 ly broadly protective antibodies against IBV NA have not been identified.

118 yed broad and potent capacity to inhibit IBV NA enzymatic activity, neutralize the virus in vitro, an

119 monoclonal antibodies (mAbs) that target IBV NA from an IBV-infected patient.

120 engaging residues highly conserved among IBV NAs.

121 and Cu(II)(Phe)(3) and nicotianamine: Cu(II)(NA); zinc complexes with citrate: Zn(II)(Cit)(2) and nic

122 e: Fe(III)(Glu)(2) and nicotianamine: Fe(II)(NA); copper complexes with phenylanine: Cu(II)(Phe)(2) a

123 ate: Zn(II)(Cit)(2) and nicotianamine Zn(II)(NA) and manganese complex with asparagine Mn(II)(Asp)(2)

124 sefulness of screening resistance markers in NA enzyme inhibition assays and animal models of AIV inf

125 ve surgery as a valuable treatment option in NA.

126 f structural peripheral nerve pathologies in NA, most notably hourglass-like constrictions.

127 cts was significantly reduced versus that in NA subjects (median level, 67 vs 97 mug/mg protein [P =

128 hus highlighting the importance of including NA antigenicity for consideration in the optimization of

129 nhancer of Fe bioavailability, and increased NA/DMA biosynthesis has proved an effective Fe biofortif

130 biofortified wheat diet containing increased NA, Fe, Zn and DMA (long-term exposure).

131 vide strong support for wheat with increased NA-chelated Fe as an effective biofortification strategy

132 whereas the concentrations of the individual NA isomer groups ranged between 0.2 and 44 mg L(-1).

133 n with inactivated adjuvanted vaccine induce NA-reactive responses comparable to that of H7N9 natural

134 non-CAAP lower respiratory tract infections (NA-LRI) are generally not considered pneumococcal diseas

135 non-CAAP lower respiratory tract infections (NA-LRIs) are generally not considered pneumococcal disea

136 h a similar binding profile in the influenza NA enzyme active site as those of other NAIs, oseltamivi

137 Hindlimb ischemia, NA, and hindlimb ischemia plus NA increased the magnitud

138 linked to locus coeruleus noradrenergic (LC-NA) activity affect cognition.

139 In short, we characterise the LC/ NA system within a general theory of brain function.

140 to use low dilutions (e.g., 2x) to maximize NA concentration.

141 ctively, compared to 0.407 and 0.670 of mCSM-NA, a state-of-the art model to predict the thermodynami

142 stigational vaccines or to routinely measure NA content in licensed vaccines.

143 travidin-functionalized magnetic microbeads (NA-MBs) modified with a biotinylated-anti-dsDNA (b-dsDNA

144 o rescue influenza viruses that express more NA and less HA.

145 influenza vaccine (TIV), which inhibited N1 NA from viruses isolated from humans over a period of a

146 ree broadly reactive human MAbs targeting N1 NA.

147 udy demonstrates that human antibodies to N1 NA with exceptional cross-reactivity can be recalled by

148 the ability to inhibit a wide spectrum of N1 NAs on viruses isolated between 1918 and 2018.

149 ition, the antibodies cross-inhibited the N1 NAs of highly pathogenic avian H5N1 influenza viruses.

150 on, inhibited both group 1 N1 and group 2 N9 NAs.

151 Neuraminidase (NA), the second major surface protein on the influenza v

152 Additionally, we identified a neuraminidase (NA) mutation that allowed the virus to grow in the prese

153 amivir (LAN) is a long-acting neuraminidase (NA) inhibitor (NAI) with a similar binding profile in th

154 s hemagglutinin (HA or H) and neuraminidase (NA or N).

155 emagglutinin (HA) binding and neuraminidase (NA) cleavage.

156 Haemagglutinin (HA) and neuraminidase (NA) gene sequencing have traditionally been used to iden

157 )pdm09 hemagglutinin (HA) and neuraminidase (NA) genes with genetic combinations derived from the tri

158 alogues containing the HA and neuraminidase (NA) segments from H1N1 2009 pandemic viruses or from an

159 g head and stalk regions) and neuraminidase (NA), impact influenza illness and virus transmission.

160 gainst hemagglutinin (HA) and neuraminidase (NA), the two major glycoproteins on the virus surface.

161 A virus (IAV) surface antigen neuraminidase (NA or N) showed that the conservation of N-linked glycos

162 content which provide better neuraminidase (NA)-based protection.

163 Currently, neuraminidase (NA) inhibitors are extensively used to treat influenza,

164 otal of 96 hemagglutinin (HA)/neuraminidase (NA) subtype combinations were isolated, which included m

165 tibodies induced by influenza neuraminidase (NA), like those against hemagglutinin (HA), are relative

166 ctive antibodies also inhibit neuraminidase (NA) enzymatic activity, prohibiting viral egress.

167 mal-adapting mutations in the neuraminidase (NA)-like protein (NA-F144C and NA-T342A, N2 numbering) t

168 the immunologic responses to neuraminidase (NA) is lacking compared to what is available on hemagglu

169 targeting the influenza virus neuraminidase (NA) protein can be protective and are broadly cross-reac

170 rteritic anterior ischemic optic neuropathy (NA-AION).

171 Nicotianamine (NA) is a natural chelator of Fe, zinc (Zn) and other met

172 , PS (n = 42) and nonsensitized nonallergic (NA, n = 10) patients were studied.

173 AD(-)PA(+), 9 AD(+)PA(+), and 11 nonatopic (NA) participants.

174 Noradrenaline (NA) is hypothesized to play a key role in coordinating t

175 ed hypothesis that putatively noradrenergic (NA)-dependent functions would be more strongly associate

176 ted patients with T1DM and normoalbuminuria (NA) (n = 30) or new onset MA with and without early GFR

177 newly described endolysosomal activities of NA phosphoribosyltransferase (NAPRT) and NMN adenyltrans

178 make it possible to include known amounts of NA in investigational vaccines or to routinely measure N

179 nd hepatic decompensation after cessation of NA was explored.

180 argely if not entirely due to consumption of NA-chelated Fe.

181 anced by ensuring the appropriate content of NA antigen.

182 em for singleplex and multiplex detection of NA targets in microwells down to femtomolar (fM) concent

183 dependent risk factor for the development of NA-AION, at least in younger patients.

184 also demonstrate that a therapeutic dose of NA (250 mg/kg of body weight), previously applied as imm

185 Attenuating the global effects of NA also eliminated the phasic effects of prediction erro

186 strategy for improving the immunogenicity of NA in an influenza virus vaccine.IMPORTANCE Influenza vi

187 llus gallus) model to investigate impacts of NA-chelated Fe on Fe status and gastrointestinal health

188 cation strategy and uncover novel impacts of NA-chelated Fe on gastrointestinal health and functional

189 The future prospects of NA POCT platforms are promising as they allow absolute q

190 ising as they allow absolute quantitation of NA in individuals which is essential to precision medici

191 N resistance profiling of AIVs of a range of NA subtypes improves the understanding of NAI resistance

192 The common trends at the scale of NA and SE capture 60% and 42% of the total variance of t

193 postsmolt marine survival among the 13 SU of NA and SE.

194 risk of clinical relapse after withdrawal of NA.

195 the presence and the total concentration of NAs in the samples with a Pearson correlation coefficien

196 th the distribution and the concentration of NAs in the samples, the C(8)H(14)O(2) isomer group appea

197 The averaged total concentration of NAs varied between 6 and 56 mg L(-1), among the tested p

198 t environmentally relevant concentrations of NAs in contaminated drinking water is likely negligible.

199 ested platforms based on the distribution of NAs in these samples.

200 automates magnetic bead-based extraction of NAs with a one-step transfer to dNAAT.

201 mical characterization and quantification of NAs in PW samples from six different Norwegian offshore

202 These results shed new light on the roles of NAs in PrP misfolding and TSEs.

203 bitumen from oil sands are a major source of NAs and are currently stored in tailings ponds.

204 pplied nucleic acid (NA) research depends on NA purity, but obtaining pure NAs from raw, unprocessed

205 gnificantly reduced in patients initiated on NA (2010-2014 period) compared to chemotherapy alone (ad

206 e mutant viruses each possessing NA-F144C or NA-T342A in the nasal turbinates of one or several infec

207 anted or nonadjuvanted placebo (A-placebo or NA-placebo) (2:2:1:1 ratio).

208 or nonadjuvanted (2 doses) FLU-v (A-FLU-v or NA-FLU-v) or adjuvanted or nonadjuvanted placebo (A-plac

209 These neuraminidase-derived peptides, NA(181-190) (SGPDNGAVAV) and NA(181-191) (SGPDNGAVAVL),

210 centration, we report one-step, liquid-phase NA purification that is simpler and faster than conventi

211 Purification using solid-phase NA extractions utilizes sequential additions of lysis an

212 In graminaceous plants NA serves as the biosynthetic precursor to 2' -deoxymugi

213 imb ischemia, NA, and hindlimb ischemia plus NA increased the magnitude of (99m)TcO(4)(-) uptake by 4

214 pe and single mutant viruses each possessing NA-F144C or NA-T342A in the nasal turbinates of one or s

215 grin mobility inside the adhesion potentiate NA formation.

216 ated disease after cessation of prophylactic NA therapy in patients who received rituximab-containing

217 ions in the neuraminidase (NA)-like protein (NA-F144C and NA-T342A, N2 numbering) that increased the

218 rch depends on NA purity, but obtaining pure NAs from raw, unprocessed samples is challenging.

219 (ma81K-N3(R292K)) or Q136K (ma81K-N8(Q136K)) NA substitutions, which impart in vitro susceptibility o

220 parates from the eluent, and does not reduce NA yield (measured by digital PCR).

221 This antigenic drift also reduced NA-antibody-based protection against in vivo virus chall

222 odel (within which LC-CR related to separate NA-dependent and NA-independent factors).

223 viruses were more likely than adults to show NA-only seroconversion (88% [0 to 4 yo] and 75% [5 to 19

224 influenza A viruses were more likely to show NA-only seroconversion compared to children (56% versus

225 es of nucleic acid (NA) and species-specific NA sequences, NAATs have become the gold standard in a w

226 thin 1 year (20 of 25; 80.0%) after stopping NA.

227 ation sites showed that they either support (NA Ser178) or inhibit (PB1 Thr223) virus propagation.

228 -expressing microglia exclusively surrounded NA+ amyloid beta plaques, which accumulated in an age-de

229 em for the detection of virtually any target NA, in a specific and sensitive manner.

230 be critical to any vaccine effort targeting NA immunity.

231 Ten NA substitutions reduced the susceptibility to all four

232 : 19 anti-HBe-positive patients on long-term NA treatment who achieved HBsAg loss and in whom treatme

233 : 19 anti-HBe-positive patients on long-term NA treatment who achieved HBsAg loss and in whom treatme

234 ), a larger k(off) and a smaller DeltaG than NA.

235 Our results demonstrate that NA underpins behavioral and computational responses to u

236 HA) responses, despite growing evidence that NA immunity can be protective and broadly cross-reactive

237 analysis and quantitative PCR, we found that NA inhibited gene expression of the stringent response r

238 Here, we tested the hypothesis that NA in pain patients is linked to elevations in the brain

239 Our findings suggest that NA antigenic drift impacts protection against influenza

240 The NA-F144C/T342A double mutation did not substantially aff

241 tes can alter NA enzymatic stability and the NA amount in virions.IMPORTANCE N-linked glycans are tra

242 ree end-members relevant to ascertaining the NA environmental footprint within the region: (1) OSPW;

243 tibodies either fully or partially block the NA active site or bind to epitopes distant from the acti

244 A mutant virus possessing both the NA-F144C and NA-T342A mutations was isolated from both t

245 Consequently, the NA is a promising target for influenza virus vaccine des

246 ne dinucleotide phosphate (NADP(+) ) for the NA group of nicotinic acid adenine dinucleotide (NAAD) i

247 cant changes in glutamate homeostasis in the NA core of cocaine + alcohol rats relative to rats consu

248 ased significantly from being highest in the NA group (1.62) to lowest in AD(+)PA(+) group (0.07 [P <

249 n AD(+)PA(+) group (0.07 [P < .001 vs in the NA group; P = .006 vs in the AD(-)PA(+) group]), with th

250 is/trans-UCA ratio (1.17 [P = .024 vs in the NA group]).

251 Sequence analysis showed that in the NA head domain of H1N1 IAVs, three N-linked glycosylatio

252 ral packaging signals-thereby increasing the NA content on viral particles-is a viable strategy for i

253 ese mAbs inserted long CDR-H3 loops into the NA active site, engaging residues highly conserved among

254 we hypothesize that the subdominance of the NA can be modulated if the protein is modified such that

255 ed whether extending the stalk domain of the NA could render it more immunogenic on virus particles.

256 ntigenic drift on the lateral surface of the NA head of isolates from 2009 and 2015.

257 lso accumulate at the lateral surface of the NA head.

258 As a result, the binding of the NA of A(H3N2) virus by some human monoclonal antibodies,

259 ation of N-linked glycosylation sites on the NA enzymatic head domain differs by IAV subtype (H1N1 ve

260 that the N-linked glycosylation sites on the NA head domain are required for efficient virion incorpo

261 that the N-linked glycosylation sites on the NA head domain contribute to virion incorporation and re

262 se of the immunodominance of the HA over the NA when the two glycoproteins are closely associated.

263 dly protective antibodies that recognize the NA active site of IAVs.

264 It is now time to remember the NA as we work toward improved influenza vaccines.

265 ghlights the importance of standardizing the NA antigen in seasonal vaccines to offer optimal protect

266 Antibodies targeting the NA surface antigen could also inhibit virus entry and eg

267 ding those that have broad reactivity to the NA of the 1957 A(H2N2) and 1968 A(H3N2) reference pandem

268 e lungs of the infected animals, whereas the NA-T342A and NA-F144C/T342A mutant viruses were detected

269 ntly, the buffer typically used to elute the NAs off the magnetic beads is replaced by a carefully se

270 Understanding these NA responses during natural infection is key to exploiti

271 Analysis of human antibodies to NA lags behind that of antibodies to HA.

272 This suggests that antibodies to NA may be a useful therapy and that the efficacy of infl

273 gPALB2 and 6.3 months (90% CI, 4.4 months to NA) for sBRCA1/2 mutation carriers.

274 In vitro, microglia innately responded to NA-containing amyloid fibrils.

275 oadly cross-reactive, the immune response to NA during infection is poorly understood compared to the

276 Seroconversion to NA was not influenced by age or virus type.

277 e-property study demonstrates that toxicity, NA binding capacity, and biodistribution could be balanc

278 The TPDS and TPDS-NA were treated as reference standard to establish the d

279 When compared with the 11 items TPDS-NA subscale, the FOBS validity and accuracy decreased: s

280 with the negative affect 11-items TPDS (TPDS-NA) subscale.

281 In total, we detected 55 unique NA isomer groups, out of the 181 screened homologous gro

282 Contemporary treatment regiments using NA (mainly bortezomib) were associated with a lower risk

283 ed improved allograft perfusion in LP versus NA mice.

284 IMPORTANCE Antibodies to the influenza virus NA can provide protection against influenza disease.

285 circulating A(H5N1) clade 2.3.2.1a viruses, NA and M genes from concurrently circulating A(H9N2) inf

286 reward, and reversal learning deficits, vs. NA-born WT mice.

287 Of the 74 eyes with NA-AION, 51% had ODD-AION, whereas 43% of fellow eyes wi

288 A total of 65 patients (127 eyes) with NA-AION were included (mean 41 years old).

289 s did not differ from that in the group with NA skin.

290 papillary CVI compared to both patients with NA-AION (respectively, 67.17 +/- 2.35 vs 69.66 +/- 4.18,

291 All patients with NA-AION 50 years old or younger, seen in neuro-ophthalmo

292 arteritis (biopsy-proven), 20 patients with NA-AION, and 20 control subjects were acquired with Heid

293 the prevalence of ODD in young patients with NA-AION.

294 A/Puerto Rico/8/1934 (PR8) were rescued with NA stalk domains extended by 15 or 30 amino acids.

295 io versus that in the group of subjects with NA skin (1.9 vs 1.3 [P = .008]), whereas the AD(+)PA(+)

296 After 5 years' therapy with NA, 27% and 14% had detectable HBcrAg and HBV RNA.

297 We screened viruses with NA substitutions previously found during OS and ZAN sele

298 goes LLPS, and that the PrP interaction with NAs modulates phase separation and promotes PrP fibrilla

299 ODD-AION, whereas 43% of fellow eyes without NA-AION had ODD (P = .36).

300 Most of these young NA-AION patients had ODD.