戻る
「早戻しボタン」を押すと検索画面に戻ります。

今後説明を表示しない

[OK]

コーパス検索結果 (left1)

通し番号をクリックするとPubMedの該当ページを表示します
1                                              NECA (10 microM) induced a 1.9 +/- 0.06-fold increase in
2                                              NECA activated ERK and CREB in HRECs.
3                                              NECA also increased insulin-like growth factor-I and bas
4                                              NECA and CGS21680 increased cAMP production within 10 mi
5                                              NECA and forskolin had no effect on AP-1 activation, c-j
6                                              NECA binding to GRP94 was efficiently blocked by geldana
7                                              NECA enhanced JunB binding to the murine VEGF promoter,
8                                              NECA enhanced tube formation on the matrix, whereas both
9                                              NECA failed to prevent cytokine-induced beta-cell death
10                                              NECA increases canine mastocytoma cell cAMP, Ca2+, and i
11                                              NECA induced proliferation in a concentration-dependent
12                                              NECA inhibited cytosolic protein phosphatase activity by
13                                              NECA inhibited diabetes in A2A receptor KO mice and the
14                                              NECA or N(6)-(2-iodo)benzyl-5'-N-methylcarboxamidodoaden
15                                              NECA stimulated chemotaxis in a concentration-dependent
16                                              NECA stimulation activates p38 mitogen-activated protein
17                                              NECA stimulation is blocked by the A3 AR antagonist 3-et
18                                              NECA, in parallel with the activation of ERK, also stimu
19                                              NECA-induced secretion of IL-8 and VEGF was verified by
20                                              NECA-stimulated degranulation is not prevented by pertus
21                                              NECA-treated BMDC also expressed reduced levels of MHC c
22 vating cells in the presence of IL-1, IL-1 + NECA, or IL-1 + forskolin and culturing cells in the pre
23 inding of the radioligands [3H]CGS21680, [3H]NECA, and [3H]XAC.
24 affect LPS-induced TNF-alpha and CXCL10; (4) NECA and CGS21680 similarly inhibited LPS-induced TNF-al
25 er (XAC), 5'-(N-ethyl carboxamido)adenosine (NECA), and adenosine, respectively] and reduced by coexp
26 hages with 5'-N-ethyl-carboxamido-adenosine (NECA), a nonselective adenosine A(2) receptor agonist, o
27 1 agonist), 5'-N-ethylcarboxamide adenosine (NECA) (10 muM; agonist for all adenosine receptor subtyp
28 agonist) and 5-N-ethylcarboxamide adenosine (NECA) (AdoRA2A/ADoRA2B agonist) inhibited LAK cell cytot
29 r CGS21680, 5'-N-ethylcarboxamido adenosine (NECA), UK432097 [6-(2,2-diphenylethylamino)-9-[(2R,3R,4S
30 or agonist 5'-(N-ethylcarboxamido)adenosine (NECA) and blocked by the adenosine receptor antagonist,
31  neither 5'-( N-ethylcarboxamido)-adenosine (NECA; activating the A2b adenosine receptor) nor prostag
32 ne analogue 5'-N-ethylcarboxamido-adenosine (NECA) in the absence or presence of AdoR antagonists.
33 cell surface SERT protein are elevated after NECA or sildenafil stimulation of AR/SERT-cotransfected
34 bited VEGF protein production by HRECs after NECA stimulation.
35                        The adenosine agonist NECA (100 micromol/L) increased interleukin-8 (IL-8), va
36 pts, only the nonselective adenosine agonist NECA (5'-N-ethylcarboxamidoadenosine), but not the selec
37 ffects of the nonselective adenosine agonist NECA, the relatively selective adenosine A2 agonist CV-1
38 ng regions for the 9H-purine ring in agonist NECA 3 and the 1H-[1,2,4]triazolo[1,5-c]quinazoline ring
39 n cooperativity with the orthosteric agonist NECA were different in PD81723 and VCP171; positive coop
40  the nonselective adenosine receptor agonist NECA (5'-N-ethylcarboxamidoadenosine).
41 reated with the general Ado receptor agonist NECA and abolished by Ado receptor antagonists.
42 s mimicked by the adenosine receptor agonist NECA and the A2B receptor agonist BAY60-6583.
43 he selective A(2)-adenosine receptor agonist NECA but not the A(1)-adenosine agonist CCPA replicated
44 The non-selective adenosine receptor agonist NECA effectively inhibited IAC by 79.3 +/- 2.9 % (n = 24
45               The adenosine receptor agonist NECA inhibited interferon-gamma and stimulated interleuk
46  agonist adenosine and the synthetic agonist NECA.
47  antagonist MRS 1220, but not by the agonist NECA (up to 300 nM), consistent with labeling of R.
48 namics substantially differ between agonist (NECA) and inverse agonist (ZM241385) bound receptors, wi
49 cacy to the reference high efficacy agonist, NECA, in an assay of ERK1/2 phosphorylation assay.
50 popolysaccharide (LPS) and the A2AR agonists NECA and CGS21680 synergistically augment VEGF transcrip
51 boxamidoadenosine (NECA) >> N(6)-aminobenzyl-NECA approximately 2-chloroadenosine > 2-[4-(2-carboxyet
52 on of HMC-1 with the stable adenosine analog NECA (5'-N-ethylcarboxamidoadenosine) activated p21(ras)
53 n vitro, whereas the stable adenosine analog NECA [5'-(N-ethylcarboxamido)adenosine] downregulated ex
54 13 secretion induced by the adenosine analog NECA, but did not mimic the enhanced Ag-induced degranul
55                                Adenosine and NECA also stimulated gap junctional intercellular commun
56                                Adenosine and NECA markedly induced HO-1 and blocked LPS-induced TNF-a
57 rence abrogated the effects of adenosine and NECA on TNF-alpha.
58 nduced TIMP-1 release, as both adenosine and NECA were less efficacious in augmenting TIMP-1 release
59 e anti-inflammatory effects of adenosine and NECA, which was lost in macrophages isolated from A2aR-d
60 he inhibitory effects of adenosine, CADO and NECA.
61                                  Hypoxia and NECA increased VEGF protein secretion 4.7 times, whereas
62             Adenosine (EC50: 0.5 microM) and NECA (universal adenosine receptor agonist; EC50 0.1 mic
63 ; positive cooperativity between PD81723 and NECA was reduced on alanine substitution of a number of
64 osine and the A3 receptor agonists N6-Benzyl-NECA and 1-deoxy-1-[6-[[(3-iodophenyl)methyl]amino]-9H-p
65                   Whereas Hsp90 did not bind NECA, GRP94 bound NECA in a saturable manner with a K(d)
66 se (MAPK), whereas p38 MAPK inhibitors block NECA stimulation of SERT activity, as does the protein p
67 ethy]-5-isoquinoline-sulfonamide (H8) blocks NECA, hydroxylamine, and 8-bromo-cGMP effects.
68           Whereas p38 MAPK inhibition blocks NECA stimulation of 5-HT activity, it fails to blunt sti
69 (50) < 10 ng/ml), but not of IFN-gamma, both NECA and CGS21680 synergistically up-regulate VEGF expre
70   Studies of mRNA half-life showed that both NECA and forskolin decreased the half-life of collagenas
71 Whereas Hsp90 did not bind NECA, GRP94 bound NECA in a saturable manner with a K(d) of 200 nm.
72 tokine-induced beta-cell death in vitro, but NECA strongly suppressed expression of the proinflammato
73 regulated kinase 1/2 (ERK), are activated by NECA and UTP.
74                            ERK activation by NECA or UTP is unaffected by a tyrosine kinase inhibitor
75 GF 109203X failed to block ERK activation by NECA or UTP, however, another PKC inhibitor, Ro 31-8220,
76 0 ligand on HMC-1 surface was not altered by NECA.
77  antagonists diminished activation of ERK by NECA exposure.
78  (RTI-55) whole-cell binding is increased by NECA or sildenafil, and both surface binding and cell su
79          Cyclic AMP levels were increased by NECA, and a direct adenylate cyclase activator (forskoli
80 he down-regulation of Gi proteins induced by NECA treatment and was not associated with sustained or
81             This effect is fully mimicked by NECA (nonselective agonist), largely mimicked by CCPA (A
82 mitogenic effect of adenosine is mimicked by NECA, CCPA, and R-PIA, but not by CGS21680and 2-Cl-IB-ME
83 ncrease in intracellular calcium produced by NECA.
84 )adenosine) > CHA (N6-cyclohexyladenosine) = NECA (5'-N-ethylcarboxamidoadenosine) > 2-CADO (2-chloro
85 , adenosine A2 receptor (A2R) agonists DPMA, NECA, and CGS21680 increased VEGF mRNA in a dose-depende
86 of existing surface SERTs fails to eliminate NECA stimulation of SERT.
87 agonists was 5'-N-ethylcarboxamidoadenosine (NECA) > N6-(3-iodobenzyl)-adenosine-5'-N-methyluronamide
88  > N6 benzyl 5'-N-ethylcarboxamidoadenosine (NECA) > NECA > CGS21680 > N6-cyclohexyladenosine), and t
89 tency order: 5'-N-ethylcarboxamidoadenosine (NECA) >> N(6)-aminobenzyl-NECA approximately 2-chloroade
90 osine analog 5'-N-ethylcarboxamidoadenosine (NECA) (10 microM) increased mRNA expression of IL-1beta,
91  HEK-293 cells, N-ethylcarboxamidoadenosine (NECA) activates endogenous A2BARs that signal through Gs
92 tive agonist 5'-N-ethylcarboxamidoadenosine (NECA) but not by the A3-selective agonist N6-(3-iodobenz
93 ptor agonist 5'-N-ethylcarboxamidoadenosine (NECA) decreased collagenase production by IL-1-stimulate
94 ptor agonist 5'-N-ethylcarboxamidoadenosine (NECA) increased both arginase activity (EC(50)=261.8 nM)
95 sine agonist 5'-N-ethylcarboxamidoadenosine (NECA) increased expression of interleukin-8 (IL-8), basi
96 (AR) agonist 5'-N-ethylcarboxamidoadenosine (NECA) induces an increase in 5-HT uptake Vmax in rat bas
97 sine agonist 5'-N-ethylcarboxamidoadenosine (NECA) or the adenylate cyclase activator forskolin.
98 ptor agonist 5'-N-ethylcarboxamidoadenosine (NECA) prevented diabetes development in both MLDS-challe
99 ptor agonist 5'-N-ethylcarboxamidoadenosine (NECA) protected CD73(-/-) mice against T. gondii-induced
100 In this report, N-ethylcarboxamidoadenosine (NECA) was used to investigate the nucleotide binding pro
101 ptor agonist 5'-N-ethylcarboxamidoadenosine (NECA) while cell activity was monitored with whole-cell
102 nstrate that 5'-N-ethylcarboxamidoadenosine (NECA), a nonspecific ADO analogue, and 2-p-(2-carbonyl-e
103 adenosine or 5'-N-ethylcarboxamidoadenosine (NECA), a stable adenosine analog, to modify the response
104  AR agonist, 5'-N-ethylcarboxamidoadenosine (NECA), at an early stage after immunization had an inhib
105 ptor agonist 5'-N-ethylcarboxamidoadenosine (NECA), in a concentration-dependent manner, increased bo
106 gonist [(3)H]5'-N-ethylcarboxamidoadenosine (NECA).
107 ptor agonist 5'-N-ethylcarboxamidoadenosine (NECA; IC50 = 30 nM; p < 0.0001, analysis of variance).
108 E-NECA], [3H]5'-N-ethylcarboxamidoadenosine [NECA], and R(-)N6-(2-phenylisopropyl)adenosine [R-PIA])
109 ptor agonist 5'-N-ethylcarboxamidoadensoine (NECA) increased fasting blood glucose and slowed glucose
110 ive agonist, N(6)-ethylcarboximidoadenosine (NECA, 0.03-0.1 micromol/kg, ip.), lowered 1-4 Hz amplitu
111                                     Finally, NECA-dependent VEGF secretion and reporter activity were
112                       Conditioned media from NECA-activated HMC-1 stimulated human umbilical vein end
113 nzyl 5'-N-ethylcarboxamidoadenosine (NECA) &gt; NECA > CGS21680 > N6-cyclohexyladenosine), and this was
114 SCH58261 > HE-NECA = CSC = CGS 21680 = XAC &gt; NECA = R-PIA.
115                                     In [(3)H]NECA displacement assays, GRP94 displayed binding intera
116 ation of another radiolabeled agonist, [(3)H]NECA, from the receptor.
117                           On the other hand, NECA and CGS-21680 dose-dependently potentiated the prod
118 2-hexynyl-5'-N-ethylcarboxamidoadenosine [HE-NECA], [3H]5'-N-ethylcarboxamidoadenosine [NECA], and R(
119 opropyl)adenosine [R-PIA]) was SCH58261 > HE-NECA = CSC = CGS 21680 = XAC > NECA = R-PIA.
120 everal selective A(2B) antagonists inhibited NECA-stimulated calcium mobilization in HEK-A(2B) cells.
121 ntagonists, enprofylline and IPDX, inhibited NECA-stimulated proliferation, ERK activation, cell migr
122                                          LPS/NECA treatment also increased HIF-1alpha protein and DNA
123 es from the VEGF promoter did not affect LPS/NECA-induced VEGF promoter activity, suggesting that NF-
124 F expression is strongly up-regulated by LPS/NECA in macrophages from A(3)-/- but not A(2A)-/- mice,
125 Taken together, these data indicate that LPS/NECA-induced VEGF expression involves transcriptional re
126 acrophages in an NF-kappaB-dependent manner; NECA strongly increased these levels in an A2AR-dependen
127 s verified using RT-PCR and ELISA; 10 microM NECA increased IL-13 concentrations in HMC-1 conditioned
128 d collagenase promoter activity, and neither NECA nor forskolin blocked this action.
129 ersed the capacity of dibutyryl cAMP but not NECA to increase pp1 activity (p < 0.01, n = 5) in keepi
130  the zeta-isoform, and prevents UTP- but not NECA-induced ERK activation.
131                    The stimulatory action of NECA, a non-selective analogue, was blocked neither by t
132 ses, whereas injection of the same amount of NECA at a late stage inhibited the Th1 response but had
133  that cAMP mediates the inhibitory effect of NECA on collagenase production.
134 ly dissociated, that the enhancing effect of NECA on Th17 responses was modulated by gammadelta T cel
135 es, indicating that the beneficial effect of NECA was due to immunomodulation.
136                 This proliferative effect of NECA was inhibited by the addition of anti-human VEGF an
137                                The effect of NECA was reversed by the selective A2B receptor antagoni
138 R antagonist MRS1754 prevented the effect of NECA, we conclude that the stimulatory effect of adenosi
139 e of A(2B) receptors prevented the effect of NECA.
140 ermeant analog of cGMP, mimic the effects of NECA on 5-HT uptake, whereas the protein kinase G (PKG)
141           We also showed that the effects of NECA on Th1 and Th17 responses were completely dissociat
142                               The effects of NECA were not significantly attenuated by either the A(2
143 mino-NECA caused any of the above effects of NECA.
144 congener completely inhibited the effects of NECA.
145                           Focal ejections of NECA evoked outward currents in all cells tested and red
146 e with K(I) determinations for inhibition of NECA-stimulated cAMP accumulation in HEK-A(2B) cells.
147  site (-1093 to -1086) resulted in a loss of NECA-dependent VEGF reporter activity.
148 chniques indicated that GRP94 bound 1 mol of NECA/mol of GRP94 dimer.
149                To accommodate the 0.5 mol of NECA:mol of GRP94 binding stoichiometry observed for the
150 d alone in the absence or in the presence of NECA, produced no IgE.
151            Inhibition of IAC by adenosine or NECA was eliminated by substituting GDP-beta-S for GTP i
152               We examined whether LPS and/or NECA induce HIF-1alpha expression.
153 ith extremely high concentrations of CADO or NECA, mild inhibition of LAK cytotoxicity was observed t
154 sence of the A(2A) ligands SCH58261, CSC, or NECA, or in the absence of A(2A) receptors.
155  agonist 2-p-(2-carboxyethyl) phenethylamino-NECA caused any of the above effects of NECA.
156 ) agonist 2-p-(2-carboxyethyl)phenethylamino-NECA nor the selective A(3) agonist N(6)-(3-iodobenzyl)-
157 osine > 2-[4-(2-carboxyethyl)phenethylamino]-NECA (CGS21680) > N(6)-aminobenzyladenosine.
158 agonist 2-p-(2-carboxyethyl)phenylethylamino-NECA (CGS 21680) had no effect on expression of these an
159 OP with the following rank order of potency: NECA > CV-1808 > > R-PIA = CGS-21680.
160                Transfection of HRECs reduced NECA-stimulated migration of cells by 47.3+/-1.2% (P=7x1
161 hanism of action was pre-translational since NECA decreased collagenase, but not stromelysin or tissu
162  The findings of this study demonstrate that NECA and forskolin decrease collagenase gene expression
163                                We found that NECA inhibited TNF-alpha and IL-12 in a concentration-de
164 -/-) and A(2B)AR(-/-)mice, it was shown that NECA modulates TNF-alpha, IL-12, IL-10, and CD86 respons
165                                          The NECA-evoked current was abolished by the A(1) antagonist
166  the SK channel blocker apamin decreased the NECA-induced current by 42 +/- 7%.
167  channel blocker rTertiapin-Q diminished the NECA-evoked inhibitory current by 56 +/- 12%, whereas th
168                      The SK component of the NECA-evoked current coincided with an increase in intrac
169 d that the response of gammadelta T cells to NECA was determined by their activation status.
170 interleukin (IL)-6 production in response to NECA due to activation of protein kinases A and C.
171 orskolin, but weakly affects the response to NECA or UTP.
172     Moreover, a decrease in cAMP levels upon NECA stimulation of naive macrophages was counterbalance
173 AR agonists in inducing IL-10 production was NECA > IB-MECA > CCPA >/= CGS21680, and the A(2B)AR anta
174 W156ECL2 decreased VCP171 cooperativity with NECA.
175 an B lymphocytes cocultured for 12 days with NECA-stimulated HMC-1 produced 870 +/- 33 pg IgE per 10(
176                                     LPS with NECA strongly up-regulates VEGF expression by macrophage
177                       Treatment of PMNs with NECA increased the pp1 activity of crude membrane prepar
178                     Further stimulation with NECA did not increase HIF-1alpha promoter activity, indi
179       Analysis of the pEC(50) values of XAC, NECA, and adenosine for the ABA-X-BY630-occupied A(3)-re

WebLSDに未収録の専門用語(用法)は "新規対訳" から投稿できます。
 
Page Top