ライフサイエンスコーパス: NRIP1

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1 tion complex containing the p50 effector and NRIP1.

2 ent of bone metastasis in breast cancer, and NRIP1 (21q21) encodes an ER cofactor and has a role in t

3 Nuclear receptor interacting protein (Nrip1), also known as RIP140, is a co-regulator for nucl

4 Bioinformatic analysis identified Nrip1 at Vpq3 as a candidate gene.

5 d that treatment with retinoic acid enhanced NRIP1 binding to RARalpha RNA in situ hybridization conf

6 ith an accumulation of chloroplast-localized NRIP1 defense protein and H2O2 in the nucleus.

7 ssor nuclear-receptor-interacting protein 1 (Nrip1; encoded by the gene Nrip1) is essential for ovula

8 NRIP1 encodes a nuclear receptor transcriptional cofacto

9 RARalpha RNA in situ hybridization confirmed Nrip1 expression in the developing urogenital system of

10 c kidney rudiments, retinoic acid stimulated Nrip1 expression, whereas a pan-RAR antagonist strongly

11 ced IGF1 and delayed age of VP compared with Nrip1(+/+) females.

12 Nrip1(-/-) females have significantly reduced IGF1 and d

13 tions in the estrogen receptor cofactor gene NRIP1 in 12% of patients.

14 nfirmed an evolutionarily conserved role for NRIP1 in renal development.

15 nuclear receptor interacting protein 1 gene (NRIP1) in all seven affected members.

16 As a consequence, NRIP1 interacts with N only in the presence of the p50 e

17 NRIP1 is a functional rhodanese sulfurtransferase and is

18 ic alleles that delay sexual maturation; and Nrip1 is involved in regulating sexual maturation and ma

19 acting protein 1 (Nrip1; encoded by the gene Nrip1) is essential for ovulation.

20 We validated six genes (KIAA1243, NRIP1, MADH9, NME3, TPD52L, and ABCG2) to be estrogen-re

21 These data indicate that dominant NRIP1 mutations can cause CAKUT by interference with ret

22 Unlike wild-type NRIP1, the altered NRIP1 protein did not translocate to the nucleus, did no

23 o date (microarray, RNA-Seq and PAS-Seq) are NRIP1 (RIP140), a transcriptional co-regulator linked to

24 activity of the transcriptional co-repressor Nrip1 (RIP40).

25 more, mice heterozygous for a null allele of Nrip1 showed a CAKUT-spectrum phenotype.

26 Interestingly, NRIP1 that normally localizes to the chloroplasts is rec

27 dentified an N receptor-interacting protein, NRIP1, that directly interacts with both N's TIR domain

28 Unlike wild-type NRIP1, the altered NRIP1 protein did not translocate to

29 n of nuclear receptor interacting protein-1 (NRIP1), which influences glucose and lipid metabolism, t

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