ライフサイエンスコーパス: Native American

1 l populations (European, Asian, African, and Native American).

2 were Hispanic; 13, African; 8, white; and 2, Native American.

3 black, Asian/Pacific Islander, Hispanic, and Native American.

4 scent populations but not among Europeans or Native Americans.

5 he primary sources of health problems facing Native Americans.

6 tics in the risk for substance dependence in Native Americans.

7 3.3 for Asian/Pacific Islanders and 3.1 for native Americans.

8 iberia and a possible homeland for ancestral Native Americans.

9 pe-specific invasive disease potential among Native Americans.

10 substantially lower for blacks, Asians, and Native Americans.

11 precise time estimates for the emergence of Native Americans.

12 amined in skeletal muscle of 153 nondiabetic Native Americans.

13 ssociation both in Finns and in Southwestern Native Americans.

14 resistance syndrome (IRS) among nondiabetic Native Americans.

15 asured in Europeans, Africans, Japanese, and Native Americans.

16 d minorities including African, Hispanic and Native Americans.

17 rphisms and alcohol dependence in a group of Native Americans.

18 are potentially troublesome or sensitive for Native Americans.

19 ultigenerational knowledge and experience of Native Americans.

20 n the United States were used extensively by Native Americans.

21 ucleotide polymorphisms mostly restricted to Native Americans.

22 rying allele DYS199 T) largely restricted to Native Americans.

23 equency in modern Asians, Australasians, and Native Americans.

24 ncidence was highest in blacks and lowest in Native Americans.

25 landers than to any present-day Eurasians or Native Americans.

26 he Ainu and Polynesians than he is to modern Native Americans.

27 ia and were directly related to contemporary Native Americans.

28 tion directly ancestral to many contemporary Native Americans.

29 1 [0.021-0.022]; Asian: 0.037 [0.036-0.039]; Native American: 0.010 [0.0076-0.013]), lower quartile h

30 ents were black, 2% were Hispanic, 0.3% were Native American, 1% were Asian, and 90% were white, resp

31 Black (20.9% [95% CI, 20.8%-21.1%]), Native American (14.5% [14.2%-14.9%]), and Hispanic (13.

32 ), white (14.0% and 32.6%, respectively) and Native American (19.2% and 43.4%, respectively), respond

33 P < .001; Asian: 3.16 [2.68-3.73], P < .001; Native American: 2.11 [1.45-3.08], P < .001), lower hous

34 1%) and among non-Hispanic blacks (170%) and Native Americans (241%) compared to non-Hispanic whites

35 anics differed significantly from that among Native Americans (3.1% vs. 8.9%, P=0.01).

36 mong 27 705 past-year alcohol or drug users, Native Americans (31.5%), adolescents of multiple race/e

37 for sampling) were 1.3% for white, 2.2% for Native American, 4.0% for black, 9.6% for Hispanic, and

38 spanic whites, blacks (-30%), Asians (-19%), Native Americans (-42%), and Hispanics (-29%) all had lo

39 y, whereas the United States' population was Native American 500 years ago but is overwhelmingly Old

40 comparatively prevalent among adolescents of Native American (9.7%) and multiple race/ethnicity (8.8%

41 for blacks (95% CI, 50% to 62%), and 37% for Native American (95% CI, 17% to 58%).

42 ed Rapanui, we found statistical support for Native American admixture dating to AD 1280-1495 and Eur

43 t studies have reported genetic evidence for Native American admixture in present-day indigenous inha

44 ere we directly test the hypothesis that the Native American admixture of the current Rapa Nui popula

45 ed odds of substance-related disorders among Native Americans, adolescents of multiple race/ethnicity

46 A major factor for the population decline of Native Americans after European contact has been attribu

47 anics, non-Hispanic blacks, and non-Hispanic Native American/Alaska Natives.

48 y, defined as self-reported black, Hispanic, Native American, Alaskan Native, Native Hawaiian, or Pac

49 Gene flow from the MA-1 lineage into Native American ancestors could explain why several cran

50 ely to have occurred after the divergence of Native American ancestors from east Asian ancestors, but

51 an Upper Palaeolithic Mal'ta population into Native American ancestors is also shared by the Anzick-1

52 the recent mixing of African, European, and Native American ancestries, has resulted in different et

53 admixed population of African, European, and Native American ancestries, have the highest asthma prev

54 ohort (n = 1998) and evaluated the effect of Native American ancestry (NAA) and diet on biomarkers fo

55 th pancreatitis included genetically defined Native American ancestry (P < .001), older age (P < .001

56 apMap contain modest (but nonzero) levels of Native American ancestry (~0.4%).

57 nome-wide SNPs for predicting and estimating Native American ancestry and admixture levels.

58 ciation between local European, African, and Native American ancestry and BDR, adjusting for genomic

59 ombia harbor substantially more European and Native American ancestry as a result of their complex ad

60 s the ancestry, we showed that the choice of Native American ancestry could affect the local ancestry

61 ilobase in segments inferred to have diploid Native American ancestry from the genomes of Mexican and

62 Our data thus suggest that the Native American ancestry in contemporary Easter Islander

63 opulations to identify 324 highly predictive Native American ancestry informative markers (AIMs).

64 Furthermore, we estimate that 14 to 38% of Native American ancestry may originate through gene flow

65 ted the proportion of African, European, and Native American ancestry using genome-wide data.

66 st significant peak was 6p21.32-p22.1, where Native American ancestry was associated with lower IgE l

67 Native American ancestry was associated with lower odds

68 of genomic variation that co-segregated with Native American ancestry was associated with risk of rel

69 .1) at which local African, European, and/or Native American ancestry was significantly associated wi

70 higher exposure to asparaginase, and higher Native American ancestry were independent risk factors f

71 hat any of these individuals had substantial Native American ancestry.

72 sociations with retinopathy were present for Native American ancestry; country of origin; health insu

73 Also, the observed low Native-American ancestry (6-8%) was mostly introduced in

74 les from 60 global populations, including 19 Native American and 15 indigenous North Asian groups.

75 eviously possible, we assembled data from 52 Native American and 17 Siberian groups genotyped at 364,

76 etected genome-wide patterns consistent with Native American and European admixture.

77 ntributions to the Mestizo FRDA gene pool by Native American and European genes were 76-87% and 13-24

78 are the result of two-way admixture between Native American and European populations or of three-way

79 s showing high frequency differences between Native American and European populations.

80 pulse into the Americas independent of both Native American and Inuit expansions.

81 Two populations, Native American and Inuit, showed an excess rather than

82 haplotypes were associated with SSc in both Native American and Japanese patients with limited scler

83 abian ancestries, 2) Kalash ancestry, and 3) Native American and Northern European ancestries.

84 of ancestry-informative markers validated in Native American and other populations.

85 udicial decisions that Kennewick Man was not Native American and that therefore NAGPRA did not apply.

86 e-grain intake was lowest among youth of the Native American and white races and among youth of high

87 4-h EE measures in 509 healthy subjects (368 Native Americans and 141 whites) while subjects consumed

88 which were spread throughout the Americas by Native Americans and adapted to a wide range of environm

89 ojects: newborn screening for SCID in Navajo Native Americans and B-cell reconstitution in patients w

90 sians, Asian Indians, African Americans, and Native Americans and did not differ by adiponectin assay

91 populations, particularly African Americans, Native Americans and Hispanic Americans, are disproporti

92 ive disorder found among Athabascan-speaking Native Americans and is manifested by the absence of bot

93 For more than 6,000 years, Native Americans and modern breeders have exploited the

94 te to type 2 diabetes susceptibility in both Native Americans and the Old Order Amish.

95 in a second population-based sample of 3,723 Native Americans and the published DIAGRAM study.

96 ation about genetics and genetic research to Native Americans and thereby to improve informed decisio

97 Nine European, seven Asian (including Native American), and three African mitochondrial DNA (m

98 were Asian/Pacific Islander, 63 (0.8%) were Native American, and 228 (2.8%) were other.

99 were Asian/Pacific Islander, 211 (0.5%) were Native American, and 2947 (6.3%) were other.

100 os, who typically inherit a mix of European, Native American, and African ancestry.

101 arkers in at least 232 new Latino, European, Native American, and African samples, and we selected a

102 recent (within the last 500 years) African, Native American, and European ancestry.

103 2 NASH was more common in children of Asian, Native American, and Hispanic ethnicity.

104 tive traits were analyzed in 536 nondiabetic Native Americans, and ASK1 expression was examined in sk

105 en OR = 0.75, 95% CI = 0.58-0.96; Hispanics, Native Americans, and whites showed no significant assoc

106 ven to extinction in a blitzkrieg fashion by Native Americans approximately 13,000 years ago.

107 the recognized maternal founding lineages of Native Americans are at least 15, indicating that the ov

108 Blacks, Hispanic Americans, and Native Americans are known to be at higher risk for type

109 ty among the following racial/ethnic groups: Native Americans, Asian/Pacific Islanders, blacks, white

110 The ratio of ENKCL to PCTL-NOS among Native Americans, Asians/Pacific Islanders, and Hispanic

111 ferences that include substantial numbers of Native American attendees.

112 e = 74.6%, range = 45.0%-96.7%), followed by Native American (average = 18.1%, range = 2.1%-33.3%) an

113 , with Pacific Islanders, Asian Indians, and Native Americans being considerably more prone to develo

114 1775 CE)-reduced the self-limiting effect of Native American burns on fire spread.

115 en, the cumulative prevalence is 1 in 5; for Native American children, 1 in 7.

116 o improve science learning, especially among Native American children.

117 We studied two cohorts of Native American children: a birth cohort of 50 children

118 ent of the isolates in MCG-2 originated from Native American clinics, and 90% belonged to two PFGE ty

119 came from patients who were treated at five Native American clinics.

120 recovered from patients who were treated at Native American clinics.

121 eta (beta), and theta (theta) EEG power in a Native American cohort of 322 individuals to take advant

122 vide a unique genetics education program for Native American college and university students.

123 ical sites spanning approximately 3,500 y of Native American, colonial, and historical occupation.

124 MCG-2 strains spread to four additional Native American communities and 20 other communities.

125 g 242 individuals aged <6 months-78 years in Native American communities between 2007 and 2009.

126 at CA-MRSA in Wisconsin likely originated in Native American communities in the early 1990s and since

127 D) (all ages; years 1994-2007) isolates from Native American communities.

128 trains recovered from outpatients treated at Native American community clinics.

129 pes associated with an outbreak of MRSA in a Native American community in 1992.

130 curring metals in abandoned mine wastes in a Native American community in northeastern Arizona were i

131 c ancestry is Polynesian, with no detectable Native American component.

132 their last sex partner (African American and Native American).Conclusions.

133 rought forward supporting the possibility of Native American contact prior to the European "discovery

134 he northeast Asian affinities of present-day Native Americans contrast with a distinctive morphology

135 ses of the fecal steroids in 1000-2000-y-old Native American coprolites found in the dry caves of Nev

136 ded to compare the Inuit findings with other Native American data.

137 pean admixture, but also a contribution from Native Americans dating to 1280-1495 AD, demonstrating e

138 e-climate relationships were strongest after Native American depopulation-following mission establish

139 rn Eurasian genetic signatures in modern-day Native Americans derive not only from post-Columbian adm

140 Here we show that Native Americans descend from at least three streams of

141 genome-wide data to show that some Amazonian Native Americans descend partly from a Native American f

142 ociation was greater in Hispanic children of Native American descent (beta=2.3; P=0.004) than in non-

143 ts were replicated in a population sample of Native American descent (top hit rs1611115, P = 4.1 x 10

144 Native American discourse, in contrast, tends to describ

145 ter their arrival to the Americas, ancestral Native Americans diversified into two basal genetic bran

146 ns from Latin America and Alaska showed that native American dogs originated from multiple Old World

147 s systematically discouraged the breeding of native American dogs.

148 e American groups in South America than with Native Americans elsewhere, providing further support fo

149 ype (Finns, empirical P = .004; Southwestern Native Americans, empirical P = .02).

150 status epilepticus, older age, and Black and Native American/Eskimo race; patients admitted to a rura

151 specific ancestries (e.g. European, African, Native American, etc).

152 mixture mapping by comparing levels of local Native American, European, and African ancestry between

153 subcontinental source populations within the Native American, European, and African segments of the a

154 ean populations or of three-way admixture of Native American, European, and West African populations.

155 and potentially ancient substructure within Native American, European, and West African source popul

156 erica has been the site of ongoing mixing of Native Americans, European settlers, and Africans (broug

157 ction were both high information content for Native American/European ancestry (measured as the stand

158 We present 2 Native American families with a total of 5 affected pers

159 portionate contribution of European male and Native American female ancestry to present-day populatio

160 Native American fisheries were focused on nearshore oyst

161 upplements in the United States were used by Native Americans for similar purposes.

162 The major Native American founding lineage, haplogroup M3, account

163 onian Native Americans descend partly from a Native American founding population that carried ancestr

164 we focused our map on markers distinguishing Native American from other ancestries and restricted it

165 tes risk haplotype had a frequency of 50% in Native Americans from Mexico but was rare in Europeans a

166 Genetic Education for Native Americans (GENA) was a National Human Genome Rese

167 The long-term goal of Genetic Education for Native Americans (GENA), a project funded by the Nationa

168 mixture of European mutant FRDA genes in the Native American gene pool that existed prior to contact

169 at this SNP was highly correlated with local Native American genetic ancestry (P = 1.8 x 10(-8)).

170 ionship and requested repatriation under the Native American Graves Protection and Repatriation Act (

171 Among the Native American groups for whom genome-wide data are ava

172 istently indicated a single common origin of Native American groups from Central and South America.

173 uan individual shares more alleles with some Native American groups in South America than with Native

174 ad a higher incidence of AITL and ENKCL; and Native Americans had a lower incidence of PTCL-NOS (all

175 ith increased risk of ASD, as were Asian and Native American haplogroups A and M, with odds ratios ra

176 will probably increase extensively when all Native American haplogroups reach the same level of phyl

177 can origin, belonging to one of four primary Native American haplogroups.

178 that, of the nine unique haplotypes found in Native Americans, haplotypes 1C and 1F are the best cand

179 lience in oyster populations under long-term Native American harvest, sea-level rise, and climate cha

180 demographic impact of European contact with Native Americans has remained unclear despite recent int

181 teria for a substance-related disorder, with Native Americans having the highest prevalence of use (4

182 cept of unique African, European, Asian, and Native American HPV-16 variants.

183 ated with substance dependence phenotypes in Native Americans include OPRM1, CRN1, COMT, GABRA2, MAOA

184 found that the ancestors of all present-day Native Americans, including Athabascans and Amerindians,

185 t in the etiology of substance dependence in Native Americans, including studies of heritability, lin

186 rvations of high frequency of albinism among Native Americans, including the Hopi, Zuni, Kuna, Jemez,

187 ricana Medik.), once a staple food source of Native American Indians, produces protein-rich tubers, t

188 r was generally greater among men, white and Native American individuals, younger and previously or n

189 ontrolled, randomised trial enrolled healthy Native American infants aged 6 months or younger who wer

190 ewick Man, referred to as the Ancient One by Native Americans, is a male human skeleton discovered in

191 orts (n = 23 424), including whites, blacks, Native Americans, Japanese American men, and Hispanic me

192 o Native American populations, although most Native Americans lack protective variants seen in other

193 oss between a wild sunflower and a primitive Native American landrace that has not been the target of

194 Beringia, this gave rise to the predominant Native American lineage, M3 (10-11-11-10), which crossed

195 western Eurasians and near the root of most Native American lineages.

196 n highlanders (>3500 m) comparing them to 16 Native American lowlanders.

197 %; black, 12%; Hispanic, 12%; Asian, 4%; and Native American, < 1%) with neuroblastoma were included.

198 These data suggest that Native American male lineages were derived from two majo

199 Follow-up data were available for 290 Native Americans (median follow-up time: 6.6 years).

200 ensitive education about genetic research to Native American medical students and college and univers

201 ectional facilities, and among sports teams, Native Americans, men who have sex with men, and militar

202 heories (epistemological orientations) among Native Americans (Menominee) and European American child

203 Being female; Native American; middle-aged; widowed, separated, or div

204 ation in human STAC3 causes the debilitating Native American myopathy (NAM), but the nature of how St

205 AC3 is the genetic basis of the debilitating Native American myopathy (NAM).

206 ase variant in STAC3 that has been linked to Native American myopathy (NAM).

207 eas expression of Stac3W280S (containing the Native American myopathy mutation) partially restored Ca

208 ontrol subjects, n = 998) and one additional Native American (n = 2,531) sample.

209 further genotyped in independent samples of Native American (n = 3,723) and Old Order Amish (n = 486

210 re examined among 135 African American (AA), Native American (NA), and Caucasian (CA) women (55+/-11

211 was asserted that Kennewick Man was neither Native American nor closely related to the claimant Plat

212 such dynamics in 19th century, post-contact Native Americans on the western Great Plains is especial

213 The mutation was not carried by the three Native Americans or 360 patients from Asia or the Pacifi

214 cts primarily persons who are Asian, Latino, Native American, or Asian Indian.

215 ic white people, and men and women of Asian, Native American, or unkown race/ethnicity who are referr

216 the majority of the mtDNA haplotypes were of Native American origin, belonging to one of four primary

217 r individuals with albinism who listed other Native American origins, nor has it been reported in any

218 ted in both Finns (P = .01) and Southwestern Native Americans (P = .03).

219 Blacks (P < .001) and Native Americans (P = .04) had a higher prevalence of hi

220 nemic-euglycemic clamp among 536 nondiabetic Native Americans (P = 0.02).

221 5898099 was replicated in a second sample of Native Americans (P = 0.04, 1.22 [1.01-1.47]), while tha

222 nic blacks, Asians or Pacific Islanders, and Native Americans (P<0.05 for all comparisons) and that t

223 th populations (Finns, P = .01; Southwestern Native Americans, P = .008), and the GABRA6 1519T allele

224 gesic (mean, 7.4; 95% CI, 4.0-10.8) than non-Native American patients (mean, 11.2; 95% CI, 7.2-15.2;

225 score (mean, 6.5; 95% CI, 3.6-9.4) than non-Native American patients (mean, 8.1; 95% CI, 6.3-9.9; t3

226 Native American patients also received less postsurgical

227 A retrospective chart review of 21 Native American patients and a control group who underwe

228 Native American patients had a statistically lower numer

229 Medical staff attending Native American patients should be aware that response t

230 We noted that our Native American patients were less likely than others to

231 Black and Native American patients with neuroblastoma have a highe

232 for Asian patients, 0.95 (0.52 to 1.73) for Native American patients, and 0.95 (0.60 to 1.50) for pa

233 small population size and limited number of Native American patients, PTCL subtype frequencies in th

234 ernal contribution of African, European, and Native American peoples to the genetic heritage of Mexic

235 ical data needed to assess the links between Native American population decline and ecological change

236 trically interviewed samples, a Southwestern Native American population sample (N = 433) and a Finnis

237 d little evidence of a recent contraction in Native American population size.

238 nome-wide patterns of African, European, and Native American population structure within and among Hi

239 e associated with susceptibility to SSc in a Native American population with a high disease prevalenc

240 Genetic studies in a Native American population with high prevalence of using

241 results from a recent genome-wide scan on a Native American population with systemic sclerosis, and

242 present study, we show that albinism in one Native American population, the Navajo, is caused by a L

243 ht, which likely occurred in a European or a Native American population.

244 e overall high prevalence of obesity in this Native American population.

245 groups and three chlorinated pesticides in a Native American population.

246 he Medieval Climate Anomaly (950-1250 CE) as Native American populations adopted intensive maize agri

247 een the opposite ends is significant only in Native American populations and in one African populatio

248 f uniparentally inherited genetic systems in Native American populations and the comparison of these

249 groups as well as the most likely ancestral Native American populations as the ancestry, we showed t

250 Native American populations declined between 1492 and 19

251 Pre-Columbian (pre-1492 CE), maize-dependent Native American populations in the midcontinental United

252 ancestors, but before the diversification of Native American populations in the New World.

253 available African, European, East Asian and Native American populations reveals strong genetic ties

254 It existed in early Native American populations several thousand years ago b

255 ly, we find evidence of a deep divergence in Native American populations that predates the Anzick-1 i

256 e not revealed any risk variants specific to Native American populations, although most Native Americ

257 ifferentiates them from other Aboriginal and Native American populations.

258 astigmatism were higher than reported in non-Native American populations.

259 influence the phenotypic variation in extant Native American populations.

260 n American (PR 1.86; 95% CI: 1.42-2.45), and Native American (PR 1.87; 95% CI: 1.48-2.35) race were i

261 , the differences between Paleoamericans and Native Americans probably resulted from in situ evolutio

262 included younger age, male gender, Black or Native American race, a higher burden of medical comorbi

263 d with increasing age, male sex, Asian race, Native American race, and symptoms of weight loss and vo

264 dependence were generally greater among men, Native Americans, respondents aged 18 to 44 years, those

265 g in the staggered abandonment of many major Native American river valley settlements and large urban

266 ), blacks (RR, 1.17; 95% CI, 1.03-1.33), and Native Americans (RR, 1.72; 95% CI, 1.07-2.77) had incre

267 se associations replicated in an independent Native American sample (1.19, P = 0.04, for rs11003125)

268 which results in SCID in Athabascan-speaking Native Americans (SCIDA).

269 Although Native Americans seem to be genetically most closely rel

270 n the earliest American skeletons and modern Native Americans, separate origins have been postulated

271 and demonstrating that southern Altaians and Native Americans share a recent common ancestor.

272 Subsequent gene flow resulted in some Native Americans sharing ancestry with present-day East

273 dence has a substantial genetic component in Native Americans, similar in magnitude to that reported

274 he maize-based agriculture practiced by many Native American societies in eastern North America at th

275 are becoming aware of the use of herbals by Native American societies; many botanicals sold today as

276 The curriculum was pretested with Native American students, medical and general university

277 Our reconstruction suggests that Native Americans suffered a significant, although transi

278 find that Kennewick Man is closer to modern Native Americans than to any other population worldwide.

279 Among these nondiabetic Native Americans, the IRS was associated with a twofold

280 changes in socioecological systems from the Native American to the current period drove shifts in fi

281 STC-2 added race (black/Native American) to STC-1 and identified 89% of cases wh

282 379 preschool children who are members of a Native American tribe having a high prevalence of astigm

283 e cannabis use disorder were higher for men, Native Americans, unmarried individuals, those with low

284 odel, but European, Asian, and Siberian plus Native American variations did.

285 Resistant rootstocks derived from native American Vitis are the primary control tool.

286 that Y-chromosomal diversity among the first Native Americans was greater than previously recognized.

287 that maize, a dietary staple of southwestern Native Americans, was transported over considerable dist

288 rom the admixture of Europeans, Africans and Native Americans, which started over 400 years ago and h

289 tance use is widespread among adolescents of Native American, white, Hispanic, and multiple race/ethn

290 Among a population of Choctaw Native Americans with the highest prevalence of SSc yet

291 nd genetically closely related to modern-day Native Americans, with no close affinity to east Asians.

292 regions of Europe, and forced relocation of Native Americans within the US.

293 wer rates of advanced cancer among Asian and Native American women persisted when the cohort was stra

294 omen were more likely than white, Asian, and Native American women to have large, advanced-stage, hig

295 African-American, Hispanic, Asian, and Native American women were more likely than white women

296 Among Japanese American and Hispanic men and Native American women, the Framingham functions systemat

297 Here, Native American Y chromosomes are detected on the Polyne

298 Among the remaining 5% of Native American Y chromosomes is haplogroup RPS4Y-T, fou

299 The second major group of Native American Y chromosomes, haplogroup M45, accounted

300 nificantly more prevalent among men, whites, Native Americans, younger and unmarried adults, and thos