ライフサイエンスコーパス: NMR method

1 the rotational echo double resonance (REDOR) NMR method.

2 coordinate accuracy within the limits of the NMR method.

3 evel using a new high-resolution solid-state NMR method.

4 ent vineyards were determined using the SNIF-NMR method.

5 ned from the pulse gradient spin echo (PGSE) NMR method.

6 solved by a hybrid solution and solid-state NMR method.

7 16-mer consensus DNA using multidimensional NMR method.

8 l (1)H-(1)H correlated and (1)H-(13)C-edited NMR methods.

9 nalysis as well as directly through multiple NMR methods.

10 domain of FIP2 in the absence of Rab11 using NMR methods.

11 rystallography and of a larger M2 peptide by NMR methods.

12 ermined by both x-ray crystallography and by NMR methods.

13 s with quinuclidine bases were determined by NMR methods.

14 , fluorescence, and high-resolution solution NMR methods.

15 ar-weight proteins, using modern solid state NMR methods.

16 nd joining (NHEJ), has been determined using NMR methods.

17 -observe and (15)N,(1)H-HSQC protein-observe NMR methods.

18 s well as two-dimensional 13C-1H correlative NMR methods.

19 respectively, which can be characterized by NMR methods.

20 active site of ARD' inaccessible to standard NMR methods.

21 ture of apo NosL has been solved by solution NMR methods.

22 d the backbone dynamics by multi-dimensional NMR methods.

23 o BIV TAR RNA determined using heteronuclear NMR methods.

24 blished using mass spectrometry and multiple NMR methods.

25 axation optimized spectroscopy (TROSY)-based NMR methods.

26 to enhance aqueous solubility) with SecA by NMR methods.

27 ligomers was confirmed via 1D and 2D (NOESY) NMR methods.

28 design of (1)H, (15)N, or (13)C solid-state NMR methods.

29 the engineered protein with multidimensional NMR methods.

30 ss were determined through conventional (1)H NMR methods.

31 rain 385-99 (WN-rED3) has been determined by NMR methods.

32 structure of human SWI1 ARID using solution NMR methods.

33 have been investigated with high-resolution NMR methods.

34 and determined high-resolution structures by NMR methods.

35 lts along with two-dimensional heteronuclear NMR methods.

36 guests in a cylindrical host was studied by NMR methods.

37 means of conventional and new field-cycling NMR methods.

38 een determined in solution though the use of NMR methods.

39 phospholipid bicelles using high-resolution NMR methods.

40 hia coli under resting conditions by in-cell NMR methods.

41 otein, Rd-apocyt b(562), by multidimensional NMR methods.

42 mined in solution at pH 5.0 by heteronuclear NMR methods.

43 turally characterized using multidimensional NMR methods.

44 e II TGFbeta receptor determined by solution NMR methods.

45 sample, can readily be measured by solution NMR methods.

46 was determined by standard 3-D heteronuclear NMR methods.

47 n assigned using COSY, NOESY, HSQC, and HMBC NMR methods.

48 ctral data deduced by UHPLC-DAD-ESI-HRMS and NMR methods.

49 V-1 reverse transcriptase (RT) determined by NMR methods.

50 0-tetrahydrobenzo[a]pyrene was studied by 2D NMR methods.

51 solution structure of NuiA was determined by NMR methods.

52 urified, and analyzed using multidimensional NMR methods.

53 with intact vinyl substituents was solved by NMR methods.

54 ants for the formation of pseudorotaxanes by NMR methods.

55 atch site in bold), as determined by 2D (1)H NMR methods.

56 ng heteronuclear, (1)H,(15)N-high-resolution NMR methods.

57 and rotational echo double-resonance (REDOR) NMR methods.

58 (1)H NMR signals on the basis of standard 2D NMR methods.

59 analysis of the protein by multidimensional NMR methods.

60 iology when measured and analyzed by in vivo NMR methods.

61 ex, as characterized by crystallographic and NMR methods.

62 of Escherichia coli DnaJ has been solved by NMR methods.

63 B2 (3b) firmly established by 2-dimensional NMR methods.

64 he Rous sarcoma virus has been determined by NMR methods.

65 ned using heteronuclear and triple resonance NMR methods.

66 l coactivator GCN5 has been determined using NMR methods.

67 ive to the nature of the heme ligand, and by NMR methods.

68 human Hdj1 previously determined by solution NMR methods.

69 /K(+)-ATPase by a combination of solid-state NMR methods.

70 due SL2 oligoribonucleotide by heteronuclear NMR methods.

71 from this family has been determined by (1)H NMR methods.

72 mum), using volumetric, gravimetric, and PFG-NMR methods.

73 ion and structure determination by classical NMR methods.

74 s and congeners are determined using dynamic NMR methods.

75 ly characterised using HPLC-MS/MS, 1D and 2D NMR methods.

76 gned as a pyrano[3,2-b]pyran on the basis of NMR methods.

77 ly amenable to drug screening by traditional NMR methods.

78 as first determined through modern RDC-based NMR methods.

79 pplied advanced multidimensional solid-state NMR methods.

80 o hours and allows their characterization by NMR methods.

81 sparsely populated to observe by traditional NMR methods.

82 lide structures were determined by 1D and 2D NMR methods.

83 rough analysis of the signals with 1D and 2D NMR methods.

84 multiprotein complexes using solution-state NMR methods.

85 multidimensional nuclear magnetic resonance (NMR) methods.

86 D using solution nuclear magnetic resonance (NMR) methods.

87 stallography and nuclear magnetic resonance (NMR) methods.

88 with solid-state nuclear magnetic resonance (NMR) methods.

89 al heteronuclear nuclear magnetic resonance (NMR) methods.

90 al heteronuclear nuclear magnetic resonance (NMR) methods.

91 GLC, and HPLC) and spectral (UV, MS, and 1H NMR) methods.

92 Here the solid-state NMR method, 2D polarization inversion spin exchange at m

93 A combination of (13)C and (23)Na NMR methods allowed the recording of intra- and extracel

94 ation of solute hydrogen bond acidities, the NMR method allows the determination of A values for indi

95 bazole complexes with an AATT sequence by 2D NMR methods also supported a minor groove complex of the

96 Employing a combination of NMR methods and computer-based structural refinement, st

97 The structure was elucidated by 2D NMR methods and confirmed by X-ray crystallographic anal

98 determined by detailed two-dimensional (2D) NMR methods and confirmed by X-ray crystallographic anal

99 e dsRNA binding surface of NS1A-(1-73) using NMR methods and describe the 2.1-A x-ray crystal structu

100 ntally measure the pKa of O2' by kinetic and NMR methods and find it to be lower in the presence of d

101 Recent developments that have accelerated 2D NMR methods and improved quantitation have made these me

102 ts were determined using a combination of 2D NMR methods and mass spectrometry.

103 These new proteins are shown by NMR methods and molecular dynamics simulations to be ver

104 its diagnostic mutant, Y123W, using solution NMR methods and molecular dynamics simulations.

105 2D NMR methods and molecular modeling using NMR-derived res

106 oligonucleotides have been examined using 2D NMR methods and molecular modeling.

107 structure of the isolated CBP TAZ1 domain by NMR methods and show that it has the same structure in t

108 has been elucidated by crystallographic and NMR methods and shows a high degree of structural conser

109 Two-dimensional NMR methods and spectral synthesis were employed to assi

110 of human DNA pol lambda via multidimensional NMR methods and the ARIA program.

111 its dynamic properties were investigated by NMR methods and with the aid of a model compound lacking

112 ducts has been defined by X-ray analyses and NMR methods, and both chelating and monodentate binding

113 ted mutants, dynamic motion information from NMR methods, and correlated motions from MD simulations

114 y structure have recently been determined by NMR methods, and does not have precedent among known DNA

115 oil and humin, by both CP-MAS and DP-MAS 13C NMR methods, and that the problem is more serious for CP

116 ar quadruplex has been previously studied by NMR methods, and the present X-ray structure is in accor

117 The solid-state NMR method appears to be especially useful for determini

118 improvements in sensitivity and resolution, NMR methods are becoming more amenable to dissecting the

119 ucleotide exchange, high-resolution solution NMR methods are being applied in studying signaling of t

120 ge protein complexes by traditional solution NMR methods are difficult due to a priori requirement of

121 The NMR methods are often combined with statistical analysis

122 Solid state NMR methods are required to analyze biomass as a functio

123 ted sensitivity, nuclear magnetic resonance (NMR) methods are attractive because of their simplicity,

124 We have used complementary chemical and NMR methods as an approach to improving our understandin

125 metimes ambiguous given the range of current NMR methods available.

126 We present a new and efficient NMR method, BLUU-Tramp (Biophysics Laboratory University

127 ystem, the methodology used demonstrates how NMR methods can provide important insights into the stru

128 more easily measured, certain PET and (13)C NMR methods can quantify total regional signal activity

129 Consequently, an NMR method capable of measuring delta(13)C per thousand

130 was solved in aqueous buffer using 1D and 2D NMR methods combined with restrained molecular dynamics.

131 ng into a third dimension via fast-hybrid 3D NMR methods combining the speed of ultrafast 2D NMR with

132 Compared with traditional NMR methods, data acquisition is easy and data analysis

133 ties of phospholipid bilayers, using several NMR methods, demonstrates that the two peptides insert t

134 ve been investigated by variable-temperature NMR methods, demonstrating that the intramolecular racem

135 , by using a combination of multidimensional NMR methods, density functional theory calculations and

136 One of the main goals of NMR method development is to increase the sensitivity of

137 ed by broad lines which make direct study by NMR methods difficult; this broadening arises from confo

138 entional imaging techniques, in- and on-cell NMR methods do not provide spatial information on cellul

139 or XAG region of duplexes elude discovery by NMR methods (especially because of the flexible nature o

140 ese NOE effects demonstrate a solution (19)F NMR method for analysis of tertiary contacts in high mol

141 saturation transfer (DEST), a novel solution NMR method for characterizing, at atomic resolution, the

142 atly extends the range of application of the NMR method for determination of residue-specific, side-c

143 co-workers disclosed a straightforward (19)F-NMR method for determining the log P values of fluorocar

144 An NMR method for determining the three-dimensional structu

145 n transfer difference (STD) is a widely used NMR method for ligand screening, the selection of specif

146 A recently developed solid-state NMR method for measurement of depths in membrane systems

147 Here we describe a solution-NMR method for structural characterization of UCP2.

148 l and obtain an unbiased and high-throughput NMR method for the analysis of nucleobase preference in

149 A novel 31P NMR method for the determination of purity for the milit

150 A new NMR method for the study of ligand-protein interactions

151 to the influence of hydrogen bonding and to NMR methods for chemical kinetics, including 2D-EXSY spe

152 NMR methods for detecting false positives will be analyz

153 h uniquely supplements X-ray diffraction and NMR methods for investigating solution conformations of

154 l benefit of the combination of SABRE and 2D NMR methods for rapid characterization of low-concentrat

155 the use of multidimensional MAS solid-state NMR methods for resolving and assigning resonances.

156 Unlike earlier NMR methods for solving the structures of protein-ligand

157 ive to traditional X-ray crystallography and NMR methods for structure-based drug design is described

158 r may help in the development of solid-state NMR methods for studying interhelical contacts in membra

159 e analyzed by high-resolution solution-state NMR methods for the first time.

160 gomer with only G.C bp's in the XGGY site by NMR methods for the first time.

161 y, there is great interest in development of NMR methods for the study of multicomponent systems in t

162 nts from another nuclear magnetic resonance (NMR) method for global fold determination of large prote

163 l solution-state nuclear magnetic resonance (NMR) methods for structure determination of Dsy0195, a h

164 ructural characterization of biomolecules by NMR methods frequently requires the enrichment of magnet

165 orated diffusion ordered spectroscopy (DOSY) NMR method hand-in-hand with theoretical calculations.

166 discriminator by LC-MS, further LC, MS, and NMR methods have been applied in a coordinated effort to

167 Solid-state NMR methods have been extensively applied to characteriz

168 High-resolution solid-state NMR methods have been used to analyze the conformation o

169 NMR methods have been used to characterize the structure

170 Isothermal titration calorimetry (ITC) and NMR methods have been used to independently investigate

171 Pulsed field gradient NMR methods have determined the temperature-dependent di

172 where X-ray crystallography and traditional NMR methods have failed to produce structural data.

173 Pulsed-field gradient NMR methods have now followed gradient-dependent changes

174 dimensional (2D) nuclear magnetic resonance (NMR) methods have shown to be an excellent analytical to

175 ein structures determined by either x-ray or NMR methods, if the observed (13)C(alpha) chemical shift

176 NMR methods in combination with mutagenesis and biochemi

177 able to isolate, we could characterize it by NMR methods in DMF-d7, a solvent in which it is stable a

178 we used a hybrid of solution and solid-state NMR methods in lipid bilayers and bicelles.

179 It has also been achieved by NMR methods in proteins up to 50 kilodaltons (kDa) in si

180 advantage of combining X-ray scattering and NMR methods in structural studies of dynamic, multidomai

181 Using nuclear magnetic resonance (NMR) methods, in this study we characterized the associa

182 The structures were elucidated by using 2D-NMR methods including an INADEQUATE experiment.

183 ormone and retinoid receptors using multiple NMR methods including methyl chemical shifts, coupling c

184 ion (XRD) and in solution using multinuclear NMR methods (including DOSY, EXSY, and COSY), electrospr

185 In the study presented here, isotope-edited NMR methods, including (15)N and (13)C relaxation measur

186 The unconventional NMR method introduced and validated in this work will li

187 A simple solution NMR method is presented for pucker determination of five

188 A solution-state NMR method is proposed to investigate the dynamics of pr

189 d for structure determination by traditional NMR methods is currently long, but improved hardware, au

190 Rh of alphaB-crystallin as derived from both NMR methods is found to be fully consistent with this re

191 inetic, and in one case variable-temperature NMR methods is the process of mu-phosphide bridge format

192 In contrast to established NMR methods, it does not depend on rapid exchange betwee

193 cture has been determined by two-dimensional NMR methods, molecular modeling, and molecular dynamics

194 We used three complementary NMR methods, namely amide group chemical shift titration

195 s probed by X-ray crystallography and by the NMR method of isotopic perturbation in water, in two apr

196 investigation of the H-bond symmetry by the NMR method of isotopic perturbation.

197 anion was determined in chloroform using the NMR method of isotopic perturbation.

198 Different (13)C NMR methods of determining triad distributions in two po

199 While proton-based NMR methods of fragment screening (FBS) have been well d

200 Recently devised NMR methods of measuring residual dipolar couplings prov

201 Using the solution NMR methods of residual dipolar coupling analysis, we de

202 -AKAP peptide complexes obtained by solution NMR methods, one with Ht31(493-515) and the other with A

203 Recent NMR methods permit direct detection of hydrogen bonds th

204 at precludes characterization by traditional NMR methods permits the observation of DEST.

205 nctions in health and numerous diseases, the NMR method presented here potentially opens a new chapte

206 Our NMR method presents a precise and robust measure of RAS

207 ructures of multidomain proteins by solution NMR methods presents a number of unique challenges relat

208 fluorescence and nuclear magnetic resonance (NMR) methods, proflavine has been identified, through a

209 lication of these ultrafast multidimensional NMR methods provides the opportunity to determine the st

210 Using NMR methods providing single-residue resolution and quan

211 increases in the Stokes radius determined by NMR methods result from replacement of five isoleucine/v

212 rmediate peptide concentrations, solid-state NMR methods reveal that chrysophsin-1 is aligned paralle

213 using X-ray crystallography and (19)F-based NMR methods, revealing the nature of the catalytically r

214 Here we describe a new NMR method, SALMON (solvent accessibility, ligand bindin

215 The performance of a variety of NMR methods (SGO, IGAIM, CSGT) were also examined but we

216 ng in both enzymes as determined by solution NMR methods show some striking similarities.

217 estigations of the structure and dynamics by NMR methods show that G37A retains the average WT struct

218 ith respect to the bilayer, established with NMR methods, shows that the N-terminal helix of EF-1 is

219 determination of this symmetric oligomer by NMR methods, specifically in sorting ambiguous interatom

220 n contrast to more conventional quantitative NMR methods, stem coaxial inserts are placed into the sa

221 A, we applied a combination of heteronuclear NMR methods, such as heteronuclear single quantum cohere

222 Here, we highlight recent progress in the NMR methods tailored to investigate allostery with the g

223 icability of a simple one-dimensional proton NMR method that exploits enhanced spin diffusion among p

224 We have developed an NMR method that selectively edits for organophosphorus c

225 1 order of magnitude lower than established NMR methods that employ direct protein detection for Kd

226 es in micelles was determined using solution NMR methods that rely on the measurement of backbone (1)

227 ) RNA is presented using recently introduced NMR methods that rely on the measurement of residual dip

228 se relaxation optimized spectroscopy (TROSY) NMR methods that Rev1-BRCT domain directly interacts wit

229 We have determined by solution NMR methods the atomic resolution structure of an unphos

230 ted RNA structures in the PDB were solved by NMR methods, the usefulness of NMR is still limited by t

231 sional (1)H and three-dimensional (1)H-(15)N NMR methods; the rotational dynamic properties of the pr

232 We developed a novel (13)C NMR method to assess effects of free fatty acids on mole

233 -phosphate (G-6-P) combined with a novel 13C-NMR method to assess intracellular glucose concentration

234 We present a paramagnetic NMR method to determine intermolecular structure restrai

235 We describe a simple and reliable NMR method to distinguish viscosity effects from binding

236 We used a field-cycling NMR method to observe boron pure quadrupole resonance of

237 Here, we present a cost-efficient NMR method to quantify the rotational dynamics of guanin

238 Application of the stopped-flow NMR method to the study of the kinetics of 1-hexene poly

239 We used NMR methods to characterize Rheb tethered to nanodiscs,

240 In the present study we use NMR methods to define a length scale for the FF I-N tran

241 e determined by chemical and high resolution NMR methods to define the features of each serotype.

242 Here, we use a combination of NMR methods to detect four distinct sparsely populated a

243 We have employed heteronuclear NMR methods to determine the pK(a) values and time scale

244 Here, we have used NMR methods to determine the solution structures of the

245 Here we use NMR methods to determine the structure of a Lys63-linked

246 We have used NMR methods to determine the structure of the calcium co

247 Here, we used NMR methods to determine which SipD residues are affecte

248 We use high-resolution (1)H solution NMR methods to establish the location of the Antp(43-58)

249 we use multidimensional (1)H/(15)N solution NMR methods to establish the structural and dynamics bas

250 ogues) and high resolution field cycling 31P NMR methods to estimate internal correlation times (tauc

251 We used solid-state NMR methods to examine amyloid formed in vitro from reco

252 We have used solid-state NMR methods to examine polypeptide and hydrate ordering

253 The application of rapid MAS NMR methods to investigate proton distributions in a wid

254 ructure of human cterRAP74, and we have used NMR methods to map the cterFCP-binding sites for both ct

255 We have used heteronuclear NMR methods to probe the loop conformations in solution

256 a formamido group, was recently found using NMR methods to recognize T*G mismatched base pairs.

257 e widths enabled the use of multidimensional NMR methods to resolve overlapping (31)P signals.

258 The feasibility of applying NMR methods to stable isotope-labeled, protease-cleaved,

259 ent study, we present previously undescribed NMR methods to study the interactions of proteins with t

260 will increase the applicability of solution NMR methods to the characterization of nanomaterials.

261 We have applied GC and NMR methods to the study of intermediates found in methy

262 e observed and characterized by conventional NMR methods under conditions in which the interaction wo

263 -SL2 complex was determined by heteronuclear NMR methods using (15)N,(13)C-isotopically labeled NC pr

264 We report that competition-based NMR methods, using 2OG as a reporter ligand, can be used

265 the I-domain of LFA-1 has been determined by NMR methods, using a model-based approach to nuclear Ove

266 The unconventional NMR method validated in this work will likely prove inva

267 An NMR method was developed for determining binding sites o

268 ted by Fru-2,6-P2 in intact animals, a novel NMR method was developed using [U-13C]glucose and 2H2O a

269 A nuclear magnetic resonance (NMR) method was developed to quantify cations in mineral

270 Using heteronuclear NMR methods we have investigated the domain interactions

271 ere, using the power of nonuniformly sampled NMR methods we investigate the folding pathway of amyloi

272 Using NMR methods, we characterized the secondary structure of

273 Furthermore, using NMR methods, we conclusively demonstrated that 6 binds t

274 imensional and three-dimensional solid-state NMR methods, we find that Delta113-120 PrP23-144 fibrils

275 Here, using HPLC-UV, LC-MS, and NMR methods, we identify a novel activity of fusion prot

276 Using NMR methods, we mapped the interaction of M50 with a hig

277 Using analytical ultracentrifugation and NMR methods, we show here that a membrane-soluble peptid

278 Using homonuclear rotational resonance NMR methods, we show that the internuclear distances bet

279 (13)C magic-angle-spinning NMR methods were applied to investigate structural and d

280 ification, and quantification of the drug by NMR methods were surveyed, as well as the use of NMR-bas

281 Double-resonance 17O/51V NMR methods were used as confirmation of the assignments

282 Heteronuclear NMR methods were used to assign resonances in the comple

283 In a previous study, (1)H NMR methods were used to correlate the effects of crypti

284 In the present study, NMR methods were used to correlate the effects of crypti

285 Solution NMR methods were used to determine a high resolution str

286 In this work, NMR methods were used to determine the solution structur

287 Heteronuclear NMR methods were used to determine the solution structur

288 In the present work, NMR methods were used to determine the solution structur

289 Solid-state NMR methods were used to examine the size and heterogene

290 In situ X-ray diffraction (XRD) and NMR methods were used to follow the structural changes t

291 Two-dimensional relaxation NMR methods were used to investigate the correlation tim

292 In this study, NMR methods were used to investigate the sequence depend

293 In this study, heteronuclear NMR methods were used to study the structures of the DNA

294 NMR methods were used to track R*-triggered guanine nucl

295 spectrometry and nuclear magnetic resonance (NMR) methods were thus used to directly characterize the

296 In this study, nuclear magnetic resonance (NMR) methods were used to investigate the transit of sin

297 Nuclear magnetic resonance (NMR) methods were used to study whether there are differ

298 resolution two-dimensional pure-shift zCOSY NMR method with homonuclear band-selective decoupling in

299 inor groove adduct structure was observed by NMR methods with all Watson-Crick base pairs intact, and

300 ement with models obtained using traditional NMR methods with larger restraint sets.